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Measuring storage and loss moduli using optical tweezers: broadband microrheology

Phys Rev E Stat Nonlin Soft Matter Phys. 2010 Feb;81(2 Pt 2):026308. doi: 10.1103/PhysRevE.81.026308. Epub 2010 Feb 18.

Abstract

We present an experimental procedure to perform broadband microrheological measurements with optical tweezers. A generalized Langevin equation is adopted to relate the time-dependent trajectory of a particle in an imposed flow to the frequency-dependent moduli of the complex fluid. This procedure allows us to measure the material linear viscoelastic properties across the widest frequency range achievable with optical tweezers.

Publication types

  • Research Support, Non-U.S. Gov't