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- ArticleOctober 2024
Embryo Graphs: Predicting Human Embryo Viability from 3D Morphology
- Chloe He,
- Neringa Karpavičiūtė,
- Rishabh Hariharan,
- Céline Jacques,
- Jérôme Chambost,
- Jonas Malmsten,
- Nikica Zaninovic,
- Koen Wouters,
- Thomas Fréour,
- Cristina Hickman,
- Francisco Vasconcelos
Medical Image Computing and Computer Assisted Intervention – MICCAI 2024Pages 80–90https://doi.org/10.1007/978-3-031-72083-3_8AbstractEmbryo selection is a critical step in the process of in-vitro fertilisation in which embryologists choose the most viable embryos for transfer into the uterus. In recent years, numerous works have used computer vision to perform embryo selection. ...
- ArticleOctober 2024
Automatic Registration of SHG and H&E Images with Feature-Based Initial Alignment and Intensity-Based Instance Optimization: Contribution to the COMULIS Challenge
AbstractThe automatic registration of noninvasive second-harmonic generation microscopy to hematoxylin and eosin slides is a highly desired, yet still unsolved problem. The task is challenging because the second-harmonic images contain only partial ...
- research-articleOctober 2024
Enhanced tissue slide imaging in the complex domain via cross-explainable GAN for Fourier ptychographic microscopy
- Francesco Bardozzo,
- Pierpaolo Fiore,
- Marika Valentino,
- Vittorio Bianco,
- Pasquale Memmolo,
- Lisa Miccio,
- Valentina Brancato,
- Giovanni Smaldone,
- Marcello Gambacorta,
- Marco Salvatore,
- Pietro Ferraro,
- Roberto Tagliaferri
Computers in Biology and Medicine (CBIM), Volume 179, Issue Chttps://doi.org/10.1016/j.compbiomed.2024.108861AbstractAchieving microscopy with large space-bandwidth products plays a key role in diagnostic imaging and is widely significant in the overall field of clinical practice. Among quantitative microscopy techniques, Fourier Ptychography (FP) provides a ...
Highlights- Generative Neural network to generate Fourier Ptychographic Microscopy phase maps.
- Low-resolution real and imaginary components of complex amplitude as GAN input.
- High-resolution, wide FoV phase-contrast reconstruction of ...
- research-articleJuly 2024
Phase retrieval from integrated intensity of auto-convolution
AbstractUltra-fast optical pulses are the most ephemeral sensing paradigm ever devised, examining events over incredibly brief timescales with broadband illumination. A consequence of sensing at timescales lower than a picosecond is that pulse ...
Highlights- Ultrafast pulse characterization is built largely on auto-correlation datasets.
- Tensor iterative hard thresholding and gradient techniques demonstrate algorithmic superiority.
- These methods are applied to a condensed measurement ...
- research-articleJune 2024
Enhancing medical image analysis with unsupervised domain adaptation approach across microscopes and magnifications
Computers in Biology and Medicine (CBIM), Volume 170, Issue Chttps://doi.org/10.1016/j.compbiomed.2024.108055AbstractIn the domain of medical image analysis, deep learning models are heralding a revolution, especially in detecting complex and nuanced features characteristic of diseases like tumors and cancers. However, the robustness and adaptability of these ...
Highlights- F2DA for stain normalization in histopathology and microscopic slides.
- Converting bounding box labels to precise segmentation for detailed analysis.
- Framework using Multi-Axis attention for robust, multi-faceted malaria detection.
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- research-articleFebruary 2024
Localization and phenotyping of tuberculosis bacteria using a combination of deep learning and SVMs
- Marios Zachariou,
- Ognjen Arandjelović,
- Evelin Dombay,
- Wilber Sabiiti,
- Bariki Mtafya,
- Nyanda Elias Ntinginya,
- Derek J. Sloan
Computers in Biology and Medicine (CBIM), Volume 167, Issue Chttps://doi.org/10.1016/j.compbiomed.2023.107573AbstractSuccessful treatment of pulmonary tuberculosis (TB) depends on early diagnosis and careful monitoring of treatment response. Identification of acid-fast bacilli by fluorescence microscopy of sputum smears is a common tool for both tasks. ...
Highlights- First automated detection of Mtb bacteria with a dual fluorescence staining.
- The proposed network achieves excellent performance at localising bacteria in a field of view.
- Detection of Mtb cells stained with two fluorescence dyes ...
- research-articleDecember 2023
Is attention all geosciences need? Advancing quantitative petrography with attention-based deep learning
AbstractRecent advances in deep learning have transformed data-driven geoscientific analysis. In particular, the adoption of attention mechanism in deep learning has received considerable interest and shown impressive results that can surpass traditional ...
Highlights- This study proposes a novel attention-based deep learning workflow to advance quantitative petrography.
- The Super Petrography model outperforms other conventional and deep learning methods for image super-resolution tasks.
- Multi-...
- ArticleApril 2024
Self-supervised Single-Image Deconvolution with Siamese Neural Networks
Data Augmentation, Labelling, and ImperfectionsPages 157–166https://doi.org/10.1007/978-3-031-58171-7_16AbstractInverse problems in image reconstruction are fundamentally complicated by unknown noise properties. Classical iterative deconvolution approaches amplify noise and require careful parameter selection for an optimal trade-off between sharpness and ...
- ArticleOctober 2023
Geometric Ultrasound Localization Microscopy
Medical Image Computing and Computer Assisted Intervention – MICCAI 2023Pages 217–227https://doi.org/10.1007/978-3-031-43999-5_21AbstractContrast-Enhanced Ultra-Sound (CEUS) has become a viable method for non-invasive, dynamic visualization in medical diagnostics, yet Ultrasound Localization Microscopy (ULM) has enabled a revolutionary breakthrough by offering ten times higher ...
- ArticleOctober 2023
LUCYD: A Feature-Driven Richardson-Lucy Deconvolution Network
Medical Image Computing and Computer Assisted Intervention – MICCAI 2023Pages 656–665https://doi.org/10.1007/978-3-031-43993-3_63AbstractThe process of acquiring microscopic images in life sciences often results in image degradation and corruption, characterised by the presence of noise and blur, which poses significant challenges in accurately analysing and interpreting the ...
- rapid-communicationAugust 2023
An optodigital system for visualizing the leaf epidermal surface using embedded speckle SIM: A 3D non-destructive approach
Computers and Electronics in Agriculture (COEA), Volume 211, Issue Chttps://doi.org/10.1016/j.compag.2023.107962Graphical abstractOverview of the proposed method for plant leaf epidermal imaging.
Here we propose and demonstrate the use of embedded speckle structured illumination microscopy for the non-destructive evaluation and 3D reconstruction of the plant ...
Highlights- An optodigital system for 3D visualization of plant leaf epidermis.
- Optically sectioned images of leaf epidermis with high axial resolution.
- An algorithm based on height segmentation for necrosis detection is presented.
- ...
Intricate characterisation of the leaf epidermal surface is of utmost importance in agricultural crop management. The epidermal surface serves as a plant's outermost interface with the environment and is responsible for several physiological ...
- research-articleFebruary 2023
SECS: An effective CNN joint construction strategy for breast cancer histopathological image classification
Journal of King Saud University - Computer and Information Sciences (JKSUCIS), Volume 35, Issue 2Pages 810–820https://doi.org/10.1016/j.jksuci.2023.01.017AbstractBreast cancer is one of the most prevalent cancers in women. Reliable pathology identification can help histopathologists make accurate diagnosis of breast cancer but require specialized histopathological knowledge and a significant ...
- ArticleSeptember 2022
Adversarial Stain Transfer to Study the Effect of Color Variation on Cell Instance Segmentation
Medical Optical Imaging and Virtual Microscopy Image AnalysisPages 105–114https://doi.org/10.1007/978-3-031-16961-8_11AbstractStain color variation in histological images, caused by a variety of factors, is a challenge not only for the visual diagnosis of pathologists but also for cell segmentation algorithms. To eliminate the color variation, many stain normalization ...
- ArticleSeptember 2022
ChrSNet: Chromosome Straightening Using Self-attention Guided Networks
Medical Image Computing and Computer Assisted Intervention – MICCAI 2022Pages 119–128https://doi.org/10.1007/978-3-031-16440-8_12AbstractKaryotyping is an important procedure to assess the possible existence of chromosomal abnormalities. However, because of the non-rigid nature, chromosomes are usually heavily curved in microscopic images and such deformed shapes hinder the ...
- ArticleSeptember 2022
Unsupervised Cross-Domain Feature Extraction for Single Blood Cell Image Classification
Medical Image Computing and Computer Assisted Intervention – MICCAI 2022Pages 739–748https://doi.org/10.1007/978-3-031-16437-8_71AbstractDiagnosing hematological malignancies requires identification and classification of white blood cells in peripheral blood smears. Domain shifts caused by different lab procedures, staining, illumination, and microscope settings hamper the re-...
- ArticleSeptember 2022
Super-Focus: Domain Adaptation for Embryo Imaging via Self-supervised Focal Plane Regression
- Chloe He,
- Céline Jacques,
- Jérôme Chambost,
- Jonas Malmsten,
- Koen Wouters,
- Thomas Fréour,
- Nikica Zaninovic,
- Cristina Hickman,
- Francisco Vasconcelos
Medical Image Computing and Computer Assisted Intervention – MICCAI 2022Pages 732–742https://doi.org/10.1007/978-3-031-16434-7_70AbstractIn recent years, the field of embryo imaging has seen an influx of work using machine learning. These works take advantage of large microscopy datasets collected by fertility clinics as routine practice through relatively standardised imaging ...
- ArticleJuly 2022
A U-Net Based Progressive GAN for Microscopic Image Augmentation
AbstractDealing with limited medical imagery data by deep neural networks is of a great concern. Obtaining large-scale labelled images requires expertise, is laborious and time consuming, and remains a challenge in medical applications. In this paper, we ...
- research-articleJune 2022
Elastic 3D–2D Image Registration
Journal of Mathematical Imaging and Vision (JMIV), Volume 64, Issue 5Pages 443–462https://doi.org/10.1007/s10851-022-01083-1AbstractWe propose a method to nonrigidly align a three-dimensional (3D) volumetric image with a two-dimensional (2D) planar image representing a projection of the deformed volume. The application in mind comes from biological studies in which 2D ...
- ArticleOctober 2021
Noise2Stack: Improving Image Restoration by Learning from Volumetric Data
- Mikhail Papkov,
- Kenny Roberts,
- Lee Ann Madissoon,
- Jarrod Shilts,
- Omer Bayraktar,
- Dmytro Fishman,
- Kaupo Palo,
- Leopold Parts
Machine Learning for Medical Image ReconstructionPages 99–108https://doi.org/10.1007/978-3-030-88552-6_10AbstractBiomedical images are noisy. The imaging equipment itself has physical limitations, and the consequent experimental trade-offs between signal-to-noise ratio, acquisition speed, and imaging depth exacerbate the problem. Denoising is, therefore, an ...
- research-articleSeptember 2021
Building robust pathology image analyses with uncertainty quantification
Computer Methods and Programs in Biomedicine (CBIO), Volume 208, Issue Chttps://doi.org/10.1016/j.cmpb.2021.106291Highlights- Parameter sensitivity analysis (SA) and Uncertainty Quantification (UQ) was evaluated in Pathology image analysis workflows.
Background and Objective:Computerized pathology image analysis is an important tool in research and clinical settings, which enables quantitative tissue characterization and can assist a pathologist’s evaluation. The aim ...