Nothing Special   »   [go: up one dir, main page]

Skip to main content

Two-Stage Method for Segmentation of the Myocardial Scars and Edema on Multi-sequence Cardiac Magnetic Resonance

  • Conference paper
  • First Online:
Myocardial Pathology Segmentation Combining Multi-Sequence Cardiac Magnetic Resonance Images (MyoPS 2020)

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 12554))

Abstract

Segmenting cardiac scars and edema from cardiac magnetic resonance (CMR) are essential for the early diagnosis and accurate prognostic assessment of ischemic heart disease. The pathological myocardium presents distinctive brightness in the late gadolinium enhancement (LGE) images, the T2-weighted CMR shows the acute injury and ischemic regions, and the balanced-Steady State Free Precession (bSSFP) can clearly reveal the boundaries of the myocardium. Given this fact, we proposed a novel fully-automatic two-stage method to extract different features of each modality as well as segment myocardium edema and scars. In the first stage, a U-net was trained on bSSFP images with full annotation of myocardium, which can locate the coarse position of the myocardium and obtain the mask of the myocardium as a constraint on the next stage. In the second stage, with the T2 images, LGE images and predicted myocardium masks concatenated as inputs, an M-shaped network based on attention mechanism was trained to segment the myocardial edema and scars accurately. In conclusion, the accuracy of the segmentation was improved by adopting prior constraints and attention mechanism, which achieved an average Dice score of 0.570 and 0.634 for the myocardial scars and myocardial scars+edema respectively on the test set of MyoPS 2020.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

Change history

  • 21 December 2020

    The original version of this chapter was revised. The institute Shanghai United Imaging Intelligence, Co., Ltd., Shanghai, China of the author Dongdong Gu has been removed and the acknowledgement was changed to “This work was supported by the National Natural Science Foundation of China (61671204).”

References

  1. Fahmy, A.S., et al.: Three-dimensional deep convolutional neural networks for automated myocardial scar quantification in hypertrophic cardiomyopathy: a multicenter multivendor study. Radiology 294(1), 52–60 (2020)

    Article  Google Scholar 

  2. Fu, H., Cheng, J., Xu, Y., Wong, D.W.K., Liu, J., Cao, X.: Joint optic disc and cup segmentation based on multi-label deep network and polar transformation. IEEE Trans. Med. Imaging 37(7), 1597–1605 (2018)

    Article  Google Scholar 

  3. He, K., Zhang, X., Ren, S., Sun, J.: Deep residual learning for image recognition. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 770–778 (2016)

    Google Scholar 

  4. Lin, A., Kolossváry, M., Išgum, I., Maurovich-Horvat, P., Slomka, P.J., Dey, D.: Artificial intelligence: improving the efficiency of cardiovascular imaging. Expert. Rev. Med. Devices 17(6), 565–577 (2020). https://doi.org/10.1080/17434440.2020.1777855

    Article  Google Scholar 

  5. Long, J., Shelhamer, E., Darrell, T.: Fully convolutional networks for semantic segmentation. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 3431–3440 (2015)

    Google Scholar 

  6. Singh, G., et al.: Deep learning based automatic segmentation of cardiac computed tomography. J. Am. Coll. Cardiol. 73(9), 1643 (2019)

    Article  Google Scholar 

  7. Tavakoli, V., Amini, A.A.: A survey of shaped-based registration and segmentation techniques for cardiac images. Comput. Vis. Image Underst. 117(9), 966–989 (2013)

    Article  Google Scholar 

  8. Wang, P., Chung, A.C.S.: Focal dice loss and image dilation for brain tumor segmentation. In: Stoyanov, D., et al. (eds.) DLMIA/ML-CDS -2018. LNCS, vol. 11045, pp. 119–127. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-00889-5_14

    Chapter  Google Scholar 

  9. Woo, S., Park, J., Lee, J.-Y., Kweon, I.S.: CBAM: convolutional block attention module. In: Ferrari, V., Hebert, M., Sminchisescu, C., Weiss, Y. (eds.) ECCV 2018. LNCS, vol. 11211, pp. 3–19. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-01234-2_1

    Chapter  Google Scholar 

  10. Xu, Z., Wu, Z., Feng, J.: CFUN: combining faster R-CNN and U-net network for efficient whole heart segmentation. arXiv preprint arXiv:1812.04914 (2018)

  11. Zabihollahy, F., White, J.A., Ukwatta, E.: Fully automated segmentation of left ventricular myocardium from 3D late gadolinium enhancement magnetic resonance images using a U-net convolutional neural network-based model. In: Medical Imaging 2019: Computer-Aided Diagnosis, vol. 10950, p. 109503C. International Society for Optics and Photonics (2019)

    Google Scholar 

  12. Zhuang, X.: Multivariate mixture model for cardiac segmentation from multi-sequence MRI. In: Ourselin, S., Joskowicz, L., Sabuncu, M.R., Unal, G., Wells, W. (eds.) MICCAI 2016. LNCS, vol. 9901, pp. 581–588. Springer, Cham (2016). https://doi.org/10.1007/978-3-319-46723-8_67

    Chapter  Google Scholar 

  13. Zhuang, X.: Multivariate mixture model for myocardial segmentation combining multi-source images. IEEE Trans. Pattern Anal. Mach. Intell. 41(12), 2933–2946 (2019)

    Article  Google Scholar 

Download references

Acknowledgement

This work was supported by the National Natural Science Foundation of China (61671204).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Guocai Liu .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Switzerland AG

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Liu, Y., Zhang, M., Zhan, Q., Gu, D., Liu, G. (2020). Two-Stage Method for Segmentation of the Myocardial Scars and Edema on Multi-sequence Cardiac Magnetic Resonance. In: Zhuang, X., Li, L. (eds) Myocardial Pathology Segmentation Combining Multi-Sequence Cardiac Magnetic Resonance Images. MyoPS 2020. Lecture Notes in Computer Science(), vol 12554. Springer, Cham. https://doi.org/10.1007/978-3-030-65651-5_3

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-65651-5_3

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-65650-8

  • Online ISBN: 978-3-030-65651-5

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics