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Online Reflective Learning for Robust Medical Image Segmentation

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Medical Image Computing and Computer Assisted Intervention – MICCAI 2022 (MICCAI 2022)

Abstract

Deep segmentation models often face the failure risks when the testing image presents unseen distributions. Improving model robustness against these risks is crucial for the large-scale clinical application of deep models. In this study, inspired by human learning cycle, we propose a novel online reflective learning framework (RefSeg) to improve segmentation robustness. Based on the reflection-on-action conception, our RefSeg firstly drives the deep model to take action to obtain semantic segmentation. Then, RefSeg triggers the model to reflect itself. Because making deep models realize their segmentation failures during testing is challenging, RefSeg synthesizes a realistic proxy image from the semantic mask to help deep models build intuitive and effective reflections. This proxy translates and emphasizes the segmentation flaws. By maximizing the structural similarity between the raw input and the proxy, the reflection-on-action loop is closed with segmentation robustness improved. RefSeg runs in the testing phase and is general for segmentation models. Extensive validation on three medical image segmentation tasks with a public cardiac MR dataset and two in-house large ultrasound datasets show that our RefSeg remarkably improves model robustness and reports state-of-the-art performance over strong competitors.

Y. Huang and X. Yang—Contribute equally to this work.

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Acknowledgement

This work was supported by the grant from National Natural Science Foundation of China (Nos. 62171290, 62101343), Shenzhen-Hong Kong Joint Research Program (No. SGDX20201103095613036), and Shenzhen Science and Technology Innovations Committee (No. 20200812143441001).

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Correspondence to Dong Ni .

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Huang, Y. et al. (2022). Online Reflective Learning for Robust Medical Image Segmentation. In: Wang, L., Dou, Q., Fletcher, P.T., Speidel, S., Li, S. (eds) Medical Image Computing and Computer Assisted Intervention – MICCAI 2022. MICCAI 2022. Lecture Notes in Computer Science, vol 13438. Springer, Cham. https://doi.org/10.1007/978-3-031-16452-1_62

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  • DOI: https://doi.org/10.1007/978-3-031-16452-1_62

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  • Online ISBN: 978-3-031-16452-1

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