Abstract
The toehold and branch migration domain of traditional DNA strand displacement are covalently connected, such a structure cannot be changed during the execution of the circuit, so to some extent it limits the construction of DNA circuits. To solve this problem, we use combinatorial displacement of DNA strands technology where toehold and branch migration domains are located in different strand, these two domains must be firstly linked by hybridization of linking domains that can occur strand displacement reaction, this paper is to design an Inhibit and a XOR based on this principle which is theoretically possible.
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Yurke, B., Turberfield, A.J., Mills, A.P., et al.: A DNA-fuelled Molecular Machine Made of DNA. J. Nature 406(6796), 605–608 (2000)
Frezza, B.M., Cockroft, S.L., Ghadiri, M.R.: Modular Multi-level Circuits from Immobilized DNA-based Logic Gates. J. Journal of the American Chemical Society 129(48), 14875–14879 (2007)
Li, W., Yan, H., Liu, Y., et al.: Three-Input Majority Logic Gate and Multiple Input Logic Circuit Based on DNA Strand Displacement. J. Nano Letters 13(6), 2980–2988 (2013)
Zhang, D., Turberfield, A.J., Yurke, B., et al.: Engineering Entropy-driven Reactions and Networks Catalyzed by DNA. J. Science 318(5853), 1121–1125 (2007)
Sherman, W.B., Seeman, N.C.: A Precisely Controlled DNA Biped Walking Device. J. Nano Letters 4(7), 1203–1207 (2004)
Shin, J.S., Pierce, N.A.: A Synthetic DNA Walker for Molecular Transport. J. Journal of the American Chemical Society 126(35), 10834–10835 (2004)
Gu, H., Chao, J., Xiao, S.J., et al.: A Proximity-Based Programmable DNA Nanoscale Assembly Line. J. Nature 465(7295), 202–205 (2010)
Yan, H., Zhang, X.P., Shen, Z.Y., et al.: A Robust DNA Mechanical Device Controlled by Hybridization Topology. J. Nature 415(6867), 62–65 (2002)
Ding, B.Q., Seeman, N.C.: Operation of a DNA Robot Arm Inserted Into A 2D DNA Crystalline Substrate. J. Science 314(5805), 1583–1585 (2006)
Qian, L.L., Winfree, E.: Scaling Up Digital Circuit Computation with DNA Strand Displacement Cascades. J. Science 332(6034), 1196–1201 (2011)
Zhu, J.B., Zhang, L.B., Wang, E.K., et al.: Four-way junction-driven DNA strand displacement and its application in building majority logic circuit. J. Journal of the American Chemical Society Nano 7(11), 10211–10217 (2013)
Duckett, D.R., Lilley, D.M.: The Three-Way DNA Junction is A Y-Shaped Molecule in which There is No Helix-Helix Stacking. J. The EMBO Journal 9(5), 1659 (1990)
Genot, A.J., Bath, J., Turberfield, A.J.: Combinatorial Displacement of DNA Strands: application to matrix multiplication and weighted sums. J. Angewandte Chemie International Edition 52(4), 1189–1192 (2013)
Chen, X.: Expanding the Rule Set of DNA Circuitry with Associative Toehold Activation. J. Journal of the American Chemical Society. 134(1), 263–271 (2011)
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Zhang, X., Zhang, W., Wang, Y., Cui, G. (2014). Application to Logic Circuits Using Combinatorial Displacement of DNA Strands. In: Pan, L., Păun, G., Pérez-Jiménez, M.J., Song, T. (eds) Bio-Inspired Computing - Theories and Applications. Communications in Computer and Information Science, vol 472. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-45049-9_100
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DOI: https://doi.org/10.1007/978-3-662-45049-9_100
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