This document summarizes information about zinc, including its dietary sources, recommended daily allowances, physiological functions, deficiency, and treatment. Some key points include:
- Zinc is an essential micronutrient found in high amounts in oysters, meat, and nuts. It plays roles in over 300 enzymes and 2000 transcription factors.
- Recommended daily zinc intake ranges from 2-11 mg per day depending on age. Pregnant and lactating women should have 11-12 mg.
- Zinc deficiency can cause impaired immunity, growth retardation, skin disorders, and is common in developing countries. It is diagnosed through blood tests.
- Treatment involves oral zinc supplementation, with doses ranging from 0.
The document discusses the refining and purification process of zinc. It begins with an introduction to zinc including its chemical formula, atomic number, and color. It then discusses the history of zinc discovery and production. The main uses of zinc are then outlined, followed by global zinc production and reserve statistics. The key steps in the zinc refining and purification process are then described in detail, including roasting, leaching, purification, electrolysis, melting and casting. Gas cleaning and sulfuric acid production are also summarized. Finally, the main applications of zinc in automotive, construction, hot dip galvanizing, and zinc castings are briefly outlined.
The document discusses the biological functions of zinc. It begins with an introduction to zinc, including its history of use in ancient India and its discovery in 1746. The document then outlines topics to be covered, including sources of zinc, requirements and homeostasis, deficiency and toxicity, biochemical and molecular functions, and immunological and endocrinological roles. It proceeds to cover these topics in depth over several slides, focusing on zinc absorption, transport, regulation, storage, and distribution within the body and cells.
Zinc is an essential mineral that is vital for many bodily functions. It is found naturally in many foods and is also used industrially and medically. Zinc deficiency can cause numerous health issues, while excess zinc consumption can also be toxic. The document discusses zinc's properties, roles in the body, dietary sources, causes and effects of deficiency, diagnosis of deficiency, treatments for deficiency and toxicity, and other clinical uses of zinc supplements.
The document discusses extractive metallurgy processes for zinc extraction. It describes the major zinc ores and details several pyrometallurgical and hydrometallurgical extraction processes. The key processes are roasting to produce zinc oxide from zinc sulfide ores, followed by leaching and electrolysis to recover zinc. Approximately 80% of zinc is produced via hydrometallurgical routes like roast-leach-electrowinning.
El documento proporciona información sobre las propiedades y funciones del zinc. Explica que el zinc es un metal de transición esencial para la salud humana. Se encuentra naturalmente en los alimentos y desempeña un papel importante en más de 300 enzimas y 3000 proteínas del cuerpo. La deficiencia de zinc puede provocar retraso en el crecimiento, alteraciones óseas y dermatitis, entre otros problemas. Industrialmente, el zinc se usa principalmente para proteger otros metales de la corrosión.
1) Aproximadamente 1/3 de la población mundial vive en países con deficiencia de zinc. 2) El 82% de las mujeres embarazadas en todo el mundo tienen un consumo inadecuado de zinc. 3) La deficiencia de zinc causa casi el 4% de las muertes y años de vida ajustados por discapacidad en niños menores de 5 años en países de bajos ingresos.
The document discusses zinc extraction processes. There are two main categories of processes: pyrometallurgical and hydrometallurgical. Approximately 80% of the world's zinc is produced via hydrometallurgical processes like the roast-leach-electrowin process. This process involves roasting zinc sulfide concentrate to produce zinc oxide, which is then leached and electrowon to extract zinc metal. An alternative is the pressure leach process, which combines roasting and leaching into a single step to produce zinc sulfate solution for electrowinning.
Zinc is a micronutrient that is essential for cellular metabolism and the function of over 100 enzymes. It is absorbed in the small intestine and transported to tissues like the liver and blood cells. Zinc is lost from the body primarily through gastrointestinal excretion and helps control hormone release and nerve signaling. Zinc deficiency can cause growth retardation and skin disorders, while adequate zinc supports immune function and reduces the duration of diarrhea. Therapeutically, zinc treatment has proven highly effective for decreasing the occurrence of prolonged childhood diarrhea in developing countries.
El zinc es un metal blanco azulado que se encuentra ampliamente en la naturaleza. Tiene propiedades como buena conductividad eléctrica y térmica, y punto de fusión y ebullición elevados. Se utiliza principalmente para galvanizar el acero y prevenir la corrosión, y también en aleaciones como el latón. Otras aplicaciones incluyen pigmentos, baterías, monedas, fungicidas y suplementos dietéticos debido a sus propiedades antimicrobianas.
Zinc is an essential micronutrient for plant growth. It plays important roles in carbohydrate metabolism, protein metabolism, and membrane integrity. Zinc deficiency can lead to chlorosis, necrosis, reduced growth and yield losses. Factors like high soil pH, phosphorus application, and liming can reduce zinc availability. Deficiency symptoms vary by crop but include interveinal chlorosis, small leaves, and premature leaf drop. Soil and foliar zinc application can increase dry matter production, grain yield, harvest index and zinc content of crops.
El documento describe los usos del zinc en la industria y la medicina. El zinc se utiliza en baterías, aleaciones metálicas, pinturas y fabricación de latón. También desempeña un papel importante en los organismos vivos y en procesos como la galvanización del acero. Sin embargo, con el tiempo pueden formarse "bigotes de cinc" en el acero galvanizado que pueden causar cortocircuitos.
This document discusses vitamins, minerals, and water. It explains that vitamins and minerals regulate body functions and must be ingested daily through foods like fruits, vegetables, and whole grains. Dark leafy greens contain the most vitamins and minerals. Water carries nutrients through the body, regulates temperature, and prevents dehydration. We should drink half our body weight in ounces of water daily. The document then provides details on specific vitamins (A, D, E, K, C, B vitamins) and minerals, their functions, sources, deficiencies, and toxicities.
This document provides an overview of an internship presentation at Hindustan Zinc Smelter Ltd. in Debari, Udaipur. It introduces the company and describes the key processes involved in zinc production including acid and roaster plants, leaching and purification, electrolysis, and melting and casting. It also summarizes the intern's project studying the operation and maintenance of the acid-roaster plant, outlining the basic processes within the plant such as roasting, gas cleaning, and sulfuric acid production.
Zinc is a trace mineral that is important for many functions in the body. The total body content of zinc is about 2 grams, with high concentrations found in the prostate gland, muscle tissue, and bone. Good dietary sources of zinc include meat, dairy products, legumes, nuts, and spinach. Zinc is required for the function of many enzymes and is involved in processes like DNA synthesis, wound healing, growth, and taste sensation. Zinc deficiency can result in issues like hypogonadism, growth failure, and skin lesions. Toxicity from excess zinc intake is rare but can cause nausea and gastrointestinal issues.
Este documento presenta información sobre las aleaciones de zinc, incluyendo sus propiedades, usos comunes y efectos de los elementos de aleación. Discute las aleaciones de zinc-aluminio usadas para moldeo y las aleaciones de zinc-plomo, zinc-cobre y zinc-magnesio usadas para forja. También cubre las ventajas y desventajas de las aleaciones de zinc, así como sus aplicaciones y limitaciones.
Metabolism of zinc and its clinical significancerohini sane
A comprehensive presentation on Metabolism of Zinc and its clinical significance for MBBS,BDS,B.Tech,B.Pharma and Biotechnology students for self-study.
Mineral metabolism (iodine & zinc) -Biochemistryautumnpianist
1) The document discusses mineral metabolism, focusing on iodine and zinc. Iodine is important for thyroid hormone production and zinc serves as a cofactor for many enzymes.
2) Iodine is obtained from foods like seafood, fish, and iodized salt. The thyroid gland concentrates iodine and uses it to produce the hormones thyroxine and triiodothyronine. Iodine deficiency can cause goiter and hypothyroidism.
3) Zinc is found in foods like legumes, potatoes, and cabbage. It is a cofactor for over 300 enzymes and is important for processes like wound healing. Zinc deficiency can impair growth and immune function.
The document discusses the evidence for using zinc supplementation in the treatment of childhood diarrhea. Zinc supplementation is now recommended as part of the global diarrhea treatment strategy based on multiple clinical trials showing it reduces diarrhea duration and severity. Zinc addresses diarrhea by maintaining gut integrity and functioning of the immune system. Proper dosage and duration of zinc treatment is important to gain its protective benefits against future diarrhea episodes. Ensuring widespread access to affordable zinc formulations is now a priority in developing countries.
Zinc is one of the strategic non-ferrous metal next only to Aluminium and Copper. It plays a very important role in country’s economy and development. It finds use in applications like galvanizing of iron and steel; die-casting alloys, brasses, dry cells, agriculture, chemicals, pharmaceuticals etc., with industrial development in India use of zinc has increased considerably, however, specific consumption is much lower as compared to other developing countries.
The most important raw material for the production of zinc is the sulphide ore from which zinc is extracted either through pyro-metallurgical route or through hydro metallurgical – Roast – Leach – Electrowin (RLE) route. At present nearly 80 - 85% of the world’s production of primary zinc is through hydrometallurgical route, the balance is through pyro – metallurgical route.
Zinc’s largest use is in corrosion protection. Galvanising is the main method of protection against corrosion of steel, i.e. the steel is coated with a layer of zinc in order to protect it from decay.
Brasses are alloys of copper and zinc, and they have good mechanical properties and good corrosion resistance.
Diecastings are precision castings that can be mass-produced. Rolled zinc is used for architectural and building applications, and for dry cell batteries. Zinc oxide has its main use in tyres and rubber products. Many other zinc chemicals are used in a wide range of applications.
This document discusses vitamin and mineral deficiencies. It describes the fat-soluble and water-soluble vitamins, how deficiencies can be primary or secondary, and provides details on specific vitamin deficiencies like vitamins A, D, and C. Vitamin A deficiency can cause night blindness and xerophthalmia. Vitamin D deficiency results in rickets in children and osteomalacia in adults. Scurvy is caused by vitamin C deficiency and is characterized by bone disease and hemorrhages.
Hindustan Zinc Limited operates zinc, lead and silver mines and smelting facilities in India. It produces zinc, lead, silver and sulfuric acid. The document discusses Hindustan Zinc's hydrometallurgical plant processes which involve roasting zinc sulfide ore to produce zinc oxide, leaching the zinc oxide in sulfuric acid to produce zinc sulfate, and electrolysis in a cell house to electrowin zinc from the zinc sulfate solution. It also summarizes three student projects on pneumatic conveying of zinc dust, installation of rotary control valves for material handling, and development of air conditioning for a crane cabin.
This document provides a summary report of a 15-day summer training program at a Hindustan Zinc Limited Captive Power Plant. It discusses the key components and processes involved in generating electricity from coal at a thermal power plant, including the boiler, turbine, condenser, and feed pump. The report also provides overviews of the coal handling process, basic instrumentation systems, programmable logic controllers, and concludes with references.
The document summarizes the key stages of hydrometallurgical processes. It discusses three main stages: leaching, solution concentration and purification, and metal recovery. Leaching involves dissolving metals from ores using techniques like heap, vat, or agitation leaching. Solution concentration and purification removes impurities. Metal recovery precipitates metals from the solution chemically or electrochemically, such as via electrowinning. Hydrometallurgy is more environmentally friendly than pyrometallurgy and can process lower grade ores, but requires more time and has challenges with separation and impurities.
Zinc plays an important role in immunity and diarrhea. Zinc deficiency is common in acute and chronic diarrhea and leads to impaired immune function. Studies show that zinc supplementation in children with diarrhea reduces duration and severity of diarrhea episodes. It does so by accelerating regeneration of the intestinal mucosa and enhancing cellular immunity. As zinc deficiency is prevalent in developing countries, zinc supplements can be useful as both a preventive and therapeutic intervention for diarrhea.
Trace minerals are needed in small amounts but are essential for many bodily functions. They include iron, zinc, iodine, selenium, fluoride, manganese, molybdenum, chromium, and others. Trace mineral deficiencies can impair growth, development, immunity and cognitive function, while toxicities of some like iron, fluoride, and iodine can also negatively impact health. Food content of trace minerals depends on soil mineral content where the food was grown.
“Pharmacology of Aminoglycosides: A Detailed Review for Medical and Pharmacy ...Dr. NIDHI SRIVASTAVA
Aminoglycosides are a powerful class of antibiotics known for their rapid bactericidal action against serious Gram-negative infections. This presentation offers a comprehensive yet engaging exploration of their pharmacology, tailored specifically for medical, dental, and pharmacy students preparing for exams or looking to strengthen their clinical foundation.
We begin with the fascinating history of aminoglycosides, from the discovery of streptomycin in the 1940s to the development of newer agents like amikacin and netilmicin. These drugs are natural or semi-synthetic derivatives of Streptomyces and Micromonospora species and have saved countless lives, especially in critical care settings.
You’ll then dive into their mechanism of action, where aminoglycosides irreversibly bind to the 30S ribosomal subunit, causing mRNA misreading and inhibition of bacterial protein synthesis. Unlike most protein synthesis inhibitors, aminoglycosides are bactericidal—a unique trait that makes them especially valuable in treating life-threatening infections.
Their entry into bacterial cells depends on oxygen and energy, which explains why they are ineffective against anaerobes and are often used in combination with beta-lactam antibiotics. This synergy enhances bacterial cell wall permeability, increasing aminoglycoside uptake and efficacy.
The presentation clearly outlines the spectrum of activity—highlighting their strong effectiveness against aerobic Gram-negative bacilli like E. coli, Pseudomonas, and Klebsiella. For certain Gram-positive infections (e.g., Enterococcus, Staphylococcus), aminoglycosides serve as part of combination therapy.
Each major aminoglycoside—gentamicin, tobramycin, amikacin, streptomycin, and kanamycin—is covered in terms of pharmacokinetics, dosing, and clinical use. We also discuss newer uses, such as inhaled tobramycin in cystic fibrosis and amikacin against multi-drug-resistant tuberculosis.
Safety is a key part of this review. Students will understand the mechanisms behind nephrotoxicity, ototoxicity, and neuromuscular blockade, with tips on how to monitor and minimize these risks in clinical practice. Therapeutic drug monitoring (TDM) and once-daily dosing strategies are also explained, reflecting current guidelines.
We also explore mechanisms of resistance—from modifying enzymes to ribosomal mutations and decreased permeability—and what this means for treatment choices in the age of antimicrobial resistance.
This presentation aims to balance core pharmacological concepts with clinical relevance. Whether you’re preparing for exams, giving a seminar, or revising for practicals, this visually rich and well-organized resource will enhance your understanding of aminoglycosides and their role in modern medicine.
Zinc is a micronutrient that is essential for cellular metabolism and the function of over 100 enzymes. It is absorbed in the small intestine and transported to tissues like the liver and blood cells. Zinc is lost from the body primarily through gastrointestinal excretion and helps control hormone release and nerve signaling. Zinc deficiency can cause growth retardation and skin disorders, while adequate zinc supports immune function and reduces the duration of diarrhea. Therapeutically, zinc treatment has proven highly effective for decreasing the occurrence of prolonged childhood diarrhea in developing countries.
El zinc es un metal blanco azulado que se encuentra ampliamente en la naturaleza. Tiene propiedades como buena conductividad eléctrica y térmica, y punto de fusión y ebullición elevados. Se utiliza principalmente para galvanizar el acero y prevenir la corrosión, y también en aleaciones como el latón. Otras aplicaciones incluyen pigmentos, baterías, monedas, fungicidas y suplementos dietéticos debido a sus propiedades antimicrobianas.
Zinc is an essential micronutrient for plant growth. It plays important roles in carbohydrate metabolism, protein metabolism, and membrane integrity. Zinc deficiency can lead to chlorosis, necrosis, reduced growth and yield losses. Factors like high soil pH, phosphorus application, and liming can reduce zinc availability. Deficiency symptoms vary by crop but include interveinal chlorosis, small leaves, and premature leaf drop. Soil and foliar zinc application can increase dry matter production, grain yield, harvest index and zinc content of crops.
El documento describe los usos del zinc en la industria y la medicina. El zinc se utiliza en baterías, aleaciones metálicas, pinturas y fabricación de latón. También desempeña un papel importante en los organismos vivos y en procesos como la galvanización del acero. Sin embargo, con el tiempo pueden formarse "bigotes de cinc" en el acero galvanizado que pueden causar cortocircuitos.
This document discusses vitamins, minerals, and water. It explains that vitamins and minerals regulate body functions and must be ingested daily through foods like fruits, vegetables, and whole grains. Dark leafy greens contain the most vitamins and minerals. Water carries nutrients through the body, regulates temperature, and prevents dehydration. We should drink half our body weight in ounces of water daily. The document then provides details on specific vitamins (A, D, E, K, C, B vitamins) and minerals, their functions, sources, deficiencies, and toxicities.
This document provides an overview of an internship presentation at Hindustan Zinc Smelter Ltd. in Debari, Udaipur. It introduces the company and describes the key processes involved in zinc production including acid and roaster plants, leaching and purification, electrolysis, and melting and casting. It also summarizes the intern's project studying the operation and maintenance of the acid-roaster plant, outlining the basic processes within the plant such as roasting, gas cleaning, and sulfuric acid production.
Zinc is a trace mineral that is important for many functions in the body. The total body content of zinc is about 2 grams, with high concentrations found in the prostate gland, muscle tissue, and bone. Good dietary sources of zinc include meat, dairy products, legumes, nuts, and spinach. Zinc is required for the function of many enzymes and is involved in processes like DNA synthesis, wound healing, growth, and taste sensation. Zinc deficiency can result in issues like hypogonadism, growth failure, and skin lesions. Toxicity from excess zinc intake is rare but can cause nausea and gastrointestinal issues.
Este documento presenta información sobre las aleaciones de zinc, incluyendo sus propiedades, usos comunes y efectos de los elementos de aleación. Discute las aleaciones de zinc-aluminio usadas para moldeo y las aleaciones de zinc-plomo, zinc-cobre y zinc-magnesio usadas para forja. También cubre las ventajas y desventajas de las aleaciones de zinc, así como sus aplicaciones y limitaciones.
Metabolism of zinc and its clinical significancerohini sane
A comprehensive presentation on Metabolism of Zinc and its clinical significance for MBBS,BDS,B.Tech,B.Pharma and Biotechnology students for self-study.
Mineral metabolism (iodine & zinc) -Biochemistryautumnpianist
1) The document discusses mineral metabolism, focusing on iodine and zinc. Iodine is important for thyroid hormone production and zinc serves as a cofactor for many enzymes.
2) Iodine is obtained from foods like seafood, fish, and iodized salt. The thyroid gland concentrates iodine and uses it to produce the hormones thyroxine and triiodothyronine. Iodine deficiency can cause goiter and hypothyroidism.
3) Zinc is found in foods like legumes, potatoes, and cabbage. It is a cofactor for over 300 enzymes and is important for processes like wound healing. Zinc deficiency can impair growth and immune function.
The document discusses the evidence for using zinc supplementation in the treatment of childhood diarrhea. Zinc supplementation is now recommended as part of the global diarrhea treatment strategy based on multiple clinical trials showing it reduces diarrhea duration and severity. Zinc addresses diarrhea by maintaining gut integrity and functioning of the immune system. Proper dosage and duration of zinc treatment is important to gain its protective benefits against future diarrhea episodes. Ensuring widespread access to affordable zinc formulations is now a priority in developing countries.
Zinc is one of the strategic non-ferrous metal next only to Aluminium and Copper. It plays a very important role in country’s economy and development. It finds use in applications like galvanizing of iron and steel; die-casting alloys, brasses, dry cells, agriculture, chemicals, pharmaceuticals etc., with industrial development in India use of zinc has increased considerably, however, specific consumption is much lower as compared to other developing countries.
The most important raw material for the production of zinc is the sulphide ore from which zinc is extracted either through pyro-metallurgical route or through hydro metallurgical – Roast – Leach – Electrowin (RLE) route. At present nearly 80 - 85% of the world’s production of primary zinc is through hydrometallurgical route, the balance is through pyro – metallurgical route.
Zinc’s largest use is in corrosion protection. Galvanising is the main method of protection against corrosion of steel, i.e. the steel is coated with a layer of zinc in order to protect it from decay.
Brasses are alloys of copper and zinc, and they have good mechanical properties and good corrosion resistance.
Diecastings are precision castings that can be mass-produced. Rolled zinc is used for architectural and building applications, and for dry cell batteries. Zinc oxide has its main use in tyres and rubber products. Many other zinc chemicals are used in a wide range of applications.
This document discusses vitamin and mineral deficiencies. It describes the fat-soluble and water-soluble vitamins, how deficiencies can be primary or secondary, and provides details on specific vitamin deficiencies like vitamins A, D, and C. Vitamin A deficiency can cause night blindness and xerophthalmia. Vitamin D deficiency results in rickets in children and osteomalacia in adults. Scurvy is caused by vitamin C deficiency and is characterized by bone disease and hemorrhages.
Hindustan Zinc Limited operates zinc, lead and silver mines and smelting facilities in India. It produces zinc, lead, silver and sulfuric acid. The document discusses Hindustan Zinc's hydrometallurgical plant processes which involve roasting zinc sulfide ore to produce zinc oxide, leaching the zinc oxide in sulfuric acid to produce zinc sulfate, and electrolysis in a cell house to electrowin zinc from the zinc sulfate solution. It also summarizes three student projects on pneumatic conveying of zinc dust, installation of rotary control valves for material handling, and development of air conditioning for a crane cabin.
This document provides a summary report of a 15-day summer training program at a Hindustan Zinc Limited Captive Power Plant. It discusses the key components and processes involved in generating electricity from coal at a thermal power plant, including the boiler, turbine, condenser, and feed pump. The report also provides overviews of the coal handling process, basic instrumentation systems, programmable logic controllers, and concludes with references.
The document summarizes the key stages of hydrometallurgical processes. It discusses three main stages: leaching, solution concentration and purification, and metal recovery. Leaching involves dissolving metals from ores using techniques like heap, vat, or agitation leaching. Solution concentration and purification removes impurities. Metal recovery precipitates metals from the solution chemically or electrochemically, such as via electrowinning. Hydrometallurgy is more environmentally friendly than pyrometallurgy and can process lower grade ores, but requires more time and has challenges with separation and impurities.
Zinc plays an important role in immunity and diarrhea. Zinc deficiency is common in acute and chronic diarrhea and leads to impaired immune function. Studies show that zinc supplementation in children with diarrhea reduces duration and severity of diarrhea episodes. It does so by accelerating regeneration of the intestinal mucosa and enhancing cellular immunity. As zinc deficiency is prevalent in developing countries, zinc supplements can be useful as both a preventive and therapeutic intervention for diarrhea.
Trace minerals are needed in small amounts but are essential for many bodily functions. They include iron, zinc, iodine, selenium, fluoride, manganese, molybdenum, chromium, and others. Trace mineral deficiencies can impair growth, development, immunity and cognitive function, while toxicities of some like iron, fluoride, and iodine can also negatively impact health. Food content of trace minerals depends on soil mineral content where the food was grown.
“Pharmacology of Aminoglycosides: A Detailed Review for Medical and Pharmacy ...Dr. NIDHI SRIVASTAVA
Aminoglycosides are a powerful class of antibiotics known for their rapid bactericidal action against serious Gram-negative infections. This presentation offers a comprehensive yet engaging exploration of their pharmacology, tailored specifically for medical, dental, and pharmacy students preparing for exams or looking to strengthen their clinical foundation.
We begin with the fascinating history of aminoglycosides, from the discovery of streptomycin in the 1940s to the development of newer agents like amikacin and netilmicin. These drugs are natural or semi-synthetic derivatives of Streptomyces and Micromonospora species and have saved countless lives, especially in critical care settings.
You’ll then dive into their mechanism of action, where aminoglycosides irreversibly bind to the 30S ribosomal subunit, causing mRNA misreading and inhibition of bacterial protein synthesis. Unlike most protein synthesis inhibitors, aminoglycosides are bactericidal—a unique trait that makes them especially valuable in treating life-threatening infections.
Their entry into bacterial cells depends on oxygen and energy, which explains why they are ineffective against anaerobes and are often used in combination with beta-lactam antibiotics. This synergy enhances bacterial cell wall permeability, increasing aminoglycoside uptake and efficacy.
The presentation clearly outlines the spectrum of activity—highlighting their strong effectiveness against aerobic Gram-negative bacilli like E. coli, Pseudomonas, and Klebsiella. For certain Gram-positive infections (e.g., Enterococcus, Staphylococcus), aminoglycosides serve as part of combination therapy.
Each major aminoglycoside—gentamicin, tobramycin, amikacin, streptomycin, and kanamycin—is covered in terms of pharmacokinetics, dosing, and clinical use. We also discuss newer uses, such as inhaled tobramycin in cystic fibrosis and amikacin against multi-drug-resistant tuberculosis.
Safety is a key part of this review. Students will understand the mechanisms behind nephrotoxicity, ototoxicity, and neuromuscular blockade, with tips on how to monitor and minimize these risks in clinical practice. Therapeutic drug monitoring (TDM) and once-daily dosing strategies are also explained, reflecting current guidelines.
We also explore mechanisms of resistance—from modifying enzymes to ribosomal mutations and decreased permeability—and what this means for treatment choices in the age of antimicrobial resistance.
This presentation aims to balance core pharmacological concepts with clinical relevance. Whether you’re preparing for exams, giving a seminar, or revising for practicals, this visually rich and well-organized resource will enhance your understanding of aminoglycosides and their role in modern medicine.
In biomechanics, "load on the human body" refers to the forces and moments (torques) that act on the body during movement or while maintaining posture. Understanding these loads is crucial in fields like ergonomics, physical therapy, sports science, and injury prevention.
DR ALIYA S.M
Understanding Typhoid and How to Prevent It in Everyday LifeRaj Kumble
Explore a detailed overview of typhoid fever, including how it spreads, common symptoms, diagnosis, prevention strategies, and the importance of hygiene and vaccination. This presentation is ideal for health education sessions, schools, and public awareness programs aiming to promote safe practices and reduce infection risks.
This PDF contains a detailed nursing care plan for a patient with an ineffective breathing pattern. It includes assessment, nursing diagnosis, inference, goals, nursing interventions with rationale, implementation, and evaluation. Ideal for B.Sc. Nursing students and clinical practice reference.
The biomechanics of bone refers to how bone tissue responds to mechanical forces, including its structure, strength, and mechanical behavior under different loading conditions. Bone plays a vital role in supporting the body, protecting organs, and facilitating movement by transmitting muscular forces.
Dr Aliya Shair Muhammad
BUMHS, Quetta
A client-centered framework in ergonomics places the individual's needs, preferences, and context at the core of assessment and intervention. It emphasizes collaborative problem-solving between the therapist and client to design ergonomic solutions that are functional, meaningful, and sustainable in the client’s daily life or work environment.
AI in Esophageal Radiotherapy Planning: Not Ready for Clinical Use
The potential for Artificial Intelligence (AI) to enhance radiotherapy (RT) planning in esophageal cancer is a topic of growing interest. AI could revolutionize the field by improving treatment precision, reducing clinician workload, and increasing overall treatment efficiency. However, despite these promising possibilities, AI is not yet ready for clinical use in esophageal cancer radiotherapy planning, due to several significant challenges.
Esophageal cancer is challenging for radiation therapy due to its complex anatomy, where the esophagus is closely situated near vital structures like the lungs, heart, and spinal cord. This makes treatment planning labor-intensive, as it requires precise dose distribution to avoid damage to critical organs while effectively targeting the tumor. Currently, clinicians rely on advanced techniques such as contouring, image registration, and dose optimization, which are difficult to automate, especially in esophageal cancer.
While AI has made advancements in areas like tumor detection, segmentation, and plan evaluation, its application in esophageal RT planning faces limitations. One of the main barriers is the scarcity of large, diverse datasets to train AI models. Esophageal cancer has considerable patient variability, with differences in tumor size, location, and anatomical structures. AI models trained on insufficient or homogeneous datasets risk producing unreliable results when applied to diverse clinical settings.
Another significant limitation is that AI systems are not yet capable of making the complex clinical decisions that human oncologists do. For example, AI may assist in tumor segmentation but lacks the ability to fully understand the nuances of tumor behavior, patient comorbidities, or changes in anatomy throughout the treatment course. Tumors can shrink or shift during therapy, making the positioning of surrounding organs dynamic. AI models often struggle to adapt to these changes in real-time, requiring continual human oversight.
Additionally, AI’s "black-box" nature presents a challenge. AI algorithms are often not transparent, meaning clinicians may not fully understand why certain decisions are made. In the highly sensitive field of radiation oncology, where small errors can have serious consequences, the inability to explain AI's decision-making process is a critical issue. Clinicians need to trust and validate the AI-generated treatment plans to ensure patient safety and optimal outcomes.
Regulatory and ethical challenges also hinder AI adoption in clinical settings. AI applications must undergo rigorous validation and approval from bodies such as the FDA, and in the case of esophageal RT, the evidence supporting AI's reliability, safety, and clinical benefit is still insufficient. Moreover, ethical considerations like data privacy, algorithmic bias, and patient consent need to be addressed before AI can be widely .
Presentation on steroids medical uses and potential side effectso9m26a11r4
a presentation about steroids
as you all know steroids is a broad topic and in this presentation we covered some of the topics
We discussed the medical uses and the harmful side effects ofcourse after cooking the basic structure.
This presentation originally is an assessment in Scientific SKILLS and Communication course
Building a healthier society for for the future - annual launch of the ILC's ...ILCUK
Two years ago we launched the Healthy Ageing and Prevention Index.
The Index is an online interactive tool that ranks 153 countries on six healthy ageing metrics to understand how well countries have adapted to longevity.
In our Index we look at health, wealth and societal metrics, including life span, health span, work span, income, environmental performance and happiness
We now have data for years 2019 and 2022 which allows us to track progress over time.
These are the top 50 countries on our Index in 2022.
Iceland replaced Switzerland as the top ranked country in 2022.
In the top 20 ranked countries the average movement up or down the Index between 2019 and 2022 was 2.1 places compared with 4.9 places in the bottom 20 ranked countries. On average, countries moved 4.6 places.
More than a third of the top 20 countries are members of the EU.
Between 2019 and 2022 we have become unhealthier, more unequal and less environmentally sustainable
Inequalities in life span and health span have also widened since 2019, with the gap between the top 10 and bottom 10 countries on our Index increasing by 1 more year (with the gap in life span now 27 years and the gap in health span now 24 years).
While happiness levels have remained relatively unchanged and we work the same number of years and we’re also richer, income inequalities have widened by 6.5% between the top and bottom 25% of countries.
In fact, this widening of inequalities is due to the top 25% of countries seeing an increase in per capita income, while the bottom 25% seeing a decrease in per capita income.
Countries with a higher vaccine rate not only have a greater life span but they also perform better on the Index.
The top 5 countries (Mexico, UK, South Korea, Denmark and Portugal) have an average flu vaccination rate of 82%, an average life span of 81 years and an average ranking of 25 on our Index
The bottom 5 countries (Latvia, Turkey, Bulgaria, Poland and Slovakia) have an average flu vaccination rate of 10%, an average life span of 76 years and an average ranking of 51 on our Index.
Carotid doppler ultrasound indication, method , application and most common pitfalls. We have covered everything you must know about carotid ultrasound.
Type 2 Diabetes Mellitus: Overview, Management, and PreventionMAHESH MARRI
Presentation Description:
Title: Type 2 Diabetes Mellitus: A Comprehensive Overview from Pathophysiology to Management
Audience: Healthcare professionals, medical students, researchers, and public health educators.
Objective:
This presentation provides an in-depth analysis of Type 2 Diabetes Mellitus (T2DM), covering its epidemiology, pathophysiology, clinical presentation, diagnostic criteria, complications, and evidence-based management strategies. The goal is to enhance understanding of T2DM as a global health challenge and highlight preventative and therapeutic approaches to improve patient outcomes.
Key Topics Covered:
1. Epidemiology & Risk Factors – Global prevalence, high-risk populations, and modifiable vs. non-modifiable risks.
2. Pathophysiology – Insulin resistance, beta-cell dysfunction, and the role of hyperglycemia.
3. Diagnosis – ADA criteria (HbA1c, FPG, OGTT) and early detection strategies.
4. Complications – Acute (HHS, hypoglycemia) and chronic (retinopathy, nephropathy, CVD).
5. Management –
o Lifestyle interventions (diet, exercise, weight loss).
o Pharmacotherapy (Metformin, SGLT2 inhibitors, GLP-1 agonists, insulin).
6. Emerging Therapies – Advances in stem cell research, artificial pancreas systems, and dual agonist drugs.
7. Prevention & Patient Education – Screening guidelines and self-care practices.
Why This Presentation Matters:
T2DM is a leading cause of morbidity and mortality worldwide, but early intervention can prevent complications. This PPT equips audiences with practical knowledge to tackle T2DM in clinical and public health settings.
Chair, Tanya Gupta, MD, discusses breast cancer in this CME/MOC/NCPD/AAPA activity titled “Navigating the Clinical Integration of TROP2-Targeted ADCs in TNBC and HR+, HER2- Metastatic Breast Cancer: A Customized Learning Journey.” For the full presentation, downloadable Practice Aids, and complete CME/MOC/NCPD/AAPA information, and to apply for credit, please visit us at https://bit.ly/3ChEsv4. CME/MOC/NCPD/AAPA credit will be available until May 13, 2026.
1. Location
* Largest of the salivary glands.
* Located in the **parotid region**, anterior and inferior to the external ear.
* Lies **superficial to the masseter muscle** and wraps around the **posterior border of the ramus of the mandible**.
2. Shape and Parts**
* Irregularly wedge-shaped.
* Has **superficial and deep lobes**, separated by the **facial nerve**.
3. Coverings**
* Enclosed in a tough **parotid fascia** (capsule) derived from the **deep cervical fascia
4. Relations
Anterior:** Masseter muscle, mandible.
Posterior:** Sternocleidomastoid, mastoid process, posterior belly of digastric.
Medial:** Styloid process and associated muscles (stylopharyngeus, styloglossus, stylohyoid).
Superior:** Zygomatic arch.
Inferior:** Angle of the mandible.
5. Structures within the Parotid Gland (Superficial to Deep)**
Facial nerve (CN VII)**
Retromandibular vein**
External carotid artery**
6. Duct**
Stensen’s duct (Parotid duct)**:
Emerges from the anterior border.Crosses the **masseter muscle**, pierces the **buccinator**, and opens **opposite the upper 2nd molar** in the oral cavity.
7. Blood Supply**
Arterial:** External carotid artery (posterior auricular, superficial temporal, maxillary branches).
* **Venous:** Retromandibular vein.
8. Lymphatic Drainage**
Superficial and deep parotid nodes** → **deep cervical nodes**.
9. Nerve Supply**
Sensory:** Auriculotemporal nerve (branch of mandibular nerve – CN V3).
Parasympathetic (secretomotor):** Glossopharyngeal nerve (CN IX) → via **otic ganglion** → **auriculotemporal nerve**.
* **Sympathetic:** From **plexus on external carotid artery** (vasomotor).
10. Clinical Relevance**
Facial nerve palsy** risk during surgery.
* Common site for **pleomorphic adenoma**.
* **Mumps**: viral infection causing painful swelling of the parotid.
* **Frey's syndrome**: gustatory sweating due to auriculotemporal nerve injury.
2. What is Zinc
Zinc is a mineral that is in some foods such as oysters
and beef.
Zinc is a silvery metal that is a constituent (a whole)
brass.
It is used coating iron and steel to protect from
corrosion.
Fig. 1 Fig. 2
4. Why do we need it
Zinc plays a vital role in bringing the vitamin A from the
liver to the retina.
It helps Build and Repair our Cells and Tissues.
Zinc helps us Digest our food.
Zinc helps us maintain strong and healthy bones.
Fig. 6
5. Deficiency of Zinc
Zinc is an essential mineral to a few of your major body
systems.
Deficiency of zinc can lead to delayed growth and
impaired ability to fight infections.
Deficiency of zinc can also decrease your ability to
absorb nutrients.
Fig. 7
6. Fun Fact
Zinc has been used for over 2,500 years!
Over 50 countries produce zinc, the largest being
China!
Zinc can help you stay young!
Fig. 8