Glucuronidation of Etoposide in Human Liver Microsomes Is Specifically Catalyzed by UDP-Glucuronosyltransferase 1A1 (Q44403623)

https://api.crossref.org/works/10.1124/DMD.31.5.589

2 December 2017

title

Glucuronidation of Etoposide in Human Liver Microsomes Is Specifically Catalyzed by UDP-Glucuronosyltransferase 1A1 (English)

1 reference

24 December 2023

1 reference

pharmaceutical science

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.589

24 December 2023

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.589

24 December 2023

Yuichiro Watanabe

1 reference

2 December 2017

Miki Nakajima

1 reference

2 December 2017

Noriko Ohashi

1 reference

2 December 2017

Toshiyuki Kume

1 reference

2 December 2017

Tsuyoshi Yokoi

1 reference

2 December 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12695347

reference URL

24 December 2023

publication date

1 May 2003

1 reference

full work available at URL

2 December 2017

https://syndication.highwire.org/content/doi/10.1124/dmd.31.5.589

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.589

Drug Metabolism and Disposition

24 December 2023

published in

1 reference

2 December 2017

1 reference

2 December 2017

1 reference

2 December 2017

page(s)

589-595

1 reference

The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome

2 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.589

The clinical pharmacology of etoposide and teniposide

24 December 2023

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.589

Metabolic studies of a podophyllotoxin derivative (VP16) in the isolated perfused liver

24 December 2023

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.589

The role of hepatic and extrahepatic UDP-glucuronosyltransferases in human drug metabolism

24 December 2023

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.589

Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus

24 December 2023

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.589

Identification of etoposide glucuronide as a major metabolite of etoposide in the rat and rabbit.

24 December 2023

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.589

Determination of UDP-glucuronosyltransferase UGT1A6 activity in human and rat liver microsomes by HPLC with UV detection

24 December 2023

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.589

Human liver UDP-glucuronosyltransferase isoforms involved in the glucuronidation of 7-ethyl-10-hydroxycamptothecin

24 December 2023

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.589

Pharmacokinetics of high dose etoposide (VP 16-213)

24 December 2023

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.589

Predicting etoposide toxicity: relationship to organ function and protein binding

24 December 2023

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.589

The glucuronidation of exogenous and endogenous compounds by stably expressed rat and human UDP-glucuronosyltransferase 1.1

24 December 2023

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.589

Protein measurement with the Folin phenol reagent

24 December 2023

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.589

The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence

24 December 2023

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.589

Drug glucuronidation in humans

24 December 2023

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.589

Genetic variation in bilirubin UPD-glucuronosyltransferase gene promoter and Gilbert's syndrome

24 December 2023

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.589

Involvement of multiple UDP-glucuronosyltransferase 1A isoforms in glucuronidation of 5-(4'-hydroxyphenyl)-5-phenylhydantoin in human liver microsomes

24 December 2023

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.589

Etoposide (VP-16-213). Current status of an active anticancer drug

24 December 2023

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.589

O-demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4.

24 December 2023

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.589

Roles of glucuronidation and UDP-glucuronosyltransferases in xenobiotic bioactivation reactions

24 December 2023

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.589

Genetic defect of bilirubin UDP-glucuronosyltransferase in the hyperbilirubinemic Gunn rat

24 December 2023

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.589

Use of etoposide in patients with organ dysfunction: pharmacokinetic and pharmacodynamic considerations

24 December 2023

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.589

Human UDP-glucuronosyltransferases: metabolism, expression, and disease

24 December 2023

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.589

Troglitazone glucuronidation in human liver and intestine microsomes: high catalytic activity of UGT1A8 and UGT1A10.

24 December 2023

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.589

Contribution of two missense mutations (G71R and Y486D) of the bilirubin UDP glycosyltransferase (UGT1A1) gene to phenotypes of Gilbert's syndrome and Crigler-Najjar syndrome type II

24 December 2023

1 reference

https://api.crossref.org/works/10.1124/DMD.31.5.589

24 December 2023

Identifiers

DOI

10.1124/DMD.31.5.589

1 reference

2 December 2017

1 reference