Abstract
Deep learning nowadays offers expert-level and sometimes even super-expert-level performance, but achieving such performance demands massive annotated data for training (e.g., Google’s proprietary CXR Foundation Model (CXR-FM) was trained on 821,544 labeled and mostly private chest X-rays (CXRs)). Numerous datasets are publicly available in medical imaging but individually small and heterogeneous in expert labels. We envision a powerful and robust foundation model that can be trained by aggregating numerous small public datasets. To realize this vision, we have developed Ark, a framework that accrues and reuses knowledge from heterogeneous expert annotations in various datasets. As a proof of concept, we have trained two Ark models on 335,484 and 704,363 CXRs, respectively, by merging several datasets including ChestX-ray14, CheXpert, MIMIC-II, and VinDr-CXR, evaluated them on a wide range of imaging tasks covering both classification and segmentation via fine-tuning, linear-probing, and gender-bias analysis, and demonstrated our Ark’s superior and robust performance over the state-of-the-art (SOTA) fully/self-supervised baselines and Google’s proprietary CXR-FM. This enhanced performance is attributed to our simple yet powerful observation that aggregating numerous public datasets diversifies patient populations and accrues knowledge from diverse experts, yielding unprecedented performance yet saving annotation cost. With all codes and pretrained models released at GitHub.com/JLiangLab/Ark, we hope that Ark exerts an important impact on open science, as accruing and reusing knowledge from expert annotations in public datasets can potentially surpass the performance of proprietary models trained on unusually large data, inspiring many more researchers worldwide to share codes and datasets to build open foundation models, accelerate open science, and democratize deep learning for medical imaging.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
RSNA pneumonia detection challenge (2018). https://www.kaggle.com/c/rsna-pneumonia-detection-challenge
SIIM-ACR pneumothorax segmentation (2019). https://kaggle.com/competitions/siim-acr-pneumothorax-segmentation
Collins, J.: Chest wall trauma. J. Thorac. Imaging 15(2), 112–119 (2000)
Irvin, J., et al.: CheXpert: a large chest radiograph dataset with uncertainty labels and expert comparison. In: Proceedings of the AAAI Conference on Artificial Intelligence, vol. 33, pp. 590–597 (2019)
Jaeger, S., Candemir, S., Antani, S., Wáng, Y.X.J., Lu, P.X., Thoma, G.: Two public chest x-ray datasets for computer-aided screening of pulmonary diseases. Quant. Imaging Med. Surg. 4(6), 475 (2014)
Johnson, A.E., et al.: MIMIC-CXR, a de-identified publicly available database of chest radiographs with free-text reports. Sci. Data 6(1), 1–8 (2019)
Kemker, R., McClure, M., Abitino, A., Hayes, T., Kanan, C.: Measuring catastrophic forgetting in neural networks. In: Proceedings of the AAAI Conference on Artificial Intelligence, vol. 32 (2018)
Larrazabal, A.J., Nieto, N., Peterson, V., Milone, D.H., Ferrante, E.: Gender imbalance in medical imaging datasets produces biased classifiers for computer-aided diagnosis. Proc. Natl. Acad. Sci. 117(23), 12592–12594 (2020)
Liu, Z., et al.: Swin transformer: hierarchical vision transformer using shifted windows. In: Proceedings of the IEEE/CVF International Conference on Computer Vision, pp. 10012–10022 (2021)
Ma, D., et al.: Benchmarking and boosting transformers for medical image classification. In: Kamnitsas, K., et al. (eds.) Domain Adaptation and Representation Transfer, DART 2022. Lecture Notes in Computer Science, vol. 13542, pp. 12–22. Springer, Cham (2022). https://doi.org/10.1007/978-3-031-16852-9_2
Mason, R.J., et al.: Murray and Nadel’s Textbook of Respiratory Medicine E-Book: 2-Volume Set. Elsevier Health Sciences (2010)
McMahan, B., Moore, E., Ramage, D., Hampson, S., y Arcas, B.A.: Communication-efficient learning of deep networks from decentralized data. In: Artificial Intelligence and Statistics, pp. 1273–1282. PMLR (2017)
Nguyen, H.Q., et al.: VinDr-CXR: an open dataset of chest x-rays with radiologist’s annotations. Sci. Data 9(1), 429 (2022)
Nguyen, H.C., Le, T.T., Pham, H.H., Nguyen, H.Q.: VinDr-RibCXR: a benchmark dataset for automatic segmentation and labeling of individual ribs on chest x-rays. In: Medical Imaging with Deep Learning (2021)
Peng, Y., Wang, X., Lu, L., Bagheri, M., Summers, R., Lu, Z.: NegBio: a high-performance tool for negation and uncertainty detection in radiology reports. AMIA Summits Transl. Sci. Proc. 2018, 188 (2018)
Sellergren, A.B., et al.: Simplified transfer learning for chest radiography models using less data. Radiology 305(2), 454–465 (2022)
Shiraishi, J., et al.: Development of a digital image database for chest radiographs with and without a lung nodule: receiver operating characteristic analysis of radiologists’ detection of pulmonary nodules. Am. J. Roentgenol. 174(1), 71–74 (2000)
Tarvainen, A., Valpola, H.: Mean teachers are better role models: weight-averaged consistency targets improve semi-supervised deep learning results. In: Advances in Neural Information Processing Systems, vol. 30 (2017)
Wang, X., Peng, Y., Lu, L., Lu, Z., Bagheri, M., Summers, R.M.: ChestX-ray8: hospital-scale chest x-ray database and benchmarks on weakly-supervised classification and localization of common thorax diseases. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 2097–2106 (2017)
Xiao, T., Liu, Y., Zhou, B., Jiang, Y., Sun, J.: Unified perceptual parsing for scene understanding. In: Ferrari, V., Hebert, M., Sminchisescu, C., Weiss, Y. (eds.) ECCV 2018. LNCS, vol. 11209, pp. 432–448. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-01228-1_26
Xie, Z., et al.: SimMIM: a simple framework for masked image modeling. In: Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition, pp. 9653–9663 (2022)
Zhu, Z., Kang, M., Yuille, A., Zhou, Z.: Assembling existing labels from public datasets to diagnose novel diseases: Covid-19 in late 2019. In: NeurIPS Workshop on Medical Imaging meets NeurIPS (2022)
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
1 Electronic supplementary material
Below is the link to the electronic supplementary material.
Rights and permissions
Copyright information
© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG
About this paper
Cite this paper
Ma, D., Pang, J., Gotway, M.B., Liang, J. (2023). Foundation Ark: Accruing and Reusing Knowledge for Superior and Robust Performance. In: Greenspan, H., et al. Medical Image Computing and Computer Assisted Intervention – MICCAI 2023. MICCAI 2023. Lecture Notes in Computer Science, vol 14220. Springer, Cham. https://doi.org/10.1007/978-3-031-43907-0_62
Download citation
DOI: https://doi.org/10.1007/978-3-031-43907-0_62
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-031-43906-3
Online ISBN: 978-3-031-43907-0
eBook Packages: Computer ScienceComputer Science (R0)