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26 pages, 5315 KiB  
Article
Biomimicry-Based Design of Underground Cold Storage Facilities: Energy Efficiency and Sustainability
by Mugdha Kshirsagar, Sanjay Kulkarni, Ankush Kumar Meena, Danby Caetano D’costa, Aroushi Bhagwat, Md Irfanul Haque Siddiqui and Dan Dobrotă
Biomimetics 2025, 10(2), 122; https://doi.org/10.3390/biomimetics10020122 - 18 Feb 2025
Viewed by 168
Abstract
Underground cold storage gives rise to special challenges that require innovative solutions to ensure maximum energy efficiency. Conventional energy systems tend to be based on high energy use, so sustainable solutions are crucial. This study explores the novel idea of biomimetics and how [...] Read more.
Underground cold storage gives rise to special challenges that require innovative solutions to ensure maximum energy efficiency. Conventional energy systems tend to be based on high energy use, so sustainable solutions are crucial. This study explores the novel idea of biomimetics and how it might be used in the planning and building of underground cold storage facilities as well as other infrastructure projects. Biomimetic strategies, inspired by termite mounds, gentoo penguin feathers, and beehive structures, are applied to minimize reliance on energy-intensive cooling systems. These natural models offer efficient thermal regulation, airflow optimization, and passive cooling mechanisms such as geothermal energy harvesting. The integration of naturally driven convection and ventilation ensures stable internal temperatures under varying conditions. Biomimicry was employed in Revit Architecture, coupled with structural optimization, to eliminate urban space’s limitations and further increase energy efficiency. The analytical work for this paper utilized a set of formulas that represent heat flow, thermal resistance, R-value, thermal transmittance, U-value, solar absorption, and G-value. The results pointed to very good insulation, with exterior walls having an R-value of 10.2 m2K/W and U-value of 0.98 W/m2K. Among the chosen 3-layer ETFE cushion with a U-value of 1.96 W/m2K, with a G-value of 0.50, showed good heat regulation and daylight management. Furthermore, bagasse-cement composites with a very low thermal conductivity of 0.10–0.30 W/m·K provided good insulation. This research proposes a scalable and sustainable approach in the design of underground cold storage by merging modelling based on Revit with thermal simulations. Biomimicry has been demonstrated to have the potential for changing subterranean infrastructure, conserving energy consumption, and creating eco-friendly construction practices. Full article
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<p>Methodology Flowchart.</p>
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<p>Dimensions of the proposed storage boxes.</p>
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<p>Iceberg concept implemented for the cold storage facility with (90:10) underground-to-above-ground ratio (made using Revit).</p>
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<p>ETFE roofing in a research building in Braunschweig, Germany. Source: <a href="https://specialtyfabricsreview.com/wp-content/uploads/sites/28/2018/03/6907_20171222_1N4V9587_1_Hanno-Keppel.jpg" target="_blank">https://specialtyfabricsreview.com/wp-content/uploads/sites/28/2018/03/6907_20171222_1N4V9587_1_Hanno-Keppel.jpg</a> (accessed on 1 December 2024). Photos: Hanno Keppel.</p>
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<p>3-layer ETFE cushion system implemented in the surface warehouse facility (made using Revit).</p>
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<p>Body structure of a Gentoo penguin.</p>
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<p>Cross-section of the exterior wall of subsurface cold storage facility showing the layers of insulation.</p>
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<p>Induced flow model for termite mound ventilation.</p>
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<p>Schematic Drawing of ventilator hoods.</p>
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<p>Structure A: Bagasse-Cement Composite Wall.</p>
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<p>Structure B: Common insulating wall.</p>
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<p>Structure C: Regular masonry wall.</p>
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<p>Spread of forces on a hexagon cell.</p>
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<p>Difference between regular and non-regular tessellating patterns.</p>
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22 pages, 5027 KiB  
Essay
Analysis of Water Source Conservation Driving Factors Based on Machine Learning
by Yixuan Jia, Zhe Zhang, Chunhua Huang and Shuibo Xie
Sustainability 2025, 17(4), 1713; https://doi.org/10.3390/su17041713 - 18 Feb 2025
Viewed by 75
Abstract
This study focuses on the spatiotemporal dynamic changes in water retention capacity and the nonlinear research of its influencing factors. By using the InVEST model, the changing trends of water retention capacity in different regions and at various time scales were analyzed. Based [...] Read more.
This study focuses on the spatiotemporal dynamic changes in water retention capacity and the nonlinear research of its influencing factors. By using the InVEST model, the changing trends of water retention capacity in different regions and at various time scales were analyzed. Based on this, the results were further examined using the CatBoost model with SHAP (SHapley Additive exPlanations) analysis and PDP (Partial Dependence Plot) analysis. The results show the following: (1) From 2003 to 2023, the water conservation capacity first increased and then decreased, and spatially, the water conservation capacity of the mountainous area in the west of the Yiluo River Basin and Xionger Mountain in the middle part of the basin increased as a whole. At the same time, the forest land in the basin contributed more than 60% of the water conservation capacity. (2) Precipitation is the most significant driving factor for water conservation in the basin, and plant water content, soil type, and temperature are also the main driving factors for water conservation in the Yiluo River Basin. (3) The interaction between temperature and other influencing factors can significantly improve water conservation. This research not only provides scientific evidence for understanding the driving mechanisms of water conservation but also offers references for water resource management and ecological protection planning. Full article
21 pages, 5548 KiB  
Article
Spatiotemporal Dynamics of Ilex macrocarpa Distribution Under Future Climate Scenarios: Implications for Conservation Planning
by Ying Liu, Qiong Yang, Suhang Li, Yawen Zhang, Yangzhou Xiang, Yan Yang and Jinxin Zhang
Forests 2025, 16(2), 370; https://doi.org/10.3390/f16020370 - 18 Feb 2025
Viewed by 124
Abstract
Identifying ecological distribution responses to climate change is pivotal for preserving biodiversity. Ilex macrocarpa, a deciduous tree of the Aquifoliaceae family, has considerable ecological and medicinal benefits. This study investigated the impact of climate change on the potential distribution of I. macrocarpa [...] Read more.
Identifying ecological distribution responses to climate change is pivotal for preserving biodiversity. Ilex macrocarpa, a deciduous tree of the Aquifoliaceae family, has considerable ecological and medicinal benefits. This study investigated the impact of climate change on the potential distribution of I. macrocarpa using MaxEnt modeling and GIS analysis. We analyzed 562 occurrence records against 19 bioclimatic variables, subsequently refined to 7 key predictors through Pearson correlation analysis (|r| ≤ 0.75). The MaxEnt model demonstrated high predictive accuracy (AUC = 0.902 ± 0.010). Annual precipitation (67.9% contribution) and the minimum temperature of the coldest month (18.4% contribution) emerged as the primary determinants of I. macrocarpa distribution. Currently, suitable habitats occupy 252.97 × 104 km2 (26.35%) of the total land area of China, with highly suitable areas (72.82 × 104 km2) predominantly found in southern China. Under future scenarios, substantial distribution shifts are projected: SSP126 shows a 21.7% reduction in suitable area by 2050, followed by a 9.1% recovery by 2090; SSP245 indicates a 13.4% reduction by 2050 with minimal subsequent change; and SSP585 demonstrates the most severe impact, with a 32.0% reduction by 2090. Habitat centroid analysis reveals significant northeastward shifts under SSP126 (116.23 km by 2090), variable movements under SSP245, and southwestern displacement under SSP585 (143.23 km by 2090). These findings suggest differential responses across climate scenarios, with implications for conservation planning and management strategies. Full article
(This article belongs to the Section Forest Meteorology and Climate Change)
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<p>Current distribution information and photos of <span class="html-italic">I. macrocarpa</span> in China. (<b>a</b>) Occurrence records; (<b>b</b>) leaves and fruits; (<b>c</b>) whole tree.</p>
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<p>Pearson correlation analysis involving 19 environmental factors.</p>
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<p>Verification of the MaxEnt model for predicting the distribution of <span class="html-italic">I. macrocarpa</span>: (<b>a</b>) omission rate and (<b>b</b>) ROC response curve from 10 simulation runs.</p>
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<p>Contribution (<b>a</b>) and jackknife evaluation of regularized training gain (<b>b</b>) of environmental variables associated with <span class="html-italic">I. macrocarpa</span> via MaxEnt.</p>
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<p>Curves for the presence probability of <span class="html-italic">I. macrocarpa</span> in response to variables. The red lines indicate the mean from 10 replicate trials; blue intervals depict the standard deviation (SD) across 10 replicates; horizontal green solid lines highlight the optimal suitable range.</p>
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<p>Geographic occurrence of favorable habitats for <span class="html-italic">I. macrocarpa</span> under the present climate conditions.</p>
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<p>Future climate-driven distribution projections for <span class="html-italic">I. macrocarpa</span>.</p>
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<p>Variations in the spatial and geographical distribution of total suitable habitat across future climate scenarios relative to the present.</p>
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<p>Shift in the centroid of the suitable habitat for <span class="html-italic">I. macrocarpa</span> under varying climate scenarios.</p>
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20 pages, 3386 KiB  
Article
Spatial Synergy Between Cultural Heritage and Metro Networks: A Case Study of Distribution Patterns and Value Assessment in Beijing
by Haisheng Hu
Sustainability 2025, 17(4), 1666; https://doi.org/10.3390/su17041666 - 17 Feb 2025
Viewed by 155
Abstract
With the rapid advancement of urbanisation and transit networks, exploring the spatial relationship between metro systems and cultural heritage is crucial for both heritage preservation and sustainable urban development. This study uses the nearest neighbour index, kernel density analysis, and spatial value evaluation [...] Read more.
With the rapid advancement of urbanisation and transit networks, exploring the spatial relationship between metro systems and cultural heritage is crucial for both heritage preservation and sustainable urban development. This study uses the nearest neighbour index, kernel density analysis, and spatial value evaluation to examine the distribution patterns of cultural heritage in Beijing and its spatial interaction with the metro network. The results show that different types of cultural heritage have distinct distribution characteristics: stone inscriptions are widely dispersed due to their need for preservation in natural settings; traditional villages and ancient tombs are shaped by historical and geographical factors; and industrial heritage is concentrated in areas of historical industrial activity, reflecting strong functional zoning traits. The metro network enhances the accessibility of cultural heritage, especially national- and provincial-level sites, which are predominantly clustered near metro stations. However, geographically isolated world heritage sites, such as the Great Wall and the Ming Tombs, remain less connected to the metro network, helping preserve their authenticity and avoid overdevelopment. Furthermore, thematic designs and cultural displays within Beijing’s metro stations successfully bridge the gap between history and modernity, positioning metro stations as key platforms for cultural dissemination. Nevertheless, metro construction presents challenges to heritage conservation, including potential impacts on site stability due to tunnelling and conflicts between modern station design and the aesthetic integrity of historic districts. These findings offer practical insights for cultural heritage preservation and transit planning in Beijing and serve as a reference for the sustainable development of other historic cities worldwide. Full article
(This article belongs to the Section Tourism, Culture, and Heritage)
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<p>Research flow chart.</p>
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<p>Distribution of metro stations and cultural heritage sites in Beijing: (<b>A</b>) Spatial kernel density distribution of metro stations in Beijing; (<b>B</b>) Spatial kernel density distribution of world-level heritage sites in Beijing; (<b>C</b>) Spatial kernel density distribution of national-level heritage sites in Beijing; (<b>D</b>) Spatial kernel density distribution of municipal-level heritage sites in Beijing; (<b>E</b>) Relative spatial relationship between cultural heritage sites and the metro network in Beijing; (<b>F</b>) Statistical analysis of distances between cultural heritage sites and the nearest metro station.</p>
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<p>Distribution of cultural heritage sites along Beijing metro lines. The background colour blocks represent the density distribution of points of interest (POIs). POIs include three categories of facilities: food and beverage, hotel and accommodation, and shopping and consumption.</p>
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<p>Statistical analysis of cultural heritage sites’ scores within 1 km of major metro lines in Beijing: (<b>A</b>) Total scores and ranks. (<b>B</b>) Score proportions of both Important Historical Sites and Representative Buildings of Modern Times and Ancient Buildings and Architecture. Score ranks of (<b>C</b>) Important Historical Sites and Representative Buildings of Modern Times and (<b>D</b>) Ancient Buildings and Architecture. (<b>E</b>) The proportion of different categories of cultural heritage sites along various metro lines.</p>
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<p>Correlation between metro networks, cultural heritage distribution, and regional infrastructure: (<b>A</b>) Spearman correlation between the number of metro stations and three categories of facilities—food and beverage, hotel and accommodation, and shopping and consumption—within a 1 km radius of cultural heritage sites in Beijing. (<b>B</b>) Relationship between the number of metro stations and the density of food and beverage, hotel and accommodation, and shopping and consumption facilities within a 1 km radius of cultural heritage sites in Beijing. (<b>C</b>) Cultural heritage tourism recommendations based on cultural heritage value assessment, metro accessibility, and the distribution of food, accommodation, and shopping facilities. The base map sourced from Google Maps, with location labels in both Chinese and English. (<b>D</b>) Division of cultural districts in Beijing [<a href="#B37-sustainability-17-01666" class="html-bibr">37</a>].</p>
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<p>Trends in the interaction between Beijing’s cultural heritage districts and the metro. Source: Beijing Urban Master Plan (2016–2035)—Schematic Plan for Municipal Rail Transit 2023).</p>
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<p>Schematic diagram of the cultural display of underground space in three typical metro stations.</p>
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29 pages, 6598 KiB  
Article
Relationships and Spatiotemporal Variations of Ecosystem Services and Land Use in Alpine Ecosystems: A Case Study of the Daxing’anling Forest Area, Inner Mongolia
by Laixian Xu, Youjun He, Liang Zhang, Chunwei Tang and Hui Xu
Forests 2025, 16(2), 359; https://doi.org/10.3390/f16020359 - 17 Feb 2025
Viewed by 130
Abstract
Quantifying the dynamic changes and relationships between ecosystem services (ESs) and land use change is critical for sustainable ecosystem management and land use optimization. However, comprehensive discussions on the spatiotemporal variations of ESs and their relationships with land use intensity (LUI) are lacking, [...] Read more.
Quantifying the dynamic changes and relationships between ecosystem services (ESs) and land use change is critical for sustainable ecosystem management and land use optimization. However, comprehensive discussions on the spatiotemporal variations of ESs and their relationships with land use intensity (LUI) are lacking, particularly in the context of significant climate warming. Systematic analyses of the forestry management unit scale are limited, leading to considerable uncertainty in sustainable ecosystem management, especially in alpine ecosystems of the Northern Hemisphere, where ESs have significantly degraded. The study focuses on the Daxing’anling forest area, Inner Mongolia (DFIAM), a representative sensitive alpine ecosystem and crucial ecological security barrier in Northern China. Utilizing the InVEST model, we analyzed the spatiotemporal variations in land use and four essential ESs, water yield (WY), carbon storage (CS), soil conservation (SC), and habitat quality (HQ), from 2013 to 2018. We also assessed the dynamic relationships between LUI and these ESs using a four-quadrant model. Our findings indicate the following: (1) Land use types in DFIAM remained relatively stable between 2013 and 2018, with forest being the dominant type (approximately 93%). During this period, areas of forest, cropland, impervious surfaces, and bare land increased, while areas of grassland, water, and wetland decreased. Although the overall change of LUI was gentle, a spatial pattern of “high in the southeast and low in the northwest” emerged, with low LUI areas showing slight expansion. (2) WY, SC, and HQ decreased, while CS increased from 2013 to 2018. The spatial distributions of these ESs showed higher values in the center and lower values at the edges, with forests demonstrating a strong capacity to provide multiple ESs. (3) The relationship between LUI and the four ESs from 2013 to 2018 was predominantly negative, primarily situated in Quadrant II, indicating that increased LUI inhibited ES supply capacity. Within Quadrant II, the distribution range of LUI, WY, and HQ decreased, while CS remained stable and SC increased. Furthermore, Quadrant III (positive correlation) accounted for a large proportion (19.23%~42.31%), highlighting the important role of non-anthropogenic factors in ES changes. Overall, most ESs in the DFAIM showed a decline while LUI remained relatively stable, with predominantly negative correlations between LUI and ESs. The increased LUI driven by human activities, and other non-human factors, may have contributed significantly to ES degradation. To improve ESs, we proposed implementing differentiated land use planning and management, systematic ecological protection and restoration strategies, a multi-level ecological early-warning monitoring and evaluation network, ecological corridors and buffer zones, and a collaborative management system with multiple participation. These results provide scientific guidance for the sustainable management of alpine ecosystems, enhancement of ESs, and formulation of land resource protection policies. Full article
(This article belongs to the Section Forest Ecology and Management)
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<p>Map of the study area.</p>
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<p>Spatial distribution of DFAIM land use in 2013 (<b>a</b>) and 2018 (<b>b</b>), and land use transfer change (<b>c</b>) from 2013 to 2018.</p>
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<p>LUI and changes in DFAIM from 2013 to 2018.</p>
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<p>Supply capacity of individual ESs for different land use types in DFAIM from 2013 to 2018. WY, CS, SC, and HQ are short for water yield, carbon storage, soil conservation, and habitat quality, respectively. Same below.</p>
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<p>ESCI of different land use types in DFAIM. ESCI stands for ecosystem service change index.</p>
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<p>Spatial distribution of ESs in DFAIM for the years 2013 (<b>a</b>,<b>d</b>,<b>g</b>,<b>j</b>) and 2018 (<b>b</b>,<b>e</b>,<b>h</b>,<b>k</b>) and the difference between the two years (<b>c</b>,<b>f</b>,<b>i</b>,<b>l</b>).</p>
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<p>The supply capacity levels of various ESs of DFAIM in 2013 and 2018.</p>
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<p>Relationship between LUI and individual ESs in 2013 and 2018. I represents Quadrant I; II represents Quadrant II; III represents Quadrant III; and IV represents Quadrant IV.</p>
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18 pages, 16515 KiB  
Article
Microalgal Diversity as Bioindicators for Assessing and Sustaining Water Quality in the High Mountain Lakes of Quimsacocha, Azuay, Ecuador
by Ernesto Delgado-Fernández, Darío Cruz, Rubén Ayavaca, Ángel Benítez and Bolívar Hernández
Sustainability 2025, 17(4), 1620; https://doi.org/10.3390/su17041620 - 15 Feb 2025
Viewed by 309
Abstract
Phytoplankton has an essential role as a primary producer in lakes, providing information on environmental conditions and water quality. The objective of this research was to inventory, characterize, and assess the diversity of microalgae in the Quimsacocha lake system in Azuay, Ecuador. Water [...] Read more.
Phytoplankton has an essential role as a primary producer in lakes, providing information on environmental conditions and water quality. The objective of this research was to inventory, characterize, and assess the diversity of microalgae in the Quimsacocha lake system in Azuay, Ecuador. Water samples were collected from the two most important Quimsacocha lakes to morphologically characterize the microalgae and evaluate their diversity. The diversity and physicochemical parameters were measured to evaluate and explain differences in community richness and composition using multivariate analysis (NMDS and PERMANOVA). The level of organic pollution in the lakes was estimated using the Pollution Index, and the trophic status was assessed using dominant phytoplankton (AARL-PP Score). Eighty morphospecies were identified within 25 genera, 16 families and 8 classes. The Bacillariophyceae class was the most diverse, represented by five families. The genera Synedra, Chlorella, and Cosmarium were the most abundant, suggesting a moderate level of organic pollution and a mesotrophic state in the lakes. Physicochemical parameters such as temperature, pH, dissolved oxygen and electrical conductivity were similar in both lakes. Nonetheless, the lake depth was different, varying between 0.9 and 8 m in LQA (with one extreme value of 22 m), compared to LQB, which had depths between 7 and 19 m. Alpha diversity revealed a significant difference (p = 0.0001) in species abundance between the two lakes, while specific richness was similar (p = 0.8213). In terms of beta diversity, a significant difference in species composition was observed (p = 0.001). This study provides base-line information regarding the ecological status of these Andean lakes, being of great help in developing conservation plans to preserve their biodiversity and water quality for human consumption. Full article
(This article belongs to the Section Sustainability, Biodiversity and Conservation)
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<p>Sampling stations within the study area of the lakes LQA (upper left) and LQB (lower right). The green dots indicate locations where the sampling and measurement of physicochemical parameters were carried out.</p>
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<p>Quick visual guide for the most relevant microalgae found. (<b>A</b>,<b>B</b>) <span class="html-italic">Arthrodesmus</span> sp. (<b>C</b>) <span class="html-italic">Botryococcus</span> sp. (<b>D</b>–<b>F</b>) <span class="html-italic">Cosmarium</span> sp. (<b>G</b>) <span class="html-italic">Cymbopleura</span> sp. (<b>H</b>) <span class="html-italic">Dinobryon</span> sp. (<b>I</b>) <span class="html-italic">Euglena</span> sp. (<b>J</b>) <span class="html-italic">Fragilaria</span> sp. (<b>K</b>); <span class="html-italic">Mougeotia</span> sp. (<b>L</b>) <span class="html-italic">Navicula</span> sp. (<b>M</b>) <span class="html-italic">Oocystis</span> sp (<b>N</b>) <span class="html-italic">Staurodesmus</span> sp. (<b>O</b>) <span class="html-italic">Staurastrum</span> sp. (<b>P</b>–<b>R</b>) Synedra sp. (<b>S</b>) <span class="html-italic">Tabellaria</span> sp. (<b>T</b>) <span class="html-italic">Trebouxia</span> sp. Scale bars represent: A, B, D, E, K, L, M, N &amp; T, 5 μm; C, F, G, H, I, J, O, P, Q &amp; R, 10 μm; S, 20 μm.</p>
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<p>Dominant genera of microalgae for LQA-LQB. The three most abundant microalgae genera found are shown: <span class="html-italic">Synedra, Cholorella</span> and <span class="html-italic">Cosmarium</span>.</p>
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<p>Microalgae species accumulation curve. The stabilization of the curves indicates that the sampling is suitable, which would represent a large proportion of the species richness.</p>
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<p>Box-and-whisker plot for microalgae richness and abundance.</p>
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<p>Graphical representation of the similarity of microalgal communities between LQA and LQB, based on the NMDS analysis. Each point in the figure represents a sampling point and its position in space is determined by its similarity in relation to other points.</p>
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10 pages, 213 KiB  
Communication
How Do Tourism and Environmental Theories Intersect?
by Angeliki N. Menegaki
Tour. Hosp. 2025, 6(1), 28; https://doi.org/10.3390/tourhosp6010028 - 14 Feb 2025
Viewed by 298
Abstract
This paper explores the intersection of tourism and environmental theories, highlighting how sustainability serves as a critical bridge between the two disciplines. Tourism theories such as Butler’s Tourism Area Life Cycle (TALC) and the Theory of Planned Behavior (TPB) provide insights into destination [...] Read more.
This paper explores the intersection of tourism and environmental theories, highlighting how sustainability serves as a critical bridge between the two disciplines. Tourism theories such as Butler’s Tourism Area Life Cycle (TALC) and the Theory of Planned Behavior (TPB) provide insights into destination development and tourist behavior but often lack an ecological perspective. The environmental framework, including Ecological Modernization Theory (EMT) and Common-Pool Resource (CPR) Theory, emphasizes sustainable resource management and the interconnectedness of human activities and natural systems. This paper examines common concepts such as carrying capacity, sustainable development, and behavioral insights while also identifying tensions between economic growth and environmental preservation. Case studies from Costa Rica, Hawaii, and Thailand illustrate practical applications of these theories in real-world settings, revealing how tourism can be both a threat and a tool for conservation. My paper concludes that integrating environmental impact assessment (EIA) and community-based tourism (CBT) models into tourism planning can lead to better long-term resource management. It recommends the adoption of stricter regulations on tourism development in fragile ecosystems, the implementation of eco-certifications, and the promotion of locally governed tourism initiatives. These strategies will ensure the sustainability of both tourism activities and the ecosystems on which they depend. Full article
38 pages, 5798 KiB  
Article
Research on the Social Values of Vehicle–Road Collaborative Intelligence Systems: A Case Study in Beijing
by Guangyu Zhu, Fuquan Zhao, Haokun Song, Wang Zhang and Zongwei Liu
Sustainability 2025, 17(4), 1565; https://doi.org/10.3390/su17041565 - 13 Feb 2025
Viewed by 530
Abstract
Intelligent vehicles are expected to yield significant benefits in traffic safety, traffic efficiency, energy conservation, and carbon emission reduction. As the collaborative intelligence technology route becomes an industry consensus, intelligent vehicles will generate greater social benefits under the empowerment of roadside intelligence infrastructure. [...] Read more.
Intelligent vehicles are expected to yield significant benefits in traffic safety, traffic efficiency, energy conservation, and carbon emission reduction. As the collaborative intelligence technology route becomes an industry consensus, intelligent vehicles will generate greater social benefits under the empowerment of roadside intelligence infrastructure. At the same time, the introduction of roadside intelligence infrastructure also adds corresponding deployment costs and operation and maintenance costs. Currently, assessments of the comprehensive social benefits and cost inputs associated with the application of vehicle–road collaborative intelligence systems remain unclear, making it difficult to provide effective references for industry development. Therefore, it is necessary to conduct a comprehensive assessment of the multi-dimensional benefits generated by collaborative intelligence systems and the incremental costs. This study constructs a social value assessment model for vehicle–road collaborative intelligence systems, which includes three benefit sub-models for safety, efficiency, and carbon emission reduction, as well as two cost sub-models for vehicle-side networking and roadside intelligence infrastructure. Beijing is selected for case analysis. The social benefits and social incremental cost inputs of different intelligence deployment scenarios are scientifically evaluated and analyzed. The study indicates that by deploying roadside intelligence infrastructure and in-vehicle networking terminals as planned in Beijing, an accumulated safety benefit of 925.6 billion RMB, a traffic efficiency benefit of 628.9 billion RMB, and a carbon emission reduction benefit of 2.66 billion RMB are expected to be generated from 2024 to 2050. The cumulative cost investment of 28.8 billion RMB in roadside intelligence infrastructure and vehicle networking terminals is projected to yield approximately 20.8 times the increment in social comprehensive benefits. The deployment progress of roadside intelligence infrastructure and the loading progress of fleet networking terminals should be fully coordinated to maximize the social value of the system. The corresponding research findings can provide references for city managers in decision-making on intelligent road deployment, and for the coordination of vehicle manufacturers in equipping vehicle networking terminals. Full article
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<p>Social value evaluation model of vehicle–road collaborative intelligence system.</p>
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<p>Typical perception schemes of ICVs [<a href="#B28-sustainability-17-01565" class="html-bibr">28</a>].</p>
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<p>Perception schemes of roadside intelligence [<a href="#B29-sustainability-17-01565" class="html-bibr">29</a>].</p>
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<p>Forecast of vehicle ownership in Beijing.</p>
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<p>Analysis framework for traffic operation safety benefits.</p>
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<p>Forecast of amount of traffic accidents in 2025–2050 (baseline scenario).</p>
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<p>Multivariable coupling model of intelligent vehicle safety effects.</p>
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<p>Reduction in fatal accidents in various vehicle–road intelligence deployment scenarios.</p>
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<p>Analysis framework for traffic efficiency benefit.</p>
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<p>Sub-model of traffic efficiency impact assessment.</p>
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<p>Sub-model of carbon emission reduction benefit.</p>
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<p>Deployment cost and energy consumption cost of roadside intellectualization. (<b>a</b>) Deployment cost, (<b>b</b>) energy consumption cost.</p>
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<p>Safety benefits under various intelligence scenarios from 2025 to 2050.</p>
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<p>Traffic efficiency benefits under various intelligence scenarios from 2025 to 2050.</p>
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<p>Carbon emission reduction benefits under various intelligence scenarios from 2025 to 2050.</p>
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<p>Annual incremental cost of roadside intelligence infrastructure. (<b>a</b>) APIR, (<b>b</b>) RPIR.</p>
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<p>Cumulative cost of roadside intelligence infrastructure (2024–2050).</p>
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<p>Annual incremental cost of vehicle-side networking. (<b>a</b>) LCV, (<b>b</b>) APCV.</p>
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<p>Social values of various intelligence scenarios.</p>
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30 pages, 7566 KiB  
Article
One Health Approach to the Computational Design of a Lipoprotein-Based Multi-Epitope Vaccine Against Human and Livestock Tuberculosis
by Robert Adamu Shey, Gordon Takop Nchanji, Tangan Yanick Aqua Stong, Ntang Emmaculate Yaah, Cabirou Mounchili Shintouo, Bernis Neneyoh Yengo, Derrick Neba Nebangwa, Mary Teke Efeti, Joan Amban Chick, Abey Blessings Ayuk, Ketura Yaje Gwei, Arnaud Azonpi Lemoge, Luc Vanhamme, Stephen Mbigha Ghogomu and Jacob Souopgui
Int. J. Mol. Sci. 2025, 26(4), 1587; https://doi.org/10.3390/ijms26041587 - 13 Feb 2025
Viewed by 301
Abstract
Tuberculosis (TB) remains a major cause of ill health and one of the leading causes of death worldwide, with about 1.25 million deaths estimated in 2023. Control measures have focused principally on early diagnosis, the treatment of active TB, and vaccination. However, the [...] Read more.
Tuberculosis (TB) remains a major cause of ill health and one of the leading causes of death worldwide, with about 1.25 million deaths estimated in 2023. Control measures have focused principally on early diagnosis, the treatment of active TB, and vaccination. However, the widespread emergence of anti-tuberculosis drug resistance remains the major public health threat to progress made in global TB care and control. Moreover, the Bacillus Calmette–Guérin (BCG) vaccine, the only licensed vaccine against TB in children, has been in use for over a century, and there have been considerable debates concerning its effectiveness in TB control. A multi-epitope vaccine against TB would be an invaluable tool to attain the Global Plan to End TB 2023–2030 target. A rational approach that combines several B-cell and T-cell epitopes from key lipoproteins was adopted to design a novel multi-epitope vaccine candidate. In addition, interactions with TLR4 were implemented to assess its ability to elicit an innate immune response. The conservation of the selected proteins suggests the possibility of cross-protection in line with the One Health approach to disease control. The vaccine candidate was predicted to be both antigenic and immunogenic, and immune simulation analyses demonstrated its ability to elicit both humoral and cellular immune responses. Protein–protein docking and normal-mode analyses of the vaccine candidate with TLR4 predicted efficient binding and stable interaction. This study provides a promising One Health approach for the design of multi-epitope vaccines against human and livestock tuberculosis. Overall, the designed vaccine candidate demonstrated immunogenicity and safety features that warrant further experimental validation in vitro and in vivo. Full article
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<p>Graphic representation of the designed multi-epitope chimeric vaccine candidate, TB-MEVA−1. The 683-amino-acid polypeptide sequence containing a built-in adjuvant (orange) at the N-terminal linked to the multi-epitope sequence through an EAAAK linker (light blue) to the PADRE and TAT peptides, which are joined through GGGS linkers. Antigenic high-affinity HTL epitopes, as well as high-scoring LBL and CTL epitopes, are joined by AAY (yellow), GPGPG (light orange), and KK linkers (blue), respectively). A 10×His tag is added at the C-terminal to facilitate purification and identification, separated from the peptide epitopes using the HRV 3C protease cleavage sequence.</p>
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<p>Graphic representation of key secondary structure types of the designed subunit vaccine sequence. (<b>A</b>) The protein is predicted to comprise alpha helices (27.0%), beta strands (13.0%), and coils (58.0%), and (<b>B</b>) 31% of the amino acid residues are predicted by the DISOPRED3 server to be located in intrinsically unstructured regions. The dashed orange line indicates the disorder threshold (<b>C</b>). The 3D structure of the designed vaccine candidate shows the different secondary structure features, including helices (cyan), coils (red), and strands (magenta).</p>
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<p>Immunological simulation of the cytokine profile following three TB-MEVA−1 injections spaced 28 days apart. Following the three doses, the primary plot displays varying cytokine levels. The blue line in the insert figure represents the Simpson index, D, and the IL-2 level. D is a diversity metric. An increase in D over time denotes the emergence of distinct epitope-specific dominant T-cell clones. The diversity decreases with the D value.</p>
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<p>Protein modeling, refinement, and validation. (<b>A</b>) The initial 3D model of the multi-epitope vaccine candidate predicted on the ColabFold server. (<b>B</b>) Superimposition of the refined 3D structure (colored) on the initial “crude model” (gray) by the GalaxyRefine server. Validation of the refined model showing (<b>C</b>) Ramachandran plot analysis with 97.1% of residues in favored regions (A, B, L), 2.1% in allowed regions (a, b, l, p and ~a, ~b, ~l, ~p), and 0.2% of protein residues in disallowed (outlier) regions, and (<b>D</b>) the ProSA-web plot, with a Z-score of −4.92.</p>
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<p>Protein–protein interaction pocket prediction and molecular docking of vaccine candidate with the TLR4 receptor. (<b>A</b>) The largest predicted PPI pocket located at the interface of the designed chimeric vaccine candidate (red), with a surface area of 29,113.275 Å<sup>2</sup> and a surface volume of 129,803.080 Å<sup>3</sup>. (<b>B</b>) The docked complex of the designed vaccine candidate (red) with the Toll-like receptor 4 chain (green). (<b>C</b>) Interaction network of the vaccine candidate and TLR4, respectively; hydrogen bonding interactions are shown in blue. Non-bonded interactions and salt bridges are shown in orange. The positive, negative, neutral, aliphatic, and aromatic charged residues are shown in blue, red, green, gray, and purple colors, respectively.</p>
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<p>Molecular dynamics simulation analysis of the docked vaccine candidate–TLR4 complex. (<b>A</b>) The main-chain deformability of the TB-MEVA−1-TLR4 complex. (<b>B</b>) The B-factor quantifies the uncertainty of each atom. (<b>C</b>) The eigenvalue stipulates the movement stiffness linked to the normal modes. (<b>D</b>) The variance map is related to the individual variances (red) and the cumulative variances (green). (<b>E</b>) The covariance graph between pairs of residues shows the correlated (red), uncorrelated (white), or anti-correlated (blue) mobility of the pairs. (<b>F</b>) The elastic network model portrays the atom pairs linked by springs, with the darker grays indicating the spring stiffness.</p>
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<p>In silico model of elicited immune response by TB-MEVA−1, showing the (<b>A</b>) antigen and induced immunoglobulins, (<b>B</b>) B-cell population/state, (<b>C</b>) B-cell population, (<b>D</b>) TH cell population, (<b>E</b>) TH cell population/state, (<b>F</b>) TC cell population/state, (<b>G</b>) MA population per state, (<b>H</b>) dendritic cell population/state, and (<b>I</b>) natural killer cell population.</p>
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<p>Computational cloning of the gene coding for the designed vaccine candidate into the pET30a (+) expression vector. The red section denotes the gene coding for the vaccine candidate, while the black circle denotes the pET28(a)+ backbone. The 10xHis tag is placed at the carboxy-terminus of the vaccine candidate. The * in the BclI restriction enzyme indicates that the enzyme displays star activity.</p>
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<p>Workflow for the study. The approach began with identifying the target lipoproteins and carrying out a conservation analysis. CTL, HTL, and LBL epitope prediction; vaccine design, 3D structure modeling, refinement, and verification followed. Molecular docking of the validated 3D model with TLR4, molecular dynamics simulation, and in silico immune simulation studies was performed to investigate the potential of the vaccine candidate to elicit immune responses. Finally, reverse translation, codon optimization, and in silico cloning were performed.</p>
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16 pages, 7083 KiB  
Case Report
Comprehensive Management of a Giant Left Frontal AVM Coexisting with a Bilobed PComA Aneurysm: A Case Report Highlighting Multidisciplinary Strategies and Advanced Neurosurgical Techniques
by Corneliu Toader, Matei Serban, Razvan-Adrian Covache-Busuioc, Mugurel Petrinel Radoi, Alexandru Vlad Ciurea and Nicolaie Dobrin
J. Clin. Med. 2025, 14(4), 1232; https://doi.org/10.3390/jcm14041232 - 13 Feb 2025
Viewed by 296
Abstract
Background: Arteriovenous malformations (AVMs) are high-risk cerebrovascular anomalies that can lead to devastating complications, especially when associated with intracranial aneurysms. Their coexistence poses unique challenges in diagnosis and management due to heightened hemodynamic stress and rupture risks. This case presents a 35-year-old woman [...] Read more.
Background: Arteriovenous malformations (AVMs) are high-risk cerebrovascular anomalies that can lead to devastating complications, especially when associated with intracranial aneurysms. Their coexistence poses unique challenges in diagnosis and management due to heightened hemodynamic stress and rupture risks. This case presents a 35-year-old woman with a giant unruptured left frontal AVM and a bilobed posterior communicating artery (PComA) aneurysm, highlighting the critical role of advanced imaging, meticulous surgical planning, and individualized care in addressing complex cerebrovascular conditions. Methods: The patient presented with a generalized tonic–clonic seizure, her first-ever neurological event. Advanced imaging, including digital subtraction angiography and 3D rotational imaging, revealed a 3–4 cm AVM supplied by the left middle and anterior cerebral arteries, with venous drainage into the superior sagittal sinus. Additionally, an unruptured bilobed PComA aneurysm was identified. Given the AVM’s large size, high-flow dynamics, and significant rupture risk, surgical resection was prioritized. The aneurysm, being stable and anatomically distinct, was managed conservatively. Microsurgical techniques were employed to ensure complete AVM resection while preserving critical vascular and neurological structures. Results: Postoperative angiography confirmed the complete removal of the AVM without residual nidus or abnormal vascular connections. The patient recovered without complications, achieving seizure freedom and preserved neurological function. At the three-month follow-up, imaging showed a stable resection cavity and a hemodynamically stable aneurysm. Conclusions: This case demonstrates the power of multidisciplinary care and advanced neurosurgical techniques in achieving curative outcomes for complex cerebrovascular anomalies. It underscores the importance of risk-prioritized strategies and highlights emerging directions for the field, including AI-integrated imaging, hybrid treatment approaches, and long-term studies on hemodynamic stability post-resection. This case contributes valuable insights into optimizing outcomes for patients with coexisting AVMs and aneurysms, offering hope for those facing similarly challenging diagnoses. Full article
(This article belongs to the Special Issue Clinical Diagnosis and Treatment of Cerebrovascular Diseases)
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<p>Preoperative bilateral carotid angiography. (<b>A</b>) Frontal view showing arterial feeders from the left middle and anterior cerebral arteries. (<b>B</b>) Lateral view highlighting venous drainage into the superior sagittal and transverse sinuses.</p>
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<p>Three-dimensional rotational angiography. (<b>A</b>–<b>C</b>) Volumetric view of the AVM and its dimensions. (<b>D</b>,<b>E</b>) Close-up of the bilobed PComA aneurysm. (<b>F</b>,<b>G</b>) Dynamic flow characteristics of the AVM, emphasizing its high-pressure nature.</p>
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<p>Preoperative MRI. (<b>A</b>–<b>C</b>) T2-weighted axial, sagittal, and coronal images showing the AVM nidus and its flow void pattern. (<b>D</b>,<b>E</b>) Post-contrast sequences illustrating enhancement of the nidus and feeding arteries.</p>
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<p>Intraoperative observations of AVM resection. (<b>A</b>): The initial exposure of the left frontal AVM following a carefully crafted parasagittal frontoparietal craniotomy. The dura mater has been reflected, revealing the prominent cortical draining vein and the AVM’s vascular network. This image demonstrates the precision of the surgical exposure, highlighting the surrounding cortical tissue, which was preserved during the procedure. (<b>B</b>): The stepwise dissection of the AVM’s arterial feeders using microdissection techniques and high-magnification visualization. The feeding arteries are systematically coagulated and divided to progressively devascularize the nidus. The surrounding cortical vessels remain intact, underscoring the meticulous preservation of the normal brain vasculature. (<b>C</b>): The resection cavity after complete en bloc excision of the AVM. The cortical draining vein has visibly collapsed, indicating the cessation of abnormal arteriovenous shunting. The surgical field is hemostatic, with no evidence of residual nidus or bleeding, reflecting the precision of the procedure and thorough intraoperative inspection.</p>
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<p>Postoperative DSA confirmed complete resection of the AVM with no evidence of residual nidus or abnormal vascular structures. (<b>A</b>): This demonstrates the absence of the AVM nidus and feeding arteries, with no abnormal arteriovenous connections observed. (<b>B</b>): This highlights the normalization of the vascular flow in the left frontal region, with the superior sagittal sinus and surrounding cortical vessels remaining intact. (<b>C</b>): This provides a detailed view of the resection site, confirming the resolution of the high-flow dynamics previously associated with the AVM.</p>
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<p>Postoperative cranial CT provided additional confirmation of a favorable outcome, showing a well-defined resection cavity without complications. (<b>A</b>): This displays the resection cavity in the left frontal lobe, with no evidence of residual nidus, hemorrhage, or edema. (<b>B</b>): This confirms the preservation of midline structures, with no mass effect, hydrocephalus, or ischemic changes. The cerebroventricular system remains symmetrical and normal.</p>
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<p>Three-month follow-up CT. (<b>A</b>): This view demonstrates a hypodense area in the left frontal lobe, corresponding to the resection cavity from the excision of the AVM. The cavity appears well-defined with no evidence of residual nidus, hemorrhage, or ischemia. The surrounding parenchyma is preserved, with no signs of edema or other pathological changes. (<b>B</b>): The sagittal section highlights the absence of mass effect or midline shift. The resection cavity is visible, with well-preserved anatomical relationships in the adjacent regions. The cerebral parenchyma and midline structures remain intact, reflecting a stable postoperative condition. (<b>C</b>): The coronal view confirms the integrity of the cerebroventricular system, with no evidence of hydrocephalus or other abnormalities. The surgical site is clean, and there are no signs of postoperative complications, such as venous congestion or infarction.</p>
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20 pages, 7156 KiB  
Article
Spatial Distribution of Timbered Soil Physicochemical Properties and Their Effects on the Vegetation Indices in Tongzhou, Beijing
by Yufei Zhang, Senyang Li, Xiuzhong Li, Haibo Sun, Shuailing Hou, Xiujin Qi, Jin Cheng, Nan Zhang and Heran Dai
Forests 2025, 16(2), 327; https://doi.org/10.3390/f16020327 - 13 Feb 2025
Viewed by 357
Abstract
Tongzhou District is designated as a city sub-center with 33.3% forest cover, representing significant ecological value for Beijing. However, this extensive forest area has lacked detailed conservation measures, leading to inefficient resource utilization over the years. Therefore, determining the various maintenance measures for [...] Read more.
Tongzhou District is designated as a city sub-center with 33.3% forest cover, representing significant ecological value for Beijing. However, this extensive forest area has lacked detailed conservation measures, leading to inefficient resource utilization over the years. Therefore, determining the various maintenance measures for the different areas is very important. This study focused on exploring the relationship between the soil nutrient structure and vegetation indices in the area to develop a more precise plan for forest maintenance. This study collected 163 sample points in the four zones of Tongzhou district, including electrical conductivity, acidity and alkalinity, bulk density, soil organic matter, total nitrogen, available nitrogen, total phosphorus, total potassium, available potassium, available phosphorus, as well as vegetation characteristics such as richness, coverage, and height. The normalized difference vegetation index, difference vegetation index, ratio vegetation index, green light vegetation index, and soil-adjusted vegetation index were calculated by remote sensing images. To test the spatial distribution of soil nutrient construction and the relationship between soil and vegetation indices using the spatial interpolation method and Pearson correlation analysis, the results showed that: (1) The soil organic matter and total nitrogen were extremely low (1.282 and 0.461 g/kg). In contrast, the available and total potassium was extremely high (227.994 mg/kg and 16.866 g/kg); (2) High-value areas of available and total potassium are in the northern area, the available and total phosphorus in the central area, and the pH in the northeast area, with overall neutral-to-alkaline conditions; (3) The mean of coverage is 72.120, with high-value areas concentrated in northern parts of the central areas. While the overall coverage is extensive, height varies significantly (3.300–479.867), and high-density vegetation is limited to the northern part of the central area; (4) Vegetation height shows a significant negative correlation with total potassium and a significant positive correlation with pH values. We suggest that it is necessary to properly retain fallen leaves and dead grass in the forest to increase the organic matter content of the soil, apply more organic fertilizers, and supplement nitrogen fertilizers. In Tongzhou District, potassium fertilizer application should be reduced, particularly in the northeast and northern areas, to prevent excess fertility. In the central area, phosphorus fertilizer application should also be controlled, while in alkaline areas, fertilizer use should be optimized, and lime should be added to improve pH. Compost or humic acid can improve the soil’s ability to absorb and release phosphorus, thereby enhancing plant phosphorus uptake and increasing vegetation height and coverage. This study only analyzed spatial changes without further examining soil layer differences at varying depths and the effects of soil microorganisms. In the future, soil fertility in various depths and the functionality and diversity of soil microorganisms are worth further exploring. Full article
(This article belongs to the Section Forest Soil)
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<p>Regional overview map of Tongzhou District, showing the northern area (orange), northeast area (green), central area (blue), and southern area (pink), with sampling points marked as red dots.</p>
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<p>Spatial distribution results of soil chemical indicators in the afforestation area of the Tongzhou District plain. (<b>a</b>) Available potassium (AK), (<b>b</b>) Soil organic matter (SOM), (<b>c</b>) Total potassium (TK), (<b>d</b>) Total phosphorus (TP), (<b>e</b>) Available nitrogen (AN), (<b>f</b>) Available phosphorus (AP), (<b>g</b>) Total nitrogen (TN), (<b>h</b>) pH.</p>
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<p>Spatial distribution of soil physical indicators in Tongzhou District. (<b>a</b>) Electrical conductivity (EC), (<b>b</b>) Bulk density (BD).</p>
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<p>Spatial distribution of vegetation indicators in the plain afforestation area of Tongzhou District. (<b>a</b>) Richness (R), (<b>b</b>) Height (H), (<b>c</b>) Coverage (CVG), (<b>d</b>) Normalized Difference Vegetation Index (NDVI), (<b>e</b>) Soil Adjusted Vegetation Index (SAVI), (<b>f</b>) Ratio Vegetation Index (RVI), (<b>g</b>) Green Vegetation Index (GVI), (<b>h</b>) Difference Vegetation Index (DVI).</p>
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<p>Pearson product–moment correlation analysis between soil physical and chemical properties and vegetation indicators: (<b>a</b>) southern area, (<b>b</b>) northeast area, (<b>c</b>) central area, (<b>d</b>) northern area.</p>
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19 pages, 4923 KiB  
Article
Exploring Habitat Quality Dynamics in an Equatorial Andean Basin Under Scenarios of Land Use Change
by Lorena González, Darío Xavier Zhiña, Alex Avilés, Ana Astudillo, Ximena Peralta and Teodoro Verdugo
Earth 2025, 6(1), 10; https://doi.org/10.3390/earth6010010 - 12 Feb 2025
Viewed by 299
Abstract
Globally, ecosystem services face significant degradation due to land use and land cover change (LULC) driven by human development. Despite numerous habitat quality assessments, comprehensive studies in high-mountain equatorial region basins remain scarce. This research addresses assessing habitat quality in Ecuador’s sub-basins of [...] Read more.
Globally, ecosystem services face significant degradation due to land use and land cover change (LULC) driven by human development. Despite numerous habitat quality assessments, comprehensive studies in high-mountain equatorial region basins remain scarce. This research addresses assessing habitat quality in Ecuador’s sub-basins of the Aguilán and Tabacay Rivers, with projections extending to 2050. This study considered anthropogenic threats and examined two land use change scenarios. The “Integrated Valuation of Ecosystem Services and Tradeoffs” (InVEST) model was used for the evaluation. A habitat quality index (HQI) was developed and categorized into five classes. The results showed that in 2018, over 50% of the study area had medium, high, and very high habitat quality levels, partly due to implementing policies, such as Reciprocal Water Agreements, developed by local initiatives. However, future projections suggest a declining trend, particularly in urban and cropland areas, highlighting the need to reinforce proactive policies. The findings of this study contribute to addressing existing gaps in habitat quality research in high-mountain regions, providing key scientific evidence to support conservation strategies, land use planning, and watershed management. Full article
38 pages, 13127 KiB  
Article
In the Footsteps of Tradition: Reinventing the Paths of Santa Faz Within the Paradigm of Sustainability and Territorial Development in Alicante
by Pablo Rosser and Seila Soler
Religions 2025, 16(2), 224; https://doi.org/10.3390/rel16020224 - 12 Feb 2025
Viewed by 327
Abstract
The Santa Faz Pilgrimage, with over 600 years of history and as Spain’s second most significant pilgrimage, is at a critical point due to urbanization and inadequate planning. This study explores revitalizing and enhancing the historical Santa Faz routes, integrating cultural tourism, environmental [...] Read more.
The Santa Faz Pilgrimage, with over 600 years of history and as Spain’s second most significant pilgrimage, is at a critical point due to urbanization and inadequate planning. This study explores revitalizing and enhancing the historical Santa Faz routes, integrating cultural tourism, environmental sustainability, and socioeconomic benefits. Recognized as an Intangible Cultural Heritage, the pilgrimage impacts Alicante’s cultural landscape yet faces pressure from modern urban development. Using a multidisciplinary approach aligned with the UN’s 2030 Sustainable Development Goals, the study proposes alternative routes, such as a “green route” through ancient paths and water routes, a Villafranqueza route, and one from the former Monastery of Los Ángeles. These paths would be revived through local reforestation, sustainable tourism infrastructure, and rest areas for pilgrims. The restoration of the Santa Faz paths is seen as vital for cultural heritage conservation, sustainable tourism, and job creation, with both opportunities and challenges in integrating these routes into the Council of Europe’s Cultural Routes. The study advocates modifying the urban plan and promoting employment in heritage and tourism management, emphasizing the need for ongoing research and cross-disciplinary collaboration to secure the long-term preservation and development of these culturally significant spaces. Full article
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<p>Physical framework through which the Santa Faz Pilgrimage (Alicante) takes place, with the monastery located near Monte del Pino de Alberola.</p>
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<p>Ancient weir of Mutxamel, possibly of Muslim origin but significantly transformed in the 16th century. Source: Private collection.</p>
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<p>Santa Faz road network in the Huerta de Alicante. Road Network: 1. Villafranqueza Path. 2. Tángel Path. 3. Old Valencia Path. 4. Villafranqueza to the Sea Path. 5. Santa Faz Path. 6. Mutxamel Path. 7. Stone Cross Path. 8. Benimagrell Path. 9. Huerta Path. 10. San Juan Beach Path. 11. Albufereta Path. 12. Los Ángeles to Creu de Fusta Path. Sources: VARELA (1984). Official Cartography scale 1:10,000.</p>
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<p>Irrigation map of the Alicante Reservoir (19th century). Source: Private collection.</p>
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<p>Photograph of the Torre del Ciprés and adjacent Hermitage, built during the 16th–17th centuries. Source: Private collection.</p>
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<p>17th-century graffiti preserved in the Casa Capiscol in the Huerta of Alicante, depicting members of a Company of Knights recovering loot captured by a group of Berbers.</p>
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<p>Map showing the location of towers in the Huerta of Alicante. Source: Private collection.</p>
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<p>Photograph of paths, dry stone walls, vegetation, etc., in the Huerta of Alicante. Source: Plinthus Collection.</p>
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<p>The Holy Face, held by two angels and painted by Juan Sánchez Cotán (1620–1625), from the Monastery of La Cartuja in Granada.</p>
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<p>Wooden panel from the old altarpiece of the Church of Santa Faz in the Monastery of the same name (15th century) depicting this first miracle. Source: Photograph by the authors.</p>
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<p>Detail of one of the canvases by the painter Conchillos in the Camarín de la Santa Faz (17th century), depicting the second miracle. Source: Photograph by the authors.</p>
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<p>Photograph of the Pilgrimage passing through the current Avenida de Denia (19th century). Source: Seguí Collection. Department of Memory of Alicante, Alicante City Council.</p>
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<p>Photograph of the Pilgrimage passing through the current Avenida de Denia (19th century). Source: MyHeritage.</p>
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<p>Photograph of the Pilgrimage passing through Raval Roig (1840s). Source: Alicante Municipal Archive.</p>
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<p>Photograph of the Cruz de Fusta on the current Avenida de Denia (1840s). Source: Alicante Municipal Archive.</p>
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<p>Photograph of the Pilgrimage passing through the current Jovellanos Street (19th century). Source: Seguí Collection. Department of Memory of Alicante, Alicante City Council.</p>
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<p>Photograph of the Pilgrimage passing through the current Avenida de Denia, showing the Knight Custodians on horseback (19th century). Source: Seguí Collection. Department of Memory of Alicante, Alicante City Council.</p>
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<p>Photograph of the sale of water jugs, pitchers, and other ceramic items in the plaza of the Monastery of Santa Faz (1840s). Source: Alicante Municipal Archive.</p>
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<p>Recreation of the Santa Faz Pilgrimage based on photographs. Source: authors.</p>
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<p>Centuries-Old Paths of Santa Faz. Source: Belén Alejandro, Designer.</p>
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<p>Project: The Paths of the Holy Face.</p>
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<p>Audience attending our seminar on Santa Faz. Source: authors.</p>
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<p>Heatmap showing the strengths of the relationship between key ideas about Santa Faz and the two surveyed groups. Own elaboration.</p>
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31 pages, 14820 KiB  
Article
Digital Transformation in African Heritage Preservation: A Digital Twin Framework for a Sustainable Bab Al-Mansour in Meknes City, Morocco
by Imane Serbouti, Jérôme Chenal, Saâd Abdesslam Tazi, Ahmad Baik and Mustapha Hakdaoui
Smart Cities 2025, 8(1), 29; https://doi.org/10.3390/smartcities8010029 - 12 Feb 2025
Viewed by 605
Abstract
The advent of digital transformation has redefined the preservation of cultural heritage and historic sites through the integration of Digital Twin technology. Initially developed for industrial applications, Digital Twins are now increasingly employed in heritage conservation as dynamic, digital replicas of physical assets [...] Read more.
The advent of digital transformation has redefined the preservation of cultural heritage and historic sites through the integration of Digital Twin technology. Initially developed for industrial applications, Digital Twins are now increasingly employed in heritage conservation as dynamic, digital replicas of physical assets and environments. These systems enable detailed, interactive approaches to documentation, management, and preservation. This paper presents a detailed framework for implementing Digital Twin technology in the management of heritage buildings. By utilizing advanced methods for data collection, processing, and analysis, the framework creates a robust data hub for Digital Twin Heritage Buildings (DTHB). This architecture enhances real-time monitoring, improves accuracy, reduces operational costs, and enables predictive maintenance while minimizing invasive inspections. Focusing on Bab Al-Mansour Gate in Meknes, Morocco, a significant cultural landmark, this research outlines the workflow for developing a Bab Al-Mansour DTHB platform. The platform monitors structural health and detects damage over time, offering a dynamic tool for conservation planning. By integrating innovative technologies with data-driven solutions, this study provides a replicable model for preserving heritage sites, addressing critical gaps in real-time monitoring, resource optimization, and environmental risk mitigation. Full article
(This article belongs to the Collection Digital Twins for Smart Cities)
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<p>Bab Al-Mansour: (<b>a</b>) regional location and (<b>b</b>) monument detail.</p>
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<p>Architectural details of Bab Al-Mansour gate: (<b>a</b>) main arch, (<b>b</b>) lower arches, (<b>c</b>) decorative tilework, (<b>d</b>) column Capital, and (<b>e</b>) mosaic patterns.</p>
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<p>Visualization of Bab Al-Mansour in blue square from LoD 0 to LoD 1 with 2.5D DEM integration: (<b>a</b>) LoD 0 with context, (<b>b</b>) LoD 0 with RBV imagery, (<b>c</b>) LoD 1 with 2.5D SRTM DEM, (<b>d</b>) Enhanced LoD 1 with zoomed-in 2.5D visualization.</p>
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<p>(<b>a</b>) Cloud point data cleaned, registered, resampled, color mapped, and texture draped by the image in (<b>b</b>) acquired by optical sensor.</p>
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<p>Data Hub Architecture for DT<sub>HB</sub>: sources, storage, and analytics.</p>
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<p>Key elements of a DT<sub>HB</sub> framework: physical entities (PE), virtual entities (VE), connected data (I) and governing integration and processes (IP).</p>
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<p>From the HBIM-based to DT<sub>HB</sub> workflow.</p>
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<p>Process flow for HBIM from data collection to semantic annotation.</p>
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<p>Workflow for HBIM model construction.</p>
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<p>(<b>a</b>) Web integration of HBIM using CityGML and (<b>b</b>) detailed geometry and property analysis via Feature Manipulation Engine inspector.</p>
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<p>Probabilistic graphical model for coupled evolution of physical and digital spaces in a heritage building Digital Twin framework.</p>
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<p>General framework illustrating the integration of HBIM, DT<sub>HB</sub>, and data hub DT<sub>HB</sub>.</p>
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<p>(<b>a</b>) Structural representation of Al-Mansour Gate for Digital Twin modeling and (<b>b</b>) textural information modeling from cloud point of Bab Al-Mansour.</p>
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<p>(<b>a</b>) IFC-based 3D mesh classification of Bab Al-Mansour pillar and (<b>b</b>) verticality analysis with decay property set.</p>
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<p>(<b>a</b>) Point cloud-based 3D model of Bab Al-Mansour and (<b>b</b>) textured optical sensor model of Bab Al-Mansour.</p>
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<p>Framework for AI-Enhanced Digital Twin simulations and user interaction in heritage preservation.</p>
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11 pages, 3578 KiB  
Review
Review on the Management of Female Urinary Incontinence and Anterior Vaginal Prolapse
by Ronscardy F. Mondesir, Angelica Gousse, Daniel A. Boaretto, Daniel Ajabshir and Angelo Gousse
Soc. Int. Urol. J. 2025, 6(1), 12; https://doi.org/10.3390/siuj6010012 - 12 Feb 2025
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Abstract
Objectives: We aimed to evaluate management strategies for female urinary incontinence, specifically stress urinary incontinence (SUI), and anterior vaginal prolapse (pelvic organ prolapse, POP), emphasizing diagnostic methods, treatment options, and factors influencing surgical outcomes. Methods: We conducted a thorough literature review examining diagnostic [...] Read more.
Objectives: We aimed to evaluate management strategies for female urinary incontinence, specifically stress urinary incontinence (SUI), and anterior vaginal prolapse (pelvic organ prolapse, POP), emphasizing diagnostic methods, treatment options, and factors influencing surgical outcomes. Methods: We conducted a thorough literature review examining diagnostic tools, including physical examinations, urodynamic testing, and pessary evaluations, alongside treatment options for SUI and POP. Both surgical interventions, such as mid-urethral sling placement and anterior colporrhaphy, and non-surgical methods, including pelvic floor exercises, were analyzed. This review assesses these approaches’ efficacy, complications, and outcomes, incorporating current clinical guidelines and evidence-based practices. Results: Evidence indicates that SUI frequently coexists with POP, with a notable proportion of cases being occult until a prolapse is reduced. Diagnostic methods such as pessary testing and urodynamic evaluations are essential in identifying masked SUI, though their predictive accuracy varies. Surgical techniques such as using mid-urethral slings are highly effective but pose risks, including voiding dysfunction and lower urinary tract injury. Long-term data emphasize the need for personalized treatment strategies, with combined procedures showing superior outcomes for the concurrent management of POP and SUI in select cases. Conclusions: Effective management of SUI and POP requires a personalized approach, factoring in the severity of a prolapse and the likelihood of postoperative incontinence. While conservative treatments are practical initial options, surgical solutions, such as mid-urethral slings and apical suspension procedures, offer robust, lasting results for advanced cases. Preoperative diagnostics, collaborative decision-making, and tailored treatment plans are essential to optimize success and minimize complications. Future research should prioritize enhancing diagnostic precision and refining surgical methods to further advance patient care. Full article
Show Figures

Figure 1

Figure 1
<p>Pelvic examination of high-grade pelvic organ prolapse (stage IV).</p>
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<p>MRI—T2 weighted image of high-grade anterior compartment prolapse.</p>
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<p>Dissection of high-grade cystocele after retropubic sling placement.</p>
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<p>Dissection of high-grade cystocele after retropubic sling placement.</p>
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<p>POP Q staging of pelvic organ prolapse.</p>
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<p>The surgical placement of a Lynx Suprapubic Mid-Urethral Sling to treat stress incontinence. (<b>a</b>) A complete anterior compartment prolapse with the sling delivery device placed suprapubically. (<b>b</b>,<b>c</b>) Placement and tightening of the mid-urethral sling.</p>
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<p>Decision-making flowchart for women undergoing prolapse surgery with or without SUI.</p>
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