This study aimed to use CiteSpace software to conduct a bibliometric analysis of published on the nursing informatics competencies from 2000 to 2020. Data were obtained from the China National Knowledge Infrastructure and Wanfang Database. Co-occurrence analysis, collaboration analysis and Co-Words Analysis of keywords were conducted by using CiteSpace5.7 R2 software. A total of 496 publications were obtained. The number of publications generally increased over the investigated period. The most publications were from colleges and universities. ‘Influencing factor’, ‘nursing informatics competencies’, and ‘nursing education’ were the hotspots recently. The study may be helpful for researchers in identifying the research status quo, trend and development of nursing informatics competencies in China in the future.