Nothing Special   »   [go: up one dir, main page]

Skip to main content

Security and Innovation Protection of Biochips

  • Reference work entry
  • First Online:
Handbook of Biochips
  • 2743 Accesses

Abstract

The miniaturization of microfluidic device components has greatly improved the scale and convenience of biochip. Undoubtedly, there will be a booming market for biochips in the future. Owning to the popularization potential of biochip, it has also became a target for attackers. This chapter presents about the security and innovation protection of biochip, including attack technologies, security threat effects, and protection technologies. Two mainly attacked technologies hardware Trojan (HT) and reverse engineering (RE) are introduced. Both HT and RE involve the destruction from physical structure to bioassay; thus, the discussion is extended into the several security threat effects. Moreover, the protection approaches responds to attacks from three aspects: (1) intellectual property (IP) protection directly facing the bioassay security, (2) some reliable methods detecting the existence of the attacks early, and (3) camouflage and obfuscation preventing the above two attack technologies effectively. Additionally, this chapter also discusses some possible security threats and countermeasures for future biochips.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 1,200.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 1,099.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  • Ali SS, Ibrahim M, Rajendran J, Sinanoglu O, Chakrabarty K (2016a) Supply-chain security of digital microfluidic biochips. Computer 49:36–43

    Article  Google Scholar 

  • Ali SS, Ibrahim M, Sinanoglu O, Chakrabarty K, Karri R (2016b) Microfluidic encryption of on-chip biochemical assays. In: Proceedings of the biomedical circuits and systems conference, Shanghai, 17–19 Oct 2016, pp 152–155

    Google Scholar 

  • Bar-El H, Choukri H, Naccache D, Tunstall M, Whelan C (2006) The sorcerer’s apprentice guide to fault attacks. Proc IEEE 94(2):370–382

    Article  Google Scholar 

  • Bhattacharjee S, Tang J, Ibrahim M, Chakrabarty K, Karri R (2018) Locking of biochemical assays for digital microfluidic biochips. In: Proceedings of the 23rd European Test Symposium, Bremen, 28 May–1 June 2018, pp 1–6

    Google Scholar 

  • Bhunia S, Hsiao MS, Banga M, Narasimhan S (2014) Hardware trojan attacks: threat analysis and countermeasures. Proc IEEE 102(8):1229–1247

    Article  Google Scholar 

  • Chen H, Potluri S, Koushanfar F (2017a) Biochipwork: reverse engineering of microfluidic biochips. In: Proceedings of the international conference on computer design, Boston, 5–8 Nov 2017, pp 9–16

    Google Scholar 

  • Chen X, Qu G, Cui A (2017b) Practical IP watermarking and fingerprinting methods for ASIC designs. In: Proceedings of the international symposium on circuits and systems, Baltimore, 28–31 May 2017, pp 1–4

    Google Scholar 

  • Chen H, Potluri S, Koushanfar F (2020) Security of microfluidic biochip: practical attacks and countermeasures. ACM Trans Des Autom Electron Syst 25(3):1–29

    Article  Google Scholar 

  • Dong C, Liu L, Liu H, Guo W, Ho TY (2020a) A survey of DMFBs security: state-of-the-art attack and defense. In: 2020 21st International Symposium on Quality Electronic Design (ISQED), Santa Clara, 25–26 Mar 2020, pp 14–20

    Google Scholar 

  • Dong C, Xu Y, Liu X, Zhang F, He G, Chen Y (2020b) Hardware trojans in chips: a survey for detection and prevention. Sensors 20(5165):1–37

    Google Scholar 

  • Liang TC, Chakrabarty K, Karri R (2020) Programmable daisychaining of microelectrodes to secure bioassay IP in meda biochips. IEEE Trans Very Large Scale Integr VLSI Syst 28(5):1269–1282

    Article  Google Scholar 

  • Lin CY, Huang JD, Yao H, Ho TY (2018) A comprehensive security system for digital microfluidic biochips. In: Proceedings of the international test conference in Asia, Harbin, 15–17 Aug 2018, pp 151–156

    Google Scholar 

  • Ruehrmair U, van Dijk M (2013) Pufs in security protocols: attack models and security evaluations. In: Proceedings of 2013 IEEE symposium on security and privacy, Berkeley, 19–22 May 2013, pp 286–300

    Google Scholar 

  • Shayan M, Bhattacharjee S, Song YA, Chakrabarty K, Karri R (2019a) Desieve the attacker: thwarting IP theft in sieve-valve-based biochips. In: 2019 design, automation & test in Europe conference & exhibition (DATE), Florence, 25–29 Mar 2019, pp 210–215

    Google Scholar 

  • Shayan M, Bhattacharjee S, Song YA, Chakrabarty K, Karri R (2019b) Security assessment of microfluidic fully-programmable-valve-array biochips. In: 2019 32nd international conference on VLSI design and 2019 18th international conference on embedded systems (VLSID), Delhi, 5–9 Jan 2019, pp 197–202

    Google Scholar 

  • Shayan M, Tang J, Chakrabarty K, Karri R (2019c) Security assessment of micro-electrode-dot-array biochips. IEEE Trans Comput Aided Des Integr Circuits Syst 38(10):1831–1843

    Article  Google Scholar 

  • Shayan M, Bhattacharjee S, Song YA, Chakrabarty K, Karri R (2020) Microfluidic trojan design in flow-based biochips. In: 2020 design, automation & test in Europe conference & exhibition (DATE), Grenoble, 9–13 Mar 2020, pp 1037–1042

    Google Scholar 

  • Singh A, Samanta T (2016) Vulnerability detection and error minimization in bioassay sample mixing and droplet routing for digital microfluidic biochips. In: Sixth international symposium on embedded computing & system design, Patna, 15–17 Dec 2016, pp 66–71

    Google Scholar 

  • Tang J, Ibrahim M, Chakrabarty K, Karri R (2017) Security trade-offs in microfluidic routing fabrics. In: IEEE international conference on computer design, Boston, 5–8 Nov 2017, pp 25–32

    Google Scholar 

  • Tang J, Ibrahim M, Chakrabarty K, Karri R (2018a) Secure randomized checkpointing for digital microfluidic biochips. IEEE Trans Comput Aided Des Integr Circuits Syst 37(6):1119–1132

    Article  Google Scholar 

  • Tang J, Ibrahim M, Chakrabarty K, Karri R (2018b) Toward secure and trustworthy cyberphysical microfluidic biochips. IEEE Trans Comput Aided Des Integr Circuits Syst 38:589–603

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ximeng Liu .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2022 Springer Science+Business Media, LLC, part of Springer Nature

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Dong, C., Liu, X., Xu, Y., Lian, S. (2022). Security and Innovation Protection of Biochips. In: Sawan, M. (eds) Handbook of Biochips. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-3447-4_62

Download citation

Publish with us

Policies and ethics