Pentasa 1 gm 14 Suppositories

Product Description:

PENTASA suppositories contain mesalazine, which has an anti-inflammatory effect, and is used in the treatment of:

• Active ulcerative proctitis , an inflammatory condition with ulceration in the rectum .

How To Use:

• Always use this medicine exactly as your doctor or pharmacist has told you. 
• Contact a doctor or pharmacist if you are unsure.

Adults:

• Usual dose is one suppository once daily.
• The suppository is inserted into the rectum.

Children:

• There is little experience and only limited documentation with regard to effectiveness.
• If you think that the effect of PENTASA suppositories is too strong or too weak, you should consult your doctor or pharmacist about this.

Instructions for use:

• It is recommended that you go to the toilet before using the suppositories.
• Place one of the supplied finger guards on the insertion finger.
• If it is difficult to insert the suppository, it can be moistened with a little water just before insertion.
• Throw away the used finger guard.

If you take too much Pentasa:

• Contact a doctor, hospital or Poison Information.
• If you have taken too much medicine or if a child has taken medicine by accident. 
• For other questions about the medicine, contact your doctor or pharmacist.

If you have forgotten to take Pentasa:

• You should not take a double dose to make up for a missed dose.

If you stop treatment with Pentasa:

• Ask your doctor or pharmacist if you have any questions about the use of this medicine.

Warnings And Precautions:

Do not use Pentasa:

• If you are allergic to mesalazine or any of the other ingredients of this medicine.
• If you are allergic to salicylates,
• If you have severe liver or kidney disorders.

Talk to your doctor or pharmacist before using Pentasa:

• If you are allergic to sulfasalazine, as in such cases there may also be a certain risk of allergic reactions to PENTASA suppositories (risk of allergy to salicylates),
• If you have impaired liver or kidney function; further precautions are agreed with a doctor,
• If you are using certain other medicines at the same time (see next section),
• If you have lung diseases, especially asthma.
• If serious changes occur in the blood picture or inflammation of the heart muscle and pericardium (myocarditis and pericarditis).
• A doctor should be contacted and the treatment discontinued. 

Such conditions are seen in rare cases:

• Signs of serious changes in the blood picture can be bleeding, bruising, sore throat and fever . 
• Signs of inflammation of the heart muscle and pericardium are fever and chest pain followed by shortness of breath.
• If you have ever had a severe rash or peeling of the skin, blisters and/or mouth sores after using mesalazine. 
• In connection with treatment with mesalazine, serious skin reactions have been reported, including Stevens-Johnson syndrome and toxic epidermal necrolysis . 
• Stop taking mesalazine and consult a doctor immediately if you develop any of the symptoms associated with severe skin reactions.
• While you are being treated with this medicine, your doctor will usually carry out blood and urine tests to check your kidney function, especially at the start of treatment.
• Kidney stones can form when using mesalazine. 
• Symptoms can be pain in the sides of the stomach and blood in the urine . 
• Be sure to drink enough fluids during treatment with mesalazine.

Pregnancy And Breastfeeding:

• Talk to your doctor or pharmacist before taking this medicine if you are pregnant or breast-feeding, think you may be pregnant or plan to become pregnant.
• There is little experience with the use of PENTASA during pregnancy. 
• The active ingredient in PENTASA crosses the placenta, and it is possible that the fetus could be affected. Therefore, consult a doctor before using  PENTASA if you are pregnant.
• The active substance in PENTASA passes into breast milk, and it is possible that children who are breastfed may be affected. 
• If the child develops diarrhoea , breastfeeding should be stopped.

Driving and using machines:

• PENTASA suppositories have no or negligible influence on the ability to drive and use machines.

Ingredients:

• The active substance is 1 g of mesalazine.

What  PENTASA looks like and contents of the pack:

• The preparation is supplied in aluminum blister packs.
• Pack size: 28 suppositories