Author: Schumacher, Fredrick R : Search

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November 2024
Small-group originating model: Optimized individual-level GWAS simulation featured by SLiM and using open-access data
- Zuxi Cui,
- Fredrick R. Schumacher
Computational Biology and Chemistry (COBC), Volume 112, Issue Chttps://doi.org/10.1016/j.compbiolchem.2024.108147
Abstract
The development of analytical methods for Genome-wide Association Studies (GWAS) has outpaced the evolution of simulation techniques and pipelines. This disparity underscores the importance of innovative simulation methods that can keep pace with ...
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Introduced the SGO model using SLiM for simulating individual-level GWAS data, addressing the need of large-scale simulations (50,000+ individuals).
Demonstrated SGO's superior efficiency over HapGen for samples >13,000, enabling ...
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