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Evolution of Genes Neighborhood within Reconciled Phylogenies: An Ensemble Approach

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Advances in Bioinformatics and Computational Biology (BSB 2014)

Part of the book series: Lecture Notes in Computer Science ((LNBI,volume 8826))

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Abstract

We consider a recently introduced dynamic programming scheme to compute parsimonious evolutionary scenarios for gene adjacencies. We extend this scheme to sample evolutionary scenarios from the whole solution space under the Boltzmann distribution. We apply our algorithms to a dataset of mammalian gene trees and adjacencies, and observe a significant reduction of the number of syntenic inconsistencies observed in the resulting ancestral gene adjacencies.

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Chauve, C., Ponty, Y., Zanetti, J.P.P. (2014). Evolution of Genes Neighborhood within Reconciled Phylogenies: An Ensemble Approach. In: Campos, S. (eds) Advances in Bioinformatics and Computational Biology. BSB 2014. Lecture Notes in Computer Science(), vol 8826. Springer, Cham. https://doi.org/10.1007/978-3-319-12418-6_7

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  • DOI: https://doi.org/10.1007/978-3-319-12418-6_7

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-12417-9

  • Online ISBN: 978-3-319-12418-6

  • eBook Packages: Computer ScienceComputer Science (R0)

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