The Contribution of Mosaic Variants to Autism Spectrum Disorder (Q36134616)

12 August 2017

The Contribution of Mosaic Variants to Autism Spectrum Disorder (English)

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12 August 2017

autism spectrum disorder

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Donald Freed

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12 August 2017

Jonathan Pevsner

series ordinal

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12 August 2017

15 September 2016

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12 August 2017

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12 August 2017

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12 August 2017

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12 August 2017

e1006245

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Creative Commons Attribution 4.0 International

12 August 2017

start time

15 September 2016

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April 2022 Public Data File from Crossref

copyrighted

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cites work

The landscape of somatic mutations in protein coding genes in apparently benign human tissues carries signatures of relaxed purifying selection

1 reference

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Post-zygotic Point Mutations Are an Underrecognized Source of De Novo Genomic Variation

2 October 2017

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Excess of rare, inherited truncating mutations in autism

2 October 2017

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Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence

2 October 2017

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Recurrent de novo mutations implicate novel genes underlying simplex autism risk

2 October 2017

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The contribution of de novo coding mutations to autism spectrum disorder

2 October 2017

1 reference

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Synaptic, transcriptional and chromatin genes disrupted in autism

2 October 2017

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Somatic mutations in cerebral cortical malformations

2 October 2017

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Genome sequencing identifies major causes of severe intellectual disability

2 October 2017

1 reference

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Somatic mutations found in the healthy blood compartment of a 115-yr-old woman demonstrate oligoclonal hematopoiesis

2 October 2017

1 reference

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Integrating human sequence data sets provides a resource of benchmark SNP and indel genotype calls

2 October 2017

1 reference

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The role of de novo mutations in the genetics of autism spectrum disorders

2 October 2017

1 reference

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Database resources of the National Center for Biotechnology Information

2 October 2017

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Somatic point mutations occurring early in development: a monozygotic twin study.

2 October 2017

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Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

2 October 2017

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Multiplex targeted sequencing identifies recurrently mutated genes in autism spectrum disorders

2 October 2017

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2 October 2017

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A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso-2; iso-3

2 October 2017

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Primer-BLAST: a tool to design target-specific primers for polymerase chain reaction

2 October 2017

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Strelka: accurate somatic small-variant calling from sequenced tumor-normal sample pairs

2 October 2017

1 reference

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De Novo Gene Disruptions in Children on the Autistic Spectrum

2 October 2017

1 reference

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Patterns and rates of exonic de novo mutations in autism spectrum disorders

2 October 2017

1 reference

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Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations

2 October 2017

1 reference

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De novo mutations revealed by whole-exome sequencing are strongly associated with autism

2 October 2017

1 reference

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Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism

2 October 2017

1 reference

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Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5024993

A framework for variation discovery and genotyping using next-generation DNA sequencing data

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5024993

The Simons Simplex Collection: A Resource for Identification of Autism Genetic Risk Factors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5024993

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

2 October 2017

1 reference

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Functional impact of global rare copy number variation in autism spectrum disorders

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5024993

BEDTools: a flexible suite of utilities for comparing genomic features

2 October 2017

1 reference

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The Sequence Alignment/Map format and SAMtools

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5024993

Fast and accurate short read alignment with Burrows-Wheeler transform

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5024993

Biopython: freely available Python tools for computational molecular biology and bioinformatics

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5024993

Structural variation of chromosomes in autism spectrum disorder

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5024993

A unified genetic theory for sporadic and inherited autism

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5024993

Strong association of de novo copy number mutations with autism

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5024993

The human genome browser at UCSC

2 October 2017

1 reference

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Lethal genes surviving by mosaicism: a possible explanation for sporadic birth defects involving the skin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5024993

Early postzygotic mutations contribute to de novo variation in a healthy monozygotic twin pair

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5024993

New Methods for Detecting Lineage-Specific Selection

23 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1006245

Analysis of protein-coding genetic variation in 60,706 humans

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27632392

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PGEN.1006245

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

27632392

1 reference