Abstract
DURING certain normal immunisation schedules, suppressor cells are generated and act in suppressing the expression of delayed hypersensitivity reactions1,2. The suppression is immunologically specific and is dependent on living cells. We have suggested that the suppressor cells were B cells because they are depleted when 300 mg kg−1 cyclophosphamide (CY) is given 3 d before sensitisation3–5.
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References
Katz, S. I., Parker, D., Sommer, G., and Turk, J. L., Nature, 248, 612 (1974).
Neta, R., and Salvin, S. B., Cell. Immun., 9, 242 (1973).
Turk, J. L., and Poulter, L. W., Clin. exp. Immun., 10, 285 (1972).
Poulter, L. W., and Turk, J. L., Nature new Biol., 238, 17 (1972).
Turk, J. L., Parker, D., and Poulter, L. W., Immunology, 23, 493 (1972).
Blazkovec, A. A., Sorkin, E., and Turk, J. L., Int. Arch. Allergy, 27, 289 (1965).
Campbell, P. A., and Grey, H. M., Cell. Immun., 5, 171 (1972).
Russell, A. S., Liburd, E. M., and Diener, E., Nature, 249, 43 (1974).
Gorcynski, R., J. Immun., 112, 1826 (1974).
Kerckhaert, J. A. M., van den Berg, G. J., and Willers, J. M. N., Annales d' Immunologie, 125 C, 415 (1974).
Cantor, H., and Asofsky, R., J. exp. Med., 135, 764 (1972).
Gershon, R. K., Liebhaber, S., and Ryn, S., Immunology, 26, 909 (1974).
Zembala, M., and Asherson, G. L., Nature, 244, 227 (1973).
Taussig, M. J., Nature, 248, 236 (1974).
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KATZ, S., PARKER, D. & TURK, J. B-cell suppression of delayed hypersensitivity reactions. Nature 251, 550–551 (1974). https://doi.org/10.1038/251550a0
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DOI: https://doi.org/10.1038/251550a0