Search Results (559)

This study aimed to analyze the intra-device agreement of a new linear position transducer (Vitruve, VT) and the inter-device agreement with a previously validated linear velocity transducer (T-Force System, TF) in different range of velocities. A group of 50 healthy, physically active men performed a progressive loading test during a bench press (BP) and full-squat (SQ) exercise with a simultaneous recording of two VT and one TF devices. The mean propulsive velocity (MPV) and peak of velocity (PV) were recorded for subsequent analysis. A set of statistics was used to determine the degree of agreement (Intraclass correlation coefficient [ICC], Lin’s concordance correlation coefficient [CCC], mean square deviation [MSD], and variance of the difference between measurements [VMD]) and the error magnitude (standard error of measurement [SEM], smallest detectable change [SDC], and maximum errors [ME]) between devices. The established velocity ranges were as follows: >1.20 m·s⁻¹; 1.20–0.95 m·s⁻¹; 0.95–0.70 m·s⁻¹; 0.70–0.45 m·s⁻¹; ≤0.45 m·s⁻¹ for BP; and >1.50 m·s⁻¹; 1.50–1.25 m·s⁻¹; 1.25–1.00 m·s⁻¹; 1.00–0.75 m·s⁻¹; and ≤0.75 m·s⁻¹ for SQ. For the MPV, the VT system showed high intra- and inter-device agreement and moderate error magnitude with pooled data in both exercises. However, the level of agreement decreased (ICC: 0.790–0.996; CCC: 0.663–0.992) and the error increased (ME: 2.8–13.4% 1RM; SEM: 0.035–0.01 m·s⁻¹) as the velocity range increased. For the PV, the magnitude of error was very high in both exercises. In conclusion, our results suggest that the VT system should only be used at MPVs below 0.45 m·s⁻¹ for BP and 0.75 m·s⁻¹ for SQ in order to obtain an accurate and reliable measurement, preferably using the MPV variable instead of the PV. Therefore, it appears that the VT system may not be appropriate for objectively monitoring resistance training and assessing strength performance along the entire spectrum of load-velocity curve. Full article

The evaluation of ecological environment quality (EEQ) is an important method to measure the quality of ecosystem services. Therefore, the EEQ of Changting County, located in the red soil region of southern China, was assessed by using the remote sensing ecological index (RSEI) based on Landsat images from 1995 to 2019, and its spatiotemporal variability was identified by using the Global Moran’s I index, standard deviational ellipse, and kernel density estimation. The results showed that, firstly, the EEQ degraded from 1995 to 2000, then improved from 2000 to 2019; secondly, the spatial distribution of the RSEI for each study year was not random and had a strong positive correlation; thirdly, the directional distributions of the RSEI for all the grades were almost in the direction of southwest to northeast, and the spatial discrete characteristics of the moderate- and good-grade areas were almost consistent from 1995 to 2019; fourthly, the kernel density distribution of the moderate- and good-grade EEQ was located in towns within the Tingjiang River Basin and in the surroundings of the study area, respectively. This study can help managers to better understand the spatial–temporal variations in the EEQ in the study area, supporting the government in formulating a better ecological restoration strategy. Full article

Despite existing research on child undernutrition in the tropics, a comprehensive understanding of how weather patterns impact childhood growth remains limited. This study summarizes and estimates the effect of rainfall and temperature patterns on childhood linear growth among under-fives in the tropics. A total of 41 out of 829 studies were considered based on preset inclusion criteria. Standardized regression coefficients (β) were used to estimate effect sizes, which were subsequently pooled, and forest plots were generated to visually represent the effect size estimates along with their 95% confidence intervals. Of the total reports, 28 and 13 research articles were included in the narrative synthesis and meta-analysis, respectively. The studies establish that patterns in rainfall and temperature either increase or decrease childhood linear growth and the risk of stunting. An increase in every one standard deviation of rainfall results in a 0.049 standard deviation increase in linear growth (β = 0.049, 95% CI: 0.024 to 0.073). This positive association is likely mediated by various factors. In countries where agriculture is heavily dependent on rainfall, increased precipitation can lead to higher crop yields which could in turn result in improved food security. The improved food security positively impacts childhood nutrition and growth. However, the extent to which these benefits are realized can vary depending on moderating factors such as location and socio-economic status. Temperature pattern showed a negative correlation with linear growth, where each standard deviation increase resulted in a decrease in linear growth by 0.039 standard deviations, with specific impacts varying by regional climates (β = −0.039, 95% CI: −0.065 to −0.013). Additionally, our meta-analysis shows a small but positive relationship of childhood stunting with temperature pattern in western Africa (β = 0.064, 95% CI: 0.035, 0.093). This association is likely due to temperature patterns’ indirect effects on food security and increased disease burden. Thus, the intricate interaction between weather patterns and childhood linear growth requires further research to distinguish the relationship considering other factors in the global tropics. While our findings provide valuable insights, they are primarily based on observational studies from sub-Saharan Africa and may not be generalizable to other tropical regions. Full article

This study aimed to evaluate the biomechanical compatibility of a modular hemipelvic prosthesis by comparing stress distributions between an implanted pelvis and a healthy pelvis. Finite element analysis was used to simulate bilateral standing loads on both models, analyzing critical regions such as the sacroiliac joints, iliac crest, acetabulum, and prosthesis connection points. Six models with varied displacements of the hip joint rotational center were also introduced to assess the impact of deviations on stress distribution. The implanted pelvis had a stress distribution closely matching that of the intact pelvis, indicating that the prosthesis design maintained the biomechanical integrity of the pelvis. Stress patterns in displacement models with deviations of less than 10 mm were similar to the standard model, with only minor changes in stress magnitude. However, backward, upward, and inward deviations resulted in stress concentrations, particularly in the prosthesis connection points, increasing the likelihood of mechanical failure. The modular hemipelvic prosthesis demonstrated good biomechanical compatibility with minimal impact on pelvic stress distribution, even with moderate deviations in the hip joint’s rotational center; outward, forward, and downward displacements are preferable to minimize stress concentration and prevent implant failure in cases where minor deviations in the rotational center are unavoidable during surgery. Full article

Globally, waterborne viral infections significantly threaten public health. While current European Union regulations stipulate that drinking water must be devoid of harmful pathogens, they do not specifically address the presence of enteric viruses in water used for irrigation or food production. Traditional virus detection methods rely on molecular biology assays, requiring specialized personnel and laboratory facilities. Here, we describe an electrochemical sandwich enzyme-linked immunomagnetic assay (ELIME) for the detection of the hepatitis A virus (HAV) in water matrices. This method employed screen-printed electrodes as the sensing platform and utilized commercially available pre-activated magnetic beads to provide a robust foundation for the immunological reaction. The ELIME assay demonstrated exceptional analytical performance in only 185 min achieving a detection limit of 0.5 genomic copies per milliliter (g.c./mL) and exhibiting good reproducibility with a relative standard deviation (RSD) of 7% in HAV-spiked drinking and processing water samples. Compared with the real-time RT-qPCR method described in ISO 15216-1, the ELIME assay demonstrated higher sensitivity, although the overall linearity of the method was moderate. These analytical attributes highlight the potential of the ELIME assay as a rapid and viable alternative for HAV detection in water used for agriculture and food processing. Full article

With the increasing focus on irrigation management, it is crucial to consider cost-effective alternatives for soil water monitoring, such as multi-point monitoring with low-cost soil moisture sensors. This study assesses the accuracy and functionality of low-cost sensors in a sandy loam (SL) soil amended with biochar at rates of 15.6 and 31.2 tons/ha by calibrating the sensors in the presence of two nitrogen (N) and potassium (K) commercial fertilizers at three salinity levels (non/slightly/moderately) and six soil water contents. Sensors were calibrated across nine SL-soil combinations with biochar and N and K fertilizers, counting for 21 treatments. The best fit for soil water content calibration was obtained using polynomial equations, demonstrating reliability with $R^2$ values greater than 0.98 for each case. After a second calibration, low-cost soil moisture sensors provide acceptable results concerning previous calibration, especially for non- and slightly saline treatments and at soil moisture levels lower than 0.17 cm³cm⁻³. The results showed that at low frequencies, biochar and salinity increase the capacitance detected by the sensors, with calibration curves deviating up to 30% from the control sandy loam soil. Due to changes in the physical and chemical properties of soil resulting from biochar amendments and the conductive properties influenced by fertilization practices, it is required to conduct specific and continuous calibrations of soil water content sensor, leading to better agricultural management decisions. Full article

Zirconium hydride is commonly used for next-generation reactor designs due to its excellent hydrogen retention capacity at temperatures below 1000 K. These types of reactors operate at thermal neutron energies and require accurate representation of thermal scattering laws (TSLs) to optimize moderator performance and evaluate the safety indicators for reactor design. In this work, we present an atomic-scale representation of sub-stoichiometric ZrH_2−x$(0.3\le x\le 0.6)$, which relies on ab initio molecular dynamics (AIMD) in tandem with velocity auto-correlation (VAC) analysis to generate phonon density of states (DOS) for TSL development. The novel NJOY+NCrystal tool, developed by the European Spallation Source community, was utilized to generate the TSL formulations in the A Compact ENDF (ACE) format for its utility in neutron transport software. First, stoichiometric zirconium hydride cross sections were benchmarked with experiments. Then sub-stoichiometric zirconium hydride TSLs were developed. Significant deviations were observed between the new $\delta$-phase ZrH_2−x TSLs and the TSLs in the current ENDF release. It was also observed that varying the hydrogen vacancy defect concentration and sites did not cause as significant a change in the TSLs (e.g., ZrH_1.4 vs. ZrH_1.7) as was caused by the lattice transformation from $ϵ$- to $\delta$-phase. Full article

Purpose: Investigate the oxylipin profiles in the aqueous humor of primary open-angle glaucoma (POAG) patients. Methods: Aqueous humor samples were collected from 17 POAG patients and 15 cataract subjects and subjected to a liquid chromatography/mass spectrometry (LC-MS) analysis to detect the oxylipins. The prediction potential of the differential abundant oxylipins was assessed by the receiver operating characteristic (ROC) curves. Pathway and correlation analyses on the oxylipins and clinical and biochemical parameters were also conducted. Results: The LC-MS analysis detected a total of 76 oxylipins, of which 29 oxylipins reached the detection limit. The multivariate analysis identified five differential abundant oxylipins, 15-keto-prostaglandin F2 alpha (15-kPGF2α), Leukotriene B4 (LTB4), 12,13-Epoxyoctadecenoic acid (12,13-Epome), 15-Hydroxyeicosatetraenoic acid (15-HETE) and 11-Hydroxyeicosatetraenoic acid (11-HETE). The five oxylipins are enriched in the arachidonic acid metabolism and linoleic acid metabolism pathways. Pearson correlation analysis showed that 11-HETE was positively correlated with intraocular pressure and central corneal thickness and negatively with cup/disk area ratio in the POAG patients. In addition, 15-kPGF2α was moderately and positively correlated with the mean deviation (MD) of visual field defect, and LTB4 was moderately and negatively correlated with macular thickness. Conclusions: This study revealed the oxylipin profile in the aqueous humor of POAG patients. Oxylipins involved in the arachidonic acid metabolism pathway could play a role in POAG, and anti-inflammatory therapies could be potential treatment strategies for POAG. Full article

Variational data assimilation theoretically assumes Gaussian-distributed observational errors, yet actual data often deviate from this assumption. Traditional quality control methods have limitations when dealing with nonlinear and non-Gaussian-distributed data. To address this issue, our study innovatively applies two advanced machine learning (ML)-based quality control (QC) methods, Minimum Covariance Determinant (MCD) and Isolation Forest, to process precipitable water (PW) data derived from satellite FengYun-2E (FY2E). We assimilated the ML QC-processed TPW data using the Gridpoint Statistical Interpolation (GSI) system and evaluated its impact on heavy precipitation forecasts with the Weather Research and Forecasting (WRF) v4.2 model. Both methods notably enhanced data quality, leading to more Gaussian-like distributions and marked improvements in the model’s simulation of precipitation intensity, spatial distribution, and large-scale circulation structures. During key precipitation phases, the Fraction Skill Score (FSS) for moderate to heavy rainfall generally increased to above 0.4. Quantitative analysis showed that both methods substantially reduced Root Mean Square Error (RMSE) and bias in precipitation forecasting, with the MCD method achieving RMSE reductions of up to 58% in early forecast hours. Notably, the MCD method improved forecasts of heavy and extremely heavy rainfall, whereas the Isolation Forest method demonstrated a superior performance in predicting moderate to heavy rainfall intensities. This research not only provides a basis for method selection in forecasting various precipitation intensities but also offers an innovative solution for enhancing the accuracy of extreme weather event predictions. Full article

Children with obstructive sleep apnea (OSA) frequently experience chronic low-grade systemic inflammation, with the inflammasome playing a central role in OSA. This cross-sectional study evaluated the relationship between weight status, autonomic function, and systemic inflammation in a cohort of 55 children with OSA, predominantly boys (78%) with an average age of 7.4 ± 2.2 years and an apnea-hypopnea index of 14.12 ± 17.05 events/hour. Measurements were taken of body mass index (BMI), sleep heart-rate variability, morning circulatory levels of interleukin-1β, interleukin-1 receptor antagonist, and interleukin-6, and tumor necrosis factor-α, anthropometry, and polysomnography. Multiple linear regression modeling showed that an apnea-hypopnea index was significantly associated with BMI, the standard deviation of successive differences between normal-to-normal intervals during N3 sleep, and the proportion of normal-to-normal interval pairs differing by more than 50 ms during rapid-eye-movement sleep. A moderated mediation model revealed that interleukin-1 receptor antagonist levels mediated the association between BMI and interleukin-6 levels, with sympathovagal balance during N3 sleep and minimum blood oxygen saturation further moderating these relationships. This study highlights the complex relationships between BMI, polysomnographic parameters, sleep heart-rate-variability metrics, and inflammatory markers in children with OSA, underlining the importance of weight management in this context. Full article

To explore the impact of government fiscal intervention on regional carbon emissions, this paper employs a two-way fixed-effects model to analyze data from 30 provinces in China, spanning the period from 2008 to 2017. This study investigates the effects of local government environmental expenditure and government budget on the per capita volume, intensity, and performance of regional carbon emissions. The results show that government environmental expenditure is beneficial to reducing regional carbon emissions and improving regional carbon emission performance. Second, the smaller the deviation between the government budget and final accounts, the more conducive it is to reducing carbon emissions. Third, we found that government environmental expenditure has the strongest inhibitory effect on regional carbon emissions in the eastern region, followed by the central region, and the weakest in the western region. Finally, government financial transparency positively moderates the inhibitory effect of government budget management on regional carbon emissions, that is, when fiscal transparency is high, the amplification effect of budget deviation on regional carbon emissions is weakened. Full article

(1) Background: Chronic hyperglycaemia is a cause of vascular damage and other adverse clinical outcomes in type 2 diabetes mellitus (T2DM). Emerging evidence suggests a significant and independent role for glycaemic variability (GV) in contributing to those outcomes. Continuous glucose monitoring (CGM) provides valuable insights into GV. Unlike in type 1 diabetes mellitus, the use of CGM-derived GV indices has not been widely adopted in the management of T2DM due to the limited evidence of their effectiveness in predicting clinical outcomes. This study aimed to explore the associations between GV metrics and short- or long-term vascular and clinical complications in T2DM. (2) Methods: A rapid literature review was conducted using the Cochrane Library, MEDLINE, and Scopus databases to seek high-level evidence. Lower-quality studies such as cross-sectional studies were excluded, but their content was reviewed. (3) Results: Six studies (five prospective cohort studies and one clinical trial) reported associations between GV indices (coefficient of variation (CV), standard deviation (SD), Mean Amplitude of Glycaemic Excursions (MAGE), Time in Range (TIR), Time Above Range (TAR), and Time Below Range (TBR)), and clinical complications. However, since most evidence came from moderate to low-quality studies, the results should be interpreted with caution. (4) Conclusions: Limited but significant evidence suggests that GV indices may predict clinical compilations in T2DM both in the short term and long term. There is a need for longitudinal studies in larger and more diverse populations, longer follow-ups, and the use of numerous CGM-derived GV indices while collecting information about all microvascular and macrovascular complications. Full article

Background/Objectives: Magnetic resonance imaging (MRI) is the preferred diagnostic means to visualize spinal pathologies, and offers the possibility of precise structural tissue analysis. However, knowledge about MRI-based measurements of physiological cross-sectional musculoskeletal dimensions and associated tissue-specific average structural brightness in the lumbar spine of healthy young women and men is scarce. The current study was planned to investigate characteristic intersexual differences and to provide MRI-related musculoskeletal baseline values before the onset of biological aging. Methods: At a single medical center, lumbar MRI scans of 40 women and 40 men aged 20–40 years who presented with moderate nonspecific low back pain were retrospectively evaluated for sex-specific differences in cross-sectional sizes of the fifth lumbar vertebrae, psoas and posterior paravertebral muscles, and respective sex- and age-dependent average brightness alterations on T2-weighted axial sections in the L5-level. Results: In women (mean age 33.5 years ± 5.0 (standard deviation)), the investigated musculoskeletal cross-sectional area sizes were significantly smaller (p < 0.001) compared to those in men (mean age 33.0 years ± 5.7). Respective average musculoskeletal brightness values were higher in women compared to those in men, and most pronounced in posterior paravertebral muscles (p < 0.001). By correlating brightness results to those of subcutaneous fat tissue, all intersexual differences, including those between fifth lumbar vertebrae and psoas muscles, turned out to be statistically significant. This phenomenon was least pronounced in psoas muscles. Conclusions: Lumbar musculoskeletal parameters showed significantly larger dimensions of investigated anatomical structures in men compared to those in women aged 20–40 years, and an earlier onset and faster progress of bone loss and muscle degradation in women. Full article

Curculio davidi is a major pest in chestnut-producing regions in China, and there have been many studies on its occurrence, biological characteristics, and management strategies. However, few of them have focused on the distribution changes of the pest under climate change. In this study, the MaxEnt model (version 3.3.4) and ArcGIS software (version 10.8) were first employed to map the current and future (2050 s and 2080 s) suitable habitat distribution of the weevil under climate change (CMIP 6: SSP1-2.6, SSP2-4.5, and SSP5-8.5). The results indicate that the highly suitable areas for C. davidi are mainly concentrated in Hubei, Henan, Anhui, Jiangxi, Jiangsu, Zhejiang, the coastal areas of Shandong, and eastern Guizhou, northwestern Hunan, and northeastern Sichuan provinces in China. Through the Jackknife test of 19 climate factors, six climate factors affecting the distribution of C. davidi were identified, with precipitation from July (Prec7), precipitation of warmest quarter (Bio18), and temperature seasonality (standard deviation × 100) (Bio4) contributing a combined percentage of 86.3%. Under three different climate scenarios (CMIP 6: SSP1-2.6, SSP2-4.5, and SSP5-8.5), the area of moderately suitable regions is projected to increase by 22.12–27.33% in the 2050 s and by 17.80–38.22% in the 2080 s compared to the current distribution, while the area of highly suitable regions shows a shrinking trend. This study provides data support for the management strategies of C. davidi and offers new insights into the dynamic changes of similar forestry pests. Full article

Almost every year, earthquakes threaten many lives, so not only do developing countries suffer negative effects from earthquakes on their economies but also developed ones that lose significant economic resources, suffer massive fatalities, and have to suspend businesses and occupancy. Existing buildings in earthquake-prone areas need structural safety assessments or seismic vulnerability assessments. It is crucial to assess earthquake damage before an earthquake to prevent further losses, and to assess building damage after an earthquake to aid emergency responders. Many models do not take into account the surveyor’s subjectivity, which causes observational vagueness and uncertainty. Additionally, a lack of experience or knowledge, engineering errors, and inconspicuous parameters could affect the assessment. Thus, a consensus-based Likert–LMBP (the Levenberg–Marquardt backpropagation algorithm) model was developed to rapidly assess the seismic performance of buildings based on post-earthquake visual images in the devastating Kahramanmaraş earthquake, which occurred on 6 February 2023 and had magnitudes of 7.7 and 7.6 and severely affected 11 districts in Türkiye. Vulnerability variables for buildings are assessed using linguistic variables on a five-point Likert scale based on expert consensus values derived from post-earthquake visual images. The building vulnerability parameters required for the proposed model are determined as the top hill–slope effect, weak story effect, soft story effect, short column effect, plan irregularity, pounding effect, heavy overhang effect, number of stories, construction year, structural system state, and apparent building quality. Structural analyses categorized buildings as no damage, slight damage, moderate damage, or severe damage/collapse. Training the model resulted in quite good performance (mse = 7.26306 × 10⁻⁵). Based on the statistical analysis of the entire data set, the mean and the standard deviation of the errors were 0.00068 and 0.00852, respectively. Full article