Phosphorylation of tyrosine residues 31 and 118 on paxillin regulates cell migration through an association with CRK in NBT-II cells (Q30175229)

13 August 2017

Phosphorylation of tyrosine residues 31 and 118 on paxillin regulates cell migration through an association with CRK in NBT-II cells (English)

1 reference

13 August 2017

1 reference

1 reference

V Petit

1 reference

13 August 2017

B Boyer

1 reference

13 August 2017

D Lentz

1 reference

13 August 2017

C E Turner

1 reference

13 August 2017

J P Thiery

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13 August 2017

A M Vallés

1 reference

13 August 2017

language of work or name

English

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publication date

1 March 2000

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13 August 2017

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inferred from page(s)

published in

Journal of Cell Biology

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13 August 2017

148

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13 August 2017

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13 August 2017

957-970

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Characterization of the signaling pathways regulating alpha2beta1 integrin-mediated events by a pharmacological approach

13 August 2017

1 reference

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Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling

3 June 2018

1 reference

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Bidirectional signaling between the cytoskeleton and integrins

3 June 2018

1 reference

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Protein tyrosine phosphatase-PEST regulates focal adhesion disassembly, migration, and cytokinesis in fibroblasts

3 June 2018

1 reference

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The functional role of CrkII in actin cytoskeleton organization and mitogenesis

3 June 2018

1 reference

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Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase

3 June 2018

1 reference

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Activation of Rac1 by a Crk SH3-binding protein, DOCK180

3 June 2018

1 reference

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3 June 2018

1 reference

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Evidence that DOCK180 up-regulates signals from the CrkII-p130(Cas) complex

3 June 2018

1 reference

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Insulin stimulates the tyrosine dephosphorylation of docking protein p130cas (Crk-associated substrate), promoting the switch of the adaptor protein crk from p130cas to newly phosphorylated insulin receptor substrate-1

3 June 2018

1 reference

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Integrins and GTPases in tumour cell growth, motility and invasion

3 June 2018

1 reference

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Protein-tyrosine phosphatase Shp-2 regulates cell spreading, migration, and focal adhesion

3 June 2018

1 reference

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3 June 2018

1 reference

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Serine and threonine phosphorylation of the paxillin LIM domains regulates paxillin focal adhesion localization and cell adhesion to fibronectin

3 June 2018

1 reference

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Integrins regulate the association and phosphorylation of paxillin by c-Abl

3 June 2018

1 reference

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CAS/Crk coupling serves as a "molecular switch" for induction of cell migration

3 June 2018

1 reference

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Association of Bovine Papillomavirus Type 1 E6 oncoprotein with the focal adhesion protein paxillin through a conserved protein interaction motif

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration

3 June 2018

1 reference

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Integrin-linked Protein Kinase Regulates Fibronectin Matrix Assembly, E-cadherin Expression, and Tumorigenicity

3 June 2018

1 reference

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BCR/ABL-induced leukemogenesis causes phosphorylation of Hef1 and its association with Crkl

3 June 2018

1 reference

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Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K

3 June 2018

1 reference

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Integrins, oncogenes, and anchorage independence.

3 June 2018

1 reference

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Integrin signaling: specificity and control of cell survival and cell cycle progression

3 June 2018

1 reference

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Src and Ras are involved in separate pathways in epithelial cell scattering

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

Bombesin stimulates the motility of human prostate-carcinoma cells through tyrosine phosphorylation of focal adhesion kinase and of integrin-associated proteins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

Adhesion of fibroblasts to fibronectin stimulates both serine and tyrosine phosphorylation of paxillin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

Model systems of epithelium-mesenchyme transitions

3 June 2018

1 reference

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Epithelial-mesenchymal transitions in cancer progression

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

The bovine papillomavirus E6 oncoprotein interacts with paxillin and disrupts the actin cytoskeleton.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

Signaling through focal adhesion kinase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

Transformation by Rho exchange factor oncogenes is mediated by activation of an integrin-dependent pathway

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

Focal adhesions, contractility, and signaling

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

Alpha 2 beta 1 integrin is required for the collagen and FGF-1 induced cell dispersion in a rat bladder carcinoma cell line.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

Identification of LIM3 as the principal determinant of paxillin focal adhesion localization and characterization of a novel motif on paxillin directing vinculin and focal adhesion kinase binding

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

Epithelio-mesenchymal transformation during formation of the mesoderm in the mammalian embryo.

3 June 2018

1 reference

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An overview of epithelio-mesenchymal transformation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

Networks of interaction of p120cbl and p130cas with Crk and Grb2 adaptor proteins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

The molecular architecture of focal adhesions

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

Integrin alphavbeta3 mediates chemotactic and haptotactic motility in human melanoma cells through different signaling pathways

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

Cell adhesion: the molecular basis of tissue architecture and morphogenesis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

Bombesin, vasopressin, and endothelin rapidly stimulate tyrosine phosphorylation of the focal adhesion-associated protein paxillin in Swiss 3T3 cells.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

Detection of Src homology 3-binding proteins, including paxillin, in normal and v-Src-transformed Balb/c 3T3 cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

Platelet-derived growth factor modulation of focal adhesion kinase (p125FAK) and paxillin tyrosine phosphorylation in Swiss 3T3 cells. Bell-shaped dose response and cross-talk with bombesin.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

The riddle of morphogenesis: a question of solution chemistry or molecular cell engineering?

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

CRK protein binds to two guanine nucleotide-releasing proteins for the Ras family and modulates nerve growth factor-induced activation of Ras in PC12 cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

Cytokine control of cell motility: modulation and mediation by the extracellular matrix

3 June 2018

1 reference

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Nerve growth factor triggers microfilament assembly and paxillin phosphorylation in human B lymphocytes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function.

3 June 2018

1 reference

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Evidence that SH2 domains promote processive phosphorylation by protein-tyrosine kinases

3 June 2018

1 reference

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Integrins and signal transduction pathways: the road taken

3 June 2018

1 reference

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Identification and Characterization of a High-Affinity Interaction Between v-Crk and Tyrosine-Phosphorylated Paxillin in CT10-Transformed Fibroblasts

3 June 2018

1 reference

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Structural requirement of CRK SH2 region for binding to phosphotyrosine-containing proteins. Evidence from reactivity to monoclonal antibodies

3 June 2018

1 reference

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Characterization of tyrosine phosphorylation of paxillin in vitro by focal adhesion kinase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

pp60c-src is a positive regulator of growth factor-induced cell scattering in a rat bladder carcinoma cell line

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

Integrin-mediated cell adhesion promotes tyrosine phosphorylation of p130Cas, a Src homology 3-containing molecule having multiple Src homology 2-binding motifs

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

Primary sequence of paxillin contains putative SH2 and SH3 domain binding motifs and multiple LIM domains: identification of a vinculin and pp125Fak-binding region

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

Analysis of the binding of the Src homology 2 domain of Csk to tyrosine-phosphorylated proteins in the suppression and mitotic activation of c-Src

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

CRKL links p210BCR/ABL with paxillin in chronic myelogenous leukemia cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

Tissue culture of urinary bladder tumor induced in a rat by N-butyl-N-(-4-hydroxybutyl)nitrosamine: establishment of cell line, Nara Bladder Tumor II

3 June 2018

1 reference

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Rearrangements of desmosomal and cytoskeletal proteins during the transition from epithelial to fibroblastoid organization in cultured rat bladder carcinoma cells

3 June 2018

1 reference

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Novel tyrosine kinase substrates from Rous sarcoma virus-transformed cells are present in the membrane skeleton

3 June 2018

1 reference

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Collagen-mediated dispersion of NBT-II rat bladder carcinoma cells.

3 June 2018

1 reference

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Paxillin: a new vinculin-binding protein present in focal adhesions

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

Alternative patterns of mitogenesis and cell scattering induced by acidic FGF as a function of cell density in a rat bladder carcinoma cell line

3 June 2018

1 reference

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SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins

3 June 2018

1 reference

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Integrins: versatility, modulation, and signaling in cell adhesion

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174549

Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly

3 June 2018

1 reference

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Possible v-Crk-induced transformation through activation of Src kinases.

3 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1083%2FJCB.148.5.957

Angiotensin II stimulation of rapid paxillin tyrosine phosphorylation correlates with the formation of focal adhesions in rat aortic smooth muscle cells

21 January 2018

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12 December 2020

Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn

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12 December 2020

Scatter factor/hepatocyte growth factor (SF/HGF) induces emigration of myogenic cells at interlimb level in vivo

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12 December 2020

Activation of the focal adhesion kinase signal transduction pathway in cervical carcinoma cell lines and human genital epithelial cells immortalized with human papillomavirus type 18

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12 December 2020

The bovine papillomavirus E6 protein binds to the LD motif repeats of paxillin and blocks its interaction with vinculin and the focal adhesion kinase

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.148.5.957

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

10704446

1 reference