Extended Data Figure 3: Concentration of ZIKV E-protein-specific IgG in mice.
From: Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination
a, b, Serum from C57BL/6 mice (a; n = 4 control; n = 8 ZIKV mRNA–LNP) or BALB/c mice (b; n = 5 control; n = 10 ZIKV mRNA–LNP) was analysed by ELISA, and estimates of the concentration of ZIKV E-protein-specific IgG were calculated using the mouse monoclonal antibody NR-4747 as a standard. Points represent individual mice; horizontal lines indicate the mean. Responses in vaccine and control groups were compared at each time point by Mann–Whitney test, P < 0.01 for all comparisons.