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17 pages, 3345 KiB  
Article
Spatial-Temporal Evolution of Maritime Accident Hot Spots in the East China Sea: A Space-Time Cube Representation
by Yiyang Feng, Daozheng Huang, Xijie Hong, Huanxin Wang, Sean Loughney and Jin Wang
J. Mar. Sci. Eng. 2025, 13(2), 233; https://doi.org/10.3390/jmse13020233 - 26 Jan 2025
Viewed by 470
Abstract
As public concern for maritime safety grows, there is a pressing need to delve deeper into the root causes of maritime accidents and develop effective preventive strategies. Spatial-temporal analysis stands out as a powerful approach to pinpointing accident hot spots. While previous research [...] Read more.
As public concern for maritime safety grows, there is a pressing need to delve deeper into the root causes of maritime accidents and develop effective preventive strategies. Spatial-temporal analysis stands out as a powerful approach to pinpointing accident hot spots. While previous research has shed light on the spatial aspects of these incidents, a comprehensive understanding of their temporal dimensions remains elusive. This paper bridges this gap by leveraging the Space-Time Cube tool in conjunction with traditional Kernel Density analysis to chart the spatial-temporal dynamics of maritime accident hot spots. Focusing on the East China Sea, a region notorious for its high incidence of maritime accidents and home to numerous world-class ports, we present a case study that offers fresh insights. Data spanning from 1994 to 2020, sourced from the Lloyd’s List Intelligence (LLI) database, reveal the evolving landscape of maritime accidents in the area. Notably, since 2005, the Yangtze River Delta Region in China has emerged as a persistent hot spot for accidents, underscoring its significance in maritime safety discourse. Furthermore, our analysis from the 2010s detects a new hot spot expanding towards the southwest of Kaohsiung Port, China, signaling a burgeoning area of concern for maritime safety. While the Fujian coast of China has seen its share of accidents, it is not qualified as a hot spot zone. The Space-Time Cube proves to be an indispensable tool in unraveling the progression of maritime accidents, and our findings indicate that maritime accidents in certain areas may not be merely random occurrences but exhibit intricate patterns. Full article
(This article belongs to the Section Ocean Engineering)
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<p>The spatial distributions of maritime accidents in the East China Sea.</p>
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<p>Trend of maritime accidents in two main areas from 1994 to 2020.</p>
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<p>Container throughput of four major ports on the East China Sea.</p>
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<p>Framework of spatial-temporal evolution analysis.</p>
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<p>Results of the Space-Time Cube in the East China Sea.</p>
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<p>Space-Time Cube in 3D view.</p>
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<p>Results of the Kernel Density analysis in the East China Sea.</p>
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12 pages, 2427 KiB  
Article
Racial and Geographic Disparities in Colorectal Cancer Incidence and Associated County-Level Risk Factors in Mississippi, 2003–2020: An Ecological Study
by Shamim Sarkar, Sasha McKay, Jennie L. Williams and Jaymie R. Meliker
Cancers 2025, 17(2), 192; https://doi.org/10.3390/cancers17020192 - 9 Jan 2025
Viewed by 687
Abstract
Introduction: Colorectal cancer (CRC) is the third most commonly diagnosed cancer in the United States (U.S.). Mississippi has the highest rate of CRC incidence in the U.S. and has large populations of black and white individuals, allowing for studies of racial disparities. Methods: [...] Read more.
Introduction: Colorectal cancer (CRC) is the third most commonly diagnosed cancer in the United States (U.S.). Mississippi has the highest rate of CRC incidence in the U.S. and has large populations of black and white individuals, allowing for studies of racial disparities. Methods: We conducted an ecological study using the county as the unit of analysis. CRC incidence data at the county level for black and white populations in Mississippi, covering the years 2003 to 2020, were retrieved from the Mississippi Cancer Registry. Age-adjusted incidence rate differences and their corresponding 95% confidence intervals (CIs) were then calculated for these groups. Getis–Ord Gi* hot and cold spot analysis of CRC incidence rate racial disparities was performed using ArcGIS Pro. We used global ordinary least square regression and geographically weighted regression (MGWR version 2.2) to identify factors associated with racial differences in CRC incidence rates. Results: Age-adjusted CRC incidence rate in the black population (median = 58.12/100,000 population) and in the white population (median = 46.44/100,000 population) varied by geographical area. Statistically significant racial differences in CRC incidence rates were identified in 28 counties, all of which showed higher incidence rates among the black population compared to the white population. No hot spots were detected, indicating that there were no spatial clusters of areas with pronounced racial disparities. As a post hoc analysis, after considering multicollinearity and a directed acyclic graph, a parsimonious multiple regression model showed an association (β = 0.93, 95% CI: 0.25, 1.62) indicating that a 1% increase in food insecurity was associated with a 0.93/100,000 differential increase in the black–white CRC incidence rate. Geographically weighted regression did not reveal any local patterns in this association. Conclusions: Black–white racial disparities in CRC incidence were found in 28 counties in Mississippi. The county-level percentage of food insecurity emerged as a possible predictor of the observed black–white racial disparities in CRC incidence rates. Individual-level studies are needed to clarify whether food insecurity is a driver of these disparities or a marker of systemic disadvantage in these counties. Full article
(This article belongs to the Special Issue Feature Paper in Section 'Cancer Epidemiology and Prevention' in 2024)
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Figure 1
<p>Geographic distribution of potential predictors (percent smoking, percent obesity, percent uninsured, percent physical inactivity, median income, percent food insecurity, and percent diabetes mellitus) of county-level colorectal cancer incidence rate difference per 100,000, between black and white populations in Mississippi counties, 2003–2020.</p>
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<p>Colorectal cancer incidence rates (2003–2020) among black and white populations by county. Data were obtained from the Mississippi Cancer Registry: (<b>A</b>) age-adjusted incidence rate (per 100,000) of colorectal cancer among the black population at the county level; (<b>B</b>) age-adjusted incidence rate (per 100,000) of colorectal cancer among the white population at the county level.</p>
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<p>Colorectal cancer incidence rate differences per 100,000, between black and white populations in Mississippi counties, 2003–2020. Counties with significant rate differences (RDs) are indicated with a wider blue circle <span class="html-fig-inline" id="cancers-17-00192-i001"><img alt="Cancers 17 00192 i001" src="/cancers/cancers-17-00192/article_deploy/html/images/cancers-17-00192-i001.png"/></span>.</p>
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27 pages, 10112 KiB  
Article
Mapping Urban Changes Through the Spatio-Temporal Analysis of Vegetation and Built-Up Areas in Iași, Romania
by Cristian-Manuel Foșalău, Lucian Roșu, Corneliu Iațu, Oliver-Valentin Dinter and Petru-Mihai Cristodulo
Sustainability 2025, 17(1), 11; https://doi.org/10.3390/su17010011 - 24 Dec 2024
Viewed by 1090
Abstract
Vegetation cover in urban and peri-urban areas is threatened by urban sprawl, through habitat fragmentation, loss of green space, biodiversity reduction, and the urban heat island effect intensifying. The intrusion of cities into natural landscapes reduces vital ecosystem services provided by vegetation. Hence, [...] Read more.
Vegetation cover in urban and peri-urban areas is threatened by urban sprawl, through habitat fragmentation, loss of green space, biodiversity reduction, and the urban heat island effect intensifying. The intrusion of cities into natural landscapes reduces vital ecosystem services provided by vegetation. Hence, sustainable and integrated urban planning practices are required. Our study aims to investigate the dynamics of the urban and peri-urban fabric by exploring the relationship between the green fabric distribution and recent trends in urban expansion, focusing specifically on the peri-urban areas of Iași Municipality, Romania. We designed a mixed-method approach combining a multivariate analysis of four critical indicators (vegetation cover, built-up space, land surface temperature, and population density), emerging hot-spots, and space-time cubes in a GIS environment to achieve our research aims. Our results demonstrate that uncontrolled urban expansion has manifested in diverse patterns, impacting territories next to road transport networks and with construction-suitable topography. Concurrently, the development of green spaces prevails in forests and unexpected locations such as brownfields, railway corridors, and old industrial zones, through the growth of urban greenery. This approach provides a comprehensive understanding of how urban sprawl impacts the environment and how different land types are prone to this transformation, creating a path towards sustainability, resilience, and equitable development. Full article
(This article belongs to the Special Issue Urban Green Areas: Benefits, Design and Management Strategies)
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<p>Study area.</p>
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<p>Methodological framework.</p>
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<p>Vegetation oscillation patterns.</p>
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<p>Evolution of average built-up space per cluster.</p>
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<p>Map of the built-up clusters.</p>
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<p>Map of the multivariate analysis clusters.</p>
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<p>The size of the six clusters.</p>
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<p>Multivariate clustering boxplots.</p>
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<p>Map of the vegetation cover evolution (1987–2023).</p>
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<p>NDVI in correlation to built-up space evolutions (1987–2023).</p>
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16 pages, 2808 KiB  
Article
Spatial Variation and Predictors of Women’s Sole Autonomy in Healthcare Decision-Making in Bangladesh: A Spatial and Multilevel Analysis
by Satyajit Kundu, Md Hafizur Rahman, Syed Sharaf Ahmed Chowdhury, John Elvis Hagan, Susmita Rani Dey, Rakhi Dey, Rita Karmoker, Azaz Bin Sharif and Faruk Ahmed
Healthcare 2024, 12(24), 2494; https://doi.org/10.3390/healthcare12242494 - 10 Dec 2024
Viewed by 725
Abstract
Background: Knowing the spatial variation and predictors of women having sole autonomy over their healthcare decisions is crucial to design site-specific interventions. This study examined how women’s sole autonomy over their healthcare choices varies geographically and what factors influence this autonomy among Bangladeshi [...] Read more.
Background: Knowing the spatial variation and predictors of women having sole autonomy over their healthcare decisions is crucial to design site-specific interventions. This study examined how women’s sole autonomy over their healthcare choices varies geographically and what factors influence this autonomy among Bangladeshi women of childbearing age. Methods: Data were obtained from the Bangladesh Demographic and Health Survey (BDHS) 2017–18. The final analysis included data from a total of 18,890 (weighted) women. Spatial distribution, hot spot analysis, ordinary Kriging interpolation, and multilevel multinomial regression analysis were employed. Results: The study found that approximately one in ten women (9.62%) exercised complete autonomy in making decisions about their healthcare. Spatial analysis revealed a significant clustering pattern in this autonomy (Moran’s I = 0.234, p < 0.001). Notably, three divisions—Barisal, Chittagong, and Sylhet—emerged as hot spots where women were more likely to have sole autonomy over their healthcare choices. In contrast, the cold spots (poor level of sole healthcare autonomy by women) were mainly identified in Mymensingh and Rangpur divisions. Women in the age group of 25–49 years, who were highly educated, Muslim, urban residents, and had not given birth recently were more likely to have sole autonomy in making healthcare decisions for themselves. Conversely, women whose husbands were highly educated and employed, as well as those who were pregnant, were less likely to have sole autonomy over their healthcare choices. Conclusions: Since the spatial distribution was clustered, public health interventions should be planned to target the cold spot areas of women’s sole healthcare autonomy. In addition, significant predictors contributing to women’s sole healthcare autonomy must be emphasized while developing interventions to improve women’s empowerment toward healthcare decision-making. Full article
(This article belongs to the Section Women's Health Care)
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<p>Global spatial autocorrelation report showing the women’s sole decision-making autonomy in healthcare in Bangladesh (map was generated using ArcGIS v 10.8 software).</p>
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<p>Spatial clustering (hot spot and cold spot) of women’s sole decision-making autonomy in healthcare in Bangladesh (map was generated using ArcGIS v 10.8 software).</p>
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<p>Spatial interpolation of women’s sole autonomy in healthcare decision-making in Bangladesh (map was generated using ArcGIS v 10.8 software).</p>
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24 pages, 5443 KiB  
Article
Efficient Numerical Modeling of Oil-Immersed Transformers: Simplified Approaches to Conjugate Heat Transfer Simulation
by Ivan Smolyanov and Evgeniy Shmakov
Modelling 2024, 5(4), 1865-1888; https://doi.org/10.3390/modelling5040097 - 2 Dec 2024
Viewed by 734
Abstract
The development of digital twins for power transformers has become increasingly important to predict possible operating modes and reduce the likelihood of faults. The accuracy of these predictions relies heavily on the numerical models used, which must be both simple and computationally efficient. [...] Read more.
The development of digital twins for power transformers has become increasingly important to predict possible operating modes and reduce the likelihood of faults. The accuracy of these predictions relies heavily on the numerical models used, which must be both simple and computationally efficient. This work focuses on creating a simplified numerical model for a template oil-immersed power transformer (100 MVA, 230/69 KV). The study investigates how the number of elements and the strategies used to set up the mesh in the domain of interest influence the results, aiming to identify the key parameters that affect the outcomes. Furthermore, a significant effect of resolving thermal boundary layers on the accurate identification of hot spots is demonstrated. Two approaches to resolving thermal boundary layers are explored in this work. This study presents a comprehensive analysis of three numerical models for conjugate heat transfer simulations, each with distinct features and computational domain compositions. The results show that the addition of extra calculation domains leads to the emergence of new vortex structures, affecting the velocity profile at the channel inlet and altering the location of hot spots. This study provides valuable insights into the configuration and composition of calculated domains in numerical models of oil-immersed power transformers, essential for the accurate prediction of hot spot temperatures and ensuring reliable operation. Full article
(This article belongs to the Special Issue Finite Element Simulation and Analysis)
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Figure 1
<p>Schematic representation of an idealized 100 MVA, 230/69 kV power transformer.</p>
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<p>Sliced sketch of numerical model’s geometry.</p>
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<p>Temperature dependence of oil density.</p>
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<p>Mesh illustrating the discretization of the problem domain into sub-domains for numerical analysis. Figure (<b>a</b>) shows a general view of the mesh, highlighting the main mesh parameters. Figures (<b>b</b>,<b>c</b>) present a zoomed-in view of a section of the left channel, demonstrating the resolution of thermal boundary layers using the implicit and explicit approaches, respectively.</p>
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<p>Time-dependent maximum velocity at (<b>a</b>) the inlet of the left duct, (<b>b</b>) the middle duct and (<b>c</b>) the right duct under heat load coefficient <math display="inline"><semantics> <mrow> <msub> <mi>k</mi> <mi>heat</mi> </msub> <mo>=</mo> <mn>1</mn> </mrow> </semantics></math>. The black, orange and green colors mean the radial discretizations in 10, 20 and 30 elements, correspondingly. The solid, dotted and dashed line styles represent the azimutal discretizations in 100, 200 and 300 elements, correspondingly, for each color’s corresponding radial discretizations.</p>
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<p>The maximum temperature on the low- (<b>a</b>) and high-voltage (<b>b</b>) windings is dependent on time under the heat load coefficient <math display="inline"><semantics> <mrow> <msub> <mi>k</mi> <mrow> <mi>h</mi> <mi>e</mi> <mi>a</mi> <mi>t</mi> </mrow> </msub> <mo>=</mo> <mn>1</mn> </mrow> </semantics></math>. The black, orange and green colors mean the radial discretizations in the 10, 20 and 30 elements, correspondingly. The solid, dotted and dashed line styles represent the azimutal discretizations in 100, 200 and 300 elements, correspondingly, for each color’s corresponding radial discretizations.</p>
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<p>Time-dependent maximum velocity at (<b>a</b>) the inlet of the left duct, (<b>b</b>) the middle duct and (<b>c</b>) the right duct under heat load coefficient <math display="inline"><semantics> <mrow> <msub> <mi>k</mi> <mi>heat</mi> </msub> <mo>=</mo> <mn>10</mn> </mrow> </semantics></math>. The black, orange and green colors mean the radial discretizations in 10, 20 and 30 elements, correspondingly. The solid, dotted and dashed line styles represent the azimutal discretizations in 100, 200 and 300 elements, correspondingly, for each color’s corresponding radial discretizations.</p>
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<p>The maximum temperature on the low- (<b>a</b>) and high-voltage (<b>b</b>) windings, dependent on time under the heat load coefficient <math display="inline"><semantics> <mrow> <msub> <mi>k</mi> <mrow> <mi>h</mi> <mi>e</mi> <mi>a</mi> <mi>t</mi> </mrow> </msub> <mo>=</mo> <mn>10</mn> </mrow> </semantics></math>. The black, orange and green colors mean the radial discretizations in 10, 20 and 30 elements, correspondingly. The solid, dotted and dashed line styles represent the azimutal discretizations in 100, 200 and 300 elements, correspondingly, for each color’s corresponding radial discretizations.</p>
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<p>Relative differences in percent of calculated temperature and velocity. The sensitivity of temperature and velocity are measured dependent on the number of elements in the radial direction for the thermal boundary layer (<b>a</b>), flow core (<b>b</b>) and solid parts (<b>c</b>), and in the azimuthal direction (<b>d</b>). The simulation is conducted for <math display="inline"><semantics> <mrow> <msub> <mi>k</mi> <mrow> <mi>h</mi> <mi>e</mi> <mi>a</mi> <mi>t</mi> </mrow> </msub> <mo>=</mo> <mn>10</mn> </mrow> </semantics></math>. The graphs are drawn with two different colors of axes for matching scales of temperature and velocity. The blue color corresponds to the velocity curve and the red to the temperature one.</p>
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<p>Velocity (<b>a</b>) and temperature (<b>b</b>) profiles at the inlet of the right channel for <math display="inline"><semantics> <mrow> <msub> <mi>k</mi> <mrow> <mi>h</mi> <mi>e</mi> <mi>a</mi> <mi>t</mi> </mrow> </msub> <mo>=</mo> <mn>10</mn> </mrow> </semantics></math>, with different mesh resolutions in the thermal boundary layer: 4, 10 and 40 elements.</p>
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<p>The velocity profile at the inlet of the right channel. The simulation is conducted for <math display="inline"><semantics> <mrow> <msub> <mi>k</mi> <mrow> <mi>h</mi> <mi>e</mi> <mi>a</mi> <mi>t</mi> </mrow> </msub> <mo>=</mo> <mn>10</mn> </mrow> </semantics></math> and the number of mesh elements in azimuthal direction; 20, 100, 200 and 400.</p>
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<p>The average velocity at the outlets of the left (<b>a</b>), middle (<b>b</b>) and right (<b>c</b>) channels over time for heat load coefficient <math display="inline"><semantics> <mrow> <msub> <mi>k</mi> <mrow> <mi>h</mi> <mi>e</mi> <mi>a</mi> <mi>t</mi> </mrow> </msub> <mo>=</mo> <mn>1</mn> <mo>,</mo> <mn>5</mn> <mo>,</mo> <mn>10</mn> </mrow> </semantics></math>. The velocity curves are calculated by 3 different numerical models. A detailed description of these models is provided in <a href="#sec2dot2-modelling-05-00097" class="html-sec">Section 2.2</a>.</p>
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<p>The maximum temperature in low- (<b>a</b>) and high-voltage (<b>b</b>) windings over time for heat load coefficient <math display="inline"><semantics> <msub> <mi>k</mi> <mrow> <mi>h</mi> <mi>e</mi> <mi>a</mi> <mi>t</mi> </mrow> </msub> </semantics></math> = 1, 5, 10. The velocity curves are calculated by 3 different numerical models. A detailed description of these models is provided in <a href="#sec2dot2-modelling-05-00097" class="html-sec">Section 2.2</a>.</p>
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<p>Velocity distribution in the oil and temperature distribution in the solid components of the transformer, calculated using three different models. Results for <math display="inline"><semantics> <mrow> <msub> <mi>k</mi> <mrow> <mi>h</mi> <mi>e</mi> <mi>a</mi> <mi>t</mi> </mrow> </msub> <mo>=</mo> <mn>1</mn> </mrow> </semantics></math> are shown in subfigures (<b>a</b>–<b>c</b>), and results for <math display="inline"><semantics> <mrow> <msub> <mi>k</mi> <mrow> <mi>h</mi> <mi>e</mi> <mi>a</mi> <mi>t</mi> </mrow> </msub> <mo>=</mo> <mn>10</mn> </mrow> </semantics></math> are shown in subfigures (<b>d</b>–<b>f</b>).</p>
Full article ">Figure 14 Cont.
<p>Velocity distribution in the oil and temperature distribution in the solid components of the transformer, calculated using three different models. Results for <math display="inline"><semantics> <mrow> <msub> <mi>k</mi> <mrow> <mi>h</mi> <mi>e</mi> <mi>a</mi> <mi>t</mi> </mrow> </msub> <mo>=</mo> <mn>1</mn> </mrow> </semantics></math> are shown in subfigures (<b>a</b>–<b>c</b>), and results for <math display="inline"><semantics> <mrow> <msub> <mi>k</mi> <mrow> <mi>h</mi> <mi>e</mi> <mi>a</mi> <mi>t</mi> </mrow> </msub> <mo>=</mo> <mn>10</mn> </mrow> </semantics></math> are shown in subfigures (<b>d</b>–<b>f</b>).</p>
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<p>Velocity distribution in the oil and temperature distribution in the solid components of the transformer, calculated by models #2 and #3 for different heat load coefficients: <math display="inline"><semantics> <mrow> <msub> <mi>k</mi> <mrow> <mi>h</mi> <mi>e</mi> <mi>a</mi> <mi>t</mi> </mrow> </msub> <mo>=</mo> <mn>1</mn> </mrow> </semantics></math> and <math display="inline"><semantics> <mrow> <msub> <mi>k</mi> <mrow> <mi>h</mi> <mi>e</mi> <mi>a</mi> <mi>t</mi> </mrow> </msub> <mo>=</mo> <mn>10</mn> </mrow> </semantics></math>. The distributions are calculated by (<b>a</b>) model #2 <math display="inline"><semantics> <mrow> <msub> <mi>k</mi> <mrow> <mi>h</mi> <mi>e</mi> <mi>a</mi> <mi>t</mi> </mrow> </msub> <mo>=</mo> <mn>1</mn> </mrow> </semantics></math>, (<b>b</b>) model #2 <math display="inline"><semantics> <mrow> <msub> <mi>k</mi> <mrow> <mi>h</mi> <mi>e</mi> <mi>a</mi> <mi>t</mi> </mrow> </msub> <mo>=</mo> <mn>10</mn> </mrow> </semantics></math>, (<b>c</b>) model #3 <math display="inline"><semantics> <mrow> <msub> <mi>k</mi> <mrow> <mi>h</mi> <mi>e</mi> <mi>a</mi> <mi>t</mi> </mrow> </msub> <mo>=</mo> <mn>1</mn> </mrow> </semantics></math> and (<b>d</b>) model #3 <math display="inline"><semantics> <mrow> <msub> <mi>k</mi> <mrow> <mi>h</mi> <mi>e</mi> <mi>a</mi> <mi>t</mi> </mrow> </msub> <mo>=</mo> <mn>10</mn> </mrow> </semantics></math>.</p>
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<p>The magnitude of the velocity profile on the left (<b>a</b>), middle (<b>b</b>) and right (<b>c</b>) inlets and the left (<b>d</b>), middle (<b>e</b>) and right (<b>f</b>) outlets of the channel calculated by the three models for a heat load coefficient <math display="inline"><semantics> <msub> <mi>k</mi> <mrow> <mi>h</mi> <mi>e</mi> <mi>a</mi> <mi>t</mi> </mrow> </msub> </semantics></math> from 1 to 10. The colors of the lines indicate the value of heat load coefficient and line styles depict the corresponding numerical model.</p>
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<p>The relative velocity deviation between the finest mesh and the one built by optimal parameters in this study.</p>
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18 pages, 3891 KiB  
Article
Identification and Ranking of Binding Sites from Structural Ensembles: Application to SARS-CoV-2
by Maria Lazou, Ayse A. Bekar-Cesaretli, Sandor Vajda and Diane Joseph-McCarthy
Viruses 2024, 16(11), 1647; https://doi.org/10.3390/v16111647 - 22 Oct 2024
Viewed by 2464
Abstract
Target identification and evaluation is a critical step in the drug discovery process. Although time-intensive and complex, the challenge becomes even more acute in the realm of infectious disease, where the rapid emergence of new viruses, the swift mutation of existing targets, and [...] Read more.
Target identification and evaluation is a critical step in the drug discovery process. Although time-intensive and complex, the challenge becomes even more acute in the realm of infectious disease, where the rapid emergence of new viruses, the swift mutation of existing targets, and partial effectiveness of approved antivirals can lead to outbreaks of significant public health concern. The COVID-19 pandemic, caused by the SARS-CoV-2 virus, serves as a prime example of this, where despite the allocation of substantial resources, Paxlovid is currently the only effective treatment. In that case, significant effort pre-pandemic had been expended to evaluate the biological target for the closely related SARS-CoV. In this work, we utilize the computational hot spot mapping method, FTMove, to rapidly identify and rank binding sites for a set of nine SARS-CoV-2 drug/potential drug targets. FTMove takes into account protein flexibility by mapping binding site hot spots across an ensemble of structures for a given target. To assess the applicability of the FTMove approach to a wide range of drug targets for viral pathogens, we also carry out a comprehensive review of the known SARS-CoV-2 ligandable sites. The approach is able to identify the vast majority of all known sites and a few additional sites, which may in fact be yet to be discovered as ligandable. Furthermore, a UMAP analysis of the FTMove features for each identified binding site is largely able to separate predicted sites with experimentally known binders from those without known binders. These results demonstrate the utility of FTMove to rapidly identify actionable sites across a range of targets for a given indication. As such, the approach is expected to be particularly useful for assessing target binding sites for any emerging pathogen, as well as for indications in other disease areas, and providing actionable starting points for structure-based drug design efforts. Full article
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Graphical abstract

Graphical abstract
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<p>Superposition of SARS-CoV-2 Spike GP with its Receptor Binding Domain (RBD) in the open and closed conformations. A structure with one monomer of the RBD in the open conformation (PDB ID 7DK3) is shown in magenta, and a structure with all three monomers of the RBD in the closed conformation (PDB ID 6VXX) is in cyan.</p>
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<p>Structures of the eight targets shown in a surface representation, with experimentally known binding sites highlighted by label/category. In (<b>a</b>) is shown Mpro (PDB ID: 7S82), (<b>b</b>) RdRp (PDB ID: 7ED5), (<b>c</b>) PLPro (PDB ID: 6WX4), (<b>d</b>) JAK1 (PDB ID: 4EHZ), (<b>e</b>) JAK2 (PDB ID: 2XA4), (<b>f</b>) JAK3 (PDB ID: 5TTV), (<b>g</b>) TMPRSS (PDB ID: 7MEQ), and (<b>h</b>) eEF1a (PDB ID: 6ZM0). Red residues correspond to active site, purple to allosteric site, green to adjacent (to active) site, yellow for protein–protein interaction site, pink for nucleic acid binding site, and blue for miscellaneous site.</p>
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<p>Structures of the Spike GP shown in surface representation with known ligandable binding sites highlighted by label/category. Shown in (<b>a</b>) is a Spike GP closed structure (PDB ID: 6ZB5.A) with known binding sites, and in (<b>b</b>) is an open structure (PDB ID: 6XM0.B) with known binding sites. In (<b>c</b>) is a structure of the Spike GP RBD (PDB ID: 6M0J.B) with known binding sites shown. Red residues correspond to active site, purple to allosteric site, green to adjacent (to active) site, yellow for protein–protein interaction site, pink for nucleic acid binding site, and blue for miscellaneous site.</p>
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<p>Alignment of open conformations of Spike GP monomers can yield large RMSDs for the Receptor Binding Motif (RBM) region. In (<b>a</b>), alignment of the 92 open monomers is shown, with the reference structure and the one with the largest RMSD from that for the RBM highlighted in the ribbon diagram, and (<b>b</b>) zooms in on the Receptor Binding Domain (RBD) region. The pairwise alpha-carbon RMSD of the RBM after alignment ranges from 0 to 18 Å. The RBM is the region of the Spike GP RBD that interacts with the ACE2 receptor.</p>
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<p>Recall in the Top X ranking by FTMove of sites with experimentally known binders for each target.</p>
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<p>Correlation of each feature with manual ligandability label. The correlation scale is from red (1) to blue (0).</p>
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<p>UMAP projection of FTMove site feature vectors. In (<b>a</b>) FTMove sites colored by their binary label of ligandable vs. not. In (<b>b</b>) binding sites colored by their category or specific label. Across the eight targets, a total of 81 FTMove sites are plotted.</p>
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<p>Sensitivity of UMAP components to each feature.</p>
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<p>Effect of structure quality on hot spot score at the active site of Mpro. The number of probe clusters (MAX) in the FTMap hot spot corresponding to the active site of Mpro is plotted vs. structure resolution for each of the 293 structures of Mpro analyzed by FTMove. Points are colored by the method of structure determination.</p>
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25 pages, 13903 KiB  
Article
Quantitative Analysis about the Spatial Heterogeneity of Water Conservation Services Function Using a Space–Time Cube Constructed Based on Ecosystem and Soil Types
by Yisheng Liu, Peng Hou, Ping Wang, Jian Zhu, Jun Zhai, Yan Chen, Jiahao Wang and Le Xie
Diversity 2024, 16(10), 638; https://doi.org/10.3390/d16100638 - 14 Oct 2024
Viewed by 715
Abstract
Precisely delineating the spatiotemporal heterogeneity of water conservation services function (WCF) holds paramount importance for watershed management. However, the existing assessment techniques exhibit common limitations, such as utilizing only multi-year average values for spatial changes and relying solely on the spatial average values [...] Read more.
Precisely delineating the spatiotemporal heterogeneity of water conservation services function (WCF) holds paramount importance for watershed management. However, the existing assessment techniques exhibit common limitations, such as utilizing only multi-year average values for spatial changes and relying solely on the spatial average values for temporal changes. Moreover, traditional research does not encompass all WCF values at each time step and spatial grid, hindering quantitative analysis of spatial heterogeneity in WCF. This study addresses these limitations by utilizing an improved water balance model based on ecosystem type and soil type (ESM-WBM) and employing the EFAST and Sobol’ method for parameter sensitivity analysis. Furthermore, a space–time cube of WCF, constructed using remote-sensing data, is further explored by Emerging Hot Spot Analysis for the expression of WCF spatial heterogeneity. Additionally, this study investigates the impact of two core parameters: neighborhood distance and spatial relationship conceptualization type. The results reveal that (1) the ESM-WBM model demonstrates high sensitivity toward ecosystem types and soil data, facilitating the accurate assessment of the impacts of ecosystem and soil pattern alterations on WCF; (2) the EHSA categorizes WCF into 17 patterns, which in turn allows for adjustments to ecological compensation policies in related areas based on each pattern; and (3) neighborhood distance and the type of spatial relationships conceptualization significantly impacts the results of EHSA. In conclusion, this study offers references for analyzing the spatial heterogeneity of WCF, providing a theoretical foundation for regional water resource management and ecological restoration policies with tailored strategies. Full article
(This article belongs to the Special Issue Habitat Assessment and Conservation Strategies)
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<p>Spatial distribution of the ecosystem and elevation in the study area.</p>
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<p>The flowchart of investigation.</p>
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<p>Schematic diagram of ESM: runoff depth and comprehensive runoff index (Ri) calculation principles.</p>
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<p>Schematic diagram of construction principle of the space–time cube.</p>
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<p>The main types of spatial relationship conceptualizations in EHSA, including (<b>a</b>) Fixed Distance, (<b>b</b>) K Nearest Neighbors, (<b>c</b>) Contiguity Edge Only, and (<b>d</b>) Contiguity Edges Corners.</p>
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<p>Spatial distribution of average annual (<b>a</b>) precipitation, (<b>b</b>) actual evapotranspiration, and WCF from (<b>c</b>) 2012 to (<b>d</b>) 2022.</p>
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<p>Spatial distribution of WCF importance grade of the YRB. Grade Ⅰ: generally important 0–223 mm; grade Ⅱ: slightly important, 223–278 mm; grade Ⅲ: moderately important, 278–325 mm; grade Ⅳ: highly important, 325–378 mm; and grade Ⅴ: extremely important, &gt;378 mm (378–538 mm).</p>
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<p>Inter-annual WCF variation averaged from 2012 to 2022 over the sub-watershed.</p>
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<p>Slope of WCF variation from 2012 to 2022.</p>
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<p>The parameters’ sensitivity analysis by EFAST and Sobol’ method, including (<b>a</b>) the Major (First order) Sensitivity Index and (<b>b</b>) the Total Sensitivity Index.</p>
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<p>Spatiotemporal heterogeneity of (<b>a</b>) WCF and (<b>b</b>) specific proportion of 17 EHSA patterns.</p>
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<p>(<b>a</b>) The spatial heterogeneity and (<b>b</b>) transfer characteristics of each pattern from 100 to 150, 150 to 200, 200 to 250 m.</p>
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<p>(<b>a</b>) Spatial distribution and (<b>b</b>) major patterns’ proportions of 4 types of spatial relationships conceptualization.</p>
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<p>(<b>a</b>) Spatial distribution and (<b>b</b>) major patterns’ proportions of 4 types of spatial relationships conceptualization.</p>
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16 pages, 15468 KiB  
Article
Contextual Enrichment of Crowds from Mobile Phone Data through Multimodal Geo-Social Media Analysis
by Klára Honzák, Sebastian Schmidt, Bernd Resch and Philipp Ruthensteiner
ISPRS Int. J. Geo-Inf. 2024, 13(10), 350; https://doi.org/10.3390/ijgi13100350 - 3 Oct 2024
Viewed by 1484
Abstract
The widespread use of mobile phones and social media platforms provides valuable information about users’ behavior and activities. Mobile phone data are rich on positional information, but lack semantic context. Conversely, geo-social media data reveal users’ opinions and activities, but are rather sparse [...] Read more.
The widespread use of mobile phones and social media platforms provides valuable information about users’ behavior and activities. Mobile phone data are rich on positional information, but lack semantic context. Conversely, geo-social media data reveal users’ opinions and activities, but are rather sparse in space and time. In the context of emergency management, both data types have been considered separately. To exploit their complementary nature and potential for emergency management, this paper introduces a novel methodology for improving situational awareness with the focus on urban events. For crowd detection, a spatial hot spot analysis of mobile phone data is used. The analysis of geo-social media data involves building spatio-temporal topic-sentiment clusters of posts. The results of the spatio-temporal contextual enrichment include unusual crowds associated with topics and sentiments derived from the analyzed geo-social media data. This methodology is demonstrated using the case study of the Vienna Pride. The results show how crowds change over time in terms of their location, size, topics discussed, and sentiments. Full article
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<p>Overview of the workflow and results.</p>
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<p>Georeferences of social media posts dated 17 June 2023, together with the areas for the location assignment.</p>
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<p>Visualization of clusters in <a href="#ijgi-13-00350-t002" class="html-table">Table 2</a>.</p>
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<p>Crowds detected around Rathausplatz at 1 PM on 17 June 2023, enriched with semantic and sentiment information gained from the analyzed geo-social media posts. The crowds are colored based on their sentiment: green for positive, yellow for neutral, red for negative, and gray for no sentiment.</p>
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<p>Crowds detected around Rathausplatz at 2 PM on 17 June 2023, enriched with semantic and sentiment information gained from the analyzed geo-social media posts.</p>
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<p>Hot spot analysis for 1 PM on 17 June 2023.</p>
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14 pages, 7836 KiB  
Review
Recent Progress in the Synthesis of 3D Complex Plasmonic Intragap Nanostructures and Their Applications in Surface-Enhanced Raman Scattering
by Li Ma, Keyi Zhou, Xinyue Wang, Jiayue Wang, Ruyu Zhao, Yifei Zhang and Fang Cheng
Biosensors 2024, 14(9), 433; https://doi.org/10.3390/bios14090433 - 6 Sep 2024
Viewed by 1477
Abstract
Plasmonic intragap nanostructures (PINs) have garnered intensive attention in Raman-related analysis due to their exceptional ability to enhance light–matter interactions. Although diverse synthetic strategies have been employed to create these nanostructures, the emphasis has largely been on PINs with simple configurations, which often [...] Read more.
Plasmonic intragap nanostructures (PINs) have garnered intensive attention in Raman-related analysis due to their exceptional ability to enhance light–matter interactions. Although diverse synthetic strategies have been employed to create these nanostructures, the emphasis has largely been on PINs with simple configurations, which often fall short in achieving effective near-field focusing. Three-dimensional (3D) complex PINs, distinguished by their intricate networks of internal gaps and voids, are emerging as superior structures for effective light trapping. These structures facilitate the generation of hot spots and hot zones that are essential for enhanced near-field focusing. Nevertheless, the synthesis techniques for these complex structures and their specific impacts on near-field focusing are not well-documented. This review discusses the recent advancements in the synthesis of 3D complex PINs and their applications in surface-enhanced Raman scattering (SERS). We begin by describing the foundational methods for fabricating simple PINs, followed by a discussion on the rational design strategies aimed at developing 3D complex PINs with superior near-field focusing capabilities. We also evaluate the SERS performance of various 3D complex PINs, emphasizing their advanced sensing capabilities. Lastly, we explore the future perspective of 3D complex PINs in SERS applications. Full article
(This article belongs to the Special Issue Functional Nanomaterials for Biosensing—2nd Edition)
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<p>Schematic illustration of synthetic strategies for 3D complex PINs from polyhedral nanocrystals.</p>
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<p>Structural transformation from 3D polyhedral nanocrystals to 3D nanoframes. (<b>A</b>) Synthesis of 3D Au nanosphere hexamer by a three-step method, with the corresponding products in each step. Copyright 2020 American Chemical Society [<a href="#B43-biosensors-14-00433" class="html-bibr">43</a>]. (<b>B</b>) Structural evolution from Ag nanocubes to AuAg cubic nanoframes. Copyright 2022 American Chemical Society [<a href="#B54-biosensors-14-00433" class="html-bibr">54</a>].</p>
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<p>Rational design of synthesis for 3D complex PINs by outer frame engineering of 3D nanoframes. (<b>A</b>) Au octahedral nanosponges. Copyright 2023 American Chemical Society [<a href="#B59-biosensors-14-00433" class="html-bibr">59</a>]. (<b>B</b>) Au dual frame-engraved nanoframes. Copyright 2022 Springer Nature [<a href="#B60-biosensors-14-00433" class="html-bibr">60</a>]. (<b>C</b>) AuAg all-frame-faceted tripod nanoframes. Copyright 2022 American Chemical Society [<a href="#B61-biosensors-14-00433" class="html-bibr">61</a>]. (<b>D</b>) AuAg nanosphere octamer. Copyright 2024 American Chemical Society [<a href="#B62-biosensors-14-00433" class="html-bibr">62</a>]. (<b>E</b>) Au cross-gap nanocubes. Copyright 2024 American Chemical Society [<a href="#B63-biosensors-14-00433" class="html-bibr">63</a>].</p>
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<p>Rational design of synthesis for 3D complex PINs by inner structure engineering of 3D nanoframes. (<b>A</b>) Au nanosphere heptamer. Copyright 2024 American Chemical Society [<a href="#B64-biosensors-14-00433" class="html-bibr">64</a>]. (<b>B</b>) Truncated-octahedral@octahedral PtAu dual nanoframes. Copyright 2023 Wiley-VCH GmbH [<a href="#B65-biosensors-14-00433" class="html-bibr">65</a>]. (<b>C</b>) Multi-layered Au nanoframes. Copyright 2022 Springer Nature [<a href="#B66-biosensors-14-00433" class="html-bibr">66</a>]. (<b>D</b>) Au octahedra@Au cubic nanoframes. Copyright 2024 American Chemical Society [<a href="#B67-biosensors-14-00433" class="html-bibr">67</a>]. (<b>E</b>) Multi-layered AuAg nanoframes. Copyright 2023 Wiley-VCH GmbH [<a href="#B68-biosensors-14-00433" class="html-bibr">68</a>].</p>
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<p>Single-particle SERS activity of 3D complex PINs. (<b>A</b>) Au nanosphere hexamer. (<b>a</b>) FEM calculations of near-field distribution. (<b>b</b>) Single-particle SERS measurements of Au nanosphere hexamer with different structures. (<b>c</b>) Reproducibility of single-particle SERS measurements. Copyright 2020 American Chemical Society [<a href="#B43-biosensors-14-00433" class="html-bibr">43</a>]. (<b>B</b>) Au nanosphere octamer. (<b>a</b>) Calculated near-field distributions. (<b>b</b>) Single-particle SERS measurements of Au nanosphere octamer with different structures. (<b>c</b>) Calculated enhancement factors. Copyright 2024 American Chemical Society [<a href="#B62-biosensors-14-00433" class="html-bibr">62</a>]. (<b>C</b>) Au octahedral nanosponges. (<b>a</b>) Calculated near-field distributions. (<b>b</b>) Single-particle SERS measurements of Au octahedral nanosponges with different structures. Copyright 2023 American Chemical Society [<a href="#B59-biosensors-14-00433" class="html-bibr">59</a>]. (<b>D</b>) Calculated near-field distributions of multi-layered nanoframes with different structures. Copyright 2022 Springer Nature [<a href="#B66-biosensors-14-00433" class="html-bibr">66</a>].</p>
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<p>Potential SERS applications using 3D complex PINs. (<b>A</b>) SERS detection using self-assembled 3D complex PINs. (<b>a</b>) SEM images of self-assembled monolayer of Au octahedral, Au cubic nanoframes, and Au octahedral@Au cubic nanoframes. (<b>b</b>) Calculated near-field distributions of Au octahedral, Au cubic nanoframes, and Au octahedral@Au cubic nanoframes. (<b>c</b>–<b>e</b>) Bulk SERS spectra from Au octahedral (<b>c</b>), Au cubic nanoframes (<b>d</b>), and Au octahedral@Au cubic nanoframes (<b>e</b>). Copyright 2024 American Chemical Society [<a href="#B67-biosensors-14-00433" class="html-bibr">67</a>]. (<b>B</b>) SERS detections of gas analytes using 3D complex PINs. (<b>a</b>) Schematic illustration for synthesis of an Au octahedral nanosponges@ZIF-8 film substrate. (<b>b</b>) Cross-section SEM images of SERS substrates with different thicknesses. (<b>c</b>) SERS spectra using different substrates. (<b>d</b>) SERS spectra using Au octahedral nanosponges@ZIF-8 substrate with different thicknesses. The characteristic peak of DMMP at 719 cm<sup>−1</sup> is marked as asterisk. Copyright 2023 American Chemical Society [<a href="#B59-biosensors-14-00433" class="html-bibr">59</a>]. (<b>C</b>) SERS immunoassay of HCG using 3D complex PINs. (<b>a</b>) Schematic illustration of SERS immunoassay of Au dual-rim nanoframes. (<b>b</b>,<b>c</b>) SERS spectra using 3D Au dual-rim nanoframes (<b>b</b>) and 2D Au triangular nanoframes (<b>c</b>) as probes. Copyright 2022 Springer Nature [<a href="#B60-biosensors-14-00433" class="html-bibr">60</a>].</p>
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24 pages, 8969 KiB  
Article
Analysis of Surface Water Area Changes and Driving Factors in the Tumen River Basin (China and North Korea) Using Google Earth Engine (2015–2023)
by Di Wu, Donghe Quan and Ri Jin
Water 2024, 16(15), 2185; https://doi.org/10.3390/w16152185 - 1 Aug 2024
Viewed by 1333
Abstract
Understanding the dynamics of water bodies is crucial for managing water resources and protecting ecosystems, especially in regions prone to climatic extremes. The Tumen River Basin, a transboundary area in Northeast Asia, has seen significant water body changes influenced by natural and anthropogenic [...] Read more.
Understanding the dynamics of water bodies is crucial for managing water resources and protecting ecosystems, especially in regions prone to climatic extremes. The Tumen River Basin, a transboundary area in Northeast Asia, has seen significant water body changes influenced by natural and anthropogenic factors. Using Landsat 8 and Sentinel-1 data on Google Earth Engine, we systematically analyzed the spatiotemporal variations and drivers of water body changes in this basin from 2015 to 2023. The water body extraction process demonstrated high accuracy, with overall precision rates of 95.75% for Landsat 8 and 98.25% for Sentinel-1. Despite observed annual fluctuations, the overall water area exhibited an increasing trend, notably peaking in 2016 due to an extraordinary flood event. Emerging Hot Spot Analysis revealed upstream areas as declining cold spots and downstream regions as increasing hot spots, with artificial water bodies showing a growth trend. Utilizing Random Forest Regression, key factors such as precipitation, potential evaporation, population density, bare land, and wetlands were identified, accounting for approximately 81.9–85.3% of the observed variations in the water body area. During the anomalous flood period from June to September 2016, the Geographically Weighted Regression (GWR) model underscored the predominant influence of precipitation, potential evaporation, and population density at the sub-basin scale. These findings provide critical insights for strategic water resource management and environmental conservation in the Tumen River Basin. Full article
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<p>Schematic map of the study area.</p>
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<p>Technical roadmap.</p>
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<p>Schematic diagram of different scale divisions. (<b>a</b>) Sub-basins. (<b>b</b>) Grid cells.</p>
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<p>Changes in the water area in the Tumen River Basin (2015–2023).</p>
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<p>(<b>a</b>) Hot–cold spot patterns, (<b>b</b>) hot–cold spot trends, and (<b>c</b>) water area hot–cold spot 3D in the Tumen River Basin at the sub-basins scale.</p>
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<p>(<b>a</b>) Hot–cold spot patterns, (<b>b</b>) hot–cold spot trends, and (<b>c</b>) water area hot–cold spot 3D in the Tumen River Basin at the grid scale.</p>
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<p>Relative importance of drivers of water area change at the (<b>a</b>) sub-basin and (<b>b</b>) grid scales.</p>
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<p>Partial dependence plots for the driving factors of water area changes at the sub-basin scale.</p>
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<p>Partial dependence plots for the driving factors of water area changes at the grid scale.</p>
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<p>Spatial distribution of the regression coefficients for different driving factors in relation to surface water area changes in 2016 at the sub-basin scale. (<b>a</b>) Precipitation from June to July. (<b>b</b>) Precipitation from July to August. (<b>c</b>) Precipitation from August to September. (<b>d</b>) Potential evapotranspiration from June to July. (<b>e</b>) Potential evapotranspiration from July to August. (<b>f</b>) Potential evapotranspiration from August to September. (<b>g</b>) Population density from June to July. (<b>h</b>) Population density from July to August. (<b>i</b>) Population density from August to September.</p>
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<p>Spatial distribution of the regression coefficients for different driving factors in relation to surface water area changes in 2016 at the grid scale. (<b>a</b>) Potential evapotranspiration from June to July. (<b>b</b>) Potential evapotranspiration from July to August. (<b>c</b>) Potential evapotranspiration from August to September. (<b>d</b>) Precipitation from June to July. (<b>e</b>) Precipitation from July to August. (<b>f</b>) Precipitation from August to September. (<b>g</b>) Population density from June to July. (<b>h</b>) Population density from July to August. (<b>i</b>) Population density from August to September.</p>
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26 pages, 7299 KiB  
Review
Global Bibliometric Analysis of Research on the Application of Unconventional Water in Agricultural Irrigation
by Peiwen Xu, Ziyi Jia, Huifeng Ning and Jinglei Wang
Water 2024, 16(12), 1698; https://doi.org/10.3390/w16121698 - 14 Jun 2024
Viewed by 1567
Abstract
The development and utilization of unconventional water resources has become a strategy to alleviate the agricultural water crisis in many countries and regions. To understand the research progress, hot spots, and future trends in the field of unconventional water agricultural irrigation (UWAI), this [...] Read more.
The development and utilization of unconventional water resources has become a strategy to alleviate the agricultural water crisis in many countries and regions. To understand the research progress, hot spots, and future trends in the field of unconventional water agricultural irrigation (UWAI), this paper systematically analyzes 6738 publications based on the core database of Web of Science 1990–2023 using the scientific bibliometric analysis software CiteSpace, VOSviewer, and Scimago Graphica. The results showed that the research on UWAI is always rapidly developing. Soil science, crop science, and bioengineering are the main disciplines involved. Most research on WUAI has occurred in China and the United States. Countries with higher levels of development tend to have more influence. Collaboration among authors is fragmented, and collaboration between authors and states needs to be strengthened. Through keyword analysis, the research hotspots are summarized as follows: (1) The effects of traditional and emerging pollutants brought by unconventional water irrigation on soil physicochemical properties, crop growth, and groundwater quality; (2) the health threats caused by pollutants entering the food chain and groundwater; (3) unconventional water utilization technologies, including rainwater harvesting agriculture, precision agriculture, and urban agriculture. Future research hotspots will focus on the mechanisms of pollutant solute transport and transformation in the water–soil–crop system under non-conventional water irrigation conditions and crop physiological responses. We suggest that the research on traditional and emerging pollutants in unconventional water should be strengthened in the future, and the risk control system of unconventional water irrigation should be improved. International cooperation should be strengthened, especially with poor countries in arid regions, to promote the formation of unified international standards and guidelines for non-conventional water irrigation in agriculture. Full article
(This article belongs to the Section Water, Agriculture and Aquaculture)
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<p>Study design flow chart of UWAI.</p>
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<p>The annual distribution of the UWAI publications and citations from 1990 to 2023.</p>
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<p>The dual-map overlay for publications related to UWAI using CiteSpace.</p>
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<p>Country/region collaboration map of UWAI using Scimago Graphica.</p>
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<p>Country/region collaboration map of UWAI using VOSviewer.</p>
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<p>Network visualization of cooperation among academic institutes using VOSviewer.</p>
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<p>Network visualization of cooperation among authors using CiteSpace.</p>
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<p>The cooperation relation graph of cited journals using VOSviewer.</p>
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<p>The keyword co-occurring network using CiteSpace.</p>
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<p>Keyword cluster analysis.</p>
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<p>Keyword bursts analysis.</p>
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34 pages, 22533 KiB  
Article
Interpretation of Hot Spots in Wuhan New Town Development and Analysis of Influencing Factors Based on Spatio-Temporal Pattern Mining
by Haijuan Zhao, Yan Long, Nina Wang, Shiqi Luo, Xi Liu, Tianyue Luo, Guoen Wang and Xuejun Liu
ISPRS Int. J. Geo-Inf. 2024, 13(6), 186; https://doi.org/10.3390/ijgi13060186 - 3 Jun 2024
Cited by 1 | Viewed by 1646
Abstract
The construction of new towns is one of the main measures to evacuate urban populations and promote regional coordination and urban–rural integration in China. Mining the spatio-temporal pattern of new town hot spots based on multivariate data and analyzing the influencing factors of [...] Read more.
The construction of new towns is one of the main measures to evacuate urban populations and promote regional coordination and urban–rural integration in China. Mining the spatio-temporal pattern of new town hot spots based on multivariate data and analyzing the influencing factors of new town construction hot spots can provide a strategic basis for new town construction, but few researchers have extracted and analyzed the influencing factors of new town internal hot spots and their classification. In order to define the key points of Wuhan’s new town construction and promote the construction of new cities in an orderly and efficient manner, this paper first constructs a space-time cube based on the luminous remote sensing data from 2010 to 2019, extracts hot spots and emerging hot spots in Wuhan New City, selects 14 influencing factor indicators such as population density, and uses bivariate Moran’s index to analyze the influencing factors of hot spots, indicating that the number of bus stops and vegetation coverage rate are the most significant. Secondly, the disorderly multivariate logistic regression model is used to analyze the influencing factors of emerging hot spots. The results show that population density, vegetation coverage, road density, distance to water bodies, and distance to train stations are the most significant factors. Finally, based on the analysis results, some relevant suggestions for the construction of Wuhan New City are proposed, providing theoretical support for the planning and policy guidance of new cities, and offering reference for the construction of new towns in other cities, promoting the construction of high-quality cities. Full article
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<p>Study area.</p>
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<p>Night-time light remote sensing masking results for Wuhan New City in 2019.</p>
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<p>(<b>a</b>) Remote sensing of night-time light emissions data and basic data for Wuhan New City in 2019 and (<b>b</b>) 2019 Wuhan New City POI data.</p>
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<p>Space-time cube model.</p>
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<p>Theory of emerging hot spot analysis.</p>
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<p>Influence factor indicators chart.</p>
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<p>Grid distribution of influencing factors indicators in 2019.</p>
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<p>Technical route.</p>
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<p>The results of space-time cube.</p>
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<p>Statistical chart of 10-year remote sensing data of night-time light emissions.</p>
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<p>Plane distribution map of emerging hot and cold spots.</p>
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<p>Cubic distribution map of emerging hot and cold spots.</p>
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<p>Scatter plot of positive factors’ Moran’s I.</p>
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<p>Scatter plot of negative factors’ Moran’s I.</p>
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<p>Wuhan New City spatial structure.</p>
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22 pages, 18976 KiB  
Article
Spatiotemporal Patterns of Air Pollutants over the Epidemic Course: A National Study in China
by Kun Qin, Zhanpeng Wang, Shaoqing Dai, Yuchen Li, Manyao Li, Chen Li, Ge Qiu, Yuanyuan Shi, Chun Yin, Shujuan Yang and Peng Jia
Remote Sens. 2024, 16(7), 1298; https://doi.org/10.3390/rs16071298 - 7 Apr 2024
Cited by 4 | Viewed by 2415
Abstract
Air pollution has been standing as one of the most pressing global challenges. The changing patterns of air pollutants at different spatial and temporal scales have been substantially studied all over the world, which, however, were intricately disturbed by COVID-19 and subsequent containment [...] Read more.
Air pollution has been standing as one of the most pressing global challenges. The changing patterns of air pollutants at different spatial and temporal scales have been substantially studied all over the world, which, however, were intricately disturbed by COVID-19 and subsequent containment measures. Understanding fine-scale changing patterns of air pollutants at different stages over the epidemic’s course is necessary for better identifying region-specific drivers of air pollution and preparing for environmental decision making during future epidemics. Taking China as an example, this study developed a multi-output LightGBM approach to estimate monthly concentrations of the six major air pollutants (i.e., PM2.5, PM10, NO2, SO2, O3, and CO) in China and revealed distinct spatiotemporal patterns for each pollutant over the epidemic’s course. The 5-year period of 2019–2023 was selected to observe changes in the concentrations of air pollutants from the pre-COVID-19 era to the lifting of all containment measures. The performance of our model, assessed by cross-validation R2, demonstrated high accuracy with values of 0.92 for PM2.5, 0.95 for PM10, 0.95 for O3, 0.90 for NO2, 0.79 for SO2, and 0.82 for CO. Notably, there was an improvement in the concentrations of particulate matter, particularly for PM2.5, although PM10 exhibited a rebound in northern regions. The concentrations of SO2 and CO consistently declined across the country over the epidemic’s course (p < 0.001 and p < 0.05, respectively), while O3 concentrations in southern regions experienced a notable increase. Concentrations of air pollutants in the Beijing–Tianjin–Hebei region were effectively controlled and mitigated. The findings of this study provide critical insights into changing trends of air quality during public health emergencies, help guide the development of targeted interventions, and inform policy making aimed at reducing disease burdens associated with air pollution. Full article
(This article belongs to the Special Issue Geographic Data Analysis and Modeling in Remote Sensing)
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<p>Spatial distribution of national automatic air quality monitoring stations in China.</p>
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<p>Flowchart of the modeling and analysis process for this study. LightGBM, light gradient boosting machine; MODIS, moderate resolution imaging spectroradiometer; TROPOMI, tropospheric monitoring instrument.</p>
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<p>Spatial distribution of annual mean concentration of PM<sub>2.5</sub> (<b>a</b>), PM<sub>10</sub> (<b>b</b>), NO<sub>2</sub> (<b>c</b>), SO<sub>2</sub> (<b>d</b>), O<sub>3</sub> (<b>e</b>), and CO (<b>f</b>) in China from 2019 to 2023. The unit is mg/m<sup>3</sup> for CO and µg/m<sup>3</sup> for other air pollutants.</p>
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<p>Spatial distribution of annual mean concentration of PM<sub>2.5</sub> (<b>a</b>), PM<sub>10</sub> (<b>b</b>), NO<sub>2</sub> (<b>c</b>), SO<sub>2</sub> (<b>d</b>), O<sub>3</sub> (<b>e</b>), and CO (<b>f</b>) in China from 2019 to 2023. The unit is mg/m<sup>3</sup> for CO and µg/m<sup>3</sup> for other air pollutants.</p>
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<p>Monthly mean concentrations of the six major air pollutants (<b>a</b>) and their interannual differences (<b>b</b>) in China from 2019 to 2023. The unit is mg/m<sup>3</sup> for CO and µg/m<sup>3</sup> for other air pollutants.</p>
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<p>Spatial distribution patterns (<b>left</b>) and the corresponding temporal trends (<b>right</b>) of air pollutants in China from 2019 to 2023, with <span class="html-italic">p</span>-values of the significant trends marked.</p>
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<p>Importance (%) of each feature during model construction.</p>
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<p>Density scatter plots of 10-fold cross-validation (CV) results of our multi-output LightGBM model. Solid lines denote the best-fit lines derived from linear regression, and dashed lines denote the 1:1 line. The provided information includes the sample size (N), coefficient of determination (R<sup>2</sup>), root-mean-square error (RMSE), and mean absolute error (MAE). The units of the RMSE and MAE are mg/m<sup>3</sup> for CO and µg/m<sup>3</sup> for other air pollutants.</p>
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<p>Density scatter plots of 10-fold cross-validation (CV) results of our multi-output LightGBM model. Solid lines denote the best-fit lines derived from linear regression, and dashed lines denote the 1:1 line. The provided information includes the sample size (N), coefficient of determination (R<sup>2</sup>), root-mean-square error (RMSE), and mean absolute error (MAE). The units of the RMSE and MAE are mg/m<sup>3</sup> for CO and µg/m<sup>3</sup> for other air pollutants.</p>
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<p>Spatial distributions of the site-based cross-validation results. RMSE, root-mean-square error. The units of the RMSE are mg/m<sup>3</sup> for CO and µg/m<sup>3</sup> for other air pollutants.</p>
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<p>Density scatter plots of yearly sample-based cross-validation (CV) results across China from 2019 to 2023. Solid lines denote the best-fit lines derived from linear regression, and dashed lines denote the 1:1 line. The provided information includes the sample size (N), coefficient of determination (R<sup>2</sup>), root-mean-square error (RMSE), and mean absolute error (MAE). The units of the RMSE and MAE are mg/m<sup>3</sup> for CO and µg/m<sup>3</sup> for other air pollutants. The pollutants from left to right are PM<sub>2.5</sub> (<b>a</b>), PM<sub>10</sub> (<b>b</b>), NO<sub>2</sub> (<b>c</b>), SO<sub>2</sub> (<b>d</b>), O<sub>3</sub> (<b>e</b>), and CO (<b>f</b>). Shown from top to bottom are the years 2019–2023 in order.</p>
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<p>Density scatter plots of yearly sample-based cross-validation (CV) results across China from 2019 to 2023. Solid lines denote the best-fit lines derived from linear regression, and dashed lines denote the 1:1 line. The provided information includes the sample size (N), coefficient of determination (R<sup>2</sup>), root-mean-square error (RMSE), and mean absolute error (MAE). The units of the RMSE and MAE are mg/m<sup>3</sup> for CO and µg/m<sup>3</sup> for other air pollutants. The pollutants from left to right are PM<sub>2.5</sub> (<b>a</b>), PM<sub>10</sub> (<b>b</b>), NO<sub>2</sub> (<b>c</b>), SO<sub>2</sub> (<b>d</b>), O<sub>3</sub> (<b>e</b>), and CO (<b>f</b>). Shown from top to bottom are the years 2019–2023 in order.</p>
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22 pages, 18845 KiB  
Article
Long-Term Dynamic Monitoring and Driving Force Analysis of Eco-Environmental Quality in China
by Weiwei Zhang, Zixi Liu, Kun Qin, Shaoqing Dai, Huiyuan Lu, Miao Lu, Jianwan Ji, Zhaohui Yang, Chao Chen and Peng Jia
Remote Sens. 2024, 16(6), 1028; https://doi.org/10.3390/rs16061028 - 14 Mar 2024
Cited by 4 | Viewed by 2059
Abstract
Accurate assessments of the historical and current status of eco-environmental quality (EEQ) are essential for governments to have a comprehensive understanding of regional ecological conditions, formulate scientific policies, and achieve the United Nations Sustainable Development Goals (SDGs). While various approaches to EEQ monitoring [...] Read more.
Accurate assessments of the historical and current status of eco-environmental quality (EEQ) are essential for governments to have a comprehensive understanding of regional ecological conditions, formulate scientific policies, and achieve the United Nations Sustainable Development Goals (SDGs). While various approaches to EEQ monitoring exist, they each have limitations and cannot be used universally. Moreover, previous studies lack detailed examinations of EEQ dynamics and its driving factors at national and local levels. Therefore, this study utilized a remote sensing ecological index (RSEI) to assess the EEQ of China from 2001 to 2021. Additionally, an emerging hot-spot analysis was conducted to study the spatial and temporal dynamics of the EEQ of China. The degree of influence of eight major drivers affecting EEQ was evaluated by a GeoDetector model. The results show that from 2001 to 2021, the mean RSEI values in China showed a fluctuating upward trend; the EEQ varied significantly in different regions of China, with a lower EEQ in the north and west and a higher EEQ in the northeast, east, and south in general. The spatio-temporal patterns of hot/cold spots in China were dominated by intensifying hot spots, persistent cold spots, and diminishing cold spots, with an area coverage of over 90%. The hot spots were concentrated to the east of the Hu Huanyong Line, while the cold spots were concentrated to its west. The oscillating hot/cold spots were located in the ecologically fragile agro-pastoral zone, next to the upper part of the Hu Huanyong Line. Natural forces have become the main driving force for changes in China’s EEQ, and precipitation and soil sand content were key variables affecting the EEQ. The interaction between these factors had a greater impact on the EEQ than individual factors. Full article
(This article belongs to the Special Issue Geographic Data Analysis and Modeling in Remote Sensing)
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<p>Basic characteristics of the study area.</p>
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<p>Technical flow chart of the study. EEQ, Eco-environmental quality; LST, Land Surface Temperature; NDBSI, Normalized Different Built-up and Soil Index; NDVI, Normalized Difference Vegetation Index; PCA, Principal Component Analysis; RSEI, Remote Sensing Ecological Index; WET, Wetness component of the tasseled cap transformation.</p>
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<p>Trends in the mean value of RSEI (Remote Sensing Ecological Index) in China, 2001–2021.</p>
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<p>Spatial distribution of RSEI (Remote Sensing Ecological Index) in China from 2001 to 2021.</p>
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<p>Example of annual change in the average value of RSEI (Remote Sensing Ecological Index) at the prefecture level from 2001 to 2021.</p>
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<p>Annual change in the average value of RSEI (Remote Sensing Ecological Index) at the provincial level from 2001 to 2021.</p>
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<p>The spatial-temporal patterns of RSEI (Remote Sensing Ecological Index) in China, 2001–2021.</p>
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<p>Driving factors of EEQ (Ecological Environmental Quality) in China, (<b>a</b>) elevation, (<b>b</b>) population density, (<b>c</b>) average annual temperature, (<b>d</b>) density of built-up area, (<b>e</b>) night-time light, (<b>f</b>) river network density, (<b>g</b>) average annual precipitation, (<b>h</b>) soil sand content. All drivers have been normalized in ArcGIS.</p>
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<p>Single-factor analysis. x1: elevation; x2: population density; x3: night-time light; x4: average annual precipitation; x5: soil sand content; x6: river network density; x7: average annual temperature; x8: density of built-up area. The <span class="html-italic">p</span>-values for all points are less than 0.001.</p>
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<p><span class="html-italic">q</span>-value of the extent to which the drivers affect the EEQ under the interaction. x1: elevation; x2: population density; x3: night-time light; x4: annual precipitation; x5: soil sand content; x6: river network density; x7: average annual temperature; x8: density of built-up area.</p>
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<p><span class="html-italic">q</span>-value of the extent to which the drivers affect the EEQ under the interaction. x1: elevation; x2: population density; x3: night-time light; x4: annual precipitation; x5: soil sand content; x6: river network density; x7: average annual temperature; x8: density of built-up area.</p>
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15 pages, 3439 KiB  
Article
Hot Spots of Gun Violence in the Era of Focused Deterrence: A Space-Time Analysis of Shootings in South Philadelphia
by Jamie Anne Boschan and Caterina G. Roman
Soc. Sci. 2024, 13(2), 119; https://doi.org/10.3390/socsci13020119 - 16 Feb 2024
Cited by 1 | Viewed by 2256
Abstract
Gun and street group violence remains a serious problem in cities across the United States and the focused deterrence strategy has been a widely applied law enforcement intervention to reduce it. Although two meta-analytical studies concluded that the intervention had a significant effect [...] Read more.
Gun and street group violence remains a serious problem in cities across the United States and the focused deterrence strategy has been a widely applied law enforcement intervention to reduce it. Although two meta-analytical studies concluded that the intervention had a significant effect on violence, questions remain about how violence changes across space and time during and after the intervention. This study applies novel geospatial analyses to assess spatiotemporal changes in gun violence before, during, and after the implementation of Philadelphia Focused Deterrence. Emerging hot spot analysis employing Space-Time cubes of ten annual time bins (2009–2018) at the Thiessen polygon level was used to detect and categorize patterns. The analyses revealed a non-significant decreasing trend across the ten-year period. Furthermore, there were ninety-three statistically significant hot spots categorized into four hot spot patterns: fourteen new hot spots; twenty-three consecutive; one persistent; and fifty-three sporadic. There was no evidence showing statistically significant hot spots for the “diminishing” pattern. Knowledge of these patterns that emerge across micro-locations can be used by law enforcement practitioners to complement data-driven problem solving and fine tune these strategies and other place-based programming. Policymakers can use findings to prioritize resources when developing complementary prevention and intervention efforts by tailoring those efforts to the different emergent patterns. Full article
(This article belongs to the Section Community and Urban Sociology)
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<p>The focused deterrence intervention area, Philadelphia, PA.</p>
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<p>Mean of shooting victims in Thiessen polygons, South Philadelphia, PA, 2009 to 2018.</p>
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<p>Results of optimized hot spot analysis comparing focused deterrence pre-intervention and post-intervention periods, South Philadelphia, PA. (<b>a</b>) shows the pre-intervention period (2009–2011); (<b>b</b>) shows the post-intervention period (2015–2017).</p>
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<p>Emerging hot spot analysis using Thiessen polygons, South Philadelphia, PA. (Panel (<b>a</b>) shows the full view; panel (<b>b</b>) shows the zoomed-in view).</p>
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