The mission of the Flatiron Institute is to advance scientific research through computational methods, including data analysis, theory, modeling and simulation.

Simons Foundation

Featured News

Center for Computational Mathematics CCM Group Leader Marsha Berger Named 2025 John von Neumann Prize Lecturer by Society of Industrial and Applied Mathematics By Jane Beaufore

Center for Computational Mathematics CCM Scientist Jiequn Han Receives Early Career Prize from Society of Industrial and Applied Mathematics

Center for Computational Astrophysics Hyped Signal of Decaying Dark Matter Vanishes in Updated Analysis

Our Centers

Center for Computational Astrophysics

Center for Computational Biology

Center for Computational Mathematics

Center for Computational Neuroscience

Center for Computational Quantum Physics

Scientific Computing Core

It develops, deploys and maintains computational infrastructure — from supercomputers to desktop PCs — dedicated solely to the use of Flatiron researchers.

Initiatives

Initiative for Computational Catalysis

The Simons Foundation Initiative for Computational Catalysis is a new effort within the Flatiron Institute dedicated to the development and application of computational techniques enabling the rational design of more efficient and more affordable catalysts.

Collaborative Work

Machine Learning at the Flatiron Institute

Machine learning has become an indispensable tool for computational science, and it is an active and growing area of research throughout the Flatiron Institute.

Structural and Molecular Biophysics

Underlying all biological processes are molecules and their interactions with each other. However, our ability to understand how these molecules function over biologically relevant scales remains very limited.

Learning the Universe

This collaboration, directed by Greg Bryan of Columbia University, aims to understand and determine the evolution and initial conditions of our universe, using observations via a Bayesian forward modeling approach.

CCA
| Columbia University
| Lawrence Berkeley National Lab
| Harvard University
| Stockholm University
| Institute D'Astrophysique de Paris
| Université de Montreal
| Princeton University
| Carnegie Mellon University
| Max-Planck Institute for Astrophysics

Flatiron Institute Inclusion, Diversity,
Equity & Advocacy (IDEA) Scholar Program

For distinguished scientists with a particular interest in diversity and inclusion

Scholars may engage in a variety of activities, such as working on scientific projects, starting new collaborations, mentoring junior scientists, and organizing or participating in workshops and career development events.

Learn More

A major effort of the Flatiron Institute is the development and support of high-quality, open-source software for research.

View All Software

Research Highlights

January 9, 2025

Disentangling Interacting Systems with Fermionic Gaussian Circuits: Application to the Single Impurity Anderson Model

Ang-Kun Wu, B. Kloss, Wladislaw Krinitsin, M. Fishman, J. Pixley, M. Stoudenmire

Tensor network quantum states are powerful tools for strongly correlated systems, tailored to capture local correlations such as in ground…

Physical Review B

January 3, 2025

Geometric model for dynamics of motor-driven centrosomal asters

Yuan-Nan Young, Vicente Gomez Herrera, Huan Zhang, R. Farhadifar, M. Shelley

The centrosomal aster is a mobile and adaptable cellular organelle that exerts and transmits forces necessary for tasks such as…

Physical Review Research

January 1, 2025

The 2024 New York City Integrative Structural Biology Symposium

P. Cossio, Edward T. Eng

The 2024 New York City Integrative Structural Biology Symposium focused on understanding the challenges and opportunities of applying integrative structural…

Trends in Pharmacological Sciences

News & Announcements

Center for Computational Neuroscience

February 25, 2025

CCN’s NeuroRSE Group Hosts Two Software Workshops By Jane Beaufore

Participants pose for a photo at the February 2025 workshop.

Center for Computational Mathematics

February 24, 2025

CCM Scientist Jiequn Han Receives Early Career Prize from Society of Industrial and Applied Mathematics By Jane Beaufore

Center for Computational Mathematics

February 13, 2025

CCM Group Leader Marsha Berger Named 2025 John von Neumann Prize Lecturer by Society of Industrial and Applied Mathematics By Jane Beaufore

Leadership

Leslie Greengard, M.D., Ph.D.

Director, CCM

Leslie Greengard joined the Simons Foundation in 2013 as founding director of the Simons Center for Data Analysis, now called the Center for Computational Biology. Prior to that, Greengard served as director of the Courant Institute of Mathematical Sciences at New York University.

Julianne Dalcanton, Ph.D.

Director, CCA

Julianne Dalcanton joined the Simons Foundation in September 2021 as the director of the Flatiron Institute’s Center for Computational Astrophysics (CCA). Her research specializes in the origins and evolution of galaxies.

Ian Fisk, Ph.D.

Director, SCC

Ian Fisk came to the Simons Foundation in 2014 after working in the computing division at the Fermi National Accelerator Laboratory in Illinois since 2003. Fisk was the Compact Muon Solenoid (CMS) experiment’s computing coordinator at CERN from 2010 to 2013, overseeing operations and improvements…

Antoine Georges, Ph.D.

Director, CCQ

Antoine Georges is a professor of physics at the Collège de France, where he holds the chair in condensed matter physics. He also has joint appointments with École Polytechnique and the University of Geneva. He received his Ph.D. from the École Normale Supérieure in 1988.…

Andrew Millis, Ph.D.

Collaboration Director

Andrew Millis is co-director of the Center for Computational Quantum Physics at the Flatiron Institute and professor of physics at Columbia University. He currently serves as Managing Director of the Flatiron Institute.

Michael Shelley, Ph.D.

Director, CCB

Michael Shelley joined the Simons Foundation in 2016 to work on the modeling and simulation of complex systems arising in physics and biology.

Eero P. Simoncelli, Ph.D.

Director, CCN

Eero P. Simoncelli is the inaugural director of the Center for Computational Neuroscience. Eero P. Simoncelli’s research interests span a wide range of topics in the representation and analysis of visual images and sounds in both machine and biological vision systems.