Developmental biology articles from across Nature Portfolio

Developmental biology is the field of biology that studies the processes by which multicellular organisms grow and develop, controlled by their genes. Knowledge of normal developmental processes can aid in the understanding of developmental abnormalities and other conditions such as cancer.

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Building a molecular reference map of the human embryo

Two independent studies provide comprehensive human embryo reference maps by integrating multiple human embryo single-cell RNA sequencing (scRNA-seq) datasets. These references are instrumental in advancing cell type annotation and benchmarking stem cells and stem cell–based embryo models.
- Rina C. Sakata
- Marta N. Shahbazi
News & Views14 Nov 2024 Nature Methods
P: 1-2
Growth area: early studies exploring how tissues and cells grow

A book discusses interesting insights from studies of growth, and a plea is made for researchers to become more involved in shaping government science policy in this week’s snippets from Nature’s past.

News & Views12 Nov 2024 Nature
Volume: 635, P: 294
Cardiac regeneration leads to altered Purkinje fiber network and ventricular conduction

In newborn mice, after a neonatal cardiac infarction, cells derived from the ventricular trabeculae participate in the repair of the contractile myocardium, but this process results in excessive production of immature Purkinje fibers that form a hyperplastic network and lead to altered ventricular conduction.

News & Views12 Nov 2024 Nature Cardiovascular Research
Volume: 3, P: 1272-1273

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Latest Research and Reviews

The influence of relative pubertal maturity on executive function development in adolescent girls
- Patrícia Gerván
- Gyöngyi Oláh
- Ilona Kovács
ResearchOpen Access15 Nov 2024 Scientific Reports
Volume: 14, P: 28140
Extracellular vesicles derived from endothelial progenitor cells modified by Houshiheisan promote angiogenesis and attenuate cerebral ischemic injury via miR-126/PIK3R2
- Yawen Zhang
- Qiuyue Yang
- Qiuxia Zhang
ResearchOpen Access15 Nov 2024 Scientific Reports
Volume: 14, P: 28166
Deep learning-based models for preimplantation mouse and human embryos based on single-cell RNA sequencing

This Resource uses deep learning-based tools to build a dynamic transcriptomic reference for mouse and human preimplantation development.
- Martin Proks
- Nazmus Salehin
- Joshua M. Brickman
ResearchOpen Access14 Nov 2024 Nature Methods
P: 1-10
dab2 is required for the scavenging function of lymphatic endothelial cells in the zebrafish meninges
- Katharina Uphoff
- Irina Suárez
- Stefan Schulte-Merker
ResearchOpen Access14 Nov 2024 Scientific Reports
Volume: 14, P: 27942
Open-ended molecular recording of sequential cellular events into DNA

Loveless, Carlson and colleagues describe peCHYRON, a DNA recorder that propagates an unending chain of insertions. Each link contains a randomizable 3-bp ‘signature’ sequence that serves to record a cellular event in the order it occurred.
- Theresa B. Loveless
- Courtney K. Carlson
- Chang C. Liu
Research14 Nov 2024 Nature Chemical Biology
P: 1-10
A comprehensive human embryo reference tool using single-cell RNA-sequencing data

This resource integrates different human embryo datasets to create a transcriptional reference map of human embryonic development from zygote to gastrula.
- Cheng Zhao
- Alvaro Plaza Reyes
- Fredrik Lanner
ResearchOpen Access14 Nov 2024 Nature Methods
P: 1-14

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News and Comment

Building a molecular reference map of the human embryo

Two independent studies provide comprehensive human embryo reference maps by integrating multiple human embryo single-cell RNA sequencing (scRNA-seq) datasets. These references are instrumental in advancing cell type annotation and benchmarking stem cells and stem cell–based embryo models.
- Rina C. Sakata
- Marta N. Shahbazi
News & Views14 Nov 2024 Nature Methods
P: 1-2
Bone marrow in the skull plays a surprisingly important role in ageing

Over the lifespan, skull bone marrow takes a more prominent role producing vital blood cells — plus how a radioactive lead isotope could help age the Solar System.
- Nick Petrić Howe
- Elizabeth Gibney
News13 Nov 2024 Nature
Growth area: early studies exploring how tissues and cells grow

A book discusses interesting insights from studies of growth, and a plea is made for researchers to become more involved in shaping government science policy in this week’s snippets from Nature’s past.

News & Views12 Nov 2024 Nature
Volume: 635, P: 294
Cardiac regeneration leads to altered Purkinje fiber network and ventricular conduction

In newborn mice, after a neonatal cardiac infarction, cells derived from the ventricular trabeculae participate in the repair of the contractile myocardium, but this process results in excessive production of immature Purkinje fibers that form a hyperplastic network and lead to altered ventricular conduction.

News & Views12 Nov 2024 Nature Cardiovascular Research
Volume: 3, P: 1272-1273
The −KTS isoform of Wt1 induces the transformation of Leydig cells into granulosa-like cells
- Changhuo Cen
- Bowen Liu
- Fei Gao
CorrespondenceOpen Access12 Nov 2024 Cell Discovery
Volume: 10, P: 113
8 million cells: virtual embryo shows organs forming in exquisite detail

Model used to create a cellular ‘hologram’ of a mouse embryo could be used to visualize development in any species.
- Smriti Mallapaty
News11 Nov 2024 Nature

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Developmental biology articles from across Nature Portfolio

Featured

Building a molecular reference map of the human embryo

Growth area: early studies exploring how tissues and cells grow

Cardiac regeneration leads to altered Purkinje fiber network and ventricular conduction

Related Subjects

Latest Research and Reviews

The influence of relative pubertal maturity on executive function development in adolescent girls

Extracellular vesicles derived from endothelial progenitor cells modified by Houshiheisan promote angiogenesis and attenuate cerebral ischemic injury via miR-126/PIK3R2

Deep learning-based models for preimplantation mouse and human embryos based on single-cell RNA sequencing

dab2 is required for the scavenging function of lymphatic endothelial cells in the zebrafish meninges

Open-ended molecular recording of sequential cellular events into DNA

A comprehensive human embryo reference tool using single-cell RNA-sequencing data

News and Comment

Building a molecular reference map of the human embryo

Bone marrow in the skull plays a surprisingly important role in ageing

Growth area: early studies exploring how tissues and cells grow

Cardiac regeneration leads to altered Purkinje fiber network and ventricular conduction

The −KTS isoform of Wt1 induces the transformation of Leydig cells into granulosa-like cells

8 million cells: virtual embryo shows organs forming in exquisite detail

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