Nothing Special   »   [go: up one dir, main page]

P2RY1

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

P2RY1

P2Y purinoceptor 1 is a protein that in humans is encoded by the P2RY1 gene.[5]

Quick Facts Available structures, PDB ...
P2RY1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesP2RY1, P2Y1, purinergic receptor P2Y1, SARCC
External IDsOMIM: 601167; MGI: 105049; HomoloGene: 1926; GeneCards: P2RY1; OMA:P2RY1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002563

NM_001282016
NM_008772

RefSeq (protein)

NP_002554

NP_001268945
NP_032798

Location (UCSC)Chr 3: 152.84 – 152.84 MbChr 3: 60.91 – 60.92 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
Close

Function

The product of this gene, P2Y1 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.[6]

See also

References

Further reading

Wikiwand - on

Seamless Wikipedia browsing. On steroids.