This document provides guidance on lumbar drains including: - Lumbar drain placement is a sterile procedure typically between the L3-L4 or L4-L5 vertebrae. - Indications for lumbar drains include CSF analysis, treatment of hydrocephalus, and delivery of medications. - Monitoring of lumbar drains involves frequent neuro checks and documentation of CSF color, clarity and volume drained. - Lumbar drain trials may be used to diagnose normal pressure hydrocephalus and involve draining 8-10mL of CSF every hour.