Abstract
An existing multicompartmental model for simulating the exchange processes during hemodialysis has been modified and extended. Especially new aspects of the control of volumes and electrolytes have been integrated. The model contains compartments for the following subatances: Na+, K+, Cl−, HCO −3 , CO2, H+, urea, creatinine and vitamine B12. Volumes are calculated for blood-plasma, erythrocytes, interstitial fluid and intracellular space. Since few parameters of the system are not exactly known, they can be fitted for achieving good agreement between simulated and measured data. A first evaluation of the model was performed by using the data measured from 8 hemodialysis patients.
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© 1994 Springer-Verlag
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Scharfetter, H., Hutten, H. (1994). Computer model for simulating control of the water and electrolyte state in the human body. In: Henry, J., Yvon, JP. (eds) System Modelling and Optimization. Lecture Notes in Control and Information Sciences, vol 197. Springer, Berlin, Heidelberg. https://doi.org/10.1007/BFb0035489
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DOI: https://doi.org/10.1007/BFb0035489
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