Abstract
Extracting biomedical triplet is one of the most important tasks in medical knowledge graph construction. Relations in complex biomedical text are overlap heavily. Although existing biomedical relation extraction methods have higher accuracy, they still have two problems. First, most of those methods hardly consider relations overlap problem. A lot of precious biomedical information is neglected. In addition, the entities in biomedical text are intensive, and the contextual information association also affects the understanding of the meaning of biomedical texts. Methods often used to encode sentence, like canonical bidirectional recurrent neural networks (BiRNN) or convolutional neural networks (CNN), are difficult to capture enough information from biomedical text. In this paper, we propose a new end-to-end triplet extraction method to address the complex triplet extraction problem in biomedical text. In our model, sentences are encoded by Recurrent Convolutional Neural Network (RCNN), which combines the advantages of BiRNN and CNN flexibly, containing more information of sentence. Experimental results on biomedical dataset and general field dataset show that our method is effective.
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References
Luo, Y., et al.: Segment convolutional neural networks (Seg-CNNs) for classifying relations in clinical notes. J. Am. Med. Inform. Assoc. 25(1), 93–98 (2018)
Luo, Y.: Recurrent neural networks for classifying relations in clinical notes. J. Biomed. Inform. 72, 85–95 (2017)
He, B., Guan, Y., Dai, R.: Classifying medical relations in clinical text via convolutional neural networks. Artif. Intell. Med. 93, 43–49 (2019)
Uzuner, Ö., South, B.R., Shen, S., et al.: 2010 i2b2/VA challenge on concepts, assertions, and relations in clinical text. J. Am. Med. Inform. Assoc. 18(5), 552–556 (2011)
Li, F., Zhang, M., Fu, G., et al.: A neural joint model for entity and relation extraction from biomedical text. BMC Bioinform. 18(1), 198 (2017)
Zeng, X., et al.: Extracting relational facts by an end-to-end neural model with copy mechanism. In: Proceedings of the 56th Annual Meeting of the Association for Computational Linguistics. Long Papers, vol. 1 (2018)
Lai, S., Xu, L., Liu, K., Zhao, J.: Recurrent convolutional neural networks for text classification. In: Twenty-Ninth AAAI Conference on Artificial Intelligence (2015)
Nguyen, T.H., Grishman, R.: Relation extraction: perspective from convolutional neural networks. In: Proceedings of the 1st Workshop on Vector Space Modeling for Natural Language Processing, pp. 39–48 (2015)
Xu, K., Zhou, Z., Hao, T., Liu, W.: A bidirectional LSTM and conditional random fields approach to medical named entity recognition. In: Hassanien, A.E., Shaalan, K., Gaber, T., Tolba, Mohamed F. (eds.) AISI 2017. AISC, vol. 639, pp. 355–365. Springer, Cham (2018). https://doi.org/10.1007/978-3-319-64861-3_33
Zhu, Ji., et al.: Relation classification via target-concentrated attention CNNs (2017)
Miwa, M., Bansal, M.: End-to-end relation extraction using LSTMs on sequences and tree structures. In: Proceedings of ACL, pp. 1105–1116 (2016)
Zheng, S., et al.: Joint entity and relation extraction based on a hybrid neural network. Neurocomputing 257, 59–66 (2017)
Gupta, P., Schtze, H., Andrassy, B.: Table filling multi-task recurrent neural network for joint entity and relation extraction. In: Proceedings of COLING, pp. 2537–2547 (2016)
Li, Q., Ji, H.: Incremental joint extraction of entity mentions and relations. In: Proceedings of ACL, pp. 402–412 (2014)
Miwa, M., Sasaki, Y.: Modeling joint entity and relation extraction with table representation. In: Proceedings of EMNLP, pp. 1858–1869 (2014)
Yu, X., Lam, W.: Jointly identifying entities and extracting relations in encyclopedia text via a graphical model approach. In: Proceedings of COLING, pp. 1399–1407 (2010)
Zheng, S., et al.: Joint extraction of entities and relations based on a novel tagging scheme (2017)
Chung, J., Gulcehre, C., Cho, K., Bengio, Y.: Empirical evaluation of gated recurrent neural networks on sequence modeling (2014). arXiv preprint: arXiv:1412.3555
Hochreiter, S., Schmidhuber, J.: Long short-term memory. Neural Comput. 9(8), 1735–1780 (1997)
Klambauer, G., Unterthiner, T., Mayr, A., Hochreiter, S.: Self-normalizing neural networks. In: Advances in NIPS, pp. 971–980 (2017)
Sahu, S.K., Anand, A., Oruganty, K., Gattu, M.: Relation extraction from clinical texts using domain invariant convolutional neural network (2016). arXiv preprint: arXiv:1606.09370
Nltk toolkit. https://www.nltk.org/_modules/nltk/tokenize.html
Kingma, D.P., Ba, J.L.: Adam: a method for stochastic optimization. In: Proceedings of ICLR, pp. 1–15 (2015)
PubMed-w2v.bin word vector. http://evexdb.org/pmresources/vec-space-models/
Acknowledgments
This work was supported by the National key research and development program of China (No. 2017YFE0117500), National Key R&D Program of China, Grant (NO. 2016YFC0901904, 2016YFC0901604) and Science and Technology Committee of Shanghai Municipality (No. 16010500400).
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Wang, X., Li, Q., Ding, X., Zhang, G., Weng, L., Ding, M. (2019). A New Method for Complex Triplet Extraction of Biomedical Texts. In: Douligeris, C., Karagiannis, D., Apostolou, D. (eds) Knowledge Science, Engineering and Management. KSEM 2019. Lecture Notes in Computer Science(), vol 11776. Springer, Cham. https://doi.org/10.1007/978-3-030-29563-9_15
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DOI: https://doi.org/10.1007/978-3-030-29563-9_15
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