Abstract
In this work we present the design, fabrication and characterization of polymer-based soft, stretchable and conductive biointerfaces for achieving both mechanical stimulation of cells and recording of their response. These biointerfaces represent the very first step for investigating potential bio-hybrid tactile sensing approaches. Cells transform mechanical stimuli into biological and biochemical signals (mechanotransduction): modifications on cell mem-brane structure lead to a final change in membrane electric potential. Therefore, an efficient way to quantify cellular response to mechanical stimuli is to evaluate the impedance variation of cells due to externally applied forces.
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Bernardeschi, I., Greco, F., Ciofani, G., Mattoli, V., Mazzolai, B., Beccai, L. (2013). Soft, Stretchable and Conductive Biointerfaces for Bio-hybrid Tactile Sensing Investigation. In: Lepora, N.F., Mura, A., Krapp, H.G., Verschure, P.F.M.J., Prescott, T.J. (eds) Biomimetic and Biohybrid Systems. Living Machines 2013. Lecture Notes in Computer Science(), vol 8064. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-39802-5_32
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DOI: https://doi.org/10.1007/978-3-642-39802-5_32
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-39801-8
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