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Estradiol/drospirenone (E2/DRSP), sold under the brand name Angeliq, is a combination of estradiol (E2), an estrogen, and drospirenone (DRSP), a progestin, antimineralocorticoid, and antiandrogen, which is used in menopausal hormone therapy, specifically the treatment of menopausal syndrome and osteoporosis, in postmenopausal women.[1][2][3] It is taken by mouth and contains 0.5 to 1 mg E2 and 0.25 to 0.5 mg DRSP per tablet.[1] The medication was approved in the United States in 2005.[1] It is marketed widely throughout the world.[4]
 Estradiol | |
 Drospirenone | |
| Combination of | |
|---|---|
| Estradiol | Estrogen |
| Drospirenone | Progestogen; Progestin; Antimineralocorticoid; Antiandrogen |
| Clinical data | |
| Trade names | Angeliq |
| Other names | E2/DRSP; BAY-864891 |
| Routes of administration | By mouth |
| Drug class | Estrogen; Progestin; Progestogen; Antimineralocorticoid; Antiandrogen |
| Legal status | |
| Legal status |
|
| Identifiers | |
| CAS Number | |
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