Intralobular heterogeneity of perisinusoidal stellate cells in porcine liver

• Bhunchet E, Wake K (1992) The role of mesenchymal cell populations in the porcine serum-induced rat liver fibrosis. Hepatology 16:1452–1473

  Google Scholar 

• Blomhoff R, Wake K (1991) The perisinusoidal stellate cells of the liver: important roles in retinol metabolism and fibrosis. FASEB J 5:271–277

  Google Scholar 

• Blomhoff R, Berg T, Norum KR (1988) Transfer of retinol parenchymal to stellate cells in liver is mediated by retinol-binding protein. Proc Natl Acad Sci USA 85:3455–3458

  Google Scholar 

• Bouwens L, Baekeland M, Dezanger R, Wisse e (1986) Quantitations, tissue distribution and proliferation kinetics of Kupffer cells in normal rat liver. Hepatology 6:718–722

  Google Scholar 

• Decker K, Dieter P, Henninger HP, Eyhorn S, Birmelin M (1986) The arachidonoids released by rat Kupffer cells in response to phagocytotic stimuli. In: Kirn A, Wisse E, Knook DL (eds) Cells of the hepatic sinusoid, vol 1. Kupffer Cell Foundation, Rijswijk, The Netherlands, pp 65–70

  Google Scholar 

• Ekataksin W, Wake K (1987) A study on portal microcirculation of hepatic lobule — the inconsistency of Rappaport's acinar concept (abstract). Acta Anat Nippon 62:486

  Google Scholar 

• Ekataksin W, Wake K (1991) Liver units in three dimensions: I. Organization of argyrophilic connective tissue skeleton in porcine liver with particular reference to the “compound hepatic lobule”. Am J Anat 191:113–153

  Google Scholar 

• Geerts A, Lazou J-M, De Bleser P, Wisse E (1991) Tissue distribution, quantitation and proliferation kinetics of fat-storing cells in carbon tetachloride0injured rat liver. Hepatology 13:1193–1202

  Google Scholar 

• Gressner AM (1991) Major topics of fibrosis research: 1990 update. In: Wisse E, Knook DL, McCuskey RS (eds) Cells of the hepatic sinusoid, vol 3. Kupffer Cell foundation, Leiden, The Netherlands, pp 136–144

  Google Scholar 

• Gressner AM, Lahme B (1991) Inhibitory actions of hepatocyte plasma membranes on proliferation, protein- and proteoglycan synthesis of cultured rat fat storing cells. In: Wisse E, Knook DL, McCuskey RS (eds) Cells of the hepatic sinusoid, vol 3. Kupffer Cell Foundation, Leiden, The Netherlands, pp 237–241

  Google Scholar 

• Gumucio JJ (1989) Hepatocyte heterogeneity: the coming of age from the description of a biological curiosity to a partial under-standing of its physiological meaning and regulation. Hepatology 9:154–160

  Google Scholar 

• Hosemann W, Teutsch HE, Sasse D (1979) Identification of G6PDH-active sinusoidal cells as Kupffer cells in the rat liver. Cell Tissue Res 196:237–247

  Google Scholar 

• Ito T (1973) Recent advances in the study on the fine structure of the hepatic sinusoidal wall: a review. Gunma Rep Med Sci 6:119–163

  Google Scholar 

• Jungermann K (1989) Zonal signal heterogeneity and induction of hepatocyte heterogeneity. In: Thurman RG, Kaufman FC, Jungermann K (eds) Regulation of hepatic metabolism: intra-and intercellular compartmentation. Plenum Press, New York London, pp 445–469

  Google Scholar 

• Kaneda K, Wake K (1983) Distribution and morphological characteristics of the pit cells in the liver of the rat. Cell Tissue Res 233:485–505

  Google Scholar 

• Kawada N, Klein H, Decker K (1992) Eicosanoid-mediated contractility of hepatic stellate cells. Biochem J 285:367–371

  Google Scholar 

• Knook DL, Blaner WS, Brouwer A, Hendriks HFJ (1989) The role of non-parenchymal cells in liver retinoid metabolism. In: Wisse E, Knook DL, Decker K (eds) Cells of the hepatic sinusoid, vol 2. Kupffer Cell Foundation, Rijswijk, The Netherlands, pp 16–19

  Google Scholar 

• Kupffer C von (1876) Ueber Sternzellen in der Leber Briefliche Mitteilung an Prof. Waldeyer. Arch Mikrosk Anat 12:353–358

  Google Scholar 

• Lamers WH, Hilberts A, Furt E, Smith J, Jonges GN, Noorden CJFV, Janzen JWG, Charles R, Moorman AFM (1989) Hepatic enzymic zonation: a reevaluation of the concept of the liver acinus. Hepatology 10:72–76

  Google Scholar 

• Matsumoto E, Hirosawa K (1983) Some observations on the structure of Suncus liver with special reference to the viatmin A-storing cell. Am J Anat 167:193–204

  Google Scholar 

• Matsumoto T, Komori R, Magara T, Ui T, Kawakami M, Tokuda T, Takasaki S, Hayashi H, Jo K, Hano H, Fujino H, Tanaka H (1979) A study of the normal structure of the human liver, with special reference to its angioarchitecture. Jikeikai Med J 26:1–40

  Google Scholar 

• McCuskey RS (1988) Hepatic microcirculation. In: Bioulac-Sage P, Balabaud C (eds) Sinusoids in human liver. Health and disease. Kupffer cell Foundation, Rijswijk, The Netherlands, pp 151–164

  Google Scholar 

• Moriwaki HJ, Blaner WS, Piatedosi R, Goodman DeWS (1988) Effects of dietary retinoid and tringlyceride on the lipid composition of rat liver stellate cell lipid droplets. J Lipid Res 29:1523–1534

  Google Scholar 

• Quistorff B, Rømert P (1989) High zone-selectivity of cell permeabilization following digitonin-pulse perfusion of rat liver. A re-interpretation of the microcirculatory zones. Histochemistry 92:487–498

  Google Scholar 

• Ramadori G (1991) The stellate cell (Ito cell, fat-storing cell, lipocyte, perisinusoidal cell) of the liver. New insights into pathophysiology of an intriguing cell. Virchows Arch [B] 61:147–158

  Google Scholar 

• Ramadori G, VeitT, Schwogler S, Dienes HP, Knittel T, Rieder H, Meyer zum Büschenfelde K-H (1990) Expression of the gene of the α-smooth muscle actin isoform in rat liver and in rat fat-storing (ITO) cells. Virchows Arch [B] 59:349–357

  Google Scholar 

• Reid LM, Fiorino AS, Sigal SH, Brill S, Holst PA (1992) Extracellular matrix gradients in the space of Disse: Relevance to liver biology. Hepatology 15:1198–1203

  Google Scholar 

• Sasse D (1986) Liver structure and innervation. In: Thurman RG, Kauffman FC, Jungermann K (eds) Regulation of hepatic metabolism: intra- and intercellular compartmentation. Plenum Press, New York, pp 3–25

  Google Scholar 

• Sleyster EC, Knook DL (1982) Relation between localization and function of rat liver Kupffer cells. Lab Invest 47:484–490

  Google Scholar 

• Takahashi-Iwanaga H, Fujita T (1986) Application of an NaOH maceration method to a scanning electron microscopic observation of Ito cells in the rat liver. Arch Histol Jpn 49:349–357

  Google Scholar 

• Te Koppele JM, Thurman RG (1990) Phagocytosis by Kupffer cells predominates in pericentral regions of the liver lobule. Am J Physiol G814–G821

• Teutsch HF (1984) Sex-specific regionality of liver metabolism during starvation with special reference to the heterogeneity of the lobular periphery. Histochemistry 81:87–92

  Google Scholar 

• Teutsch HF (1988) Regionality of glucose-6-Pase hydrolysis in the liver lobule of the rat: metabolic heterogeneity of “poral” and “septal” sinusoids. Hepatology 8:311–317

  Google Scholar 

• Wake K (1971) “Sternzellen” in the liver: perisinusoidal cells with special reference to storage of vitamin A. Am J Anat 132:429–462

  Google Scholar 

• Wake K (1974) Development of vitamin A-rich lipid droplets in multivesicular bodies of rat liver stellate cells. J Cell Biol 63:683–691

  Google Scholar 

• Wake K (1980) Perisinusoidal stellate cells (fat-storing cells, interstitial cells, lipocyres), their related structure in and around the liver sinusoids, and vitamin A-storing cells in extrahepatic organs. Int Rev Cytol 66:303–353

  Google Scholar 

• Wake K (1986) Vitamin A-storing cells. Electron-Microscopy 21:74–80 (in Japanese)

  Google Scholar 

• Wake K (1988) Liver perivascular cells revealed by gold-and silverimpregnation methods and electron microscopy. In: Motta PM (ed) Biopathology of the liver. An ultrastructural approach. Kluwer, Dordrecht Boston London, pp 23–36

  Google Scholar 

• Wake K (1989) Rapid Golgi method contributes notably to the study of liver sinusoidal cells. In: Wisse E, Knook DL, Decker K (eds) Cells of the hepatic sinusoid, vol 2. Kupffer Cell Foundation, Rijswijk, The Netherlands, pp 449–450

  Google Scholar 

• Wake K, Motomatsu K, Senoo H, Masuda A, Adachi E (1986) Improved Kupffer's gold chloride method for demonstrating the stellate cells storing retinol (vitamin A) in the liver and extrahepatic organs of vertebrates. Stain Technol 61:193–200

  Google Scholar 

• Wake K, Motomatsu K, Dan C, Kaneda K (1988) Three-dimensional structure of endothelial cells in hepatic sinusoids of the rat as revealed by the Golgi method. Cell Tissue Res 253:563–571

  Google Scholar 

• Wake K, Decker K, Kirn A, Knook DL, McCuskey RS, Bouwens L, Wisse E (1989) Cell biology and kinetics of Kupffer cells in the liver. Int Rev Cytol 118:173–229

  Google Scholar 

• Wake K, Motomatsu K, Ekataksin W (1991) Postnatal development of the perinusoidal stellate cells in the rat liver. In: Wisse E, Knook DL, McCuskey RS (eds) Cells of the hepatic sinusoid, vol 3. Kupffer cell Foundation, Leiden, The Netherlands, pp 269–275

  Google Scholar 

• Wake K, Kishiye T, Yamamoto H, Kaneda K, Sato C (1992) Sinusoidal cell function life under the microscope. In: Gressner AM, Ramadori G (eds) Molecular and cell biology of liver fibrogenesis. Falk Foundation, Freiburg, pp 45–51

  Google Scholar 

• Wake K, Kishiye T, Yamamoto H, Bhunchet E, Sakamoto Y, Sato T (1993) Kupffer cells modulate the configuration of perisinusoidal stellate cells. In: Wisse E, Knook DL (eds) Cells of the hepatic sinusoid, vol 3. Kupffer Cell Foundation, Leiden, The Netherlands (in press)

  Google Scholar 

• Wisse E, Zanger RB de, Charels K, Van Der Smissen P, McCuskey RS (1985) The liver sieve: considerations concerning the structure and function of endothelial fenestrae, the sinusoidal wall and the space of Disse. Hepatology 5:683–692

  Google Scholar 

• Wunsche A (1981) Lupenanatomie der klassischen Leberläppchen des Schweines. Z Vet Med [Anat Histol Embryol] 10:342–350

  Google Scholar 

• Yokoi Y, Namihisa T, Kuroda H, Komatsu I, Miyazaki A, Watanabe S, Usui K (1984) Immunocytochemical detection of desmin in fat-storing cells (Ito cells). Hepatology 5:683–692

  Google Scholar 

• Zajicek G, Ariel I, Arber N (1988) The streaming liver. III. Littoral cells accompany the streaming hepatocyte. Liver 8:213–218

  Google Scholar 

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