Suppressor of cytokine signaling 4 (Q21172876)

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mammalian protein found in Homo sapiens

• suppressor of cytokine signaling 4
• SOCS4
• suppressor of cytokine signaling 7
• SOCS-7
• SOCS-4
• SH2 domain containing SOCS box protein

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Language	Label	Description	Also known as
English	Suppressor of cytokine signaling 4	mammalian protein found in Homo sapiens	suppressor of cytokine signaling 4 SOCS4 suppressor of cytokine signaling 7 SOCS-7 SOCS-4 SH2 domain containing SOCS box protein

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q8WXH5

subclass of

protein

1 reference

stated in

UniProt

retrieved

1 December 2016

UniProt protein ID

Q8WXH5

part of

Suppressor of cytokine signalling 4

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8WXH5

SOCS box-like domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8WXH5

SH2 domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8WXH5

SH2 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SOCS4, SH2 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SOCS4, SOCS box domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SOCS4/SOCS5 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SOCS box domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q8WXH5

encoded by

SOCS4

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q8WXH5

molecular function

protein kinase inhibitor activity

determination method or standard

IBA

1 reference

retrieved

27 March 2018

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WXH5&geneProductId=UniProtKB:Q8WXH5

determination method or standard

IBA

protein binding

determination method or standard

IPI

1 reference

retrieved

8 April 2019

stated in

Phospho-tyrosine dependent protein-protein interaction network

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXH5

determination method or standard

IPI

cell component

cytoplasm

determination method or standard

IBA

1 reference

retrieved

27 March 2018

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WXH5&geneProductId=UniProtKB:Q8WXH5

determination method or standard

IBA

intracellular anatomical structure

determination method or standard

IEA

1 reference

retrieved

10 September 2018

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WXH5&geneProductId=UniProtKB:Q8WXH5

determination method or standard

IEA

biological process

negative regulation of epidermal growth factor-activated receptor activity

determination method or standard

IDA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXH5

determination method or standard

IEA

retrieved

8 April 2019

stated in

Suppressors of cytokine signaling 4 and 5 regulate epidermal growth factor receptor signaling

GOA

curator

UniProt

UniProt protein ID

Q8WXH5

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXH5

determination method or standard

IDA

regulation of growth

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8WXH5

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXH5

determination method or standard

IEA

negative regulation of signal transduction

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8WXH5

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXH5

determination method or standard

IEA

intracellular signal transduction

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXH5

determination method or standard

IEA

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXH5

determination method or standard

IEA

protein ubiquitination

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8WXH5

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXH5

determination method or standard

IEA

cytokine-mediated signaling pathway

determination method or standard

IBA

1 reference

retrieved

27 March 2018

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WXH5&geneProductId=UniProtKB:Q8WXH5

determination method or standard

IBA

negative regulation of receptor signaling pathway via JAK-STAT

determination method or standard

IBA

1 reference

retrieved

27 March 2018

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WXH5&geneProductId=UniProtKB:Q8WXH5

determination method or standard

IBA

has part(s)

SOCS box domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8WXH5

SH2 domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8WXH5

SOCS4/SOCS5 domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8WXH5

SOCS4, SH2 domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8WXH5

SOCS4, SOCS box domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8WXH5

Identifiers

RefSeq protein ID

NP_543143

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

122809

NP_955453

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

122809

XP_011534727

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

122809

XP_011534728

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

122809

UniProt protein ID

Q8WXH5

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q8WXH5

Ensembl protein ID

ENSP00000341327

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000341327

ENSP00000378855

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000378855

ENSP00000452522

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000452522

PDB structure ID

2IZV

1 reference

stated in

UniProt

UniProt protein ID

Q8WXH5

retrieved

20 March 2016

language of work or name

English

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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