Fanconi anaemia and cancer: an intricate relationship (Q49616542)

https://api.crossref.org/works/10.1038%2FNRC.2017.116

A novel Fanconi anaemia subtype associated with a dominant-negative mutation in RAD51

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

A Dominant Mutation in Human RAD51 Reveals Its Function in DNA Interstrand Crosslink Repair Independent of Homologous Recombination

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Deletion and reduced expression of the Fanconi anemia FANCA gene in sporadic acute myeloid leukemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Bi-allelic silencing of the Fanconi anaemia gene FANCF in acute myeloid leukaemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Genotype-phenotype correlations in Fanconi anemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Fanconi anemia and its diagnosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Pathophysiology and management of inherited bone marrow failure syndromes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Case records of the Massachusetts General Hospital. Case 13-2006. A 50-year-old man with a painful bone mass and lesions in the liver.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Delayed diagnosis and complications of Fanconi anaemia at advanced age--a paradigm

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Estimation of the prevalence of Fanconi anemia among patients with de novo acute myelogenous leukemia who have poor recovery from chemotherapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Evaluation and Management of Chronic Pancytopenia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Frequency and natural history of inherited bone marrow failure syndromes: the Israeli Inherited Bone Marrow Failure Registry.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

How high are carrier frequencies of rare recessive syndromes? Contemporary estimates for Fanconi Anemia in the United States and Israel

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

A common founder mutation in FANCA underlies the world's highest prevalence of Fanconi anemia in Gypsy families from Spain.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Fanconi anemia: another disease of unusually high prevalence in the Afrikaans population of South Africa

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Two common founder mutations of the fanconi anemia group G gene FANCG/XRCC9 in the Japanese population

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

A common Fanconi anemia mutation in black populations of sub-Saharan Africa

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Molecular and genealogical evidence for a founder effect in Fanconi anemia families of the Afrikaner population of South Africa

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

A novel diagnostic screen for defects in the Fanconi anemia pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

A 20-year perspective on the International Fanconi Anemia Registry (IFAR).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Androgen therapy in Fanconi anemia: A retrospective analysis of 30 years in Germany

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Androgens and liver tumors: Fanconi's anemia and non-Fanconi's conditions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Fanconi Anemia: Overview of the Disease and the Role of Hematopoietic Transplantation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Bone marrow transplantation from matched related donors for patients with Fanconi anemia using low-dose busulfan and cyclophosphamide as conditioning

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Fanconi anemia and the development of leukemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

High incidence of head and neck squamous cell carcinoma in patients with Fanconi anemia.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Risk of head and neck squamous cell cancer and death in patients with Fanconi anemia who did and did not receive transplants

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

The Bloom's syndrome gene product is homologous to RecQ helicases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Transfection of BLM into cultured bloom syndrome cells reduces the sister-chromatid exchange rate toward normal

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Bloom's Syndrome: Clinical Spectrum, Molecular Pathogenesis, and Cancer Predisposition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Aberrant chromosome morphology in human cells defective for Holliday junction resolution

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Direct and indirect roles of RECQL4 in modulating base excision repair capacity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

RECQL4 in genomic instability and aging

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Revisiting the craniosynostosis-radial ray hypoplasia association: Baller-Gerold syndrome caused by mutations in the RECQL4 gene

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

The mutation spectrum in RECQL4 diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Association between osteosarcoma and deleterious mutations in the RECQL4 gene in Rothmund-Thomson syndrome.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Forty years of research on xeroderma pigmentosum at the US National Institutes of Health.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Cancer and neurologic degeneration in xeroderma pigmentosum: long term follow-up characterises the role of DNA repair.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Mutations in ERCC4, encoding the DNA-repair endonuclease XPF, cause Fanconi anemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Malfunction of nuclease ERCC1-XPF results in diverse clinical manifestations and causes Cockayne syndrome, xeroderma pigmentosum, and Fanconi anemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Identification of the breast cancer susceptibility gene BRCA2

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Meta-analysis of BRCA1 and BRCA2 penetrance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Biallelic inactivation of BRCA2 in Fanconi anemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Clinical and molecular features associated with biallelic mutations in FANCD1/BRCA2.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

The clinical phenotype of children with Fanconi anemia caused by biallelic FANCD1/BRCA2 mutations

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Biallelic mutations in BRCA1 cause a new Fanconi anemia subtype

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Biallelic deleterious BRCA1 mutations in a woman with early-onset ovarian cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

The DNA helicase BRIP1 is defective in Fanconi anemia complementation group J

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

The BRCA1-interacting helicase BRIP1 is deficient in Fanconi anemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Genetic heterogeneity among Fanconi anemia heterozygotes and risk of cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

The risk for developing cancer in Israeli ATM, BLM, and FANCC heterozygous mutation carriers.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Exome sequencing identifies rare deleterious mutations in DNA repair genes FANCC and BLM as potential breast cancer susceptibility alleles

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Germline Mutations in Predisposition Genes in Pediatric Cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

AluY-mediated germline deletion, duplication and somatic stem cell reversion in UBE2T defines a new subtype of Fanconi anemia.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Exome sequencing identifies FANCM as a susceptibility gene for triple-negative breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Lifestyle and cancer risk

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Future directions in cancer prevention

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Epigenetic modulators, modifiers and mediators in cancer aetiology and progression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Aberrant Fanconi anaemia protein profiles in acute myeloid leukaemia cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Downregulation of Fanconi anemia genes in sporadic head and neck squamous cell carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

FANCD2 Maintains Fork Stability in BRCA1/2-Deficient Tumors and Promotes Alternative End-Joining DNA Repair

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

FANCD2 limits replication stress and genome instability in cells lacking BRCA2.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

High expression of DNA repair pathways is associated with metastasis in melanoma patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

FANCD2 mRNA overexpression is a bona fide indicator of lymph node metastasis in human colorectal cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

FANCD2 functions as a critical factor downstream of MiTF to maintain the proliferation and survival of melanoma cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Causes and consequences of aneuploidy in cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Hallmarks of Cancer: The Next Generation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Mechanism-driven biomarkers to guide immune checkpoint blockade in cancer therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

The mini-driver model of polygenic cancer evolution

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Mechanisms and clinical applications of chromosomal instability in lymphoid malignancy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Dissecting cancer evolution at the macro-heterogeneity and micro-heterogeneity scale.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Clonal evolution models of tumor heterogeneity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Cell cycle proteins as promising targets in cancer therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Cell cycle, CDKs and cancer: a changing paradigm

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Fueling the Cell Division Cycle

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Cancer etiology. Variation in cancer risk among tissues can be explained by the number of stem cell divisions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Substantial contribution of extrinsic risk factors to cancer development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

FANCD2 activates transcription of TAp63 and suppresses tumorigenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

ATM and ATR signaling at a glance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

p21WAF1 and tumourigenesis: 20 years after

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

ATR-dependent phosphorylation of FANCA on serine 1449 after DNA damage is important for FA pathway function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Chk1-mediated phosphorylation of FANCE is required for the Fanconi anemia/BRCA pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

ATR-dependent phosphorylation of FANCM at serine 1045 is essential for FANCM functions.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

RNF4-mediated polyubiquitination regulates the Fanconi anemia/BRCA pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Distinct functional roles for the two SLX4 ubiquitin-binding UBZ domains mutated in Fanconi anemia.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Crystal structure of a Fanconi anemia-associated nuclease homolog bound to 5' flap DNA: basis of interstrand cross-link repair by FAN1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Fanconi anemia proteins are required to prevent accumulation of replication-associated DNA double-strand breaks

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Collisions between replication and transcription complexes cause common fragile site instability at the longest human genes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Separate roles for the DNA damage checkpoint protein kinases in stabilizing DNA replication forks.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

The DNA crosslink-induced S-phase checkpoint depends on ATR-CHK1 and ATR-NBS1-FANCD2 pathways

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

The Fanconi Anemia Pathway Maintains Genome Stability by Coordinating Replication and Transcription

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

DNA interstrand crosslink repair and cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Mutations of the SLX4 gene in Fanconi anemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Mechanism of RAD51-dependent DNA interstrand cross-link repair.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Mutation of the RAD51C gene in a Fanconi anemia-like disorder

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

ATR activation and replication fork restart are defective in FANCM-deficient cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Preventing nonhomologous end joining suppresses DNA repair defects of Fanconi anemia.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Ku70 corrupts DNA repair in the absence of the Fanconi anemia pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Impaired TIP60-mediated H4K16 acetylation accounts for the aberrant chromatin accumulation of 53BP1 and RAP80 in Fanconi anemia pathway-deficient cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Fancd2 functions in a double strand break repair pathway that is distinct from non-homologous end joining

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

BRCA1 functions independently of homologous recombination in DNA interstrand crosslink repair

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

The Fanconi anaemia pathway: new players and new functions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

FANCD2 binds MCM proteins and controls replisome function upon activation of s phase checkpoint signaling.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Fanconi anemia signaling network regulates the spindle assembly checkpoint

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Centrosome dynamics as a source of chromosomal instability

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

A mechanism linking extra centrosomes to chromosomal instability

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

A centrosomal route for cancer genome instability

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

FANCA safeguards interphase and mitosis during hematopoiesis in vivo.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Cytokinesis failure occurs in Fanconi anemia pathway-deficient murine and human bone marrow hematopoietic cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

FancJ regulates interstrand crosslinker induced centrosome amplification through the activation of polo-like kinase 1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Fanconi anemia complementation group A (FANCA) localizes to centrosomes and functions in the maintenance of centrosome integrity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

BRCA2 and Nucleophosmin Coregulate Centrosome Amplification and Form a Complex with the Rho Effector Kinase ROCK2

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

The Fanconi Anemia C Protein Binds to and Regulates Stathmin-1 Phosphorylation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Regulation of kinetochore-microtubule attachments through homeostatic control during mitosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Signalling dynamics in the spindle checkpoint response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

BRCA2 fine-tunes the spindle assembly checkpoint through reinforcement of BubR1 acetylation.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Loss of BubR1 acetylation causes defects in spindle assembly checkpoint signaling and promotes tumor formation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Replication stress induces sister-chromatid bridging at fragile site loci in mitosis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

The SLX4 complex is a SUMO E3 ligase that impacts on replication stress outcome and genome stability

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Noncovalent interactions with SUMO and ubiquitin orchestrate distinct functions of the SLX4 complex in genome maintenance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

SUMO modification regulates BLM and RAD51 interaction at damaged replication forks

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

DNA breaks and chromosome pulverization from errors in mitosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Abnormal cytokinesis in cells deficient in the breast cancer susceptibility protein BRCA2

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Tetraploidy in BRCA2 breast tumours

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

BRCA2 phosphorylated by PLK1 moves to the midbody to regulate cytokinesis mediated by nonmuscle myosin IIC.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

BRCA2 localization to the midbody by filamin A regulates cep55 signaling and completion of cytokinesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Defective endomitosis during megakaryopoiesis leads to thrombocytopenia in Fanca-/- mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Elucidation of the Fanconi Anemia Protein Network in Meiosis and Its Function in the Regulation of Histone Modifications

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

FANCB is essential in the male germline and regulates H3K9 methylation on the sex chromosomes during meiosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

p53-Driven apoptosis limits centrosome amplification and genomic instability downstream of NPM1 phosphorylation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Loss of centrosome integrity induces p38-p53-p21-dependent G1-S arrest

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Bone marrow failure in Fanconi anemia is triggered by an exacerbated p53/p21 DNA damage response that impairs hematopoietic stem and progenitor cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Spontaneous abrogation of the G₂DNA damage checkpoint has clinical benefits but promotes leukemogenesis in Fanconi anemia patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Fanconi anemia type C and p53 cooperate in apoptosis and tumorigenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Myelodysplasia and leukemia of Fanconi anemia are associated with a specific pattern of genomic abnormalities that includes cryptic RUNX1/AML1 lesions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Fanconi anemia C gene product regulates expression of genes involved in differentiation and inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

TNF-alpha induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

TNF-α signaling in Fanconi anemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Immune defects in Fanconi anemia.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Oxidative stress: a concept in redox biology and medicine

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Modulation of oxidative stress as an anticancer strategy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

An overview of the chemistry and biology of reactive aldehydes.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Evidence of mitochondrial dysfunction and impaired ROS detoxifying machinery in Fanconi anemia cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Carcinogenicity of alcoholic beverages

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

DNA and protein adducts in human tissues resulting from exposure to tobacco smoke

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

ALDH2 polymorphism and alcohol-related cancers in Asians: a public health perspective

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Possible role of liver cytosolic and mitochondrial aldehyde dehydrogenases in acetaldehyde metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

The alcohol flushing response: an unrecognized risk factor for esophageal cancer from alcohol consumption

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Aldehyde dehydrogenase deficiency as cause of facial flushing reaction to alcohol in Japanese

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Oxygen-dependence of chromosomal aberrations in Fanconi's anaemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Bone marrow cell transcripts from Fanconi anaemia patients reveal in vivo alterations in mitochondrial, redox and DNA repair pathways.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

The FA pathway counteracts oxidative stress through selective protection of antioxidant defense gene promoters

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Defective mitochondrial peroxiredoxin-3 results in sensitivity to oxidative stress in Fanconi anemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Oxidant hypersensitivity of Fanconi anemia type C-deficient cells is dependent on a redox-regulated apoptotic pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Oxidative stress causes telomere damage in Fanconi anaemia cells - a possible predisposition for malignant transformation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Hyperbaric oxygen treatment decreases inflammation and mechanical hypersensitivity in an animal model of inflammatory pain.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Defective hematopoiesis and hepatic steatosis in mice with combined deficiencies of the genes encoding Fancc and Cu/Zn superoxide dismutase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Maternal aldehyde elimination during pregnancy preserves the fetal genome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Endogenous Formaldehyde Is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Variant ALDH2 is associated with accelerated progression of bone marrow failure in Japanese Fanconi anemia patients.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Acetaldehyde and the genome: beyond nuclear DNA adducts and carcinogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Fancd2-/- mice have hematopoietic defects that can be partially corrected by resveratrol.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Evaluation of resveratrol and N-acetylcysteine for cancer chemoprevention in a Fanconi anemia murine model.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Calcitriol for Oral Mucositis Prevention in Patients With Fanconi Anemia Undergoing Hematopoietic SCT: A Double-Blind, Randomized, Placebo-Controlled Trial

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Application of Bioactive Quercetin in Oncotherapy: From Nutrition to Nanomedicine

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Flavonoids as Cytokine Modulators: A Possible Therapy for Inflammation-Related Diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

PARP inhibitors: Synthetic lethality in the clinic

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

CHK1 inhibition as a strategy for targeting Fanconi Anemia (FA) DNA repair pathway deficient tumors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Olaparib monotherapy in patients with advanced cancer and a germline BRCA1/2 mutation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

FDA Approval Summary: Olaparib Monotherapy in Patients with Deleterious Germline BRCA-Mutated Advanced Ovarian Cancer Treated with Three or More Lines of Chemotherapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Gene expression profile of BRCAness that correlates with responsiveness to chemotherapy and with outcome in patients with epithelial ovarian cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: a preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Olaparib Maintenance Therapy in Platinum-Sensitive Relapsed Ovarian Cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Olaparib tablets as maintenance therapy in patients with platinum-sensitive, relapsed ovarian cancer and a BRCA1/2 mutation (SOLO2/ENGOT-Ov21): a double-blind, randomised, placebo-controlled, phase 3 trial

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

FANCD2 re-expression is associated with glioma grade and chemical inhibition of the Fanconi Anaemia pathway sensitises gliomas to chemotherapeutic agents.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Chemosensitization to cisplatin by inhibitors of the Fanconi anemia/BRCA pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Monoketone analogs of curcumin, a new class of Fanconi anemia pathway inhibitors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Fanconi anemia and solid malignancies in childhood: a national retrospective study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Biallelic FANCD1/BRCA2 mutations predisposing to glioblastoma multiforme with multiple oncogenic amplifications

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Association of biallelic BRCA2/FANCD1 mutations with spontaneous chromosomal instability and solid tumors of childhood

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Germline mutations in BRCA2: shared genetic susceptibility to breast cancer, early onset leukemia, and Fanconi anemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Mouse models of Fanconi anemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Leukemia and chromosomal instability in aged Fancc-/- mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Phosphorylation of fanconi anemia (FA) complementation group G protein, FANCG, at serine 7 is important for function of the FA pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Several tetratricopeptide repeat (TPR) motifs of FANCG are required for assembly of the BRCA2/D1-D2-G-X3 complex, FANCD2 monoubiquitylation and phleomycin resistance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Phosphorylation of FANCD2 on two novel sites is required for mitomycin C resistance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

ATR couples FANCD2 monoubiquitination to the DNA-damage response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Fanconi anemia complementation group FANCD2 protein serine 331 phosphorylation is important for fanconi anemia pathway function and BRCA2 interaction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

A novel ubiquitin ligase is deficient in Fanconi anemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

The structure of the catalytic subunit FANCL of the Fanconi anemia core complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

UBE2T is the E2 in the Fanconi anemia pathway and undergoes negative autoregulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Mutations in the gene encoding the E2 conjugating enzyme UBE2T cause Fanconi anemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Deficiency of UBE2T, the E2 Ubiquitin Ligase Necessary for FANCD2 and FANCI Ubiquitination, Causes FA-T Subtype of Fanconi Anemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Ubiquitin-SUMO circuitry controls activated fanconi anemia ID complex dosage in response to DNA damage

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Inactivation of murine Usp1 results in genomic instability and a Fanconi anemia phenotype.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Hematopoietic stem cell defects in mice with deficiency of Fancd2 or Usp1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

A selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responses.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Fanconi anemia: a model disease for studies on human genetics and advanced therapeutics

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Biallelic inactivation of REV7 is associated with Fanconi anemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Draft consensus guidelines for diagnosis and treatment of Shwachman-Diamond syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

The short and long telomere syndromes: paired paradigms for molecular medicine

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

Mutated Fanconi anemia pathway in non-Fanconi anemia cancers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC.2017.116

7 January 2021

inferred from DOI database lookup

Multiple phosphorylation of stathmin. Identification of four sites phosphorylated in intact cells and in vitro by cyclic AMP-dependent protein kinase and p34cdc2

1 reference

12 December 2020

In vitro hypersensitivity to oxygen of Fanconi anemia (FA) cells is linked to ex vivo evidence for oxidative stress in FA homozygotes and heterozygotes

1 reference

12 December 2020

Inactivation of the Fanconi anemia group C gene augments interferon-gamma-induced apoptotic responses in hematopoietic cells

1 reference

12 December 2020

The Fanconi anemia polypeptide, FAC, binds to the cyclin-dependent kinase, cdc2

1 reference

12 December 2020

Multiple inhibitory cytokines induce deregulated progenitor growth and apoptosis in hematopoietic cells from Fac-/- mice.

1 reference

12 December 2020

The IVS4 + 4 A to T mutation of the fanconi anemia gene FANCC is not associated with a severe phenotype in Japanese patients

1 reference

12 December 2020

Association of complementation group and mutation type with clinical outcome in fanconi anemia. European Fanconi Anemia Research Group

1 reference

12 December 2020

Interferon-gamma-induced apoptotic responses of Fanconi anemia group C hematopoietic progenitor cells involve caspase 8-dependent activation of caspase 3 family members.

1 reference

12 December 2020

Aberrant Fanconi anaemia protein profiles in acute myeloid leukaemia cells

1 reference

12 December 2020

Fanconi anemia gene mutations in young-onset pancreatic cancer

1 reference

12 December 2020

Germ line Fanconi anemia complementation group C mutations and pancreatic cancer

1 reference

12 December 2020

Hypermethylation of the FANCC and FANCL promoter regions in sporadic acute leukaemia.

1 reference

12 December 2020

BRCA2 heterozygosity delays cytokinesis in primary human fibroblasts.

1 reference

12 December 2020

Malignancies and survival patterns in the National Cancer Institute inherited bone marrow failure syndromes cohort study.

1 reference

12 December 2020

Acute myeloid leukemia with complex hypodiploidy and loss of heterozygosity of 17p in a boy with Fanconi anemia

1 reference

12 December 2020

VACTERL-H Association and Fanconi Anemia

1 reference

12 December 2020

Revisiting the hallmarks of cancer

1 reference

12 December 2020