Abstract
Understanding the underlying properties of neuronal populations over single neurons is a longstanding goal for both basic and applied neurosciences, with a specifically suitable application in the field of neuroprosthesis development, aimed to restore the loss of function of a visual cortex as a result of an injury or disease. We study how the interstimulus interval (ISI) period of a repeated visual stimulus influences the overall activity of rat visual cortex neuronal populations. Our results suggest that certain (3, 5 s) interstimulus intervals do have an increased stimulus response compared to longer or shorter ISIs for a 500 ms grating drifting stimulus. Based on the preliminary results shown in this article, we claim the need of a better understanding of the biological dynamics of the visual cortex neuronal populations in order to properly design suitable brain-machine interfaces for visual neurorehabilitation intracortical neuroprosthetics.
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Alegre-Cortés, J., Fernández, E., Soto-Sánchez, C. (2015). Interstimulus Interval Affects Population Response in Visual Cortex in vivo . In: Ferrández Vicente, J., Álvarez-Sánchez, J., de la Paz López, F., Toledo-Moreo, F., Adeli, H. (eds) Artificial Computation in Biology and Medicine. IWINAC 2015. Lecture Notes in Computer Science(), vol 9107. Springer, Cham. https://doi.org/10.1007/978-3-319-18914-7_22
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DOI: https://doi.org/10.1007/978-3-319-18914-7_22
Publisher Name: Springer, Cham
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