binimetinib (Q19903515)

Binimetinib (English)

3 October 2016

chemical formula

C₁₇H₁₅BrF₂N₄O₃

1 reference

Binimetinib (English)

3 October 2016

canonical SMILES

CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)F)C(=O)NOCCO

1 reference

Binimetinib (English)

World Health Organisation international non-proprietary name

3 October 2016

binimetinib (English)

1 reference

published in

Recommended INN: List 71

publication date

2014

medical condition treated

low-grade serous carcinoma

0 references

physically interacts with

Mitogen-activated protein kinase kinase 1

subject has role

allosteric modulator

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Mitogen-activated protein kinase kinase 2

17 August 2016

subject has role

allosteric modulator

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Mitogen-activated protein kinase kinase 1

17 August 2016

subject has role

reaction inhibitor

1 reference

Open Targets Platform

https://platform.opentargets.org/drug/CHEMBL3187723

14 August 2023

reference URL

Commons category

Binimetinib

0 references

Identifiers

InChI

InChI=1S/C17H15BrF2N4O3/c1-24-8-21-16-13(24)7-10(17(26)23-27-5-4-25)15(14(16)20)22-12-3-2-9(18)6-11(12)19/h2-3,6-8,22,25H,4-5H2,1H3,(H,23,26)

1 reference

Binimetinib (English)

3 October 2016

1 reference

Global Substance Registration System

Binimetinib (English)

3 October 2016

2 references

UNII

181R97MR71

BINIMETINIB (English)

3 October 2016

https://commonchemistry.cas.org/detail?cas_rn=606143-89-9

10 April 2021

1 reference

Binimetinib (English)

3 October 2016

2 references

Binimetinib (English)

3 October 2016

ChEBI ID

145371

mapping relation type

exact match

2 references

ChEBI release 2021-03-01

International Chemical Identifier

InChI

InChI=1S/C17H15BrF2N4O3/c1-24-8-21-16-13(24)7-10(17(26)23-27-5-4-25)15(14(16)20)22-12-3-2-9(18)6-11(12)19/h2-3,6-8,22,25H,4-5H2,1H3,(H,23,26)

1 reference

BINIMETINIB (English)

3 October 2016

2 references

inferred from InChIKey

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

1 reference

2 references

DSSTOX compound identifier

0 references

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.167.617

27 December 2018

ECHA Substance Infocard ID

1H-Benzimidazole-6-carboxamide, 5-[(4-bromo-2-fluorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl- (English)

quotation

CAS no.: 606143-89-9 (English)

100.167.617

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.167.617

27 December 2018

World Health Organisation international non-proprietary name numeric ID

1H-Benzimidazole-6-carboxamide, 5-[(4-bromo-2-fluorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl- (English)

quotation

CAS no.: 606143-89-9 (English)

ATC code

L01XE41

0 references

9764

1 reference

reference URL

https://mednet-communities.net/inn/db/ViewINN.aspx?i=9764

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

binimetinib (English)

3 October 2016

0 references

1 reference

Human Metabolome Database ID

HMDB0304890

2 references

based on heuristic

inferred from InChIKey

UNII

181R97MR71

2 references

Global Substance Registration System

UNII

181R97MR71

BINIMETINIB (English)

3 October 2016