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An improved artificial bee colony algorithm for 3D protein structure prediction

Published: 21 April 2017 Publication History

Abstract

One of the key problems in the field of bioinformatics is protein structure prediction. The thermodynamic hypothesis demonstrates that protein's energy is the lowest in nature state. So protein's structure can be gotten directly by protein sequence's free-energy. In this paper, an improved algorithm based on three-dimensional AB off-lattice model to improve local search and global optimization ability of artificial bee colony algorithm has been presented. The simulation experiment shows that it can effectively search the lowest free-energy in the condition of keeping high accuracy. The experimental results indicate that the minimum energy from the improved artificial bee colony algorithm is better than other similar algorithms, and with the increase of protein sequence's length, this algorithm has better performance.

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Cited By

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  • (2023)Composing Multiple Online Exams: The Bees Algorithm SolutionApplied Sciences10.3390/app13231271013:23(12710)Online publication date: 27-Nov-2023
  • (2018)A Novel Approach to Protein Folding Prediction based on Long Short-Term Memory Networks: A Preliminary Investigation and Analysis2018 International Joint Conference on Neural Networks (IJCNN)10.1109/IJCNN.2018.8489514(1-8)Online publication date: Jul-2018

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    ICBEA '17: Proceedings of the 2017 International Conference on Biometrics Engineering and Application
    April 2017
    61 pages
    ISBN:9781450348713
    DOI:10.1145/3077829
    Permission to make digital or hard copies of all or part of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for components of this work owned by others than ACM must be honored. Abstracting with credit is permitted. To copy otherwise, or republish, to post on servers or to redistribute to lists, requires prior specific permission and/or a fee. Request permissions from [email protected]

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    New York, NY, United States

    Publication History

    Published: 21 April 2017

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    Author Tags

    1. AB off-lattice model
    2. artificial bee colony algorithm
    3. protein structure prediction

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    View all
    • (2023)Composing Multiple Online Exams: The Bees Algorithm SolutionApplied Sciences10.3390/app13231271013:23(12710)Online publication date: 27-Nov-2023
    • (2018)A Novel Approach to Protein Folding Prediction based on Long Short-Term Memory Networks: A Preliminary Investigation and Analysis2018 International Joint Conference on Neural Networks (IJCNN)10.1109/IJCNN.2018.8489514(1-8)Online publication date: Jul-2018

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