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November 2024
Identification of immunosenescence of unconventional T cells in hepatocellular carcinoma
Computational Biology and Chemistry (COBC), Volume 112, Issue Chttps://doi.org/10.1016/j.compbiolchem.2024.108148
Abstract
Accumulation of senescent cells is a recognized feature in hepatocellular carcinoma (HCC), but their specific types and prognostic implications remain under investigation. This study aimed to delineate senescent cell types and their senescent ...
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Unconventional T cells including NKT cells and γδT cells showed a predominant senescent signature in HCC.
Senescent unconventional T cells in HCC might weaken the immune system against tumor development and lead to a worse overall ...
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