Nothing Special   »   [go: up one dir, main page]

skip to main content
10.1145/1785481.1785583acmconferencesArticle/Chapter ViewAbstractPublication PagesglsvlsiConference Proceedingsconference-collections
research-article

A novel droplet routing algorithm for digital microfluidic biochips

Published: 16 May 2010 Publication History

Abstract

One of the recent areas of research interest is the use of microfluidics for building up biochips, the digital microfluidic biochips (DMFB). This paper deals with a challenging problem related to the design of DMFB. Specifically the design problem considered is related to high performance droplet routing, where each droplet has single source location and single target location. The objectives are (i) minimizing the number of electrodes used in the DMFB, and (ii) minimizing the total routing time of all the droplets or arrival time of a droplet that is the last to arrive at its target(latest arrival time). We propose a simple algorithm for concurrent path allocation to multiple droplets, based on the Soukup's routing algorithm [22], together with the use of stalling, and possible detouring of droplets in cases of contentions. Selection of the droplets is based on their respective source to target Manhattan paths. The empirical results are quite encouraging.

References

[1]
Boahringer. K. F. "Modeling and controlling parallel tasks in droplet based microfluidic systems". IEEE Transactions Computer-Aided Design of Integrated Circuits and Systems, 25(2):334 -- 344, February 2006.
[2]
Cho Minsik and Pan. David Z. "A high-performance droplet routing algorithm for digital microfluidic biochips." IEEE Transactions Computer-Aided Design of Integrated Circuits and Systems, 27(10):406--419, October 2008.
[3]
Akella S. Griffith E. J. and Goldberg. M. K. "Performance characterization of a reconfigurable planar-array digital microfluidic system." IEEE Transactions Computer-Aided Design of Integrated Circuits and Systems, 25(10):340--352,February 2006.
[4]
Hwang William, Su Fei and Chakrabarty K. "Droplet routing in the synthesis of digital microfluidic biochips." In Proceedings of Design Automation and Test in Europe, 2006.
[5]
Zeng X., Liu L.Wu, J,Yue. R. "Droplets Actuating Chip Based On EWOD". Springer-Verlag, 2007.
[6]
Mukherjee. T. "Design automation issues for biofluidic microchips." In Proceedings of International Conference on Computer Aided Design, page 463 -- 470, November 2005.
[7]
Pollack M.G, Paik P, Pamula V.K and Chakrabarty K. "Coplanar digital microfluidics using standard printed circuit board Processes". In Proceedings of in MicroTAS, 2005.
[8]
Yang C.L, Yuh P.H. and Chang. Y.W. "Bioroute: A network flow based routing algorithm for digital microfluidic biochips." In Proceedings of IEEE/ACM International Conference of Computer Aided Design, pages 752--757, 2007.
[9]
Yang Chia-Lin,Chang Yao-Wen,Yuh Ping-Hung, Sapatnekar S. "A progressive-ilp based routing algorithm for Cross referencing biochips." In Proceedings of Design Automation Conference, pages 284 -- 289, June 2008.
[10]
Ren H., Paik P, Pamula V. K, Fair R. B., Srinivasan V. and Pollack. M.G. "Electrowetting-based on-chip sample processing for integrated microfluidics." In Proceedings of IEEE International Electron Devices Meeting (IEDM), pages 32.5.1--32.5.4, 2003.
[11]
Tailor T.D., Ivan V., Evans R. D., Griffin P. B., Srinivasan,V.Pamula V. K., Pollack M. G. Fair R. B., Khlystov A. and Zhou J. "Chemical and biological applications of digital- microfluidic devices." IEEE Design and Test for Computers, 24:10--24, 2007.
[12]
Sarrafzadeh M. and Wong. C. K. "An Introduction to VLSI Physical Design". McGraw Hill, 1996.
[13]
Sherwani. Naveed A. "Algorithm for VLSI Physical Design Automation."Kluwer Academic Publishers, Boston, 1999.
[14]
Stallings William "Data and Computer Communication"- Prentice Hall of India Pvt. Ltd, New Delhi,India,2004.
[15]
Su Fei and Chakrabarty K. "Architectural-Level synthesis of digital microfluidics-based biochips". In Proceedings of IEEE International Conference on CAD, pages 223--228,2004
[16]
Su F, Xu T., Hwang W. and Chakrabarty. K. "Automated design of pin-constrained digital microfluidic biochips under droplet-interference constraints." ACM Journal on Emerging Technologies in Computing Systems, 3(14), 2007.
[17]
Rivest Robert L., Cormen Thomas H, Leiserson. Charles E. "Introduction to Algorithms". MIT, 1990.
[18]
Xu T. and Chakrabarty. K. "Droplet-trace-based array partitioning and a pin assignment algorithm for the automated design of digital microfluidic biochips." In Proceedings of IEEE/ACM International Conference on Hardware/Software Codesign and System Synthesis, pages 112--117, 2006.
[19]
Xu T. and Chakrabarty. K. "A cross-referencing-based droplet manipulation method for high-throughput and pinconstrained digital microfluidic arrays." In Proceedings of Design Automation and Test in Europe, pages 552 -- 557, April 2007.
[20]
Xu T. and Chakrabarty. K. "Integrated droplet routing in the synthesis of microfluidic biochips." In Proceedings of Design Automation Conference, pages 948 -- 953, 2007.
[21]
Paik Philip. Y., Pamula Vamsee K. and Chakrabarty K., "Adaptive Cooling of Integrated Circuits Using Digital Microfluidics" IEEE Transactions on Very Large Scale Integration(VLSI) Systems, vol. 16, no. 4, April 2008.
[22]
Soukup J, "Fast Maze Router" Proceedings of the 15th ACM IEEE Design Automation Conference, Pages 100--102,1978

Cited By

View all
  • (2023)Compiling Functions onto Digital MicrofluidicsProceedings of the 21st ACM/IEEE International Symposium on Code Generation and Optimization10.1145/3579990.3580023(136-148)Online publication date: 17-Feb-2023
  • (2023)A Flooding-Based Droplet Routing Protocol for Digital Microfluidic BiochipJournal of Circuits, Systems and Computers10.1142/S021812662350302432:17Online publication date: 30-May-2023
  • (2023)A bidirectional droplet routing in digital microfluidics biochipMicroprocessors & Microsystems10.1016/j.micpro.2023.10477498:COnline publication date: 1-Apr-2023
  • Show More Cited By

Recommendations

Comments

Please enable JavaScript to view thecomments powered by Disqus.

Information & Contributors

Information

Published In

cover image ACM Conferences
GLSVLSI '10: Proceedings of the 20th symposium on Great lakes symposium on VLSI
May 2010
502 pages
ISBN:9781450300124
DOI:10.1145/1785481
Permission to make digital or hard copies of all or part of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for components of this work owned by others than ACM must be honored. Abstracting with credit is permitted. To copy otherwise, or republish, to post on servers or to redistribute to lists, requires prior specific permission and/or a fee. Request permissions from [email protected]

Sponsors

In-Cooperation

  • IEEE CEDA
  • IEEE CASS

Publisher

Association for Computing Machinery

New York, NY, United States

Publication History

Published: 16 May 2010

Permissions

Request permissions for this article.

Check for updates

Author Tags

  1. biochips
  2. layout
  3. microfluidics
  4. placement and routing

Qualifiers

  • Research-article

Conference

GLSVLSI '10
Sponsor:
GLSVLSI '10: Great Lakes Symposium on VLSI 2010
May 16 - 18, 2010
Rhode Island, Providence, USA

Acceptance Rates

Overall Acceptance Rate 312 of 1,156 submissions, 27%

Contributors

Other Metrics

Bibliometrics & Citations

Bibliometrics

Article Metrics

  • Downloads (Last 12 months)9
  • Downloads (Last 6 weeks)0
Reflects downloads up to 27 Nov 2024

Other Metrics

Citations

Cited By

View all
  • (2023)Compiling Functions onto Digital MicrofluidicsProceedings of the 21st ACM/IEEE International Symposium on Code Generation and Optimization10.1145/3579990.3580023(136-148)Online publication date: 17-Feb-2023
  • (2023)A Flooding-Based Droplet Routing Protocol for Digital Microfluidic BiochipJournal of Circuits, Systems and Computers10.1142/S021812662350302432:17Online publication date: 30-May-2023
  • (2023)A bidirectional droplet routing in digital microfluidics biochipMicroprocessors & Microsystems10.1016/j.micpro.2023.10477498:COnline publication date: 1-Apr-2023
  • (2022)Droplet Routing Based on Double Deep Q-Network Algorithm for Digital Microfluidic BiochipsJournal of Circuits, Systems and Computers10.1142/S021812662250299131:17Online publication date: 23-Jul-2022
  • (2022)An evolutionary algorithm with indirect representation for droplet routing in digital microfluidic biochipsEngineering Applications of Artificial Intelligence10.1016/j.engappai.2022.105305115:COnline publication date: 1-Oct-2022
  • (2020)A performance-optimizing compiler for cyber-physical digital microfluidic biochipsProceedings of the 18th ACM/IEEE International Symposium on Code Generation and Optimization10.1145/3368826.3377925(171-184)Online publication date: 22-Feb-2020
  • (2020)Reinforcement Learning based Droplet Routing Algorithm for Digital Microfluidic Biochips2020 24th International Symposium on VLSI Design and Test (VDAT)10.1109/VDAT50263.2020.9190306(1-6)Online publication date: Jul-2020
  • (2020)Virtual Droplet Routing Algorithm for Digital Microfluidic Biochips2020 24th International Symposium on VLSI Design and Test (VDAT)10.1109/VDAT50263.2020.9190214(1-6)Online publication date: Jul-2020
  • (2019)PuddleProceedings of the Twenty-Fourth International Conference on Architectural Support for Programming Languages and Operating Systems10.1145/3297858.3304027(183-197)Online publication date: 4-Apr-2019
  • (2019)A Space Efficient Greedy Droplet Routing for Digital Microfluidics BiochipVLSI Design and Test10.1007/978-981-32-9767-8_9(102-114)Online publication date: 18-Aug-2019
  • Show More Cited By

View Options

Login options

View options

PDF

View or Download as a PDF file.

PDF

eReader

View online with eReader.

eReader

Media

Figures

Other

Tables

Share

Share

Share this Publication link

Share on social media