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Search Results (1,149)

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24 pages, 8231 KiB  
Article
Adaptive Optimization and Dynamic Representation Method for Asynchronous Data Based on Regional Correlation Degree
by Sichao Tang, Yuchen Zhao, Hengyi Lv, Ming Sun, Yang Feng and Zeshu Zhang
Sensors 2024, 24(23), 7430; https://doi.org/10.3390/s24237430 - 21 Nov 2024
Abstract
Event cameras, as bio-inspired visual sensors, offer significant advantages in their high dynamic range and high temporal resolution for visual tasks. These capabilities enable efficient and reliable motion estimation even in the most complex scenes. However, these advantages come with certain trade-offs. For [...] Read more.
Event cameras, as bio-inspired visual sensors, offer significant advantages in their high dynamic range and high temporal resolution for visual tasks. These capabilities enable efficient and reliable motion estimation even in the most complex scenes. However, these advantages come with certain trade-offs. For instance, current event-based vision sensors have low spatial resolution, and the process of event representation can result in varying degrees of data redundancy and incompleteness. Additionally, due to the inherent characteristics of event stream data, they cannot be utilized directly; pre-processing steps such as slicing and frame compression are required. Currently, various pre-processing algorithms exist for slicing and compressing event streams. However, these methods fall short when dealing with multiple subjects moving at different and varying speeds within the event stream, potentially exacerbating the inherent deficiencies of the event information flow. To address this longstanding issue, we propose a novel and efficient Asynchronous Spike Dynamic Metric and Slicing algorithm (ASDMS). ASDMS adaptively segments the event stream into fragments of varying lengths based on the spatiotemporal structure and polarity attributes of the events. Moreover, we introduce a new Adaptive Spatiotemporal Subject Surface Compensation algorithm (ASSSC). ASSSC compensates for missing motion information in the event stream and removes redundant information, thereby achieving better performance and effectiveness in event stream segmentation compared to existing event representation algorithms. Additionally, after compressing the processed results into frame images, the imaging quality is significantly improved. Finally, we propose a new evaluation metric, the Actual Performance Efficiency Discrepancy (APED), which combines actual distortion rate and event information entropy to quantify and compare the effectiveness of our method against other existing event representation methods. The final experimental results demonstrate that our event representation method outperforms existing approaches and addresses the shortcomings of current methods in handling event streams with multiple entities moving at varying speeds simultaneously. Full article
(This article belongs to the Section Optical Sensors)
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<p>Schematic diagram of the human retina model and corresponding event camera pixel circuit.</p>
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<p>(<b>a</b>) We consider the light intensity change signals received by the corresponding pixels as computational elements in the time domain. (<b>b</b>) From the statistical results, it can be seen that the ON polarity ratio varies randomly over the time index.</p>
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<p>This graph represents the time span changes of each event cuboid processed by our algorithm.</p>
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<p>This figure illustrates the time surface of events in the original event stream. For clarity, only the x–t components are shown. Red crosses represent non-main events, and blue dots represent main events. (<b>a</b>) In the time surface described in [<a href="#B50-sensors-24-07430" class="html-bibr">50</a>] (corresponding to Formula (24)), only the occurrence frequency of the nearest events around the main event is considered. Consequently, non-main events with disruptive effects may have significant weight. (<b>b</b>) The local memory time surface corresponding to Formula (26) considers the influence weight of historical events within the current spatiotemporal window. This approach reduces the ratio of non-main events involved in the time surface calculation, better capturing the true dynamics of the event stream. (<b>c</b>) By spatially averaging the time surfaces of all events in adjacent cells, the time surface corresponding to Formula (29) can be further regularized. Due to the spatiotemporal regularization, the influence of non-main events is almost completely suppressed.</p>
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<p>Schematic of the Gromov–Wasserstein Event Discrepancy between the original event stream and the event representation results.</p>
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<p>Illustration of the grid positions corresponding to non-zero entropy values.</p>
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<p>Grayscale images and 3D event stream diagrams for three captured scenarios: (<b>a</b>) Grayscale illustration of the corresponding scenarios; (<b>b</b>) 3D event stream illustration of the corresponding scenarios.</p>
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<p>Grayscale images and 3D event stream diagrams for three captured scenarios: (<b>a</b>) Grayscale illustration of the corresponding scenarios; (<b>b</b>) 3D event stream illustration of the corresponding scenarios.</p>
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<p>The variation of the value of <math display="inline"><semantics> <mrow> <msub> <mrow> <mi>GWED</mi> </mrow> <mi mathvariant="normal">N</mi> </msub> </mrow> </semantics></math> corresponding to each algorithm with different numbers of event samples.</p>
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<p>Illustration of the event stream processing results for Scene A by different algorithms: (<b>a</b>) TORE; (<b>b</b>) ATSLTD; (<b>c</b>) Voxel Grid; (<b>d</b>) MDES; (<b>e</b>) Ours.</p>
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<p>APED data obtained from the event stream processing results for Scene A by different algorithms.</p>
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<p>Illustration of the event stream processing results for Scene B by different algorithms: (<b>a</b>) TORE; (<b>b</b>) ATSLTD; (<b>c</b>) Voxel Grid; (<b>d</b>) MDES; (<b>e</b>) Ours.</p>
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<p>APED data obtained from the event stream processing results for Scene B by different algorithms.</p>
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<p>Illustration of the event stream processing results for Scene C by different algorithms: (<b>a</b>) TORE; (<b>b</b>) ATSLTD; (<b>c</b>) Voxel Grid; (<b>d</b>) MDES; (<b>e</b>) Ours.</p>
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<p>APED data obtained from the event stream processing results for Scene C by different algorithms.</p>
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14 pages, 4005 KiB  
Article
A Directional Enhanced Adaptive Detection Framework for Small Targets
by Chao Li, Yifan Chang, Shimeng Yang, Kaiju Li and Guangqiang Yin
Electronics 2024, 13(22), 4535; https://doi.org/10.3390/electronics13224535 - 19 Nov 2024
Viewed by 227
Abstract
Due to the challenges posed by limited size and features, positional and noise issues, and dataset imbalance and simplicity, small object detection is one of the most challenging tasks in the field of object detection. Consequently, an increasing number of researchers are focusing [...] Read more.
Due to the challenges posed by limited size and features, positional and noise issues, and dataset imbalance and simplicity, small object detection is one of the most challenging tasks in the field of object detection. Consequently, an increasing number of researchers are focusing on this area. In this paper, we propose a Directional Enhanced Adaptive (DEA) detection framework for small targets. This framework effectively combines the detection accuracy advantages of two-stage methods with the detection speed advantages of one-stage methods. Additionally, we introduce a Multi-Scale Object Adaptive Slicing (MASA) module and an improved IoU-based aggregation module that integrate with this framework to enhance detection performance. For better comparison, we use the F1 score as one of the evaluation metrics. The experimental results demonstrate that our DEA framework improves the performance of various backbone detection networks and achieves better comprehensive detection performance than other proposed methods, even though our network has not been trained on the test dataset while others have. Full article
(This article belongs to the Special Issue Deep/Machine Learning in Visual Recognition and Anomaly Detection)
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<p>Illustration of less size and fewer pixels of small target.</p>
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<p>The effect of background noise on small target.</p>
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<p>Overall network structure.</p>
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<p>Original image.</p>
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<p>Sobel operator effect image.</p>
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<p>The detection result of Yolox without DEA framework.</p>
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<p>The detection result with DEA framework.</p>
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20 pages, 2362 KiB  
Article
Machine Learning-Driven GLCM Analysis of Structural MRI for Alzheimer’s Disease Diagnosis
by Maria João Oliveira, Pedro Ribeiro and Pedro Miguel Rodrigues
Bioengineering 2024, 11(11), 1153; https://doi.org/10.3390/bioengineering11111153 - 15 Nov 2024
Viewed by 471
Abstract
Background: Alzheimer’s disease (AD) is a progressive and irreversible neurodegenerative condition that increasingly impairs cognitive functions and daily activities. Given the incurable nature of AD and its profound impact on the elderly, early diagnosis (at the mild cognitive impairment (MCI) stage) and intervention [...] Read more.
Background: Alzheimer’s disease (AD) is a progressive and irreversible neurodegenerative condition that increasingly impairs cognitive functions and daily activities. Given the incurable nature of AD and its profound impact on the elderly, early diagnosis (at the mild cognitive impairment (MCI) stage) and intervention are crucial, focusing on delaying disease progression and improving patients’ quality of life. Methods: This work aimed to develop an automatic sMRI-based method to detect AD in three different stages, namely healthy controls (CN), mild cognitive impairment (MCI), and AD itself. For such a purpose, brain sMRI images from the ADNI database were pre-processed, and a set of 22 texture statistical features from the sMRI gray-level co-occurrence matrix (GLCM) were extracted from various slices within different anatomical planes. Different combinations of features and planes were used to feed classical machine learning (cML) algorithms to analyze their discrimination power between the groups. Results: The cML algorithms achieved the following classification accuracy: 85.2% for AD vs. CN, 98.5% for AD vs. MCI, 95.1% for CN vs. MCI, and 87.1% for all vs. all. Conclusions: For the pair AD vs. MCI, the proposed model outperformed state-of-the-art imaging source studies by 0.1% and non-imaging source studies by 4.6%. These results are particularly significant in the field of AD classification, opening the door to more efficient early diagnosis in real-world settings since MCI is considered a precursor to AD. Full article
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<p>Methodology workflow diagram.</p>
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<p>Skull stripping process in SPM: (<b>a</b>) original image; (<b>b</b>) processed image.</p>
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<p>State-of-the-art comparison with the present study (best <math display="inline"><semantics> <mrow> <mi>a</mi> <mi>c</mi> <mi>c</mi> <mi>u</mi> <mi>r</mi> <mi>a</mi> <mi>c</mi> <mi>y</mi> </mrow> </semantics></math>). For reference: (Shukla et al. 2023 [<a href="#B11-bioengineering-11-01153" class="html-bibr">11</a>]), (Hussain et al. 2020 [<a href="#B22-bioengineering-11-01153" class="html-bibr">22</a>]), (Pirrone et al. 2022 [<a href="#B26-bioengineering-11-01153" class="html-bibr">26</a>]), (Lama et al. 2022 [<a href="#B14-bioengineering-11-01153" class="html-bibr">14</a>]), (Rallabandi and Seetharama 2023 [<a href="#B23-bioengineering-11-01153" class="html-bibr">23</a>]), (Rodrigues et al. 2021 [<a href="#B27-bioengineering-11-01153" class="html-bibr">27</a>]), and (Goenka et al. 2022 [<a href="#B17-bioengineering-11-01153" class="html-bibr">17</a>]).</p>
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14 pages, 1770 KiB  
Article
Deep Learning-Based Slice Thickness Reduction for Computer-Aided Detection of Lung Nodules in Thick-Slice CT
by Jonghun Jeong, Doohyun Park, Jung-Hyun Kang, Myungsub Kim, Hwa-Young Kim, Woosuk Choi and Soo-Youn Ham
Diagnostics 2024, 14(22), 2558; https://doi.org/10.3390/diagnostics14222558 - 14 Nov 2024
Viewed by 321
Abstract
Background/Objectives: Computer-aided detection (CAD) systems for lung nodule detection often face challenges with 5 mm computed tomography (CT) scans, leading to missed nodules. This study assessed the efficacy of a deep learning-based slice thickness reduction technique from 5 mm to 1 mm to [...] Read more.
Background/Objectives: Computer-aided detection (CAD) systems for lung nodule detection often face challenges with 5 mm computed tomography (CT) scans, leading to missed nodules. This study assessed the efficacy of a deep learning-based slice thickness reduction technique from 5 mm to 1 mm to enhance CAD performance. Methods: In this retrospective study, 687 chest CT scans were analyzed, including 355 with nodules and 332 without nodules. CAD performance was evaluated on nodules, to which all three radiologists agreed. Results: The slice thickness reduction technique significantly improved the area under the receiver operating characteristic curve (AUC) for scan-level analysis from 0.867 to 0.902, with a p-value < 0.001, and nodule-level sensitivity from 0.826 to 0.916 at two false positives per scan. Notably, the performance showed greater improvements on smaller nodules than larger nodules. Qualitative analysis confirmed that nodules mistaken for ground glass on 5 mm scans could be correctly identified as part-solid on the refined 1 mm CT, thereby improving the diagnostic capability. Conclusions: Applying a deep learning-based slice thickness reduction technique significantly enhances CAD performance in lung nodule detection on chest CT scans, supporting the clinical adoption of refined 1 mm CT scans for more accurate diagnoses. Full article
(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
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<p>Data flow diagram. This study compares and analyzes the performance of the computer-aided detection system on original 5 mm CT scans and refined 1 mm CT scans obtained through a slice thickness reduction technique.</p>
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<p>Example images of a lung nodule and its annotations. The left image was captured from commercially available software (VUNO-Med LungCT-AI; ver. VN-M-04), and the right image is a magnified example.</p>
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<p>ROC curves for per-scan analysis. (<b>a</b>) Nodule set A without subgroup analysis. (<b>b</b>) Nodule set A with subgroup analysis based on nodule size. (<b>c</b>) Nodule set B without subgroup analysis. (<b>d</b>) Nodule set B with subgroup analysis based on nodule size. The blue and red lines represent CAD results from the original 5 mm and refined 1 mm CT scans, respectively. In the subgroup analyses, dashed and solid lines represent CAD results for nodules smaller than 6 mm and those 6 mm or larger, respectively. ROC, receiver operating characteristic; AUC, area under the ROC curve.</p>
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<p>FROC curves for per-nodule analysis. (<b>a</b>) Nodule set A without subgroup analysis. (<b>b</b>) Nodule set A with subgroup analysis based on nodule size. (<b>c</b>) Nodule set B without subgroup analysis. (<b>d</b>) Nodule set B with subgroup analysis based on nodule size. The red and blue lines represent CAD results from the original 5 mm and refined 1 mm CT scans, respectively. In the subgroup analyses, solid and dashed lines represent CAD results for nodules 6 mm or larger and those smaller than 6 mm, respectively. FROC, free-response receiver operating characteristic; CAD, computer-aided detection.</p>
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<p>Representative images for the quantitative analysis between the original 5 mm CT scan and the refined 1 mm CT scan. (<b>a</b>) Not detected on the original 5 mm CT scan but detected on the refined 1 mm CT scan. (<b>b</b>) Detected on the original 5 mm CT but not detected on the refined 1 mm CT. (<b>c</b>) Classified as a ground-glass nodule on the original 5 mm CT but as a part-solid nodule on the refined 1 mm CT. The cranial direction is toward the left, while the caudal direction is toward the right. The original 5 mm CT images were obtained at 5 mm intervals, while the refined 1 mm CT images were obtained at 1 mm intervals.</p>
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13 pages, 1770 KiB  
Article
Deep Learning Assisted Diagnosis of Chronic Obstructive Pulmonary Disease Based on a Local-to-Global Framework
by Nian Cai, Yiying Xie, Zijie Cai, Yuchen Liang, Yinghong Zhou and Ping Wang
Electronics 2024, 13(22), 4443; https://doi.org/10.3390/electronics13224443 - 13 Nov 2024
Viewed by 324
Abstract
To aid the diagnosis of chronic obstructive pulmonary disease (COPD), a local-to-global deep framework with group attentions and slice-aware loss is designed in this paper, which utilizes the chest CT sequences of the patients as the network input. To fully mine the medical [...] Read more.
To aid the diagnosis of chronic obstructive pulmonary disease (COPD), a local-to-global deep framework with group attentions and slice-aware loss is designed in this paper, which utilizes the chest CT sequences of the patients as the network input. To fully mine the medical hints submerged in the CT slices, two types of group attentions are designed to extract local–global features of the grouped slices. Specifically, in each group, a group local attention block (GLAB) and a group global attention block (GGAB) are designed to extract local features in the CT slices and long-range dependencies among the grouped slices. To alleviate the influence of different numbers of CT slices in the chest CT sequences for different patients, a slice-aware loss is proposed by incorporating a normalized coefficient into the cross-entropy loss. Experimental results indicate that the designed deep model performs a good COPD identification on a real COPD dataset with 96.08% accuracy, 94.12% sensitivity, 97.06% specificity, and 95.32% AUC, which is superior to some existing deep learning methods. Full article
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<p>CT images acquired from (<b>a</b>,<b>b</b>) the patients without COPD, from (<b>c</b>,<b>d</b>) the patients with COPD.</p>
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<p>Number of slices per case in CT dataset.</p>
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<p>Architecture of the designed local-to-global deep framework.</p>
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<p>Confusion matrices for different deep models. (<b>a</b>) Shah et al. [<a href="#B28-electronics-13-04443" class="html-bibr">28</a>]; (<b>b</b>) Ahmed et al. [<a href="#B19-electronics-13-04443" class="html-bibr">19</a>]; (<b>c</b>) Xu et al. [<a href="#B21-electronics-13-04443" class="html-bibr">21</a>]; (<b>d</b>) Kolias et al. [<a href="#B29-electronics-13-04443" class="html-bibr">29</a>]; (<b>e</b>) Humphries et al. [<a href="#B22-electronics-13-04443" class="html-bibr">22</a>]; (<b>f</b>) Varchagall et al. [<a href="#B30-electronics-13-04443" class="html-bibr">30</a>]; (<b>g</b>) Kienzle et al. [<a href="#B31-electronics-13-04443" class="html-bibr">31</a>]; (<b>h</b>) Xie et al. [<a href="#B32-electronics-13-04443" class="html-bibr">32</a>]; (<b>i</b>) Geng et al. [<a href="#B33-electronics-13-04443" class="html-bibr">33</a>]; (<b>j</b>) Ours.</p>
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24 pages, 4499 KiB  
Article
Advancing Parameter Estimation in Differential Equations: A Hybrid Approach Integrating Levenberg–Marquardt and Luus–Jaakola Algorithms
by María de la Luz López-González, Hugo Jiménez-Islas, Carmela Domínguez Campos, Lorenzo Jarquín Enríquez, Francisco Javier Mondragón Rojas and Norma Leticia Flores-Martínez
ChemEngineering 2024, 8(6), 115; https://doi.org/10.3390/chemengineering8060115 - 11 Nov 2024
Viewed by 445
Abstract
This study presents an integrated approach that combines the Levenberg–Marquardt (LM) and Luus–Jaakola (LJ) algorithms to enhance parameter estimation for various applications. The LM algorithm, known for its precision in solving non-linear least squares problems, is effectively paired with the LJ algorithm, a [...] Read more.
This study presents an integrated approach that combines the Levenberg–Marquardt (LM) and Luus–Jaakola (LJ) algorithms to enhance parameter estimation for various applications. The LM algorithm, known for its precision in solving non-linear least squares problems, is effectively paired with the LJ algorithm, a robust stochastic optimization method, to improve accuracy and computational efficiency. This hybrid LM-LJ methodology is demonstrated through several case studies, including the optimization of MESH equations in distillation processes, modeling controlled diffusion in biopolymer films, and analyzing heat and mass transfer during the drying of cylindrical quince slices. By overcoming the convergence issues typical of gradient-based methods and performing global searches without initial parameter bounds, this approach effectively handles complex models and closely aligns simulation results with experimental data. These capabilities highlight the versatility of this approach in engineering and environmental modeling, significantly enhancing parameter estimation in systems governed by differential equations. Full article
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<p>Example of implementation of finite difference discretization for a one-dimensional diffusion–reaction biological system.</p>
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<p>Flowchart of the hybrid strategy composed of the Luus–Jaakola and Levenberg–Marquardt algorithms.</p>
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<p>The implementation of the Luus–Jaakola algorithm for solving MESH equations presents the results for iterations 1, 15, and 50. These results include (<b>a</b>) the molar fraction of liquid propane in the first stage, (<b>b</b>) the outlet temperature, and (<b>c</b>) the flow rate in the first plate.</p>
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<p>Parameter estimation with the hybrid strategy for a 35-node mesh.</p>
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<p>A one-dimensional schematic diagram of the nisin diffusion experiment in an agarose gel.</p>
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<p>Model fitting with experimental data. (<b>a</b>) Analytical solution proposed by Sebti et al. [<a href="#B24-ChemEngineering-08-00115" class="html-bibr">24</a>]. (<b>b</b>) Numerical solution obtained from parameter estimation with the hybrid strategy of the model proposed by Sebti et al. [<a href="#B24-ChemEngineering-08-00115" class="html-bibr">24</a>]. (<b>c</b>) Analytical solution proposed by Flores-Martínez et al. [<a href="#B26-ChemEngineering-08-00115" class="html-bibr">26</a>]. (<b>d</b>) Numerical solution obtained from parameter estimation with the hybrid strategy of the model proposed by Flores-Martínez et al. [<a href="#B26-ChemEngineering-08-00115" class="html-bibr">26</a>].</p>
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<p>Optimized kinetics of lactose conversion to lactic acid.</p>
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<p>One-dimensional numerical model in quince drying.</p>
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<p>Comparison of experimental values versus predicted values in quince drying. (<b>a</b>) Drying temperature and (<b>b</b>) moisture content.</p>
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<p>Comparison of experimental values versus predicted values in quince drying. (<b>a</b>) Drying temperature and (<b>b</b>) moisture content.</p>
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19 pages, 688 KiB  
Article
Advancing Pulmonary Nodule Detection with ARSGNet: EfficientNet and Transformer Synergy
by Maroua Oumlaz, Yassine Oumlaz, Aziz Oukaira, Amrou Zyad Benelhaouare and Ahmed Lakhssassi
Electronics 2024, 13(22), 4369; https://doi.org/10.3390/electronics13224369 - 7 Nov 2024
Viewed by 569
Abstract
Lung cancer, the leading cause of cancer-related deaths globally, presents significant challenges in early detection and diagnosis. The effective analysis of pulmonary medical imaging, particularly computed tomography (CT) scans, is critical in this endeavor. Traditional diagnostic methods, which are manual and time-intensive, underscore [...] Read more.
Lung cancer, the leading cause of cancer-related deaths globally, presents significant challenges in early detection and diagnosis. The effective analysis of pulmonary medical imaging, particularly computed tomography (CT) scans, is critical in this endeavor. Traditional diagnostic methods, which are manual and time-intensive, underscore the need for innovative, efficient, and accurate detection approaches. To address this need, we introduce the Adaptive Range Slice Grouping Network (ARSGNet), a novel deep learning framework that enhances early lung cancer diagnosis through advanced segmentation and classification techniques in CT imaging. ARSGNet synergistically integrates the strengths of EfficientNet and Transformer architectures, leveraging their superior feature extraction and contextual processing capabilities. This hybrid model proficiently handles the complexities of 3D CT images, ensuring precise and reliable lung nodule detection. The algorithm processes CT scans using short slice grouping (SSG) and long slice grouping (LSG) techniques to extract critical features from each slice, culminating in the generation of nodule probabilities and the identification of potential nodular regions. Incorporating shapley additive explanations (SHAP) analysis further enhances model interpretability by highlighting the contributory features. Our extensive experimentation demonstrated a significant improvement in diagnostic accuracy, with training accuracy increasing from 0.9126 to 0.9817. This advancement not only reflects the model’s efficient learning curve but also its high proficiency in accurately classifying a majority of training samples. Given its high accuracy, interpretability, and consistent reduction in training loss, ARSGNet holds substantial potential as a groundbreaking tool for early lung cancer detection and diagnosis. Full article
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<p>Pixel intensity distribution of the training dataset after preprocessing.</p>
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<p>Pixel intensity distribution of the testing dataset after preprocessing.</p>
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<p>Workflow of ARSGNet for Pulmonary nodule detection.</p>
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<p>Loss, Accuracy, Dice Score, and IOU score for ARGSnet in training vs. validation.</p>
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30 pages, 14321 KiB  
Article
Differential Effects of Extracellular Vesicles from Two Different Glioblastomas on Normal Human Brain Cells
by Mary Wang, Arin N. Graner, Bryne Knowles, Charlotte McRae, Anthony Fringuello, Petr Paucek, Michael Gavrilovic, McKenna Redwine, Caleb Hanson, Christina Coughlan, Stacey Grimaldo-Garcia, Brooke Metzger, Vince Bolus, Timothy J. Kopper, Marie Smith, Wenbo Zhou, Morgan Lenz, Aviva Abosch, Steven Ojemann, Kevin O. Lillehei, Xiaoli Yu and Michael W. Graneradd Show full author list remove Hide full author list
Neurol. Int. 2024, 16(6), 1355-1384; https://doi.org/10.3390/neurolint16060103 - 6 Nov 2024
Viewed by 555
Abstract
Background/Objectives: Glioblastomas (GBMs) are dreadful brain tumors with abysmal survival outcomes. GBM extracellular vesicles (EVs) dramatically affect normal brain cells (largely astrocytes) constituting the tumor microenvironment (TME). We asked if EVs from different GBM patient-derived spheroid lines would differentially alter recipient brain cell [...] Read more.
Background/Objectives: Glioblastomas (GBMs) are dreadful brain tumors with abysmal survival outcomes. GBM extracellular vesicles (EVs) dramatically affect normal brain cells (largely astrocytes) constituting the tumor microenvironment (TME). We asked if EVs from different GBM patient-derived spheroid lines would differentially alter recipient brain cell phenotypes. This turned out to be the case, with the net outcome of treatment with GBM EVs nonetheless converging on increased tumorigenicity. Methods: GBM spheroids and brain slices were derived from neurosurgical patient tissues following informed consent. Astrocytes were commercially obtained. EVs were isolated from conditioned culture media by ultrafiltration, concentration, and ultracentrifugation. EVs were characterized by nanoparticle tracking analysis, electron microscopy, biochemical markers, and proteomics. Astrocytes/brain tissues were treated with GBM EVs before downstream analyses. Results: EVs from different GBMs induced brain cells to alter secretomes with pro-inflammatory or TME-modifying (proteolytic) effects. Astrocyte responses ranged from anti-viral gene/protein expression and cytokine release to altered extracellular signal-regulated protein kinase (ERK1/2) signaling pathways, and conditioned media from EV-treated cells increased GBM cell proliferation. Conclusions: Astrocytes/brain slices treated with different GBM EVs underwent non-identical changes in various omics readouts and other assays, indicating “personalized” tumor-specific GBM EV effects on the TME. This raises concern regarding reliance on “model” systems as a sole basis for translational direction. Nonetheless, net downstream impacts from differential cellular and TME effects still led to increased tumorigenic capacities for the different GBMs. Full article
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<p>Proteomes of astrocytes treated with GBM F3-8 EVs or GBM G17-1 EVs. Data were generated in Metaboanalyst 5.0. (<b>A</b>,<b>B</b>) volcano plots, showing significantly differential proteomes between astrocytes treated with GBM EVs (upper-right quadrants, red dots) or control treatments (PBS, upper-left quadrants, blue dots). (<b>A</b>) Astrocytes treated with F3-8 EVs; (<b>B</b>) astrocytes treated with G17- EVs. (<b>C</b>,<b>D</b>) Hierarchical clustering heatmaps from ANOVA statistical analyses utilized normalized data that were standardized by autoscaling features (top 100) with Euclidean distance measurements and clustered by ward. (<b>C</b>) Astrocytes treated with F3-8 EVs; (<b>D</b>) astrocytes treated with G17-1 EVs.</p>
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<p>Ingenuity Pathway Analysis (IPA) highlights of astrocytes proteomes following treatment (“tx’d”) with F3-8 GBM EVs: Canonical Pathways and relevant networks. (<b>A</b>) “Bubble chart” of significant Canonical Pathways (based on −log(<span class="html-italic">p</span>-values)) derived from the proteome of astrocytes treated with GBM F3-8 EVs; broad categories are on the <span class="html-italic">y</span>-axis, and more specific categories are designated in the bubbles (higher scoring categories are denoted). Bubble sizes and color scheme are in the inset. (<b>B</b>) Relevant interactome shown for F3-8 EV-treated astrocytes (Network 4—Cardiovascular Disease; Infectious Disease; Organismal Injury and Abnormalities. Score = 44, 26 Focus Molecules). (<b>C</b>) Relevant interactome shown for F3-8 EV-treated astrocytes (Network 7—Antimicrobial Response; Immunological Disease; Inflammatory Response. Score = 33, 21 Focus Molecules). “Scores” are based on Fisher’s exact test, −log(<span class="html-italic">p</span>-value); “Focus Molecules” are considered focal point generators within the network. The number of genes illustrated is limited to 35 by the algorithm. IPA network legends (node and path design shapes, edges, and their descriptions) are in <a href="#app1-neurolint-16-00103" class="html-app">Supplementary Figure S7</a>.</p>
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<p>IPA highlights of astrocytes proteomes following treatment (“tx’d”) with G17-1 GBM EVs: Canonical Pathways and relevant networks. (<b>A</b>) “Bubble chart” of significant Canonical Pathways derived from the proteome of astrocytes treated with GBM G17-1 EVs (as described in <a href="#neurolint-16-00103-f002" class="html-fig">Figure 2</a>A). (<b>B</b>) Relevant interactome shown for G17-1 EV-treated astrocytes (Network 4—Hereditary Disorder, Ophthalmic Disease, Organismal Injury and Abnormalities. Score = 32, 18 Focus Molecules). (<b>C</b>) Relevant interactome shown for G17-1 EV-treated astrocytes (Network 6—Neurological Disease, Organismal Injury and Abnormalities, Skeletal and Muscular Disorders. Score = 30, 17 Focus Molecules). “Scores” are based on Fisher’s exact test, -log(<span class="html-italic">p</span>-value); “Focus Molecules” are considered focal point generators within the network. Number of genes illustrated is limited to 35 by the algorithm. IPA network legends (node and path design shapes, edges, and their descriptions) are in <a href="#app1-neurolint-16-00103" class="html-app">Supplementary Figure S7</a>.</p>
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<p>GBM F3-8 EVs induce an anti-viral-like response along with increased GFAP expression in recipient astrocytes. (<b>A</b>) Astrocyte transcriptomic analysis (IPA) following treatment with GBM F3-8 EVs and (<b>B</b>) proteomic analysis show RIG-I/DDX58 as the central nodes in the Graphical Summary (shown in the radial layout). (<b>C</b>) STRING analysis of top 10 most highly over-expressed mRNAs in the astrocyte transcriptome following F3-8 EV treatment. (<b>D</b>) Top FunRich Biologic Pathways deduced from the astrocyte transcriptome following F3-8 EV treatment. (<b>E</b>) Following treatment with F3-8 EVs, astrocyte supernatants were collected and subjected to ELISA analysis for type I-III interferons and other cyto/chemokines (PBL Assay Science VeriPlex Human Interferon 9-Plex ELISA kit). Gray bars = astrocytes (normal human astrocytes, NHAs) alone; blue bars = astrocytes treated with EVs from normal human epithelial cell (epi) EVs; red bars = astrocytes treated with F3-8 EVs. * <span class="html-italic">p</span> &lt; 0.05 compared to astrocytes alone; ** <span class="html-italic">p</span> &lt; 0.01 vs. astrocytes alone; *** <span class="html-italic">p</span> &lt; 0.005 vs. astrocytes alone; **** <span class="html-italic">p</span> &lt; 0.0001 vs. astrocytes alone. For epi EV-treated astrocytes, IL6, ** <span class="html-italic">p</span> &lt; 0.01 vs. F3-8 EV-treated astrocytes. One-way ANOVA followed by Tukey’s pairwise multiple comparisons. (<b>F</b>) Western blot validation of innate immune/RNA sensors, GFAP, and (<b>G</b>) IFN-induced molecules, and EVs from cell lines shown (or PBS as control) were incubated with astrocytes for 24 h; cells were lysed, separated on SDS-PAGE, transferred to nitrocellulose, blocked and probed with antibodies against proteins listed, followed by washing and probes with secondary antibodies. That was followed by washing and chemiluminescent development. Molecular weight markers are as indicated. GAPDH was probed to verify comparable loading. Blots are shown as they appear in the FluorChem Q imager. “F3-8 MV” astrocytes were treated with the same protein concentration of “microvesicles” derived from the F3-8 line (see <a href="#app1-neurolint-16-00103" class="html-app">Supplementary Figure S1</a> for isolation details). M2-7 = adult (metastatic) embryonal rhabdomyosarcoma (recurrent; had prior radiation). M6-7 = Grade 4 astrocytoma, IDH mutant (recurrent; had prior radiation).</p>
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<p>Brain slice and astrocyte secretomes following cell tissue and cell treatment with GBM G17-1 EVs. (<b>A</b>) Normal human brain slices were treated with PBS, normal epithelial cell EVs, or GBM G17-1 EVs. Conditioned media supernatants were subjected to Proteome Profiler Human XL Cytokine Arrays (ARY022B; R&amp;D Systems). Spots were quantified by densitometry, averaged, and normalized to tissue weight. Results are displayed as heatmaps. (<b>B</b>) Astrocytes were treated with PBS, astrocyte EVs, or GBM G17-1 EVs. Conditioned media supernatants were subjected to Proteome Profiler Human XL Cytokine Arrays (ARY022B; R&amp;D Systems). Spots were quantified by densitometry, duplicates averaged, and spots normalized to cell count. Results are displayed as heatmaps. (<b>C</b>) Using IPA Comparison Analysis, changes in cyto/chemokine expression of brain slices vs. astrocytes (treated with G17-1 EVs) were categorized by Canonical Pathways, as analyzed by hierarchical clustering by z-score. The top 25 Canonical Pathways compared by heatmaps are shown. (<b>D</b>) Astrocytes were treated with PBS, with EVs from HEK293 cells, or with G17-1 EVs. The conditioned media were transferred to G17-1 cells grown in the same ABM medium, and cell proliferation was measured by MTS assay 24 h later.</p>
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<p>Brain slice and astrocyte secretomes following tissue and cell treatment with GBM G17-1 EVs implicate ERK1/2 signaling. (<b>A</b>) IPA network analysis of the secretome of brain slices treated with GBM G17-1 EVs identified a network with ERK1/2 signaling as the major node when presented in radial layout: “Cell Death and Survival; Cell Development; Inflammatory Response”. Score = 18, 10 Focus Molecules. (<b>B</b>) IPA network analysis of the secretome of astrocytes treated with G17-1 EVs identified a network with ERK1/2 signaling as the major node when presented in radial layout: “Cardiovascular System Development and Function; Hematological System Development and Function; Inflammatory Response”. Score = 18, 11 Focus Molecules. Score and Focus Molecule definitions are the same as in <a href="#neurolint-16-00103-f002" class="html-fig">Figure 2</a> and <a href="#neurolint-16-00103-f003" class="html-fig">Figure 3</a> (see also <a href="#app1-neurolint-16-00103" class="html-app">Supplementary Figure S7</a>). (<b>C</b>) Equal numbers of astrocytes were left untreated, or were treated with the ERK1/2 inhibitor SCH772984 (1 mM) for 4 h, and then ± G17-1 EVs for 24 h. Astrocytes were lysed, and lysates subjected to a Creative Biolabs Human Phospho-Kinase Antibody Array (AbAr-0225-YC). Spots were quantified by densitometry and duplicates averaged, and values were represented by heatmaps. (<b>D</b>) Astrocyte culture supernatants (from cells treated as in (<b>C</b>)) were subjected to the same ELISA as in <a href="#neurolint-16-00103-f004" class="html-fig">Figure 4</a>E; only TNFA and IL6 results are shown, along with a POSTN ELISA (ELH-POSTN; RayBiotech). For TNFA, **** <span class="html-italic">p</span> &lt; 0.0001 G17-1 EVs vs. G17-1 EVs and ERKi; vs. PBS; vs. PBS and ERKi. AA <span class="html-italic">p</span> = 0.0078 G17-1 EVs and ERKi vs. PBS and ERKi. CCCC <span class="html-italic">p</span> &lt; 0.001 PBS vs. PBS and ERKi. For IL6, **** <span class="html-italic">p</span> &lt; 0.0001 G17-1 EVs and ERKi vs. G17-1 EVs; vs. PBS; vs. PBS and ERKi. @@ <span class="html-italic">p</span> = 0.0012 PBS and ERKi vs. G17-1 EVs. For POSTN, ** <span class="html-italic">p</span> &lt; 0.003 G17-1 EVs vs. PBS; vs. PBS and ERKi; * <span class="html-italic">p</span> &lt; 0.05 G17-1 EVs vs. G17-1 EVs and ERKi. ANOVA followed by Tukey’s pairwise multiple comparisons.</p>
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<p>Proteases and activities in GBM EVs and astrocyte or brain-slice-conditioned media following GBM EV treatment. (<b>A</b>) Equal numbers of astrocytes were treated with PBS, GBM F3-8 EVs, or GBM G17-1 EVs for 24 h. Conditioned media supernatants were collected and used to probe Proteome Profiler Human Protease Arrays (#ARY021B; R&amp;D Systems). Spots were quantified by densitometry and duplicates averaged, and values were represented by heatmaps. (<b>B</b>) Collagenase/MMP activity was measured by abcam MMP Activity Assay Kits (Cat # ab112146); astrocytes were treated with the tumor EVs listed (PBS as a control; F3-8, G17-1, M16-8, M6-7) for 24 h. Conditioned media were harvested, and assayed over a 1 h period; **** <span class="html-italic">p</span> &lt; 0.0001 G17-1 EV treatment vs. all others. (<b>C</b>) Collagenase/MMP activity of PBS only (blue line), astrocyte-conditioned medium following PBS treatment (red line), G17-1 EVs only (green line, same concentration as used in astrocyte treatment), or astrocyte-conditioned medium following G17-1 EV treatment (purple line). **** <span class="html-italic">p</span> &lt; 0.0001 G17-1 EV treatment of astrocytes vs. either PBS; *** <span class="html-italic">p</span> &lt; 0.001 G17-1 EVs alone vs. either PBS; ** <span class="html-italic">p</span> &lt; 0.01 G17-1 EV treatment of astrocytes vs. G17-1 EVs alone. (<b>D</b>) Collagenase/MMP activity of PBS only (blue line), astrocyte-conditioned medium following PBS treatment (red line), F3-8 EVs only (green line, same concentration as used in astrocyte treatment), or astrocyte-conditioned medium following F3-8 EV treatment (purple line). **** <span class="html-italic">p</span> &lt; 0.0001 F3-8 EVs only vs. all others. ANOVA followed by Tukey’s pairwise multiple comparisons. E: Brain slices were treated G17-1 EVs (red line), epithelial cell EVs (blue line), or PBS (gray line) for 24 h. Brain-slice-conditioned media were assayed in a gelatinase assay (EnzChek™ Gelatinase/Collagenase Assay Kit; cat # E12055; ThermoFisher) over 14 h. G17-1 EV gelatinase activity was measured directly (orange line, same concentration as used in astrocyte treatment) over the same period. (<b>F</b>) Brain slices were treated as in (<b>E</b>) and were imaged in two-photon excitation microscopy through 10 μm depths to reveal matrix degradation (G17-1 EV treatment panels, right side). Top row = representative single plane, multiple deep focal plane imaging, 2-D maximum intensity projection image size = 1024 × 1024 pixel resolution; bottom row = axial scanning reconstructed Z-stack series, 3-D Intensity projection (XY image size x: 1024, y: 1024, Z: 33, 8-bit) was reconstructed from the Z-stack (sample (x: 353.90 μm, y: 353.90 μm, z: 10.65 μm, 33 slides).</p>
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19 pages, 12980 KiB  
Article
Study on the “Two-Zone” Heights in Lower Slice Mining Under Thick Alluvium and Thin Bedrock
by Xiaowei Lu, Jingyu Jiang, Wen Wang and Haibo Cao
Appl. Sci. 2024, 14(22), 10128; https://doi.org/10.3390/app142210128 - 5 Nov 2024
Viewed by 471
Abstract
The extraction of thin bedrock coal seams with thick alluvium poses a challenging issue in the realm of coal safety production in China. Especially for mining under aquifers, knowing the development height of water-conducting fracture zones above the goaf is crucial for coal [...] Read more.
The extraction of thin bedrock coal seams with thick alluvium poses a challenging issue in the realm of coal safety production in China. Especially for mining under aquifers, knowing the development height of water-conducting fracture zones above the goaf is crucial for coal mine safety and production. Taking the 11092 working face of lower slice mining in Zhaogu No. 1 Mine as an example, the failure transfer process of the overlying strata is analyzed first. On this basis, the development height of the water-conducting fracture zone is predicted using empirical formulas and the BP neural network. According to the empirical formula, the height of the roof caving zone ranges from 6.93 m to 27.72 m, while the height of the water-conducting fracture zone ranges from 22.17 m to 71.73 m. The BP neural network predicts that the development height of the water-conducting fracture zone in the working face after mining is 56.83 m. CDEM numerical simulation is employed to analyze the development height of two zones of overburden rock. The findings indicate that with a mining height of 2.5 m and a cumulative mining height of 6 m, the maximum caving ratio is 2.61. It is observed that for a cumulative mining thickness of less than 6 m, a bedrock thickness of not less than 30 m, and a clay layer thickness exceeding 5 m, the clay layer effectively obstructs the upward development of the water-conducting fracture zone. Finally, the prediction results of the development height of the two zones of overlying strata in the working face are verified by using the height observation method on the underground water-conducting fracture zone and the borehole peeping method. In conclusion, the height of the overlying strata after mining the lower slice working face in the first panel of the east can be used as a basis for determining the thickness of coal (rock) pillars for waterproofing and sand control safety during the mining of lower slice working faces in mines. Full article
(This article belongs to the Special Issue Advances in Green Coal Mining Technologies)
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<p>Traffic location of coal mine.</p>
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<p>East panel layout and bedrock thickness contour map.</p>
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<p>Near-north–south loose layer (aquifuge) group section comparison.</p>
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<p>Roadway layout of 11092 working face.</p>
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<p>The transfer state of overlying strata on the working face.</p>
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<p>Overburden rock failure transfer process and its stage division.</p>
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<p>Different-state-structure rock mechanics model.</p>
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<p>BP neural network training results.</p>
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<p>Sample fitting situation.</p>
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<p>Simulation of strata distribution.</p>
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<p>Strike overburden structure after upper slice mining. (<b>a</b>) Working face advancing 80 m; (<b>b</b>) working face advancing 120 m; (<b>c</b>) working face advancing 180 m.</p>
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<p>Strike overburden structure after lower slice mining. (<b>a</b>) Working face advancing 80 m; (<b>b</b>) working face advancing 120 m; (<b>c</b>) working face advancing 180 m.</p>
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<p>Observation method for the height of the water-conducting fractured zone.</p>
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<p>Observation borehole layout.</p>
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<p>Statistical curve of drilling fluid leakage.</p>
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<p>Observation hole peep results. (<b>a</b>) Peeping results of 1# observation hole; (<b>b</b>) peeping results of 4# observation hole.</p>
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<p>‘Two zones’ development height results. (<b>a</b>) Development height of caving zone; (<b>b</b>) development height of water flowing fractured zone.</p>
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10 pages, 2991 KiB  
Article
The Impact of Medial Meniscal Extrusion on Cartilage of the Medial Femorotibial Joint—A Retrospective Analysis Based on Quantitative T2 Mapping at 3.0T
by Paul Lennart Hoppe, Moritz Priol, Bernhard Springer, Wenzel Waldstein-Wartenberg, Christoph Böhler, Reinhard Windhager, Siegfried Trattnig and Sebastian Apprich
J. Clin. Med. 2024, 13(22), 6628; https://doi.org/10.3390/jcm13226628 - 5 Nov 2024
Viewed by 517
Abstract
Background/Objectives: The aim of this study was the investigation of any correlation between medial meniscal extrusion (MME) and T2 relaxation times. Furthermore, the impact of different meniscal morphologies on the femoral cartilage was assessed. Methods: Fifty-nine knees of fifty-five patients (twenty-four [...] Read more.
Background/Objectives: The aim of this study was the investigation of any correlation between medial meniscal extrusion (MME) and T2 relaxation times. Furthermore, the impact of different meniscal morphologies on the femoral cartilage was assessed. Methods: Fifty-nine knees of fifty-five patients (twenty-four female, thirty-one male) with a mean age of 33.7 ± 9.2 years and without risk factors for MME or osteoarthritis were examined in a 3.0T MRI. MME was assessed quantitatively in accordance with BLOKS score. T2 maps were calculated from sagittal 2D MESE sequences. The region of interest was defined as the load-bearing cartilage at the medial femoral condyle and analysis was performed on two consecutive slices. T2 values were correlated to MME; furthermore, mean T2 values were compared in different grades of MME. Results: T2 values showed a strong correlation with increasing MME (r = 0.635; p < 0.001) in an exponential pattern. Analogously, knees with MME ≥ 3 mm showed statistically significant higher T2 values (p < 0.001) compared to knees with MME ≤ 2 mm and 2.1–2.9 mm; between the latter two, no differences in T2 values were found. Conclusions: T2 values showed a strong correlation with increasing MME. Consequently, MME ≥ 3 mm has a detectable impact on the cartilage of the femur. Full article
(This article belongs to the Section Orthopedics)
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<p>Depiction of measurement of MME, marked in red and labeled with delta, alongside a table of MME categorization according to the Boston–Leeds Osteoarthritis Knee Score (BLOKS).</p>
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<p>MME measured in coronal 2D PD weighted, fat-saturated TSE sequences and T2 mapping in sagittal 2D MESE T2 sequences illustrated in a healthy knee with a meniscal extrusion of 1.6 mm (<b>a</b>) and a mean T2 value of 38.4 ms (<b>b</b>), as well as in a pathological knee with a meniscal extrusion of 4.5 mm (<b>c</b>) with a corresponding T2 value of 63.9 ms (<b>d</b>).</p>
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<p>Flow chart of patient selection–exclusion criteria in blue boxes.</p>
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<p>Scatterplot for the correlation of MME and T2 values of the femoral cartilage at the medial condyle showing best concurrence with a square function in curve fitting.</p>
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<p>Boxplot illustrating the T2 values of different BLOKS grades (<b>a</b>), and T2 values of different meniscal morphologies (<b>b</b>); statistically higher T2 values are marked with *.</p>
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19 pages, 8257 KiB  
Article
Basic Cells Special Features and Their Influence on Global Transport Properties of Long Periodic Structures
by Luna R. N. Oliveira and Marcos G. E. da Luz
Entropy 2024, 26(11), 942; https://doi.org/10.3390/e26110942 - 3 Nov 2024
Viewed by 416
Abstract
In this contribution, we address quantum transport in long periodic arrays whose basic cells, localized potentials U(x), display certain particular features. We investigate under which conditions these “local” special characteristics can influence the tunneling behavior through the full structure. [...] Read more.
In this contribution, we address quantum transport in long periodic arrays whose basic cells, localized potentials U(x), display certain particular features. We investigate under which conditions these “local” special characteristics can influence the tunneling behavior through the full structure. As the building blocks, we consider two types of U(x)s: combinations of either Pöschl–Teller, U0/cosh2[αx], potentials (for which the reflection and transmission coefficients are known analytically) or Gaussian-shaped potentials. For the latter, we employ an improved potential slicing procedure using basic barriers, like rectangular, triangular and trapezoidal, to approximate U(x) and thus obtain its scattering amplitudes. By means of a recently derived method, we discuss scattering along lattices composed of a number, N, of these U(x)s. We find that near-resonance energies of an isolated U(x) do impact the corresponding energy bands in the limit of very large Ns, but only when the cell is spatially asymmetric. Then, there is a very narrow opening (defect or rip) in the system conduction quasi-band, corresponding to the energy of the U(x) quasi-state. Also, for specific U0’s of a single Pöschl–Teller well, one has 100% transmission for any incident E>0. For the U(x) parameters rather close to such a condition, the associated array leads to a kind of “reflection comb” for large Ns; |TN(k)|2 is not close to one only at very specific values of k, when |TN|20. Finally, the examples here—illustrating how the anomalous transport comportment in finite but long lattices can be inherited from certain singular aspects of the U(x)s—are briefly discussed in the context of known effects in the literature, notably for lattices with asymmetric cells. Full article
(This article belongs to the Special Issue Tunneling in Complex Systems)
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<p>(<b>a</b>) Schematics of a continuous localized potential approximated by a set of <math display="inline"><semantics> <mi mathvariant="script">N</mi> </semantics></math> elementary (here rectangular) barriers. The darker gray potential indicates the <span class="html-italic">n</span>-th barrier, with its reflection and transmission coefficients shown. (<b>b</b>) An array of <math display="inline"><semantics> <mi mathvariant="script">M</mi> </semantics></math> arbitrary localized, compact support potentials.</p>
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<p>(<b>a</b>) Distinct CBBs that approximate a Gaussian potential: CBB-tt (I), CBB-trt (II), CBB-t<math display="inline"><semantics> <mrow> <mover> <mi mathvariant="normal">t</mi> <mo>̃</mo> </mover> </mrow> </semantics></math>r<math display="inline"><semantics> <mrow> <mover> <mi mathvariant="normal">t</mi> <mo>̃</mo> </mover> </mrow> </semantics></math>t (III) and CBB-t<math display="inline"><semantics> <mrow> <mover> <mi mathvariant="normal">t</mi> <mo>̃</mo> </mover> </mrow> </semantics></math><math display="inline"><semantics> <mrow> <mover> <mi mathvariant="normal">t</mi> <mo>̃</mo> </mover> </mrow> </semantics></math>r<math display="inline"><semantics> <mrow> <mover> <mi mathvariant="normal">t</mi> <mo>̃</mo> </mover> </mrow> </semantics></math><math display="inline"><semantics> <mrow> <mover> <mi mathvariant="normal">t</mi> <mo>̃</mo> </mover> </mrow> </semantics></math>t (IV). Here, CBB-abc… means that the CBB is formed, from left to right, by the sequence a, b, c, … of juxtaposed barriers; moreover, t, <math display="inline"><semantics> <mrow> <mover> <mi mathvariant="normal">t</mi> <mo>̃</mo> </mover> </mrow> </semantics></math> and r stand, respectively, for triangular, trapezoidal and rectangular shapes. The parameters are those in <a href="#entropy-26-00942-t001" class="html-table">Table 1</a>. (<b>b</b>) As a function of incident energy, the <math display="inline"><semantics> <mrow> <mrow> <mo>|</mo> </mrow> <msub> <mi>T</mi> <mrow> <mi>C</mi> <mi>B</mi> <mi>B</mi> </mrow> </msub> <msup> <mrow> <mo>|</mo> </mrow> <mn>2</mn> </msup> </mrow> </semantics></math>s of CBBs III and IV are compared with the Gaussian potential actual transmission probability, calculated with the Wronskian method (WM) in Ref. [<a href="#B30-entropy-26-00942" class="html-bibr">30</a>,<a href="#B31-entropy-26-00942" class="html-bibr">31</a>]. The agreement is very good for both CBBs. In the inset is the same type of comparison, but for CBBs I and II.</p>
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<p>The exact probability transmission versus <span class="html-italic">k</span> for the Pöschl–Teller potential compared with that of the CBB (whose composition is shown in the inset). For the parameter values, see main text.</p>
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<p>(<b>a</b>) Schematics of two successive Gaussians (dashed curves) belonging to an array of <span class="html-italic">N</span> localized barriers. As indicated, each Gaussian is approximated by a proper CBB-IV. The full transmission probability versus <span class="html-italic">k</span> for the case of (<b>b</b>) <math display="inline"><semantics> <mrow> <mi>N</mi> <mo>=</mo> <mn>2</mn> </mrow> </semantics></math> and (<b>c</b>) <math display="inline"><semantics> <mrow> <mi>N</mi> <mo>=</mo> <mn>3</mn> </mrow> </semantics></math>, calculated from the present approach using the CBB-IV and from the transfer matrix method (TM) in [<a href="#B38-entropy-26-00942" class="html-bibr">38</a>] (the corresponding curves have been digitalized directly from Ref. [<a href="#B38-entropy-26-00942" class="html-bibr">38</a>]). Each Gaussian reads <math display="inline"><semantics> <mrow> <msub> <mi>U</mi> <mi>G</mi> </msub> <mrow> <mo>(</mo> <mi>x</mi> <mo>)</mo> </mrow> <mo>=</mo> <mo form="prefix">exp</mo> <mrow> <mo>[</mo> <mo>−</mo> <msup> <mi>x</mi> <mn>2</mn> </msup> <mo>]</mo> </mrow> </mrow> </semantics></math>; in addition, <math display="inline"><semantics> <mrow> <mover accent="true"> <mi>μ</mi> <mo>¯</mo> </mover> <mo>=</mo> <mn>8</mn> </mrow> </semantics></math>. For the first four BBs of the CBB-IV, namely t<math display="inline"><semantics> <mrow> <mover> <mi mathvariant="normal">t</mi> <mo>̃</mo> </mover> </mrow> </semantics></math><math display="inline"><semantics> <mrow> <mover> <mi mathvariant="normal">t</mi> <mo>̃</mo> </mover> </mrow> </semantics></math>r, the parameters are <math display="inline"><semantics> <mrow> <mi>w</mi> <mo>=</mo> <mn>0.6</mn> <mo>,</mo> <mn>0.5</mn> <mo>,</mo> <mn>0.9</mn> <mo>,</mo> <mn>0.4</mn> </mrow> </semantics></math>, <math display="inline"><semantics> <mrow> <msub> <mi>U</mi> <mi>a</mi> </msub> <mo>=</mo> <mn>0</mn> <mo>,</mo> <mn>0.06</mn> <mo>,</mo> <mn>0.3</mn> </mrow> </semantics></math>, <math display="inline"><semantics> <mrow> <msub> <mi>U</mi> <mi>b</mi> </msub> <mo>=</mo> <mn>0.06</mn> <mo>,</mo> <mn>0.3</mn> <mo>,</mo> <mn>1</mn> </mrow> </semantics></math> and <math display="inline"><semantics> <mrow> <mover accent="true"> <mi>U</mi> <mo stretchy="false">˜</mo> </mover> <mo>=</mo> <mn>1</mn> </mrow> </semantics></math>. To align with Ref. [<a href="#B38-entropy-26-00942" class="html-bibr">38</a>], specifically for this example, we set <math display="inline"><semantics> <mrow> <mn>2</mn> <mi>μ</mi> <mo>/</mo> <msup> <mo>ℏ</mo> <mn>2</mn> </msup> <mo>=</mo> <mn>1</mn> </mrow> </semantics></math>.</p>
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<p>(<b>a</b>) The four CBB-IVs that model the continuous Gaussian potentials, forming arrays of <math display="inline"><semantics> <mrow> <mi>N</mi> <mo>=</mo> <msup> <mn>10</mn> <mn>4</mn> </msup> </mrow> </semantics></math> barriers. (<b>b</b>) Illustration of two successive Gaussians composing a lattice in the cases of <math display="inline"><semantics> <mrow> <mi>σ</mi> <mo>=</mo> <mn>0.1</mn> </mrow> </semantics></math> and <math display="inline"><semantics> <mrow> <mi>σ</mi> <mo>=</mo> <mn>0.6</mn> </mrow> </semantics></math>. The parameters are always chosen such that <math display="inline"><semantics> <mrow> <mi>L</mi> <mo>=</mo> <mover> <mi>μ</mi> <mo>¯</mo> </mover> <mo>−</mo> <mover> <mi>w</mi> <mo>¯</mo> </mover> <mo>=</mo> <mn>1</mn> </mrow> </semantics></math>. Transmission probabilities as a function of <span class="html-italic">k</span> for the arrays with (<b>c</b>) <math display="inline"><semantics> <mrow> <mi>σ</mi> <mo>=</mo> <mn>0.1</mn> </mrow> </semantics></math>, (<b>d</b>) <math display="inline"><semantics> <mrow> <mi>σ</mi> <mo>=</mo> <mn>0.2</mn> </mrow> </semantics></math>, (<b>e</b>) <math display="inline"><semantics> <mrow> <mi>σ</mi> <mo>=</mo> <mn>0.4</mn> </mrow> </semantics></math>, (<b>f</b>) <math display="inline"><semantics> <mrow> <mi>σ</mi> <mo>=</mo> <mn>0.6</mn> </mrow> </semantics></math>. The dashed curves represent the transmission probability for the corresponding single CBB-IV.</p>
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<p>(<b>a</b>) Transmission probability as a function of <span class="html-italic">k</span> for a single Pöschl–Teller well with <math display="inline"><semantics> <mrow> <mi>α</mi> <mo>=</mo> <mn>1</mn> </mrow> </semantics></math> and <math display="inline"><semantics> <msub> <mi>U</mi> <mn>0</mn> </msub> </semantics></math> equal to <math display="inline"><semantics> <mrow> <mo>−</mo> <mn>1.000</mn> </mrow> </semantics></math>, <math display="inline"><semantics> <mrow> <mo>−</mo> <mn>0.891</mn> </mrow> </semantics></math>, <math display="inline"><semantics> <mrow> <mo>−</mo> <mn>0.990</mn> </mrow> </semantics></math> and <math display="inline"><semantics> <mrow> <mo>−</mo> <mn>1.089</mn> </mrow> </semantics></math>. For the three latter cases, being the basic cells of finite periodic lattices with <math display="inline"><semantics> <mrow> <mi>N</mi> <mo>=</mo> <msup> <mn>10</mn> <mn>4</mn> </msup> </mrow> </semantics></math> and <math display="inline"><semantics> <mrow> <mn>2</mn> <mi>c</mi> <mo>=</mo> <mn>14</mn> </mrow> </semantics></math> (which is the separation between the centers of two successive wells; inset in (<b>a</b>)), the corresponding <math display="inline"><semantics> <mrow> <mrow> <mo>|</mo> </mrow> <msub> <mi>T</mi> <mi>N</mi> </msub> <msup> <mrow> <mo>|</mo> </mrow> <mn>2</mn> </msup> </mrow> </semantics></math> versus <span class="html-italic">k</span> plots are presented in (<b>b</b>–<b>d</b>).</p>
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<p>Similar to <a href="#entropy-26-00942-f006" class="html-fig">Figure 6</a>b, but for <math display="inline"><semantics> <mrow> <msub> <mi>U</mi> <mn>0</mn> </msub> <mo>=</mo> <mo>−</mo> <mn>0.999</mn> </mrow> </semantics></math> and <math display="inline"><semantics> <mrow> <mi>N</mi> <mo>=</mo> <msup> <mn>10</mn> <mn>7</mn> </msup> </mrow> </semantics></math>. The extremely narrow (basically spikes) forbidden quasi-bands occur around the wavenumbers <math display="inline"><semantics> <mrow> <mn>0.109</mn> </mrow> </semantics></math>, <math display="inline"><semantics> <mrow> <mn>0.368</mn> </mrow> </semantics></math>, <math display="inline"><semantics> <mrow> <mn>0.621</mn> </mrow> </semantics></math>, <math display="inline"><semantics> <mrow> <mn>0.868</mn> </mrow> </semantics></math>, <math display="inline"><semantics> <mrow> <mn>1.11</mn> </mrow> </semantics></math>, <math display="inline"><semantics> <mrow> <mn>1.35</mn> </mrow> </semantics></math>, <math display="inline"><semantics> <mrow> <mn>1.49</mn> </mrow> </semantics></math>, <math display="inline"><semantics> <mrow> <mn>1.72</mn> </mrow> </semantics></math>, <math display="inline"><semantics> <mrow> <mn>1.95</mn> </mrow> </semantics></math>. Apart from for the spikes, there are almost no fluctuations from <math display="inline"><semantics> <mrow> <mrow> <mo>|</mo> </mrow> <msub> <mi>T</mi> <mi>N</mi> </msub> <msup> <mrow> <mo>|</mo> </mrow> <mn>2</mn> </msup> <mo>≈</mo> <mn>1</mn> </mrow> </semantics></math>.</p>
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<p>(<b>a</b>) For the Gaussian ABB discussed in the main text (and approximated by two CBB-IVs, inset) of parameters <math display="inline"><semantics> <mrow> <msub> <mi>U</mi> <mn>0</mn> </msub> <mo>=</mo> <mn>4</mn> <mo>,</mo> <mspace width="0.166667em"/> <mi>σ</mi> <mo>=</mo> <mn>0.1</mn> </mrow> </semantics></math> (left, the red graphic in the inset) and <math display="inline"><semantics> <mrow> <msub> <mi>U</mi> <mn>0</mn> </msub> <mo>=</mo> <mn>0.66</mn> <mo>,</mo> <mspace width="0.166667em"/> <mi>σ</mi> <mo>=</mo> <mn>0.6</mn> </mrow> </semantics></math> (right, the blue graphic in the inset) barriers, the resulting transmission probability, <math display="inline"><semantics> <mrow> <mrow> <mo>|</mo> </mrow> <msub> <mi>T</mi> <mn>1</mn> </msub> <msup> <mrow> <mo>|</mo> </mrow> <mn>2</mn> </msup> </mrow> </semantics></math>, shown as a function of <span class="html-italic">k</span>. For the <span class="html-italic">N</span> finite periodic lattices, the corresponding <math display="inline"><semantics> <mrow> <mrow> <mo>|</mo> </mrow> <msub> <mi>T</mi> <mi>N</mi> </msub> <msup> <mrow> <mo>|</mo> </mrow> <mn>2</mn> </msup> <mrow> <mo>(</mo> <mi>k</mi> <mo>)</mo> </mrow> </mrow> </semantics></math> are displayed in (<b>b</b>) <math display="inline"><semantics> <mrow> <mi>N</mi> <mo>=</mo> <mn>5</mn> </mrow> </semantics></math>, (<b>c</b>) <math display="inline"><semantics> <mrow> <mi>N</mi> <mo>=</mo> <mn>10</mn> </mrow> </semantics></math>, (<b>d</b>) <math display="inline"><semantics> <mrow> <mi>N</mi> <mo>=</mo> <mn>20</mn> </mrow> </semantics></math>, (<b>e</b>) <math display="inline"><semantics> <mrow> <mi>N</mi> <mo>=</mo> <mn>50</mn> </mrow> </semantics></math>, (<b>f</b>) <math display="inline"><semantics> <mrow> <mi>N</mi> <mo>=</mo> <msup> <mn>10</mn> <mn>4</mn> </msup> </mrow> </semantics></math>. In all cases, the distance between successive cells (formed by two CBB-IVs) are equal to one. A blow up of (<b>f</b>) in a particular <span class="html-italic">k</span> interval emcopassing <math display="inline"><semantics> <msub> <mi>k</mi> <mrow> <mi>r</mi> <mi>e</mi> <mi>s</mi> </mrow> </msub> </semantics></math> is shown in (<b>g</b>).</p>
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<p>(<b>a</b>) Schematics of a cell formed by two Pöschl–Teller barriers, where the distance between them as a function of <span class="html-italic">k</span> is <math display="inline"><semantics> <mrow> <mi>L</mi> <mrow> <mo>(</mo> <mi>k</mi> <mo>)</mo> </mrow> <mo>=</mo> <msub> <mi>L</mi> <mn>1</mn> </msub> <mrow> <mo>(</mo> <mi>k</mi> <mo>)</mo> </mrow> <mo>/</mo> <mn>2</mn> <mo>+</mo> <msub> <mi>L</mi> <mn>2</mn> </msub> <mrow> <mo>(</mo> <mi>k</mi> <mo>)</mo> </mrow> <mo>/</mo> <mn>2</mn> </mrow> </semantics></math>. The transmission probability of a single cell, <math display="inline"><semantics> <mrow> <mrow> <mo>|</mo> </mrow> <msub> <mi>T</mi> <mn>1</mn> </msub> <msup> <mrow> <mrow> <mo>(</mo> <mi>k</mi> <mo>)</mo> </mrow> <mo>|</mo> </mrow> <mn>2</mn> </msup> </mrow> </semantics></math>, and of a lattice with <math display="inline"><semantics> <mrow> <mi>N</mi> <mo>=</mo> <msup> <mn>10</mn> <mn>4</mn> </msup> </mrow> </semantics></math> cells, <math display="inline"><semantics> <mrow> <mrow> <mo>|</mo> </mrow> <msub> <mi>T</mi> <mi>N</mi> </msub> <msup> <mrow> <mrow> <mo>(</mo> <mi>k</mi> <mo>)</mo> </mrow> <mo>|</mo> </mrow> <mn>2</mn> </msup> </mrow> </semantics></math>, are shown for the cases of (<b>b</b>) <math display="inline"><semantics> <mrow> <msub> <mi>U</mi> <mrow> <mn>0</mn> <mo>,</mo> <mn>1</mn> </mrow> </msub> <mo>=</mo> <msub> <mi>U</mi> <mrow> <mn>0</mn> <mo>,</mo> <mn>2</mn> </mrow> </msub> <mo>=</mo> <mn>0.9</mn> </mrow> </semantics></math>, (<b>c</b>) <math display="inline"><semantics> <mrow> <msub> <mi>U</mi> <mrow> <mn>0</mn> <mo>,</mo> <mn>1</mn> </mrow> </msub> <mo>=</mo> <msub> <mi>U</mi> <mrow> <mn>0</mn> <mo>,</mo> <mn>2</mn> </mrow> </msub> <mo>=</mo> <mn>0.8</mn> </mrow> </semantics></math>, (<b>d</b>) <math display="inline"><semantics> <mrow> <msub> <mi>U</mi> <mrow> <mn>0</mn> <mo>,</mo> <mn>1</mn> </mrow> </msub> <mo>=</mo> <mn>0.9</mn> </mrow> </semantics></math>, <math display="inline"><semantics> <mrow> <msub> <mi>U</mi> <mrow> <mn>0</mn> <mo>,</mo> <mn>2</mn> </mrow> </msub> <mo>=</mo> <mn>0.8</mn> </mrow> </semantics></math>, (<b>e</b>) <math display="inline"><semantics> <mrow> <msub> <mi>U</mi> <mrow> <mn>0</mn> <mo>,</mo> <mn>1</mn> </mrow> </msub> <mo>=</mo> <mn>0.9</mn> </mrow> </semantics></math>, <math display="inline"><semantics> <mrow> <msub> <mi>U</mi> <mrow> <mn>0</mn> <mo>,</mo> <mn>2</mn> </mrow> </msub> <mo>=</mo> <mn>0.6</mn> </mrow> </semantics></math>. In all cases, <math display="inline"><semantics> <mrow> <mi>α</mi> <mo>=</mo> <mn>1</mn> </mrow> </semantics></math> and <math display="inline"><semantics> <mrow> <mi>c</mi> <mo>=</mo> <mn>5</mn> </mrow> </semantics></math>. The transmission probabilities for the isolated left and right barriers are also displayed.</p>
Full article ">Figure A1
<p>(<b>a</b>) Illustration of a building block formed by two rectangular barriers, with widths <math display="inline"><semantics> <mrow> <msub> <mi>w</mi> <mn>1</mn> </msub> <mo>,</mo> <msub> <mi>w</mi> <mn>2</mn> </msub> </mrow> </semantics></math> and heights <math display="inline"><semantics> <mrow> <msub> <mover accent="true"> <mi>U</mi> <mo stretchy="false">˜</mo> </mover> <mn>1</mn> </msub> <mo>,</mo> <msub> <mover accent="true"> <mi>U</mi> <mo stretchy="false">˜</mo> </mover> <mn>2</mn> </msub> </mrow> </semantics></math>. Graph of the transmission probability in terms of the wavenumber <span class="html-italic">k</span>, when we consider (<b>b</b>) a symmetrical and (<b>c</b>) an asymmetrical cell. In (<b>b</b>), <math display="inline"><semantics> <mrow> <msub> <mover accent="true"> <mi>U</mi> <mo stretchy="false">˜</mo> </mover> <mn>2</mn> </msub> <mo>=</mo> <mn>2</mn> </mrow> </semantics></math>, and in (<b>c</b>), <math display="inline"><semantics> <mrow> <msub> <mover accent="true"> <mi>U</mi> <mo stretchy="false">˜</mo> </mover> <mn>1</mn> </msub> <mo>=</mo> <mn>2.2</mn> </mrow> </semantics></math>. The remain parameters are <math display="inline"><semantics> <mrow> <msub> <mi>w</mi> <mn>1</mn> </msub> <mo>=</mo> <msub> <mi>w</mi> <mn>2</mn> </msub> <mo>=</mo> <mn>1</mn> </mrow> </semantics></math>, <math display="inline"><semantics> <mrow> <msub> <mover accent="true"> <mi>U</mi> <mo stretchy="false">˜</mo> </mover> <mn>1</mn> </msub> <mo>=</mo> <mn>2</mn> </mrow> </semantics></math> in both figures. The width between any two consecutive barriers is unitary.</p>
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29 pages, 50680 KiB  
Article
Relative Radiometric Correction Method Based on Temperature Normalization for Jilin1-KF02
by Shuai Huang, Song Yang, Yang Bai, Yingshan Sun, Bo Zou, Hongyu Wu, Lei Zhang, Jiangpeng Li and Xiaojie Yang
Remote Sens. 2024, 16(21), 4096; https://doi.org/10.3390/rs16214096 - 2 Nov 2024
Viewed by 630
Abstract
The optical remote sensors carried by the Jilin-1 KF02 series satellites have an imaging resolution better than 0.5 m and a width of 150 km. There are radiometric problems, such as stripe noise, vignetting, and inter-slice chromatic aberration, in their raw images. In [...] Read more.
The optical remote sensors carried by the Jilin-1 KF02 series satellites have an imaging resolution better than 0.5 m and a width of 150 km. There are radiometric problems, such as stripe noise, vignetting, and inter-slice chromatic aberration, in their raw images. In this paper, a relative radiometric correction method based on temperature normalization is proposed for the response characteristics of sensors and the structural characteristics of optical splicing of Jilin-1 KF02 series satellites cameras. Firstly, a model of temperature effect on sensor output is established to correct the variation of sensor response output digital number (DN) caused by temperature variation during imaging process, and the image is normalized to a uniform temperature reference. Then, the horizontal stripe noise of the image is eliminated by using the sensor scan line and dark pixel information, and the vertical stripe noise of the image is eliminated by using the method of on-orbit histogram statistics. Finally, the method of superposition compensation is used to correct the vignetting area at the edge of the image due to the lack of energy information received by the sensor so as to ensure the consistency of the image in color and image quality. The proposed method is verified by Jilin-1 KF02A on-orbit images. Experimental results show that the image response is uniform, the color is consistent, the average Streak Metrics (SM) is better than 0.1%, Root-Mean-Square Deviation of the Mean Line (RA) and Generalized Noise (GN) are better than 2%, Relative Average Spectral Error (RASE) and Relative Average Spectral Error (ERGAS) are greatly improved, which are better than 5% and 13, respectively, and the relative radiation quality is obviously improved after relative radiation correction. Full article
(This article belongs to the Special Issue Optical Remote Sensing Payloads, from Design to Flight Test)
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Figure 1

Figure 1
<p>Temperature drift characteristics of the sensor. (<b>a</b>) DN of the sensor at different temperatures; (<b>b</b>) DN of some pixels at different temperatures.</p>
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<p>Stripe noises in level 0 images of Jilin-1 KF02A. (<b>a</b>) Raw panchromatic image; (<b>b</b>) Raw multispectral image.</p>
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<p>Vignetting and chromatic aberration in a level 0 image of Jilin-1 KF02A.</p>
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<p>Jilin-1 KF02A level 0 images of different ground object scenes. (<b>a</b>) Desert; (<b>b</b>) Vegetation; (<b>c</b>) Coast; (<b>d</b>) City; (<b>e</b>) Mountain; (<b>f</b>) Snow.</p>
Full article ">Figure 4 Cont.
<p>Jilin-1 KF02A level 0 images of different ground object scenes. (<b>a</b>) Desert; (<b>b</b>) Vegetation; (<b>c</b>) Coast; (<b>d</b>) City; (<b>e</b>) Mountain; (<b>f</b>) Snow.</p>
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<p>Workflow of relative radiometric correction method.</p>
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<p>Fitting results of <math display="inline"><semantics> <mrow> <msub> <mrow> <mi>k</mi> </mrow> <mrow> <mi>T</mi> </mrow> </msub> </mrow> </semantics></math> for each pixel. (<b>a</b>) Panchromatic band; (<b>b</b>) Multispectral bands.</p>
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<p>Fitting results of <math display="inline"><semantics> <mrow> <msub> <mrow> <mi>v</mi> </mrow> <mrow> <mi>T</mi> </mrow> </msub> </mrow> </semantics></math> for each pixel. (<b>a</b>) Panchromatic band; (<b>b</b>) Multispectral bands.</p>
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<p>Fitting results of model coefficients for each pixel. (<b>a</b>) Coefficient <math display="inline"><semantics> <mrow> <mi>a</mi> </mrow> </semantics></math>; (<b>b</b>) Coefficient <math display="inline"><semantics> <mrow> <mi>c</mi> </mrow> </semantics></math>; (<b>c</b>) Coefficient <math display="inline"><semantics> <mrow> <mi>b</mi> </mrow> </semantics></math>; (<b>d</b>) Coefficient <math display="inline"><semantics> <mrow> <mi>d</mi> </mrow> </semantics></math>.</p>
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<p>Goodness of fit of the model for each pixel. (<b>a</b>) Goodness of fit of <math display="inline"><semantics> <mrow> <msub> <mrow> <mi>k</mi> </mrow> <mrow> <mi>T</mi> </mrow> </msub> </mrow> </semantics></math>; (<b>b</b>) Goodness of fit of <math display="inline"><semantics> <mrow> <msub> <mrow> <mi>v</mi> </mrow> <mrow> <mi>T</mi> </mrow> </msub> </mrow> </semantics></math>.</p>
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<p>The diagram of the histogram matching method.</p>
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<p>The average DN curves per column of the sensor at different energy levels. (<b>a</b>) DN of odd row pixels; (<b>b</b>) DN of even row pixels.</p>
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<p>The diagram of pixel distribution transformation relationship.</p>
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<p>The diagram of superposition compensation in vignetting imaging region.</p>
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<p>Comparison of correction effects in vignetting area. (<b>a</b>) Raw image; (<b>b</b>) Direct coefficient correction; (<b>c</b>) Superposition correction.</p>
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<p>The calculation results of the raw image. (<b>a</b>) Response energy ratio; (<b>b</b>) Response stability.</p>
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<p>The calculation results of the temperature normalization image. (<b>a</b>) Response energy ratio; (<b>b</b>) Response stability.</p>
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<p>Comparison of correction effects in the vignetting area of vegetation. (<b>a</b>) Direct coefficient correction; (<b>b</b>) Superposition correction.</p>
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<p>Comparison of correction effects in the vignetting area of bare soil. (<b>a</b>) Direct coefficient correction; (<b>b</b>) Superposition correction.</p>
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<p>Comparison of correction effects in the vignetting area of city. (<b>a</b>) Direct coefficient correction; (<b>b</b>) Superposition correction.</p>
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<p>Comparison of correction effects in the vignetting area of desert. (<b>a</b>) Direct coefficient correction; (<b>b</b>) Superposition correction.</p>
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<p>Raw and corrected images of a city. (<b>a</b>) Raw image; (<b>b</b>) Corrected without temperature normalization; (<b>c</b>) Corrected using the proposed method.</p>
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<p>Raw and corrected images of a mountain. (<b>a</b>) Raw image; (<b>b</b>) Corrected without temperature normalization; (<b>c</b>) Corrected using the proposed method.</p>
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<p>Raw and corrected images of a desert. (<b>a</b>) Raw image; (<b>b</b>) Corrected without temperature normalization; (<b>c</b>) Corrected using the proposed method.</p>
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<p>Raw and corrected images of water. (<b>a</b>) Raw image; (<b>b</b>) Corrected without temperature normalization; (<b>c</b>) Corrected using the proposed method.</p>
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<p>Raw and corrected images of vegetation. (<b>a</b>) Raw image; (<b>b</b>) Corrected without temperature normalization; (<b>c</b>) Corrected using the proposed method.</p>
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<p>Comparison of SM calculation results.</p>
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15 pages, 40313 KiB  
Article
Prediction of Thin Shoal Reservoirs Under Reef Controlled by Isochronous Stratigraphic Framework
by Shoucheng Xu, Xiuquan Hu, Zejin Shi, Chao Zhang, Jintao Mao and Boqiang Wang
J. Mar. Sci. Eng. 2024, 12(11), 1974; https://doi.org/10.3390/jmse12111974 - 2 Nov 2024
Viewed by 409
Abstract
Despite the great success in the global exploration and development of reef reservoirs, research on bioclastic shoals under reefs is still in its infancy. Bioclastic shoal reservoirs are very thin, with multiple vertical levels and fast lateral changes, which makes accurate prediction of [...] Read more.
Despite the great success in the global exploration and development of reef reservoirs, research on bioclastic shoals under reefs is still in its infancy. Bioclastic shoal reservoirs are very thin, with multiple vertical levels and fast lateral changes, which makes accurate prediction of the reservoir’s location much tougher. To further implement the reservoir distribution, under the guidance of sequence stratigraphy, the prediction of thin shoals under the control of an isochronous stratigraphic framework was established. Using the combination of spectrum shaping and F-X domain noise suppression techniques and utilizing the signal-to-noise ratio spectrum set as the reference, logging curve as supervision, and well seismic calibration and isochronal amplitude slicing as quality control, the seismic frequency band was extended, and the seismic data resolution and signal-to-noise ratio were improved. After frequency extension, the global optimal seismic automatic interpretation technique was used to construct an isochronal stratigraphic framework model. Through waveform facies-controlled inversion and waveform facies-controlled simulation techniques, the elastic properties of the shoal reservoir were obtained, from which the planar distribution of the reservoir was accurately predicted. The above methods were applied to the prediction of the bioclastic shoal reservoir in the lower submember of the Changxing formation in the Yuanba gas field (China). The plane distribution of bioclastic shoal in the first and second levels was identified, which provides a guideline for the prediction of thin shoal reservoirs. Full article
(This article belongs to the Section Geological Oceanography)
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<p>Structural map of the wider study area of the Yuanba gas field (<b>left</b>, adapted from [<a href="#B26-jmse-12-01974" class="html-bibr">26</a>], with permission) and stratigraphic column map of the study area (<b>right</b>).</p>
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<p>Basic procedures to construct the globally optimized isochronous stratigraphic model (adapted from [<a href="#B34-jmse-12-01974" class="html-bibr">34</a>], with permission from The Leading Edge, 2011). (<b>a</b>) Gridded points are linked via a correlation image of neighboring traces. (<b>b</b>) Every point corresponds to a link between a point on X1 and a point on X2 (<b>c</b>). A set of high probability links (A correlation comb) is used to calculate the global position of each point on the sampled grid. (<b>d</b>). The model is constrained by potential seismic signals to ensure consistency.</p>
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<p>Seismic profile of cross Y1–Y2 wells before (<b>upper</b>) and after (<b>lower</b>) frequency extension. (The red arrow shows the change of seismic data before and after frequency extension).</p>
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<p>Amplitude attribute iso-T<sub>0</sub> slice (3084 ms) before (<b>left</b>) and after (<b>right</b>) frequency extension. (Red represents the peaks of the seismic waveform, black represents the troughs of the seismic waveform).</p>
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<p>Y2 well seismic calibration before and after frequency extension (The red dotted line frame reflects the location of reservoir development in Changxing Formation).</p>
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<p>Typical seismic profile and its globally optimized isochronal interpretation model of the studied area. (<b>a</b>) Typical seismic section. (<b>b</b>) Globally optimized isochronous stratigraphic model.</p>
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<p>Isochronous stratigraphic framework in the studied area. (<b>a</b>) Y2 sequence analysis histogram. (<b>b</b>) across Y2 stratigraphic model. (<b>c</b>) Cross-Y2 stratigraphic framework.</p>
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<p>Cross-well profile of facies-controlled high-resolution inversion. (<b>a</b>) Waveform facies-controlled inversion. (<b>b</b>) Constrained sparse spoke inversion. (<b>c</b>) Facies-controlled characteristic curve simulation (The arrows in the figure all point to the location of the Changxing Formation bioclastic shoal).</p>
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<p>Lithology statistics of shoal reservoirs in the Changxing formation of Yuanba. (<b>a</b>) Thickness of reservoirs; (<b>b</b>) gamma against wave impedance; (<b>c</b>) histogram of wave impedance.</p>
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<p>Plan of reservoir prediction of the multi-level shoals of the Changxing formation. (<b>a</b>) First-level shoal reservoir. (<b>b</b>) Second-level shoal reservoir.</p>
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22 pages, 1116 KiB  
Article
Optimizing Open Radio Access Network Systems with LLAMA V2 for Enhanced Mobile Broadband, Ultra-Reliable Low-Latency Communications, and Massive Machine-Type Communications: A Framework for Efficient Network Slicing and Real-Time Resource Allocation
by H. Ahmed Tahir, Walaa Alayed, Waqar ul Hassan and Thuan Dinh Do
Sensors 2024, 24(21), 7009; https://doi.org/10.3390/s24217009 - 31 Oct 2024
Viewed by 589
Abstract
This study presents an advanced framework integrating LLAMA_V2, a large language model, into Open Radio Access Network (O-RAN) systems. The focus is on efficient network slicing for various services. Sensors in IoT devices generate continuous data streams, enabling resource allocation through O-RAN’s dynamic [...] Read more.
This study presents an advanced framework integrating LLAMA_V2, a large language model, into Open Radio Access Network (O-RAN) systems. The focus is on efficient network slicing for various services. Sensors in IoT devices generate continuous data streams, enabling resource allocation through O-RAN’s dynamic slicing and LLAMA_V2’s optimization. LLAMA_V2 was selected for its superior ability to capture complex network dynamics, surpassing traditional AI/ML models. The proposed method combines sophisticated mathematical models with optimization and interfacing techniques to address challenges in resource allocation and slicing. LLAMA_V2 enhances decision making by offering explanations for policy decisions within the O-RAN framework and forecasting future network conditions using a lightweight LSTM model. It outperforms baseline models in key metrics such as latency reduction, throughput improvement, and packet loss mitigation, making it a significant solution for 5G network applications in advanced industries. Full article
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<p>O-RAN big picture architecture and the point where the proposed framework will be deployed [<a href="#B2-sensors-24-07009" class="html-bibr">2</a>].</p>
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<p>End-to-end proposed concept.</p>
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<p>Proposed methodology.</p>
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<p>Latency reduction as a function of increasing power for eMBB, URLLC, and mMTC services in 5G networks.</p>
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<p>Throughput is increased with rising power for eMBB, URLLC, and mMTC services in 5G networks.</p>
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<p>Packet loss decreases with increasing power for eMBB, URLLC, and mMTC services in 5G networks.</p>
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<p>Comparison of decision accuracy between LLAMA V2 and baseline over iterations.</p>
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<p>Comparison of policy explainability scores between LLAMA V2 and baseline over iterations.</p>
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<p>Pareto efficiency of LLAMA V2 compared to baseline over iterations.</p>
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<p>Comparison of the prediction accuracy of LLAMA V2 against a baseline model over multiple iterations for improved performance assessment.</p>
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<p>Comprehensive comparison of the error rates between LLAMA V2 and a baseline model across multiple iterations to assess performance improvements and model reliability.</p>
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14 pages, 514 KiB  
Article
Streaming and Elastic Traffic Service in 5G-Sliced Wireless Networks and Mutual Utilization of Guaranteed Resource Units
by Yves Adou, Ekaterina Markova and Yuliya Gaidamaka
Future Internet 2024, 16(11), 397; https://doi.org/10.3390/fi16110397 - 30 Oct 2024
Viewed by 535
Abstract
Researchers of 5G-sliced Wireless Networks are faced with the task of achieving, at the same time, (i) mandatory isolation among network slices and (ii) the effective utilization of resource at Fifth Generation Base Station (gNB). This article proposes the second version of the [...] Read more.
Researchers of 5G-sliced Wireless Networks are faced with the task of achieving, at the same time, (i) mandatory isolation among network slices and (ii) the effective utilization of resource at Fifth Generation Base Station (gNB). This article proposes the second version of the Preemption-based service Prioritization (PP2) scheme that merges the capabilities of the classical Resource Reservation (RR) and Service Prioritization (SP) schemes and realizes the coexistence of non-TCP streaming and TCP elastic traffic at gNB. Analytical methods are given for Dynamic Resource Sharing (DRS) and Dynamic Resource Reallocation (DRR) with data rate reduction and service preemption. As main results, under some baseline scenario, the PP2 scheme, in comparison with RR, does increase the admission probability up to 99.999% at the system while ensuring 100% in system capacity utilization. Full article
(This article belongs to the Special Issue Performance and QoS Issues of 5G Wireless Networks and Beyond)
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<p><span class="html-italic">K</span>-dimensional QS with customer blocking and service preemption.</p>
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<p>Explanations for Definition 1 (Dynamic Resource Sharing (DRS)). (<b>a</b>) Details about Equation (7); (<b>b</b>) Details about Equation (8); (<b>c</b>) Details about Equation (9).</p>
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<p>Formalization of the rac scheme for accessing a slice <math display="inline"><semantics> <mrow> <mi>k</mi> <mo>∈</mo> <mi mathvariant="script">K</mi> </mrow> </semantics></math> in the system.</p>
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<p>Explanations for Definition 2 (Dynamic Resource Reallocation (DRR)). (<b>a</b>) Details about Equations (10) and (11); (<b>b</b>) Details about Equation (12).</p>
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<p>State transition diagram between <math display="inline"><semantics> <mrow> <mi mathvariant="bold">n</mi> <mo>∈</mo> <mi mathvariant="script">S</mi> </mrow> </semantics></math> and its neighbors <math display="inline"><semantics> <mrow> <mi mathvariant="bold">n</mi> <mo>±</mo> <msub> <mi mathvariant="bold">e</mi> <mi>k</mi> </msub> <mo>,</mo> <mi mathvariant="bold">n</mi> <mo>±</mo> <msub> <mi mathvariant="bold">e</mi> <mi>k</mi> </msub> <mo>±</mo> <msub> <mi mathvariant="bold">m</mi> <mi>k</mi> </msub> <mfenced open="(" close=")"> <mi mathvariant="bold">n</mi> </mfenced> </mrow> </semantics></math>.</p>
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<p>The numerical results of a case example of three slices in a system (<math display="inline"><semantics> <mrow> <mi>K</mi> <mo>=</mo> <mn>3</mn> </mrow> </semantics></math>) for the mean number of customers vs. the offered load. (<b>a</b>) The mean number of customers in non-TCP streaming slice 1; (<b>b</b>) The mean number of customers in non-TCP streaming slice 2; (<b>c</b>) The mean number of customers in TCP elastic slice 3; (<b>d</b>) The mean number of customers in the system.</p>
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<p>The numerical results of a case example of three slices in a system (<math display="inline"><semantics> <mrow> <mi>K</mi> <mo>=</mo> <mn>3</mn> </mrow> </semantics></math>) for the admission probability of customers vs. the offered load. (<b>a</b>) The admission probability of customers at non-TCP streaming slice 1; (<b>b</b>) The admission probability of customers at non-TCP streaming slice 2; (<b>c</b>) The admission probability of customers at TCP elastic slice 3; (<b>d</b>) The admission probability of customers at the system.</p>
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<p>The numerical results of a case example of three slices in a system (<math display="inline"><semantics> <mrow> <mi>K</mi> <mo>=</mo> <mn>3</mn> </mrow> </semantics></math>) for the capacity utilization vs. the offered load. (<b>a</b>) The guaranteed capacity utilization in non-TCP streaming slice 1; (<b>b</b>) The guaranteed capacity utilization in non-TCP streaming slice 2; (<b>c</b>) The guaranteed capacity utilization in TCP elastic slice 3; (<b>d</b>) The minimum data rate utilization in TCP elastic slice 3; (<b>e</b>) The total system capacity utilization.</p>
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