Single-molecule detection in solution: a new tool for analytical chemistry

Abstract

Single-molecule detection (SMD) is becoming more and more popular in the scientific community and is on the threshold to become a technique for laboratory use. Therefore, conceivable applications as well as optimized conditions for SMD will be discussed. To point out the possibilities of SMD, the signal-to-background ratio and the detection efficiency, in combination with the probability of misclassification, will be contemplated.

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1. Universität Siegen, Adolf-Reichwein-Strasse 2, 57068 Siegen, Germany, , , , , , DE

   C. Zander

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1. C. Zander
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Received: 6 October 1999 / Revised: 13 December 1999 / Accepted: 18 December 1999

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Zander, C. Single-molecule detection in solution: a new tool for analytical chemistry. Fresenius J Anal Chem 366, 745–751 (2000). https://doi.org/10.1007/s002160051568

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• Issue Date: March 2000

• DOI: https://doi.org/10.1007/s002160051568

Keywords

• Analytical Chemistry
• Scientific Community
• Detection Efficiency
• Conceivable Application