Nothing Special   »   [go: up one dir, main page]

Skip to main content

Automatic Detection and Identification of Retinal Vessel Junctions in Colour Fundus Photography

  • Conference paper
  • First Online:
Medical Image Understanding and Analysis (MIUA 2017)

Part of the book series: Communications in Computer and Information Science ((CCIS,volume 723))

Included in the following conference series:

Abstract

The quantitative analysis of retinal blood vessels is important for the management of vascular disease and tackling problems such as locating blood clots. Such tasks are hampered by the inability to accurately trace back problems along vessels to the source. This is due to the unresolved challenge of distinguishing automatically between vessel branchings and vessel crossings. In this paper, we present a new technique for tackling this challenging problem by developing a convolutional neural network approach for first locating vessel junctions and then classifying them as either branchings or crossings. We achieve a high accuracy of 94% for junction detection and 88% for classification. Combined with work in segmentation, this method has the potential to facilitate automated localisation of blood clots and other disease symptoms leading to improved management of eye disease through aiding or replacing a clinicians diagnosis.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 109.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 139.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  1. Chollet, F.: Keras (2015). https://github.com/fchollet/keras

  2. Chutatape, O., Zheng, L., Krishnan, S.M.: Retinal blood vessel detection and tracking by matched Gaussian and Kalman filters. In: Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, vol. 6, pp. 3144–3149. IEEE (1998)

    Google Scholar 

  3. Cun, Y.L., Boser, B., Denker, J.S., Howard, R.E., Habbard, W., Jackel, L.D., Henderson, D.: Advances in Neural Information Processing Systems 2, pp. 396–404. Citeseer (1990)

    Google Scholar 

  4. Fukushima, K.: Neocognitron: a self-organizing neural network model for a mechanism of pattern recognition unaffected by shift in position. Biol. Cybern. 36(4), 193–202 (1980)

    Article  MATH  Google Scholar 

  5. Gonzalez, R., Wintz, P.: Digital Image Processing (1977)

    Google Scholar 

  6. He, K., Zhang, X., Ren, S., Sun, J.: Deep residual learning for image recognition. CoRR abs/1512.03385 (2015). http://arxiv.org/abs/1512.03385

  7. Kingma, D.P., Ba, J.: Adam: a method for stochastic optimization. CoRR abs/1412.6980 (2014). http://arxiv.org/abs/1412.6980

  8. Krizhevsky, A.: Learning multiple layers of features from tiny images. https://www.cs.toronto.edu/ kriz/learning-features-2009-TR.pdf

  9. LeCun, Y., Cortes, C.: MNIST handwritten digit database (2010). http://yann.lecun.com/exdb/mnist/

  10. MacGillivray, T., Trucco, E., Cameron, J., Dhillon, B., Houston, J., Van Beek, E.: Retinal imaging as a source of biomarkers for diagnosis, characterization and prognosis of chronic illness or long-term conditions. Br. J. Radiol. 87(1040), 20130832 (2014)

    Article  Google Scholar 

  11. Nair, V., Hinton, G.E.: Rectified linear units improve restricted Boltzmann machines. In: Proceedings of the 27th International Conference on Machine Learning (ICML 2010), pp. 807–814 (2010)

    Google Scholar 

  12. Sonka, M., Hlavac, V., Boyle, R.: Image Processing, Analysis, and Machine Vision. Cengage Learning (2014)

    Google Scholar 

  13. Srivastava, N., Hinton, G., Krizhevsky, A., Sutskever, I., Salakhutdinov, R.: Dropout: a simple way to prevent neural networks from overfitting. J. Mach. Learn. Res. 15(1), 1929–1958 (2014)

    MathSciNet  MATH  Google Scholar 

  14. Staal, J., Abràmoff, M.D., Niemeijer, M., Viergever, M.A., Van Ginneken, B.: Ridge-based vessel segmentation in color images of the retina. IEEE Trans. Med. Imaging 23(4), 501–509 (2004)

    Article  Google Scholar 

  15. Zhao, Y., Rada, L., Chen, K., Harding, S.P., Zheng, Y.: Automated vessel segmentation using infinite perimeter active contour model with hybrid region information with application to retinal images. IEEE Trans. Med. Imaging 34(9), 1797–1807 (2015)

    Article  Google Scholar 

Download references

Acknowledgement

H. Pratt acknowledges PhD funding from Fight for Sight charity. This project is funded in part by the National Institute for Health Research’s i4i Programme. This paper summarises independent research funded by the National Institute for Health Research (NIHR) under its i4i Programme (Grant Reference Number II-LA-0813-20005). The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Harry Pratt .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer International Publishing AG

About this paper

Cite this paper

Pratt, H., Williams, B.M., Ku, J., Coenen, F., Zheng, Y. (2017). Automatic Detection and Identification of Retinal Vessel Junctions in Colour Fundus Photography. In: Valdés Hernández, M., González-Castro, V. (eds) Medical Image Understanding and Analysis. MIUA 2017. Communications in Computer and Information Science, vol 723. Springer, Cham. https://doi.org/10.1007/978-3-319-60964-5_3

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-60964-5_3

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-60963-8

  • Online ISBN: 978-3-319-60964-5

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics