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Search Results (6,378)

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Keywords = motion analysis

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16 pages, 4567 KiB  
Article
Reliability of Spino-Pelvic and Sagittal Balance Parameters Assessed During Walking in Patients with Back Pain
by Armand Dominik Škapin, Janez Vodičar, Nina Verdel, Matej Supej and Miha Vodičar
Sensors 2025, 25(6), 1647; https://doi.org/10.3390/s25061647 (registering DOI) - 7 Mar 2025
Abstract
This study aimed to establish and assess the reliability of spino-pelvic and sagittal balance parameters measured during walking in patients with back pain, some of whom had radiological signs of sagittal imbalance, reflecting real-world clinical conditions. Dynamic assessment offers an alternative to conventional [...] Read more.
This study aimed to establish and assess the reliability of spino-pelvic and sagittal balance parameters measured during walking in patients with back pain, some of whom had radiological signs of sagittal imbalance, reflecting real-world clinical conditions. Dynamic assessment offers an alternative to conventional static measurements, potentially improving the evaluation of sagittal balance. Ten patients aged 56–73 years completed a six-minute walking assessment while being monitored by the optoelectric Qualisys Motion Capture System. Forty-nine reflective markers were placed to measure the spino-pelvic and sagittal balance parameters across five gait phases: pre-walk, initial-walk, mid-walk, end-walk, and post-walk. Test–retest reliability was evaluated using the intraclass correlation coefficient (ICC). The results showed excellent reliability for thoracic kyphosis angle (ICC = 0.97), C7-L5 sagittal trunk shift (ICC = 0.91), and global tilt angle (ICC = 0.99); good reliability for auditory meatus-hip axis sagittal trunk shift (ICC = 0.85); and moderate reliability for pelvic angle (ICC = 0.57), lumbar lordosis angle (ICC = 0.72), and sagittal trunk angle (ICC = 0.73). Despite minor marker placement inconsistencies and variations in body movement across trials, the findings support the use of this dynamic assessment method in research settings. Its clinical application could also enhance diagnostic accuracy and treatment planning for patients with sagittal balance disorders, allowing for better-tailored therapeutic interventions. Full article
(This article belongs to the Section Biomedical Sensors)
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<p>Placement positions of 49 reflective markers based on the “Qualisys PAF package: Instituti Ortopedici Rizzoli (IOR)”. This standard image from Qualisys illustrates marker placement as defined in the official protocol.</p>
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<p>A 2D schematic representation of the measured parameters.</p>
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<p>Intraclass correlation coefficients (ICC) with 95% confidence intervals for the measured parameters obtained during two consecutive right or left steps (intra-trial comparison) and across two different trials (inter-trial comparison). The red, yellow, green, and purple shaded areas indicate excellent, good, moderate, and poor test–retest reliability, respectively.</p>
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<p>Bland–Altman plots comparing test and retest values for the measured parameters. Intra-trial comparisons (between two consecutive right or left steps) are displayed on the <b>left</b>, while inter-trial comparisons (across two different trials) are shown on the <b>right</b>. The solid line represents the mean difference between the two measurements, and the dashed lines indicate the limits of agreement (mean difference ± 1.96 times the standard deviation).</p>
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17 pages, 1257 KiB  
Article
Enhanced Emotion Recognition Through Dynamic Restrained Adaptive Loss and Extended Multimodal Bottleneck Transformer
by Dang-Khanh Nguyen, Eunchae Lim, Soo-Hyung Kim, Hyung-Jeong Yang and Seungwon Kim
Appl. Sci. 2025, 15(5), 2862; https://doi.org/10.3390/app15052862 - 6 Mar 2025
Abstract
Emotion recognition in video aims to estimate human emotions using acoustic, visual, and linguistic information. This problem is considered multimodal and requires learning different modalities, such as visual, verbal, and vocal cues. Although previous studies have focused on developing sophisticated deep learning models, [...] Read more.
Emotion recognition in video aims to estimate human emotions using acoustic, visual, and linguistic information. This problem is considered multimodal and requires learning different modalities, such as visual, verbal, and vocal cues. Although previous studies have focused on developing sophisticated deep learning models, this work proposes a different approach using dynamic restrained adaptive loss inspired by multitask learning to understand multimodal inputs jointly. This training strategy allows predictions from one modality to enhance the accuracy of predictions from other modalities, mirroring the concept of multitask learning, where the results of one task can improve the performance of related tasks. Furthermore, this work introduces the extended multimodal bottleneck transformer, an efficient and effective mid-fusion method designed for problems involving more than two modalities to enhance the performance of emotion recognition systems. The proposed method significantly improves results compared to other end-to-end multimodal fusion techniques on three multimodal benchmarks—Interactive Emotional Dyadic Motion Capture (IEMOCAP), Carnegie Mellon University Multimodal Opinion Sentiment and Emotion Intensity (CMU-MOSEI), and the Chinese Multimodal Sentiment Analysis dataset with independent unimodal annotations (CH-SIMS). Full article
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<p>Proposed multimodal learning framework (<b>a</b>) developed from traditional multimodal learning (<b>b</b>) and inspired by multitask learning (<b>c</b>).</p>
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<p>Block diagram of the proposed framework.</p>
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<p>Illustration of proposed XMBT.</p>
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<p>CMU-MOSEI and IEMOCAP test results for XMBT by training strategy.</p>
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<p>Evaluation metrics of IEMOCAP.</p>
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<p>CMU-MOSEI test results of XMBT and open-ended MBT variants.</p>
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<p>CMU-MOSEI test results of XMBT by temperature and number of bottleneck layers.</p>
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<p>T-SNE visualization of modal-specific representations of IEMOCAP samples using (<b>upper</b>) conventional loss function and (<b>lower</b>) DRA loss function.</p>
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17 pages, 4555 KiB  
Article
Preliminary Study on Wearable Smart Socks with Hydrogel Electrodes for Surface Electromyography-Based Muscle Activity Assessment
by Gabriele Rescio, Elisa Sciurti, Lucia Giampetruzzi, Anna Maria Carluccio, Luca Francioso and Alessandro Leone
Sensors 2025, 25(5), 1618; https://doi.org/10.3390/s25051618 - 6 Mar 2025
Abstract
Surface electromyography (sEMG) is increasingly important for prevention, diagnosis, and rehabilitation in healthcare. The continuous monitoring of muscle electrical activity enables the detection of abnormal events, but existing sEMG systems often rely on disposable pre-gelled electrodes that can cause skin irritation and require [...] Read more.
Surface electromyography (sEMG) is increasingly important for prevention, diagnosis, and rehabilitation in healthcare. The continuous monitoring of muscle electrical activity enables the detection of abnormal events, but existing sEMG systems often rely on disposable pre-gelled electrodes that can cause skin irritation and require precise placement by trained personnel. Wearable sEMG systems integrating textile electrodes have been proposed to improve usability; however, they often suffer from poor skin–electrode coupling, leading to higher impedance, motion artifacts, and reduced signal quality. To address these limitations, we propose a preliminary model of smart socks, integrating biocompatible hybrid polymer electrodes positioned over the target muscles. Compared with commercial Ag/AgCl electrodes, these hybrid electrodes ensure lower the skin–electrode impedance, enhancing signal acquisition (19.2 ± 3.1 kΩ vs. 27.8 ± 4.5 kΩ for Ag/AgCl electrodes). Moreover, to the best of our knowledge, this is the first wearable system incorporating hydrogel-based electrodes in a sock specifically designed for the analysis of lower limb muscles, which are crucial for evaluating conditions such as sarcopenia, fall risk, and gait anomalies. The system incorporates a lightweight, wireless commercial module for data pre-processing and transmission. sEMG signals from the Gastrocnemius and Tibialis muscles were analyzed, demonstrating a strong correlation (R = 0.87) between signals acquired with the smart socks and those obtained using commercial Ag/AgCl electrodes. Future studies will further validate its long-term performance under real-world conditions and with a larger dataset. Full article
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<p>Overview of the hardware architecture.</p>
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<p>Overview of the socks. (<b>a</b>) External side of the socks: equipped with a pocket for the electronic device and the cables that connect the electronic device to the electrodes. (<b>b</b>) Internal side of the socks: equipped with five pockets for placing the TA, GL, and reference electrodes. (<b>c</b>) User wearing sock: correct placement of electrodes enables the measurement of the EMG signal from selected muscles.</p>
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<p>Acquisition protocol. Each volunteer performed the activities shown in the figure for the time indicated, where GL MVC and TA MVC are defined as the maximum voluntary contraction of the Gastrocnemius muscle and Tibialis muscle, respectively.</p>
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<p>(<b>a</b>) Schematic representation of hybrid polymer electrode (HPe) production. (<b>b</b>) Photographs of fabricated HP electrodes and their connection to a commercial snap-on cable.</p>
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<p>(<b>a</b>) LED test with HP hydrogel electrode; (<b>b</b>) impedance versus potential of HP hydrogel electrodes and commercial hydrogel electrodes; (<b>c</b>) impedance versus frequency of HP electrodes and commercial electrodes; (<b>d</b>) Nyquist plot and equivalent circuit model used for fitting. Dashed lines represent measured experimental data; solid lines represent the fitted curves.</p>
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<p>(<b>a</b>) Raw and (<b>b</b>) processed signals recorded with the commercial system; (<b>c</b>) raw and (<b>d</b>) processed signals captured using the in-house system; and (<b>e</b>) a comparison of the processed signal, measured using commercial electrodes and in-house-developed stockings during the execution of three repetitions of 5 s of MVC of the Tibialis Anterior muscle followed by 10 s of rest.</p>
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<p>Example of signal patterns captured from the Gastrocnemius and Tibialis muscles during walking and strong muscle contraction using (<b>a</b>) the commercial electrodes and (<b>b</b>) the sock system.</p>
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16 pages, 3299 KiB  
Systematic Review
Comminuted Mason III/IV Radial Head Fractures: What Is the Best Treatment Between Prosthesis and Radial Head Resection? A Systematic Review and Meta-Analysis
by Luca Bianco Prevot, Livio Pietro Tronconi, Vittorio Bolcato, Riccardo Accetta, Stefania Fozzato and Giuseppe Basile
J. Clin. Med. 2025, 14(5), 1773; https://doi.org/10.3390/jcm14051773 - 6 Mar 2025
Abstract
Background/Objectives: Various surgical methods have been proposed for the treatment of comminuted Mason III/IV radial head fractures. In particular, the advantages and disadvantages between prosthesis implantation (RHA) or radial head resection (RHR) are not sufficiently quantified in the current literature. Methods: [...] Read more.
Background/Objectives: Various surgical methods have been proposed for the treatment of comminuted Mason III/IV radial head fractures. In particular, the advantages and disadvantages between prosthesis implantation (RHA) or radial head resection (RHR) are not sufficiently quantified in the current literature. Methods: A systematic literature search was conducted using PubMed Web of Science, Cochrane Library, and Embase in February 2024. Studies conducted on patients with Mason type III or IV radial head fractures and studies relating to surgical methods, including radial head resection or Radial head prosthesis implantation, were included. The two methods were evaluated in terms of clinical and functional results through the DASH score (Disability of the arm, shoulder, and hand), Mayo Elbow Performance Index (MEPI), and flexion-extension range of motion. The onset of osteoarthritis and complications were also assessed. Risk of bias and quality of evidence were assessed using Cochrane guidelines. Results: A total of 345 articles were evaluated and, of these, 21 were included in the study for a total of 552 patients. The results of the meta-analysis showed no significant differences in favor of RHA or RHR in terms of Mayo Elbow Performance (p = 0.58), degrees of flexion (p = 0.689), degrees of extension deficit (p = 0.697), and overall incidence of complications (p = 0.389), while it highlighted a statistically significant difference in terms of DASH score (19.2 vs. 16.2, respectively; p = 0.008) and subjects who developed osteoarthritis (13.4% vs. 47.3%, respectively; p = 0.046). Conclusions: The results of this meta-analysis confirm that both surgical methods provide good functional outcomes, with no significant differences in MEPI, DASH, and range of motion. However, a higher incidence of post-traumatic osteoarthritis was observed in patients undergoing RHR. Additionally, RHR patients exhibited slightly worse functional outcomes in the DASH score; however, this difference is not substantial enough to be considered clinically significant. These findings suggest that while both techniques are viable, RHA may be preferable in patients at higher risk of joint degeneration and instability, and the choice of treatment should be tailored to individual patient characteristics. Full article
(This article belongs to the Special Issue Trends and Prospects in Shoulder and Elbow Surgery)
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<p>Shows the illustrating flowchart of the selection process of the articles.</p>
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<p>Forest plots for MEPS, DASH, and Elbow flexion and extension, CI = confidence interval, MD = mean difference.</p>
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<p>Forest plots for OA and Complications, CI = confidence interval, RR = risk ration.</p>
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<p>Risk of bias assessments according to RoB 2.0 tools.</p>
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<p>Risk of bias assessments according to ROBINS tools.</p>
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17 pages, 3529 KiB  
Article
Meta-Transfer-Learning-Based Multimodal Human Pose Estimation for Lower Limbs
by Guoming Du, Haiqi Zhu, Zhen Ding, Hong Huang, Xiaofeng Bie and Feng Jiang
Sensors 2025, 25(5), 1613; https://doi.org/10.3390/s25051613 - 6 Mar 2025
Abstract
Accurate and reliable human pose estimation (HPE) is essential in interactive systems, particularly for applications requiring personalized adaptation, such as controlling cooperative robots and wearable exoskeletons, especially for healthcare monitoring equipment. However, continuously maintaining diverse datasets and frequently updating models for individual adaptation [...] Read more.
Accurate and reliable human pose estimation (HPE) is essential in interactive systems, particularly for applications requiring personalized adaptation, such as controlling cooperative robots and wearable exoskeletons, especially for healthcare monitoring equipment. However, continuously maintaining diverse datasets and frequently updating models for individual adaptation are both resource intensive and time-consuming. To address these challenges, we propose a meta-transfer learning framework that integrates multimodal inputs, including high-frequency surface electromyography (sEMG), visual-inertial odometry (VIO), and high-precision image data. This framework improves both accuracy and stability through a knowledge fusion strategy, resolving the data alignment issue, ensuring seamless integration of different modalities. To further enhance adaptability, we introduce a training and adaptation framework with few-shot learning, facilitating efficient updating of encoders and decoders for dynamic feature adjustment in real-time applications. Experimental results demonstrate that our framework provides accurate, high-frequency pose estimations, particularly for intra-subject adaptation. Our approach enables efficient adaptation to new individuals with only a few new samples, providing an effective solution for personalized motion analysis with minimal data. Full article
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<p>Sensor placement and data collection environment: (<b>a</b>) For the lower body, six sEMG sensors were placed on both sides of the legs, while 16 Vicon markers were used to collect ground-truth data. An Intel RealSense T265 sensor was mounted on the waist. (<b>b</b>) Ten Vicon cameras were positioned on the ceiling to capture reflective markers on the lower body, and an RGB camera was placed on the side wall. The subject performed walking trials on flat ground, both clockwise and counterclockwise.</p>
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<p>Overall schematic of proposed framework, totally including three phases.</p>
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<p>The pose estimation network is pipelined with feature extraction, knowledge sharing, fusion of knowledge and pose regression.</p>
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<p>The structure of CBAM-Resnet12 is composed of a combination of CBAM module, residual block, convolution layer and max pooling layer.</p>
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<p>Results on different subjects with different scales of pre-training.</p>
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<p>Evaluation of different joints from lower body, results are calculated with RMSE in degrees.</p>
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32 pages, 6211 KiB  
Article
Mechanical Structure Design and Motion Simulation Analysis of a Lower Limb Exoskeleton Rehabilitation Robot Based on Human–Machine Integration
by Chenglong Zhao, Zhen Liu, Yuefa Ou and Liucun Zhu
Sensors 2025, 25(5), 1611; https://doi.org/10.3390/s25051611 - 6 Mar 2025
Viewed by 22
Abstract
Population aging is an inevitable trend in contemporary society, and the application of technologies such as human–machine interaction, assistive healthcare, and robotics in daily service sectors continues to increase. The lower limb exoskeleton rehabilitation robot has great potential in areas such as enhancing [...] Read more.
Population aging is an inevitable trend in contemporary society, and the application of technologies such as human–machine interaction, assistive healthcare, and robotics in daily service sectors continues to increase. The lower limb exoskeleton rehabilitation robot has great potential in areas such as enhancing human physical functions, rehabilitation training, and assisting the elderly and disabled. This paper integrates the structural characteristics of the human lower limb, motion mechanics, and gait features to design a biomimetic exoskeleton structure and proposes a human–machine integrated lower limb exoskeleton rehabilitation robot. Human gait data are collected using the Optitrack optical 3D motion capture system. SolidWorks 3D modeling software Version 2021 is used to create a virtual prototype of the exoskeleton, and kinematic analysis is performed using the standard Denavit–Hartenberg (D-H) parameter method. Kinematic simulations are carried out using the Matlab Robotic Toolbox Version R2018a with the derived D-H parameters. A physical prototype was fabricated and tested to verify the validity of the structural design and gait parameters. A controller based on BP fuzzy neural network PID control is designed to ensure the stability of human walking. By comparing two sets of simulation results, it is shown that the BP fuzzy neural network PID control outperforms the other two control methods in terms of overshoot and settling time. The specific conclusions are as follows: after multiple walking gait tests, the robot’s walking process proved to be relatively safe and stable; when using BP fuzzy neural network PID control, there is no significant oscillation, with an overshoot of 5.5% and a settling time of 0.49 s, but the speed was slow, with a walking speed of approximately 0.18 m/s, a stride length of about 32 cm, and a gait cycle duration of approximately 1.8 s. The model proposed in this paper can effectively assist patients in recovering their ability to walk. However, the lower limb exoskeleton rehabilitation robot still faces challenges, such as a slow speed, large size, and heavy weight, which need to be optimized and improved in future research. Full article
(This article belongs to the Section Sensors and Robotics)
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<p>Schematic diagram of the human gait cycle (R: Right leg; L: Left leg; IC: Initial Contact; FO: Foot Off; MS: Mid-swing).</p>
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<p>Experiment procedure: (<b>a</b>) distribution of muscle groups in human gait; (<b>b</b>) marker placement locations; (<b>c</b>) tracking of the moving target points.</p>
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<p>Gait model.</p>
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<p>Joint angle change curves within the gait cycle: (<b>a</b>) hip joint angle change; (<b>b</b>) knee joint angle change; (<b>c</b>) ankle joint angle change.</p>
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<p>Lower limb exoskeleton rehabilitation robot joint design: (<b>a</b>) hip joint; (<b>b</b>) knee joint; (<b>c</b>) ankle joint; (<b>d</b>) overall 3D structure.</p>
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<p>Lower limb exoskeleton rehabilitation robot joint design: (<b>a</b>) hip joint; (<b>b</b>) knee joint; (<b>c</b>) ankle joint; (<b>d</b>) overall 3D structure.</p>
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<p>Schematic diagram of the kinematic coordinate system configuration for the left leg of the lower limb exoskeleton.</p>
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<p>Three-dimensional model of the left leg.</p>
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<p>Inverse kinematics verification: (<b>a</b>) forward kinematics model; (<b>b</b>) inverse kinematics model.</p>
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<p>Membership function plots: (<b>a</b>) membership function of input variable <span class="html-italic">e</span>; (<b>b</b>) membership function of input variable <span class="html-italic">ec</span>; (<b>c</b>) membership function of output variable <span class="html-italic">k<sub>p</sub></span>; (<b>d</b>) membership function of output variable <span class="html-italic">k<sub>i</sub></span>; (<b>e</b>) membership function of output variable <span class="html-italic">k<sub>d.</sub></span></p>
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<p>Membership function plots: (<b>a</b>) membership function of input variable <span class="html-italic">e</span>; (<b>b</b>) membership function of input variable <span class="html-italic">ec</span>; (<b>c</b>) membership function of output variable <span class="html-italic">k<sub>p</sub></span>; (<b>d</b>) membership function of output variable <span class="html-italic">k<sub>i</sub></span>; (<b>e</b>) membership function of output variable <span class="html-italic">k<sub>d.</sub></span></p>
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<p>Structure of BP neural network.</p>
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<p>Simulink simulation results: (<b>a</b>) no disturbance; (<b>b</b>) with disturbance.</p>
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<p>Prototype donning demonstration.</p>
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<p>EMG amplitude (%MVC): (<b>a</b>) gastrocnemius; (<b>b</b>) biceps femoris; (<b>c</b>) rectus femoris; (<b>d</b>) tibialis anterior.</p>
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<p>EMG amplitude (%MVC): (<b>a</b>) gastrocnemius; (<b>b</b>) biceps femoris; (<b>c</b>) rectus femoris; (<b>d</b>) tibialis anterior.</p>
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<p>Walking gait test.</p>
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17 pages, 2564 KiB  
Article
Comparative Analysis of Amorphous and Biodegradable Copolymers: A Molecular Dynamics Study Using a Multi-Technique Approach
by Alovidin Nazirov, Jacek Klinowski and John Nobleman
Molecules 2025, 30(5), 1175; https://doi.org/10.3390/molecules30051175 - 6 Mar 2025
Viewed by 119
Abstract
We investigate the molecular dynamics of glycolide/lactide/caprolactone (Gly/Lac/Cap) copolymers using differential scanning calorimetry (DSC), Fourier transform infrared spectroscopy (FTIR), 1H second-moment, 1H spin-lattice relaxation time (T1) analysis, and 13C solid-state NMR over a temperature range of 100–413 K. [...] Read more.
We investigate the molecular dynamics of glycolide/lactide/caprolactone (Gly/Lac/Cap) copolymers using differential scanning calorimetry (DSC), Fourier transform infrared spectroscopy (FTIR), 1H second-moment, 1H spin-lattice relaxation time (T1) analysis, and 13C solid-state NMR over a temperature range of 100–413 K. Activation energies and correlation times of the biopolymer chains were determined. At low temperatures, relaxation is governed by the anisotropic threefold reorientation of methyl (-CH3) groups in lactide. A notable change in T1 at ~270 K and 294 K suggests a transition in amorphous phase mobility due to translational diffusion, while a second relaxation minimum (222–312 K) is linked to CH2 group dynamics influenced by caprolactone. The activation energy increases from 5.9 kJ/mol (methyl motion) to 22–33 kJ/mol (segmental motion) as the caprolactone content rises, enhancing the molecular mobility. Conversely, lactide restricts motion by limiting rotational freedom, thereby slowing global dynamics. DSC confirms that increasing ε-caprolactone lowers the glass transition temperature, whereas higher glycolide and lactide content raises it. The onset temperature of main-chain molecular motion varies with the composition, with greater ε-caprolactone content enhancing flexibility. These findings highlight the role of composition in tuning relaxation behavior and molecular mobility in copolymers. Full article
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<p>DSC thermograms of copolymers 0.5Gly/0.2Lac/0.3Cap and 0.5Gly/0.4Lac/0.1Cap, where heating (1⟶) and cooling (⟵2) are indicated. The dashed vertical lines represent a phase transition temperature (T<sub>g</sub>).</p>
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<p>Solution-state <sup>13</sup>C NMR spectra (75 MHz) of copolymers 0.5Gly/0.2Lac/0.3Cap and 0.5Gly/0.4Lac/0.1Cap recorded at 313 K. Letters (A–G) indicate the assignment of molecular groups. The samples were dissolved in CDCl<sub>3</sub> (chloroform-d, 77.2 ppm, triplet due to deuterium coupling), with TMS (0 ppm) as the internal reference.</p>
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<p>Derivatives of <sup>1</sup>H NMR absorption spectra of (<b>a</b>) 0.5Gly/0.2Lac/0.3Cap and (<b>b</b>) 0.5Gly/0.4Lac/0.1Cap at different temperatures. The proton derivative spectra at 273 K are highly sensitive compared to the broad DSC lines (c.f. <a href="#molecules-30-01175-f001" class="html-fig">Figure 1</a>) for both polymers, indicating the early onset of chain molecular dynamics motion in preparation for the phase transition.</p>
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<p>Second moments of the <sup>1</sup>H NMR lines of 0.5Gly/0.2Lac/0.3Cap and 0.5Gly/0.4Lac/0.1Cap versus temperature. The glass phase transition temperatures, T<sub>g</sub> indicated by the vertical lines (according to DSC, c.f. <a href="#molecules-30-01175-f001" class="html-fig">Figure 1</a>).</p>
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<p>Arrhenius plots of <sup>1</sup>H spin-lattice relaxation times measurements at 200 MHz and 9 MHz for 0.5Gly/0.2Lac/0.3Cap and 0.5Gly/0.4Lac/0.1Cap. <sup>1</sup>H experimental data fitted using the BPP model as indicated by solid lines. The experiments conducted from the low to high temperatures and the glass phase transition T<sub>g</sub> indicated by the vertical dashed lines (according to DSC, c.f. <a href="#molecules-30-01175-f001" class="html-fig">Figure 1</a>).</p>
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<p>The resonance frequency of 75.56 MHz <sup>13</sup>C solid-state NMR of copolymers 0.5Gly/0.2Lac/0.3Cap and 0.5Gly/0.4Lac/0.1Cap at different temperatures. The molecular groups are indicated by letters corresponding to the structure of copolymer chains. Solid-state NMR technology is still under development compared to its solution-state counterpart. One of the key technical challenges is the difficulty of spinning amorphous materials at high speeds. Due to their unique behavioral properties, such as superfluid-like elasticity, these materials tend to lose centrifugal axis stability during rotation. The magnitude of <sup>13</sup>C hydrocarbon signals effectively increases with rising temperature, corresponding to an increase in intensity due to fast trans-gauche isomerization and translational diffusion motion.</p>
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<p>FTIR spectra of copolymers (<b>a</b>) 0.5Gly/0.2Lac/0.3Cap and (<b>b</b>) 0.5Gly/0.4Lac/0.1Cap at different temperatures. The band assignments correspond to hydroxyl end-groups (-OH), carbonyl (C=O), methyl (-CH<sub>3</sub>), methylene (-CH<sub>2</sub>-), and methide (-CH-) vibrational motions. The spectra clearly indicate differences in the vibrational motions of the modulated chains.</p>
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25 pages, 2143 KiB  
Article
Assessing the Socioeconomic Impacts of an Inductive Electric Road System (ERS) for Decarbonizing Freight Transport: A Case Study for the TEN-T Corridor AP-7 in Spain
by Rubén Flores-Gandur, José Manuel Vassallo and Natalia Sobrino
Sustainability 2025, 17(5), 2283; https://doi.org/10.3390/su17052283 - 5 Mar 2025
Viewed by 285
Abstract
Electric Road Systems (ERS) are emerging technologies that enable electricity transfer to electric vehicles in motion. However, their implementation presents challenges due to high energy demands and infrastructure requirements. This technology offers a significant opportunity for decarbonizing road freight transport, one of the [...] Read more.
Electric Road Systems (ERS) are emerging technologies that enable electricity transfer to electric vehicles in motion. However, their implementation presents challenges due to high energy demands and infrastructure requirements. This technology offers a significant opportunity for decarbonizing road freight transport, one of the most carbon-intensive sectors, contributing to the European Union’s climate goals. This study hypothesizes that implementing an inductive ERS for freight transport along the AP-7 corridor in Spain will generate environmental benefits—primarily through greenhouse gas (GHG) emission reductions—that outweigh the associated socioeconomic costs, making it a viable decarbonization strategy. To test this hypothesis, an impact assessment framework based on Cost–Benefit Analysis (CBA) is conducted, incorporating climate change and other environmental benefits. The framework is applied to a section of the Mediterranean Highway Corridor AP-7 in Spain. The results indicate that the most significant benefits are derived from positive environmental impacts and lower vehicle operation costs. Through a sensitivity analysis, our research identifies key variables affecting the system’s socioeconomic profitability, including payload capacity, volatility of energy prices and shadow prices of GHG emissions. The study provides insights for policymakers to optimize ERS deployment strategies, ensuring maximum social benefits while addressing economic and environmental challenges. Full article
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<p>Types of technology and configuration of power pick-up and supply [<a href="#B9-sustainability-17-02283" class="html-bibr">9</a>].</p>
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<p>Impact identification and classification.</p>
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<p>Case study location.</p>
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<p>ERS configuration. Source: Own elaboration based on [<a href="#B36-sustainability-17-02283" class="html-bibr">36</a>].</p>
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<p>Tornado graph of NPV of variation for different parameters.</p>
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15 pages, 3958 KiB  
Article
Modeling Movement Stability of Machine-Tractor Units Based on Modular Type Tractor
by Volodymyr Nadykto, Gennadii Golub, Nataliya Tsyvenkova, Volodymyr Kyurchev, Oleksandr Skliar, Radmila Skliar, Victor Golub and Vladyslav Shubenko
Appl. Sci. 2025, 15(5), 2822; https://doi.org/10.3390/app15052822 - 5 Mar 2025
Viewed by 184
Abstract
The object of the present research is a machine-tractor unit based on a tractor consisting of an energy (high-energy tractor—EM) and a technological (additional traction axle—TM) module. This tractor uses three-row crop cultivators, each with an operating width of 4.2 m. One of [...] Read more.
The object of the present research is a machine-tractor unit based on a tractor consisting of an energy (high-energy tractor—EM) and a technological (additional traction axle—TM) module. This tractor uses three-row crop cultivators, each with an operating width of 4.2 m. One of these cultivators is attached centrally to the technological module, and the other two are connected to the sides of the energy module in its front part. The research aimed to determine the influence degree of such a unit scheme and design parameters on the stability of its movement in the horizontal plane. The theoretical analysis was performed using amplitude (AFC) and phase (PFC) frequency characteristics obtained based on the developed mathematical model of the modular unit movement when it processes a disturbing effect. The difference in traction resistances of the unit’s side cultivators was adopted as the latter. Finally, it was established that blocking the vertical hinge of the TM contributes to a significant increase in the unit motion stability. The practical implementation of this method of joining EM and TM in the horizontal plane allows the unit to work out a disturbing influence in the frequency range 0.65–5.50 s−1 to eliminate the resonant AFC peaks and reduce their value. When the TM hinge is locked at a torque oscillation frequency of 2.5 s−1, the AFC is 2.82 times less than when it is free. Blocking the TM vertical hinge increases the delay in the unit’s response to a disturbance. At an oscillation frequency of the latter of 1.5 s−1, this delay is 0.6 s, and at a frequency of 0.5 s−1, it increases by more than three times, reaching a level of 1.9 s. Full article
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<p>Module design tractor.</p>
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<p>Diagram of forces acting on a modular tractor in a horizontal plane.</p>
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<p>MTU’s diagrams based on modular tractor with the components of the main vector of forces (<math display="inline"><semantics> <mrow> <msub> <mrow> <mi>R</mi> </mrow> <mrow> <mi>n</mi> <mi>x</mi> </mrow> </msub> <mo>,</mo> <mo> </mo> <msub> <mrow> <mi>R</mi> </mrow> <mrow> <mi>n</mi> <mi>y</mi> </mrow> </msub> </mrow> </semantics></math>) reduced to the EM mass centre, as well as the central moment of forces <math display="inline"><semantics> <mrow> <msub> <mrow> <mi>M</mi> </mrow> <mrow> <mi>P</mi> </mrow> </msub> </mrow> </semantics></math> acting from: (<b>a</b>) the front and side agricultural machines; (<b>b</b>) the rear and side agricultural machines.</p>
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<p>Sensor placement for <math display="inline"><semantics> <mrow> <mi>α</mi> </mrow> </semantics></math> angle recording.</p>
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<p>Experimental (⸺) and theoretical (- - -) normalized spectral densities of MTU heading angle (D<sub>1</sub> and D<sub>2</sub> are experimental and theoretical heading angle variances, respectively).</p>
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<p>AFC of the dynamic system with unlocked (⸺) and locked (- - -) states of the TM vertical hinge.</p>
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<p>PFC of the dynamic system with unlocked (⸺) and locked (- - -) states of the TM vertical hinge.</p>
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<p>Difference in response delays of a dynamic system to disturbing influence.</p>
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<p>Frequency response of processing the disturbing influence of the unit without TM (⸺) and with it (- - -) when its vertical hinge is locked.</p>
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18 pages, 12446 KiB  
Article
Dynamic Behavior of Carbon Nanotube-Reinforced Polymer Composite Ring-like Structures: Unraveling the Effects of Agglomeration, Porosity, and Elastic Coupling
by Hossein Mottaghi T., Moein A. Ghandehari and Amir R. Masoodi
Polymers 2025, 17(5), 696; https://doi.org/10.3390/polym17050696 - 5 Mar 2025
Viewed by 81
Abstract
This research examines the free vibration characteristics of composite ring-like structures enhanced with carbon nanotubes (CNTs), taking into account the effects of CNT agglomeration. The structural framework comprises two concentric composite rings linked by elastic springs, creating a coupled beam ring (CBR) system. [...] Read more.
This research examines the free vibration characteristics of composite ring-like structures enhanced with carbon nanotubes (CNTs), taking into account the effects of CNT agglomeration. The structural framework comprises two concentric composite rings linked by elastic springs, creating a coupled beam ring (CBR) system. The first-order shear deformation theory (FSDT) is applied to account for transverse shear deformation, while Hamilton’s principle is employed to formulate the governing equations of motion. The effective mechanical properties of the composite material are assessed with regard to CNT agglomeration, which has a significant impact on the elastic modulus and the overall dynamic behavior of the structure. The numerical analysis explores the influence of porosity distribution, boundary conditions (BCs), and the stiffness of the springs on the natural vibration frequencies (NVFs). The results demonstrate that an increase in CNT agglomeration leads to a reduction in the stiffness of the composite, consequently decreasing the NVFs. Furthermore, asymmetric porosity distributions result in nonlinear fluctuations in NVFs due to irregularities in mass and stiffness, whereas uniform porosity distributions display a nearly linear relationship. This study also emphasizes the importance of boundary conditions and elastic coupling in influencing the vibrational response of CBR systems. These findings offer significant insights for the design and optimization of advanced composite ring structures applicable in aerospace, nanotechnology, and high-performance engineering systems. Full article
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<p>The definition of the geometry of the CBR.</p>
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<p>The definition of the geometry of the QCBR.</p>
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<p>The definition of the geometry of the QCBR system.</p>
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<p>A schematic of agglomeration in clusters in a beam section.</p>
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<p>Reduction in the <span class="html-italic">E</span>, <span class="html-italic">G</span>, and <span class="html-italic">K</span> of the composite material with variation <span class="html-italic">V<sub>cnt</sub></span>.</p>
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<p>Equivalent <span class="html-italic">E</span> and <span class="html-italic">ρ</span> functions of the porous material for various initial porosity values.</p>
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<p>Equivalent <span class="html-italic">E</span> and <span class="html-italic">ρ</span> functions of the porous material for various initial porosity values.</p>
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<p>Values of <span class="html-italic">E</span> and <span class="html-italic">ρ</span> for a material for various <span class="html-italic">z</span>.</p>
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<p>NVFs of QCNCR for different porosity distribution patterns with C-C and S-S BCs.</p>
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<p>NVFs for various spring stiffness values under different BCs: (<b>a</b>) C-C/C-C, (<b>b</b>) C-F/C-F, (<b>c</b>) C-S/C-S, (<b>d</b>) S-S/S-S, and (<b>e</b>) SD-SD/SD-SD.</p>
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15 pages, 5870 KiB  
Article
Modelling the Constitutive Behaviour of Recycled PET for the Manufacture of Woven Fabrics
by Huidong Wei, Shan Lou, Martin Leeming and Ying Zhang
Sustainability 2025, 17(5), 2254; https://doi.org/10.3390/su17052254 - 5 Mar 2025
Viewed by 79
Abstract
Recycling polyethylene terephthalate (rPET) from packaging materials consumes a vast amount of energy and incurs significant economic and environmental costs. This study proposes directly recycling rPET into woven fabrics to eliminate reprocessing while still preserving the mechanical performance of the material. The mechanical [...] Read more.
Recycling polyethylene terephthalate (rPET) from packaging materials consumes a vast amount of energy and incurs significant economic and environmental costs. This study proposes directly recycling rPET into woven fabrics to eliminate reprocessing while still preserving the mechanical performance of the material. The mechanical properties of rPET were tested along two orthogonal directions, and the resulting test data were used to calibrate an elasto-plastic model in order to capture the constitutive behaviour of the material. Additionally, the virtual weaving of rPET fibres into fabrics was modelled using finite element analysis (FEA) to replicate the actual manufacturing process. The results show that rPET that is directly recycled into woven fabrics exhibits superior performance to the same material derived from reprocessing. A strong anisotropy of rPET materials was observed, with distinct elastic and ductile behaviours. The FEA simulation also revealed the critical role of the ductility of rPET fibres when used as warp yarns. The process parameters to achieve a successful weaving operation for different yarn configurations, taking into account the motion and tension of the fibres during manufacture, were also identified. A further sensitivity study highlights the influence of friction between the fibres on the tension force of warp yarns. The virtual manufacture-by-weaving model suggests that utilising rPET with a simplified recycling approach can lead to the sustainable manufacture of fabrics with broad industrial applications. Full article
(This article belongs to the Special Issue Plastic Recycling and Biopolymer Synthesis for Industrial Application)
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<p>Mechanical testing of rPET: (<b>a</b>) specimen design and preparation; (<b>b</b>) thickness measurement; (<b>c</b>) testing machine and specimens after testing.</p>
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<p>Consultive behaviour of rPET: (<b>a</b>) JC material model; (<b>b</b>) finite element model of the uniaxial test.</p>
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<p>Manufacture of woven fabrics: (<b>a</b>) representative region; (<b>b</b>) initial configuration of warp and weft yarns; (<b>c</b>) weaving process.</p>
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<p>Finite element model: (<b>a</b>) meshed model; (<b>b</b>) time history of boundary conditions.</p>
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<p>Testing results and material modelling (SC and SL): (<b>a</b>) experimental stress–strain relationship; (<b>b</b>) simulated SC deformation; (<b>c</b>) simulated SL deformation; (<b>d</b>) force–displacement curve.</p>
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<p>Stress distribution of rPET fibres in sequential weaving process (warp: SC, weft: SC): (<b>a</b>) steps of inserting first weft yarn; (<b>b</b>) steps of inserting other weft yarns.</p>
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<p>Stress distribution of rPET fibres in sequential weaving process (warp: SC, weft: SC): (<b>a</b>) steps of inserting first weft yarn; (<b>b</b>) steps of inserting other weft yarns.</p>
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<p>Stress distribution of rPET fibres in different weaving process: (<b>a</b>) warp: SC, weft: SL; (<b>b</b>) warp: SL, weft: SC.</p>
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<p>Reaction force of warp yarns during weaving process: (<b>a</b>) <span class="html-italic">µ</span> = 0.7 (warp: SC, weft: SC); (<b>b</b>) <span class="html-italic">µ</span> = 0.2 (warp: SC, weft: SC); (<b>c</b>) <span class="html-italic">µ</span> = 0.7 (warp: SC, weft: SL); (<b>d</b>) <span class="html-italic">µ</span> = 0.2 (warp: SC, weft: SL).</p>
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25 pages, 20763 KiB  
Article
Research on Maneuvering Motion Prediction for Intelligent Ships Based on LSTM-Multi-Head Attention Model
by Dongyu Liu, Xiaopeng Gao, Cong Huo and Wentao Su
J. Mar. Sci. Eng. 2025, 13(3), 503; https://doi.org/10.3390/jmse13030503 - 5 Mar 2025
Viewed by 54
Abstract
In complex marine environments, accurate prediction of maneuvering motion is crucial for the precise control of intelligent ships. This study aims to enhance the predictive capabilities of maneuvering motion for intelligent ships in such environments. We propose a novel maneuvering motion prediction method [...] Read more.
In complex marine environments, accurate prediction of maneuvering motion is crucial for the precise control of intelligent ships. This study aims to enhance the predictive capabilities of maneuvering motion for intelligent ships in such environments. We propose a novel maneuvering motion prediction method based on Long Short-Term Memory (LSTM) and Multi-Head Attention Mechanisms (MHAM). To construct a foundational dataset, we integrate Computational Fluid Dynamics (CFD) numerical simulation technology to develop a mathematical model of actual ship maneuvering motions influenced by wind, waves, and currents. We simulate typical operating conditions to acquire relevant data. To emulate real marine environmental noise and data loss phenomena, we introduce Ornstein–Uhlenbeck (OU) noise and random occlusion noise into the data and apply the MaxAbsScaler method for dataset normalization. Subsequently, we develop a black-box model for intelligent ship maneuvering motion prediction based on LSTM networks and Multi-Head Attention Mechanisms. We conduct a comprehensive analysis and discussion of the model structure and hyperparameters, iteratively optimize the model, and compare the optimized model with standalone LSTM and MHAM approaches. Finally, we perform generalization testing on the optimized motion prediction model using test sets for zigzag and turning conditions. The results demonstrate that our proposed model significantly improves the accuracy of ship maneuvering predictions compared to standalone LSTM and MHAM algorithms and exhibits superior generalization performance. Full article
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<p>Define the ship’s coordinate system of motion.</p>
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<p>Turning motion data collection: (<b>a</b>) u in still water; (<b>b</b>) v in still water; (<b>c</b>) r in still water; (<b>d</b>) u in wave environment; (<b>e</b>) v in wave environment; and (<b>f</b>) r in wave environment.</p>
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<p>Zigzag motion data collection: (<b>a</b>) u in still water; (<b>b</b>) v in still water; (<b>c</b>) r in still water; (<b>d</b>) u in wave environment; (<b>e</b>) v in wave environment; and (<b>f</b>) r in wave environment.</p>
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<p>Zigzag motion data collection: (<b>a</b>) u in still water; (<b>b</b>) v in still water; (<b>c</b>) r in still water; (<b>d</b>) u in wave environment; (<b>e</b>) v in wave environment; and (<b>f</b>) r in wave environment.</p>
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<p>Training, validation, and testing sets.</p>
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<p>LSTM model unit structure.</p>
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<p>Multi-Head Attention Mechanism structure.</p>
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<p>LSTM-Multi-Head Attention-1 Model Framework.</p>
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<p>LSTM-Multi-Head Attention-2 Model Framework.</p>
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<p>LSTM-Multi-Head Attention-3 Model Framework.</p>
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<p>Forecasting effects of the proposed models.</p>
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<p>RMSE and loss curves of the proposed models.</p>
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<p>Forecasting effects of models with different regularization methods.</p>
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<p>RMSE and loss curves with different regularization methods.</p>
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<p>Forecasting effects of models with different numbers of heads.</p>
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<p>RMSE and loss curves with different numbers of heads.</p>
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<p>Analysis of the impact of the number of neurons on model performance.</p>
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<p>RMSE and loss curves with different number of neurons.</p>
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<p>Forecasting effects of models with different training batch sizes.</p>
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<p>RMSE and loss curves with different training batch sizes.</p>
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<p>Analysis of the Impact of sliding window size.</p>
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<p>RMSE and loss curves with different sliding window size.</p>
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<p>Comparison of prediction effects among LSTM, GRU, Multi-Head Attention, Transformer, and LSTM-Multi-Head Attention-2 models.</p>
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<p>RMSE and loss curves of LSTM, GRU, Multi-Head Attention, Transformer, and LSTM-Multi-Head Attention-2 models.</p>
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<p>Prediction of u, v, r, and heading for an 8-degree turning movement.</p>
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<p>Prediction of u, v, r, and heading for a 15-degree turning movement.</p>
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<p>Prediction of trajectory for 8-degree and 15-degree turning movement.</p>
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<p>Prediction of u, v, r, and heading for 5°/5° Zigzag.</p>
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<p>Prediction of u, v, r, and heading for 5°/5° Zigzag.</p>
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<p>The optimized forecasting effect.</p>
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21 pages, 567 KiB  
Review
Review of Deterministic and AI-Based Methods for Fluid Motion Modelling and Sloshing Analysis
by Grzegorz Filo, Paweł Lempa and Konrad Wisowski
Energies 2025, 18(5), 1263; https://doi.org/10.3390/en18051263 - 4 Mar 2025
Viewed by 165
Abstract
Contemporary fluid motion modelling techniques, including the phenomenon of liquid sloshing in tanks, are increasingly associated with the use of artificial intelligence methods. In addition to the still frequently used traditional analysis methods and techniques, such as FEM, CFD, VOF and FSI, there [...] Read more.
Contemporary fluid motion modelling techniques, including the phenomenon of liquid sloshing in tanks, are increasingly associated with the use of artificial intelligence methods. In addition to the still frequently used traditional analysis methods and techniques, such as FEM, CFD, VOF and FSI, there is an increasing number of publications that use elements of artificial intelligence. Among others, artificial neural networks and deep learning techniques are used here in the field of prediction and approximation, as well as genetic and other multi-agent algorithms for optimization. This article analyses of the current state of research using the above techniques and the possibilities and main directions of their further development. Full article
(This article belongs to the Section B: Energy and Environment)
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<p>Number of publications on liquid sloshing modelling: 1—traditional methods; 2—neural network usage; 3—genetic algorithm applications.</p>
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<p>A diagram of CFD method usage for liquid slosh modelling.</p>
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<p>Diagram representing the CFD method with FSI approach for liquid sloshing simulation.</p>
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<p>Machine learning model diagram for liquid sloshing simulation based on ANNs.</p>
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15 pages, 4516 KiB  
Article
Optimization of Deep Learning Models for Enhanced Respiratory Signal Estimation Using Wearable Sensors
by Jiseon Kim and Jooyong Kim
Processes 2025, 13(3), 747; https://doi.org/10.3390/pr13030747 - 4 Mar 2025
Viewed by 192
Abstract
Measuring breathing changes during exercise is crucial for healthcare applications. This study used wearable capacitive sensors to capture abdominal motion and extract breathing patterns. Data preprocessing methods included filtering and normalization, followed by feature extraction for classification. Despite the growing interest in respiratory [...] Read more.
Measuring breathing changes during exercise is crucial for healthcare applications. This study used wearable capacitive sensors to capture abdominal motion and extract breathing patterns. Data preprocessing methods included filtering and normalization, followed by feature extraction for classification. Despite the growing interest in respiratory monitoring, research on a deep learning-based analysis of breathing data remains limited. To address this research gap, we optimized CNN and ResNet through systematic hyperparameter tuning, enhancing classification accuracy and robustness. The optimized ResNet outperformed the CNN in accuracy (0.96 vs. 0.87) and precision for Class 4 (0.8 vs. 0.6), demonstrating its capability to capture complex breathing patterns. These findings highlight the importance of hyperparameter optimization in respiratory monitoring and suggest ResNet as a promising tool for real-time assessment in medical applications. Full article
(This article belongs to the Special Issue Smart Wearable Technology: Thermal Management and Energy Applications)
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<p>A schematic of the proposed work.</p>
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<p>Abdominal movement in response to breathing [<a href="#B23-processes-13-00747" class="html-bibr">23</a>].</p>
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<p>(<b>a</b>) Wearable sensors in the shape of a finished garment [<a href="#B23-processes-13-00747" class="html-bibr">23</a>]; (<b>b</b>) the effect of single-ply and triple-ply thread length on the resistance value.</p>
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<p>(<b>a</b>) Schematic of LCR meter [<a href="#B23-processes-13-00747" class="html-bibr">23</a>]; (<b>b</b>) measurement of wearable sensors.</p>
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<p>(<b>a</b>) CNN architecture; (<b>b</b>) ResNet architecture.</p>
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<p>Breathing data under different conditions: (<b>a</b>) resting; (<b>b</b>) low intensity; (<b>c</b>) moderate intensity; and (<b>d</b>) high intensity.</p>
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<p>(<b>a</b>) Training results window; (<b>b</b>) confusion matrix (CNN-1).</p>
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<p>The results of O-CNN. (<b>a</b>) Validation accuracy; (<b>b</b>) training loss.</p>
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<p>(<b>a</b>) Training results window; (<b>b</b>) confusion matrix (ResNet-1).</p>
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<p>The results of O-Resnet. (<b>a</b>) Validation accuracy; (<b>b</b>) training loss.</p>
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<p>Confusion matrix of O-CNN.</p>
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<p>Confusion matrix of O-ResNet.</p>
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19 pages, 12844 KiB  
Article
Inter-Software Reproducibility of Quantitative Values of Myocardial Blood Flow and Coronary Flow Reserve Acquired by [13N]NH3 MPI PET/CT and the Effect of Motion Correction Tools
by Oscar Isaac Mendoza-Ibañez, Riemer H. J. A. Slart, Erick Alexanderson-Rosas, Tonantzin Samara Martinez-Lucio, Friso M. van der Zant, Remco J. J. Knol and Sergiy V. Lazarenko
Diagnostics 2025, 15(5), 613; https://doi.org/10.3390/diagnostics15050613 - 4 Mar 2025
Viewed by 79
Abstract
Background: The choice of software package (SP) for image processing affects the reproducibility of myocardial blood flow (MBF) values in [13N]NH3 PET/CT scans. However, the impact of motion correction (MC) tools—integrated software motion correction (ISMC) or data-driven motion correction (DDMC)—on [...] Read more.
Background: The choice of software package (SP) for image processing affects the reproducibility of myocardial blood flow (MBF) values in [13N]NH3 PET/CT scans. However, the impact of motion correction (MC) tools—integrated software motion correction (ISMC) or data-driven motion correction (DDMC)—on the inter-software reproducibility of MBF has not been studied. This research aims to evaluate reproducibility among three commonly used SPs and the role of MC. Methods: Thirty-six PET/CT studies from patients without myocardial ischemia or infarction were processed using QPET, Corridor-4DM (4DM), and syngo.MBF (syngo). MBF and coronary flow reserve (CFR) values were obtained without motion correction (NMC) and with ISMC and DDMC. Intraclass correlation coefficients (ICC) and Bland-Altman (BA) plots were used to analyze agreement. Results: Good or excellent reproducibility (ICC ≥ 0.77) was found for rest-MBF values, regardless of the SPs or use of MC. In contrast, stress-MBF and CFR values presented mostly a moderate agreement when NMC was used. The RCA territory consistently had the lowest agreement in stress-MBF and CFR in the comparisons involving QPET. The use of MC, particularly DDMC, enhanced the reproducibility of most of the stress-MBF and CFR values by improving ICCs and reducing bias and limits of agreement (LoA) in BA analysis. Conclusions: MBF quantification agreement between SPs is strong for rest-MBF values but suboptimal for stress-MBF and CFR values. MC tools, especially DDMC, are recommended for improving reproducibility in stress-MBF assessments, although differences in SP reproducibility up to 0.77 mL/g/min in global stress-MBF and up to 0.88 in global CFR remain despite the use of MC. Full article
(This article belongs to the Special Issue PET/CT Diagnostics and Theranostics)
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<p>Functioning of the DDMC algorithm. (<b>A</b>) Direct Volume Histogram (DVH) constructed by the DDMC at sec = 85. (<b>B</b>) Process of heart signature (REF) detection in DDMC. The red box denoted the REF located within a predefined search range (SER) [gray box]. (<b>C</b>) DDMC normalized cross-correlation (NCC) matches in a stress acquisition up to sec = 250. The red solid line denotes the threshold of 85% established to assure reliable motion tracking. Blue solid line reflects the blood-pool period, where tracking is more difficult and sometimes unreliable. (<b>D</b>) Motion vector constructed by DDMC in the Z-direction of the second half of a stress acquisition.</p>
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<p>Flowchart of the methodological process for the acquisition of final variables and formal statistical analysis of the data.</p>
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<p>BA analysis of LAD rest-MBF values in the paired comparison of QPET and 4DM. Note how the bias (mean error) [black solid line], range of limits of agreement (LoA) [black dotted line], and minimal detectable change (MDC) are not modified in a significant extent by the use of ISMC (<b>B</b>) or DDMC (<b>C</b>) when compared to the original NMC approach (<b>A</b>).</p>
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<p>BA analysis of regional stress-MBF values in the paired comparison of QPET and 4DM. Note how the bias (mean error) [black solid line] is modified in a significant extent by the use of ISMC (<b>B</b>) or DDMC (<b>C</b>), when compared to the original NMC approach (<b>A</b>). It is important to notice how the range of the limits of agreement (LoA) [black dotted lines] and minimal detectable change (MDC) are reduced considerably when using MC tools.</p>
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<p>BA analysis of global CFR values in the paired comparison of QPET and 4DM. Note how the bias (mean error) [black solid line] becomes closer to the zero mean difference line after the use of ISMC (<b>B</b>) or DDMC (<b>C</b>) when compared to the original NMC approach (<b>A</b>). Note how the range in limits of agreement (LoA) [black dotted lines] and minimal detectable change (MDC) are also reduced considerably when using MC tools.</p>
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