Abstract
The records of 43 consecutive patients (51 eyes) with the ocular ischemic syndrome (ocular symptoms and signs attributable to severe carotid artery obstruction) were studied in a retrospective fashion. Men comprised 67% of the group and the mean age at presentation was 64.5 years. In the anterior segment, neovascularization of the iris was observed in 66% of eyes and iritis was noted in 18%. Posterior segment signs included narrowed retinal arteries and dilated, but not tortuous, retinal veins. Mid-peripheral retinal hemorrhages were seen in 80% of eyes, posterior segment neovascularization was observed in 37%, and a cherry red spot was noted in 12%. Fluorescein angiography commonly revealed delayed choroidal and retinal filling, while electroretinography generally demonstrated a reduction in the amplitude of both the a-and b-waves.
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References
Brown GC, Magargal LE, Simeone FA et al. Arterial obstruction and ocular neovascularization. Ophthalmol. 1982; 89: 139–46.
Brown GC. Isolated central retinal artery obstruction in association with ocular neovascularization. Am J Ophthalmol 1983; 96: 110–1.
Brown GC, Magargal LE, Schachat A et al. Neovascular glaucoma. Etiologic considerations. Ophthalmol. 1984; 91: 315–20.
Brown GC. Central retinal vein obstruction. Diagnosis and management. In Reineck RD (ed.), Ophthalmol. Ann. Norwalk: Appleton-Century-Crofts, 1985; 65–97.
Brown GC. Macular edema in association with severe carotid artery obstruction. Am J Ophthalmol 1986; 102: 442–8.
Bullock JD, Falter RT, Downing JE et al. Ischemic ophthalmia secondary to an ophthalmic artery occlusion. Am J Ophthalmol 1972; 74: 486–93.
Carr RE, Siegel JM. Electrophysiologic aspects of several retinal diseases. Am J Ophthalmol 1964; 58: 95–107.
David NJ, Norton EWD, Gass JD et al. Fluorescein angiography in central retinal artery occlusion. Arch Ophthalmol 1967; 77: 619–29.
Hayreh SS, Podhajsky P. Ocular neovascularization with retinal vascular occlusion. II. Occurrence in central and branch retinal artery occlusion. Arch Ophthalmol 1982; 100: 1585–96.
Henkes HE. Electroretinography in circulatory disturbances of the retina. II. The electroretinogram in cases of occlusion of the central retinal artery or of one of its branches. Arch Ophthalmol 1954; 51: 42–53.
Henkind P. Ocular neovascularization. Am J Ophthalmol 1978; 85: 287–301.
Huckman MS, Haas J. Reversed flow through the ophthalmic artery as a cause of rubeosis iridis. Am J Ophthalmol 1972; 74: 1084–9.
Kahn M, Green WR, Knox DL, Miller NR. Ocular features of carotid occlusive disease. Retina 1986; 6: 239–52.
Kearns TP, Hollenhurst RW. Venous-stasis retinopathy of occlusive disease of the carotid artery. Proc Mayo Clin 1963; 38: 304–12.
Kearns TP. Ophthalmology and the carotid artery. Am J Ophthalmol 1979; 88: 714–22.
Kearns TP. Differential diagnosis of central retinal vein obstruction. Ophthalmology 1983; 90: 475–80.
Kearns TP, Sickert RG, Sundt TM. The ocular aspects of bypass surgery of the carotid artery. Proc Mayo Clin 1979; 54: 3–11.
Kobayashi S, Hollenhorst RW, Sundt TM. Retinal arterial pressure before and after surgery for carotid artery stenosis. Stroke 1971; 2: 569–75.
Knox DL. Ischemic ocular inflammation. Am J Ophthalmol 1965; 60: 995–1002.
Magargal LE, Sanborn GE, Zimmerman A. Venous stasis retinopathy associated with embolic obstruction of the central retinal artery. J Clin Neuro-ophthalmol 1982; 2: 113–8.
Michelson PE, Knox DL, Green WR. Ischemic ocular inflammation. A clinicopathologic case report. Arch Ophthalmol 1971; 86: 274–80.
Ridley M, Walker P, Keller A et al. Ocular perfusion in carotid artery disease. Poster presentation, Am Acad Ophthalmol. New Orleans, 1986.
Schlaegel T. Symptoms and signs of uveitis. In Duane TD (ed.) Clinical Ophthalmology, Vol. 4. Hagerstown: Harper & Row, 1983, Chap 32, pp 1–7.
Sturrock GD, Mueller HR. Chronic ocular ischemia. Br J Ophthalmol 1984; 68: 716–23.
Young LHY, Appen RE. Ischemic oculopathy; a manifestation of carotid artery disease. Arch Neurol 1981; 38: 358–61.
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Brown, G.C., Magargal, L.E. The ocular ischemic syndrome. Int Ophthalmol 11, 239–251 (1988). https://doi.org/10.1007/BF00131023
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DOI: https://doi.org/10.1007/BF00131023