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Räumliche Darstellung und Analyse von Nanopartikelverteilungen in vitalen Alveolarmakrophagen in vitro mit der Dunkelfeldmikroskopie

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Bildverarbeitung für die Medizin 2015

Part of the book series: Informatik aktuell ((INFORMAT))

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Kurzfassung

Die räumliche Wechselwirkung von Nanopartikeln mit vitalen alveolären Makrophagen wurde mit der Dunkelfeldmikroskopie, kombiniert mit einer piezogesteuerten Verschiebung der z-Achse und einer Triggerung der Kamerabilder, untersucht. Damit gelang eine räumliche Rekonstruktion von unfixierten motilen Makrophagen bei gleichzeitiger Darstellung der räumlichen und zeitlichen Verteilung der aufgenommenen Nanopartikel. Die räumliche Darstellung der Nanopartikelverteilungen ermöglicht neue Erkenntnisse zur Biokinetik von Nanopartikeln.

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Literaturverzeichnis

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Author information

Authors and Affiliations

  1. Biomedical Imaging Group, Fachbereich Informatik, Fachhochschule Dortmund, Dortmund, Deutschland

    Dominic Swarat, Christian Arens & Hans-Gerd Lipinski

  2. Institute for Lung Health (IBE R&D gGmbH), Münster, Deutschland

    Martin Wiemann

Authors
  1. Dominic Swarat
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  2. Christian Arens
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  3. Martin Wiemann
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  4. Hans-Gerd Lipinski
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Corresponding author

Correspondence to Dominic Swarat .

Editor information

Editors and Affiliations

  1. Lübeck, Germany

    Heinz Handels

  2. RWTH Aachen Inst. Medizinische Informatik, Aachen, Germany

    Thomas Martin Deserno

  3. Heidelberg, Germany

    Hans-Peter Meinzer

  4. Berlin, Berlin, Germany

    Thomas Tolxdorff

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Swarat, D., Arens, C., Wiemann, M., Lipinski, HG. (2015). Räumliche Darstellung und Analyse von Nanopartikelverteilungen in vitalen Alveolarmakrophagen in vitro mit der Dunkelfeldmikroskopie. In: Handels, H., Deserno, T., Meinzer, HP., Tolxdorff, T. (eds) Bildverarbeitung für die Medizin 2015. Informatik aktuell. Springer Vieweg, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-46224-9_44

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  • DOI: https://doi.org/10.1007/978-3-662-46224-9_44

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  • Publisher Name: Springer Vieweg, Berlin, Heidelberg

  • Print ISBN: 978-3-662-46223-2

  • Online ISBN: 978-3-662-46224-9

  • eBook Packages: Computer Science and Engineering (German Language)

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