₹0
INTRODUCTION ABOUT OXRA 10MG TABLET
OXRA 10MG TABLET is used to manage type II diabetes mellitus when diet and exercise does not result in adequate control on blood glucose levels. It is also used in the management of heart failure and chronic kidney disease (reduced kidney function). It contains Dapagliflozin which belongs to the group of medicines called Antidiabetic agents.
During therapy with OXRA 10MG TABLET, your doctor might regularly monitor blood sugar levels and kidney functions to avoid the risk of unwanted side effects. Before taking the medicine, inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have type I diabetes, severe low blood pressure, severe dehydration or conditions which can cause dehydration (such as nausea, vomiting, fever, serious illness or any surgery).
The most common side effects are back pain, passing more urine, constipation, dizziness and rash. Consult your physician if any of these side effect worsens.
USES OF OXRA 10MG TABLET
It is used to manage:
HOW OXRA 10MG TABLET WORKS
OXRA 10MG TABLET contains Dapagliflozin which works by blocking the action of a protein called SGLT-2 in the kidneys. This action manages the reabsorption of glucose and sodium ions in the kidneys. As a result, it excretes excess glucose and from the body in the form urine leading to decrease in blood sugar levels. It also protects kidney function and manages it from further damage. Additionally, it reduces the strain on the heart and helps it to pump blood more efficiently with less pressure.
DIRECTIONS FOR USE
- Take OXRA 10MG TABLET as advised by your physician
- Swallow the medicine with a glass of water. Do not crush or chew the medicine. It can be taken with or without meals
- Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition
- Do not stop taking OXRA 10MG TABLET unless your doctor advice you to stop
SIDE EFFECTS OF OXRA 10MG TABLET
Common side effects of OXRA 10MG TABLET:
- fungal infections of genital (thrush) causing itching, irritation, unusual discharge, odor
- back pain
- passing more urine, increased urine frequency
- dizziness
- skin rash
- dehydration, thirst
- constipation
- dry mouth
Stop taking OXRA 10MG TABLET and contact your doctor immediately if you experience any of the following side effects such as:
- signs of allergic reaction (skin rash, itching, swelling of the face, tongue or throat, causing difficulty in breathing and swallowing)
- signs of diabetic ketoacidosis (nausea or vomiting, stomach pain, excessive thirst, fast and deep breathing, confusion, unusual sleepiness or tiredness, a sweet smell to breath, a sweet or metallic taste in the mouth or a different odor to urine or sweat, and rapid weight loss)
- pain, swelling, redness or tenderness of the genitals or the areas between the genitals and the anus accompanied with high fever or a feeling generally unwell (sign of necrotizing fasciitis of the perineum)
- signs of urinary tract infection (such as fever and/or chills, burning sensation while passing urine, pain in the back or side)
- bloody urine
- signs of low blood sugar levels (shaking, sweating, anxiety, hunger, fast heartbeat, headache, change in vision, mood swings, confusion)
WARNING & PRECAUTIONS
PREGNANCY
Consult your doctorThere are limited for the use of OXRA 10MG TABLET in pregnant women Therefore, the use of this medicine is not recommended during the second and third trimesters of pregnancy.
BREASTFEEDING
Consult your doctorIt is unknown whether OXRA 10MG TABLET and/or its metabolites are excreted in human milk. Consult your doctor before taking the medicine.
DRIVING AND USING MACHINES
Use with CautionOXRA 10MG TABLET does not affect your ability to drive or operate any heavy tools or machines. However, if it is combined with other antidiabetic medicines, it may cause dizziness, shakiness, or vision changes. Therefore, do not drive or handle any heavy tools if your ability is affected by the medicine.
ALCOHOL
Consult your doctorAvoid consumption of alcohol while taking OXRA 10MG TABLET as it may increase the risk of unwanted side effects.
KIDNEY
Use with CautionOXRA 10MG TABLET should be used with caution in patients with kidney problems.
LIVER
Use with CautionOXRA 10MG TABLET should be used with caution in patients with liver problems.
ALLERGY
ContraindicatedDo not take OXRA 10MG TABLET if you are allergic to Dapagliflozin or any other ingredients of this medicine.
USE IN PEDIATRICS
Consult your doctorThere is no data available in children below 10 years of age. Consult your doctor for advice.
USE IN GERIATRICS
Use with CautionOXRA 10MG TABLET should be used with caution in elderly patients (aged 65 years or above).
OTHERS
Before taking OXRA 10MG TABLET, inform your doctor if you:
- have type I diabetes (insulin-dependent diabetes)
- have diabetes related kidney problem
- have low blood pressure
- have uncontrollably high levels of blood glucose levels
- have fever, nausea, vomiting or if you are unable to eat or drink anything
- often get infections of the urinary tract
- are on fasting
- are dehydrated (due to recent vomiting, diarrhea or other reasons)
- have any serious illness or had a major surgery recently
INTERACTIONS
A. Drug-Drug interactions:
Before taking the medicine, inform your doctor if you are taking any of the following medicines such as:
- diuretics (Ex. furosemide, hydrochlorothiazide)
- Antidiabetics (Ex. insulin or glimepiride, gliclazide)
Overdosage:
If you or anyone else accidentally take too much of OXRA 10MG TABLET, consult your doctor immediately or visit the nearby hospital.
SYNOPSIS
| Drug | : | Dapagliflozin |
| Pharmacological Category | : | SGLT-2 Inhibitors |
| Therapeutic Indication | : | Type II Diabetes Mellitus, Heart Failure, Chronic Kidney Disease |
| Dosage Forms | : | Tablet |
FAQs ABOUT OXRA 10MG TABLET
Q: What is OXRA 10MG TABLET used for?
A: OXRA 10MG TABLET is used to manage type II diabetes mellitus in adults and in children (aged 10 years or older) when diet and exercise does not result in adequate control on blood glucose levels. It can also be used to manage heart failure and chronic kidney disease (reduced kidney function) in adults.
Q: Is OXRA 10MG TABLET safe to use in children?
A: There are limited for the use of OXRA 10MG TABLET in pregnant women Therefore, the use of this medicine is not recommended during the second and third trimesters of pregnancy.
Q: Can the use of OXRA 10MG TABLET cause weight loss?
A: OXRA 10MG TABLET may cause weight loss in some individuals. It is because of excessive loss of fluid from the body in the form of urine. However, consult your doctor if this side effect troubles you.
Q: Can OXRA 10MG TABLET affects pregnancy?
A: There are limited for the use of OXRA 10MG TABLET in pregnant women Therefore, the use of this medicine is not recommended during the second and third trimesters of pregnancy.
Q: Can OXRA 10MG TABLET cause urinary tract infection?
A: Yes, taking OXRA 10MG TABLET may cause urinary tract infections in few peoples. Not every individual gets the side effect, so it is always better to practice good hygiene. Contact your doctor for advice.
Q: How does OXRA 10MG TABLET work?
A: OXRA 10MG TABLET is a SGLT-2 inhibitor. It works by blocking the action of a protein called SGLT-2 in the kidneys. This action manages the reabsorption of glucose and sodium ions in the kidneys. As a result, it excretes excess glucose and from the body in the form urine leading to decrease in blood sugar levels. It also protects kidney function and manages it from further damage. Additionally, it reduces the strain on the heart and helps it to pump blood more efficiently with less pressure.
Q: How and when to take OXRA 10MG TABLET?
A: Take OXRA 10MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. It can be taken with or without meals.
Q: How long should I take OXRA 10MG TABLET?
A: You need to take OXRA 10MG TABLET as long as your doctor prescribes you the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Q: What to do if I forgot to take a dose of OXRA 10MG TABLET?
A: If you forgot to take a dose of OXRA 10MG TABLET, take it as soon as you remember. However, if it is time for the next dose of OXRA 10MG TABLET, skip the missed dose and take the next one regularly.
Q: What are the most common side effects of taking OXRA 10MG TABLET?
A: The most common side effects of taking OXRA 10MG TABLET are genital infections, back pain, passing more urine, constipation, dizziness and rash. Contact your physician if any of these side effect worsens.
Q: Will taking a higher dose of OXRA 10MG TABLET be more effective?
A: No, taking a higher dose of OXRA 10MG TABLET will not be effective rather it can lead to toxicity. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.
Q: What precautions do I need to follow while taking OXRA 10MG TABLET?
A: Before taking OXRA 10MG TABLET inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have severe low blood pressure or are severely dehydrated due to excessive vomiting or diarrhea. Along with the therapy, follow the diet and lifestyle changes advised by your doctor to achieve better results.
Q: Can I take OXRA 10MG TABLET with metformin?
A: Studies have shown that the combination of OXRA 10MG TABLET with metformin may effectively control blood sugar levels. However, the combination should be used only under careful medical supervision.
Q: Can OXRA 10MG TABLET be taken with insulin?
A: Co-administration of OXRA 10MG TABLET with insulin is considered risky as they increase the chance of hypoglycemia (decreased blood sugar levels). Therefore, consult your doctor before taking it.
Q: Can OXRA 10MG TABLET cause constipation?
A: Yes. Constipation is a common side effect of taking OXRA 10MG TABLET. Eat plenty of fiber rich foods such as fresh fruits, vegetables, cereals as well as drink plenty of water and exercise more regularly while taking this medicine. Contact your doctor if this side effect bothers you.
REFERENCES
1. KD. Tripathi. Insulin, oral hypoglycaemic drugs, and glucagon. Essentials of medical pharmacology. Seventh edition. 2013. Page – 278.
2. Sarah L. Anderson. Dapagliflozin efficacy and safety: a perspective review. National Institute of Health. NLM. National Centre for Biotechnology Information. PMC. Pubmed Central. December 2014. [Accessed on 31st October 2022] click here
3. John J.V. McMurray, Scott D. Solomon, Silvio E. Inzucchi, Lars Kober, Mikhail N. Kosiborod, Felipe A. Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction. The New England Journal of Medicine. November 2019. [Accessed on 31st October 2022] click here
4. Feng, Miao MM, Lv, Haihong PhD, Xu, Xia MM, Wang, Jue MM, Lyu, Wenyi MA, Fu, Songbo MM, Li., Sheyu. Efficacy and safety of dapagliflozin as monotherapy in patients with type 2 diabetes mellitus. Journal of Medicines. July 2019. [Accessed on 31st October 2022] click here
5. AstraZeneca UK Limited. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on 9th June 2022] click here
AUTHOR DETAILS
ALTERNATE BRANDS View All
₹0
₹0
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.