Abstract
The current paper challenges convolutional neural networks to address the computationally undebated task of recognizing four key views in first trimester fetal heart scanning (the aorta, the arches, the atrioventricular flows and the crossing of the great vessels). This is the primary inspection of the heart of a future baby and an early recognition of possible problems is important for timely intervention. Frames depicting the views of interest were labeled by obstetricians and given to several deep learning architectures as a classification task against other irrelevant scan sights. A test accuracy of 95% with an F1-score ranging from 90.91% to 99.58% for the four key perspectives shows the potential in supporting heart scans even from such an early fetal age, when the heart is still quite underdeveloped .
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Benhammou, Y., Achchab, B., Herrera, F., Tabik, S.: Breakhis based breast cancer automatic diagnosis using deep learning: taxonomy, survey and insights. Neurocomputing 375, 9–24 (2019)
Bridge, C.P., Ioannou, C., Noble, J.A.: Automated annotation and quantitative description of ultrasound videos of the fetal heart. Med. Image Anal. 36, 147–161 (2017)
Cara, M., Tudorache, S., Dimieru, R., Florea, M., Patru, C., Iliescu, D.: Prenatal first trimester assessment of the heart. Ann. Cardiol. Cardiovasc. Med. 1(2), 1008 (2017)
Cui, S., et al.: Development and clinical application of deep learning model for lung nodules screening on CT images. Sci. Rep. 10, 1–10 (2020)
Dozen, A., et al.: Image segmentation of the ventricular septum in fetal cardiac ultrasound videos based on deep learning using time-series information. Biomolecules 10(11), 1526 (2020)
Esteva, A., et al.: Deep learning-enabled medical computer vision. NPJ Digit. Med. 4, 5 (2021)
Garcia-Canadilla, P., Sánchez Martínez, S., Crispi, F., Bijnens, B.: Machine learning in fetal cardiology: what to expect. Fetal Diagn. Ther. 47, 363–372 (2020)
Huang, W., Bridge, C.P., Noble, J.A., Zisserman, A.: Temporal HeartNet: towards human-level automatic analysis of fetal cardiac screening video. In: Descoteaux, M., Maier-Hein, L., Franz, A., Jannin, P., Collins, D.L., Duchesne, S. (eds.) MICCAI 2017. LNCS, vol. 10434, pp. 341–349. Springer, Cham (2017). https://doi.org/10.1007/978-3-319-66185-8_39
Hutchinson, D., et al.: First-trimester fetal echocardiography: identification of cardiac structures for screening from 6 to 13 weeks’ gestational age. J. Am. Soc. Echocardiogr. 30(8), 763–772 (2017)
Iliescu, D., et al.: Improved detection rate of structural abnormalities in the first trimester using an extended examination protocol. Ultrasound Obstet. Gynecol. 42(3), 300–309 (2013)
Jicinska, H., et al.: Does first-trimester screening modify the natural history of congenital heart disease? Circulation 135(11), 1045–1055 (2017)
Komatsu, M., et al.: Detection of cardiac structural abnormalities in fetal ultrasound videos using deep learning. Appl. Sci. 11(1), 371 (2021)
Letourneau, K., Horne, D., Soni, R., McDonald, K., Karlicki, F., Fransoo, R.: Advancing prenatal detection of congenital heart disease: a novel screening protocol improves early diagnosis of complex congenital heart disease. Obstet. Gynecol. Surv. 73, 557–559 (2018)
Lichtblau, D., Stoean, C.: Cancer diagnosis through a tandem of classifiers for digitized histopathological slides. PLoS ONE 14(1), 1–20 (2019)
Lindgren Belal, S., et al.: Deep learning for segmentation of 49 selected bones in CT scans: first step in automated PET/CT-based 3D quantification of skeletal metastases. Eur. J. Radiol. 113, 89–95 (2019)
Litjens, G., et al.: A survey on deep learning in medical image analysis. Med. Image Anal. 42, 60–88 (2017)
Lundervold, A.S., Lundervold, A.: An overview of deep learning in medical imaging focusing on MRI. Zeitschrift für Medizinische Physik 29(2), 102–127 (2019). special Issue: Deep Learning in Medical Physics
Mittal, S., Stoean, C., Kajdacsy-Balla, A., Bhargava, R.: Digital assessment of stained breast tissue images for comprehensive tumor and microenvironment analysis. Front. Bioeng. Biotechnol. 7, 246 (2019)
Patel, N., Narasimhan, E., Kennedy, A.: Fetal cardiac us: techniques and normal anatomy correlated with adult CT and MR imaging. RadioGraphics 37(4), 1290–1303 (2017)
Piccialli, F., Somma, V.D., Giampaolo, F., Cuomo, S., Fortino, G.: A survey on deep learning in medicine: why, how and when? Inf. Fusion 66, 111–137 (2021)
Pinto, N.M., Morris, S.A., Moon-Grady, A.J., Donofrio, M.T.: Prenatal cardiac care: goals, priorities & gaps in knowledge in fetal cardiovascular disease: perspectives of the fetal heart society. Prog. Pediatr. Cardiol. 59, 101312 (2020)
Sherkatghanad, Z., et al.: Automated detection of autism spectrum disorder using a convolutional neural network. Front. Neurosci. 13, 1325 (2019)
Smith, L.N.: A disciplined approach to neural network hyper-parameters: part 1 - learning rate, batch size, momentum, and weight decay (2018)
Stoean, R.: Analysis on the potential of an EA-surrogate modelling tandem for deep learning parametrization: an example for cancer classification from medical images. Neural Comput. Appl. 32, 313–322 (2020)
Stoean, R., et al.: Automated detection of presymptomatic conditions in spinocerebellar ataxia type 2 using monte-carlo dropout and deep neural network techniques with electrooculogram signals. Sensors 20(11), 3032 (2020)
Stoean, R., Stoean, C., Atencia, M., Rodríguez-Labrada, R., Joya, G.: Ranking information extracted from uncertainty quantification of the prediction of a deep learning model on medical time series data. Mathematics 8(7), 1078 (2020)
Tudorache, S., Cara, M., Iliescu, D.G., Novac, L., Cernea, N.: First trimester two- and four-dimensional cardiac scan: intra- and interobserver agreement, comparison between methods and benefits of color doppler technique. Ultrasound Obstet. Gynecol. 42(6), 659–668 (2013)
Wang, J., et al.: Automated interpretation of congenital heart disease from multi-view echocardiograms. Med. Image Anal. 69, 101942 (2021)
Yamanakkanavar, N., Choi, J.Y., Lee, B.: MRI segmentation and classification of human brain using deep learning for diagnosis of Alzheimer’s disease: a survey. Sensors 20(11), 3243 (2020)
Acknowledgement
This work was supported by a grant of the Romanian Ministry of Research and Innovation, CCCDI – UEFISCDI, project number 408PED/2020, PN-III-P2-2.1-PED-2019-2227, Learning deep architectures for the Interpretation of Fetal Echocardiography (LIFE), within PNCDI III, as well as the Plan Propio de Investigación, Transferencia y Divulgación Científica of the Universidad de Málaga.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2021 Springer Nature Switzerland AG
About this paper
Cite this paper
Stoean, R. et al. (2021). Deep Learning for the Detection of Frames of Interest in Fetal Heart Assessment from First Trimester Ultrasound. In: Rojas, I., Joya, G., Català, A. (eds) Advances in Computational Intelligence. IWANN 2021. Lecture Notes in Computer Science(), vol 12861. Springer, Cham. https://doi.org/10.1007/978-3-030-85030-2_1
Download citation
DOI: https://doi.org/10.1007/978-3-030-85030-2_1
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-85029-6
Online ISBN: 978-3-030-85030-2
eBook Packages: Computer ScienceComputer Science (R0)