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Search Results (438)

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18 pages, 5559 KiB  
Article
The Construction of a Digital Agricultural GIS Application Suite
by Di Hu, Zongxiang Zhang, Xuejiao Ma, Duo Bian, Yihao Man, Jun Chang and Runxuan Qian
Appl. Sci. 2024, 14(22), 10710; https://doi.org/10.3390/app142210710 - 19 Nov 2024
Viewed by 277
Abstract
With the increasing expansion and deepening of GIS applications across diverse industries, the limitations of industry-specific GIS application systems in terms of development efficiency, flexibility, and customization have become increasingly apparent. This paper employes the concept of application suites and proposes a design [...] Read more.
With the increasing expansion and deepening of GIS applications across diverse industries, the limitations of industry-specific GIS application systems in terms of development efficiency, flexibility, and customization have become increasingly apparent. This paper employes the concept of application suites and proposes a design approach for tailored GIS application suites in digital agriculture, considering its specific application requirements. Additionally, it outlines an implementation method based on low-code development and microservice technologies. A GIS application system for digital agriculture was developed to conduct experimental validation. The results indicate that the GIS application suite developed in this study demonstrates readily deployable characteristics, granular assembly capabilities, and ease of scalability, facilitating the rapid development of customized GIS applications for digital agriculture. This approach enhances both development efficiency and flexibility while meeting the customization needs inherent to such applications. Full article
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<p>Digital agricultural GIS application suite design concept.</p>
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<p>Application component architecture.</p>
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<p>The microservice architecture designed for the digital agricultural GIS application.</p>
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<p>Continuous integration of microservices.</p>
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<p>Application component implementation effect preview (agricultural thematic map component).</p>
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<p>Application component implementation effect preview (evaluation of planting suitability component).</p>
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<p>The modules of the digital agricultural GIS application system.</p>
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<p>The routing relationships between pages and routes in the application system.</p>
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<p>Digital agricultural GIS application system based on application suite.</p>
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11 pages, 870 KiB  
Review
Sjögren’s Disease and Gastroesophageal Reflux Disease: What Is Their Evidence-Based Link?
by Diana Mieliauskaitė and Vilius Kontenis
Medicina 2024, 60(11), 1894; https://doi.org/10.3390/medicina60111894 - 18 Nov 2024
Viewed by 424
Abstract
Sjögren’s disease (SjD), or primary Sjögren’s syndrome (pSS), is a heterogeneous chronic autoimmune disorder with multiple clinical manifestations that can develop into non-Hodgkin’s lymphoma in mucosa-associated lymphoid tissue. SjD is one of the autoimmune diseases with the maximum delayed diagnosis due to its [...] Read more.
Sjögren’s disease (SjD), or primary Sjögren’s syndrome (pSS), is a heterogeneous chronic autoimmune disorder with multiple clinical manifestations that can develop into non-Hodgkin’s lymphoma in mucosa-associated lymphoid tissue. SjD is one of the autoimmune diseases with the maximum delayed diagnosis due to its insidious onset, heterogeneous clinical features and varied course. It is increasingly recognized that extraglandular manifestations represent a clinical challenge for patients with SjD. The European League Against Rheumatism (EULAR) Sjögren’s Syndrome (SS) Disease Activity Index (ESSDAI) is a systemic disease activity index designed to measure disease activity in patients with primary Sjogren’s syndrome. It consists of 12 domains: cutaneous, pulmonary, renal, articular, muscular, peripheral nervous system, central nervous system, hematological, glandular, constitutional, lymphadenopathy and lymphoma, biological. More than a quarter of patients with pSS may have systemic features that are not included in the ESSDAI classification, i.e., various cardiovascular, ophthalmic, ENT, and other systemic or organ involvement that increase the magnitude of the systemic phenotype in the disease. The ESSDAI also excludes the gastrointestinal (GI) tract, and unfortunately, GI manifestations are not routinely assessed. Gastroesophageal reflux disease (GERD) is one of the most prevalent gastrointestinal disorders, impairing quality of life and consuming a large volume of medical resources. Recently carried out the Mendelian randomized trial confirmed the causal link between SjD and gastroesophageal reflux disease (GERD) and showed that GERD is a risk factor for SjD. This review aims to provide an overview of the research describing evidenced based links between Sjögren’s disease and gastroesophageal reflux disease, with the intention of ensuring that any systemic pathology in Sjögren’s disease is properly assessed and that management of the disease is directed towards the patient. A comprehensive literature search was carried out on PubMed, Web of Science, Scopus and the Cochrane Library databases. Two researchers searched for published studies indexed from inception to 1 September 2024 using the keywords ‘Sjögren’s syndrome’ OR ‘Sjögren’s disease’ AND ‘gastroesophageal reflux disease’ AND ‘microbiota’ OR microbiota dysbiosis’. We limited our search for scientific articles to human studies, and only included articles in English. Overall, there is a lack of evidence-based studies assessing the association between GERD and Sjögren’s disease and the changes in the microbiota associated with GERD in a multidisciplinary setting. Such studies are needed for the future, as this will improve the early diagnosis of Sjögren’s disease and the personalized management of the disease. Full article
(This article belongs to the Special Issue Recent Advances in Autoimmune Rheumatic Diseases: 2nd Edition)
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<p>The European League Against Rheumatism (EULAR) Sjögren’s Syndrome (SS) Disease Activity Index (ESSDAI)—a systemic disease activity index designed to measure disease activity in patients with primary Sjogren’s syndrome.</p>
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<p>The association between Sjogren’s disease and gastroesophageal reflux disease.</p>
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28 pages, 12052 KiB  
Article
Web-GIS Application for Hydrogeological Risk Prevention: The Case Study of Cervo Valley
by Davide Lorenzo Dino Aschieri, Noemi Sobrino and Enrico Macii
Sustainability 2024, 16(22), 9833; https://doi.org/10.3390/su16229833 - 11 Nov 2024
Viewed by 534
Abstract
Natural disasters have increasingly threatened human life, infrastructure, and ecosystems, exacerbated by climate change, urbanization, and deforestation. Effective disaster risk management is crucial to mitigate these impacts. Traditionally, Geographic Information Systems (GISs) have provided spatial data analysis capabilities, but the advent of Web-GIS [...] Read more.
Natural disasters have increasingly threatened human life, infrastructure, and ecosystems, exacerbated by climate change, urbanization, and deforestation. Effective disaster risk management is crucial to mitigate these impacts. Traditionally, Geographic Information Systems (GISs) have provided spatial data analysis capabilities, but the advent of Web-GIS applications has revolutionized this field. Web-GIS platforms enable real-time data access and facilitate enhanced stakeholder collaboration. This paper details the development of a Web-GIS application tailored for hydrogeological risk management in Cervo Valley, part of the NODES—Nord Ovest Digitale e Sostenibile project under Italy’s National Recovery and Resilience Plan (NRRP). The application integrates both static and dynamic geospatial data to create an interactive interface for evaluating and planning responses to hydrogeological hazards, specifically floods, landslides, and debris flow cones. By utilizing advanced Web-GIS capabilities, the project aims to refine the risk management practices and decision-making processes, thereby bolstering territorial resilience and addressing contemporary spatial challenges with enhanced precision and efficiency. Full article
(This article belongs to the Special Issue GIS Implementation in Sustainable Urban Planning)
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<p>Location of Cervo Valley in the 5 m Digital Terrain Model (DTM). (<b>a</b>) Zoomed view of Cervo Valley, highlighting the locations of Piedicavallo and Biella. (<b>b</b>) Overview of the Cervo Valley in the Piedmont DTM. (<b>c</b>) Hydrographic network of the valley, showing the Cervo Stream and its main tributaries: Mologna, Irogna, and Rio Valdescola.</p>
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<p>Proposed architecture schema for generating web maps. The data were downloaded from open-source government sources, managed with QGIS3.36.3, and exported to the web using dedicated plugins.</p>
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<p>Key steps of the GRASS algorithm. (<b>a</b>) Digital Terrain Model (DTM) with filled sinks. The elevation gradient is represented by color, where green/yellow indicates higher elevations and purple indicates lower elevations. (<b>b</b>) Grayscale representation of the flow accumulation and flow direction (<b>c</b>) Basin delineation and hydrographic network with catchment area in red and river network in blue. (<b>d</b>) Shapefile creation. Each number in the figure corresponds to steps in <a href="#sec2dot3dot2-sustainability-16-09833" class="html-sec">Section 2.3.2</a>. Specifically: (1) Filled Digital Terrain Model, (2) Flow Accumulation and Direction, (3) River Channel Extraction, (4) Outlet Point Referencing, and (5) Conversion to Shapefile.</p>
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<p>Differences between raster files. (<b>a</b>) DTM with a resolution of 25 m (DTM 25m), showing broader terrain features with less detail. (<b>b</b>) DTM with a resolution of 5 m (DTM 5m), highlighting finer terrain details.</p>
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<p>Example of socio-economic layers in the town of Biella. In order, roads, buildings, the hydrographic network, and green areas are overlaid. (<b>a</b>) Roads layer in grayscale, representing the transportation network. (<b>b</b>) Roads and buildings layer in grayscale, adding structural elements of the town. (<b>c</b>) Combined layers showing roads, buildings, hydrographic network (in blue), and green areas (in green) for a comprehensive view of the socio-economic structure. Each color in part (<b>c</b>) represents a different layer: roads in white, buildings in grey, water bodies in blue, and green spaces in green.</p>
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<p>Natural risks and infrastructure at risk in the study area. Each color represents a specific risk layer. (<b>a</b>) Flood risk layer, showing areas subject to flooding in blue. (<b>b</b>) Landslide risk layer, showing areas subject to landslide in light green. (<b>c</b>) Debris flow cones layer, showing areas subject to Debris flow cones in pink. (<b>d</b>) Combined view of flood risk and buildings and infrastructure, in yellow, subjected to flood risk. (<b>e</b>) Combined view of landslide risk and buildings and infrastructure, in red, subjected to landslide risk. (<b>f</b>) Combined view of debris flow risk and buildings and infrastructure, in light blue, subjected to debris flow risk.</p>
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<p>Analysis of the rock face located behind the Saint Giovanni Andorno Sanctuary. (<b>a</b>) 3D and 2D visualization of the area of interest. (<b>b</b>) 2D slope analysis derived from the custom Python script using the DTM 5m dataset (varying colors refers to distinct slopes values). (<b>c</b>) Same layer as (<b>b</b>), but with a 3D view. (<b>d</b>,<b>e</b>) Photographs of the actual site from Google Maps [<a href="#B60-sustainability-16-09833" class="html-bibr">60</a>]. The results indicate no areas with slopes between 70 and 100%, likely due to the rock face’s limited height of approximately 5 m.</p>
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<p>Verification of elevation shapefiles using Python for 3D map generation. (<b>a</b>–<b>d</b>) Different views of the Zumaglia municipality are shown, with buildings and streets highlighted in red.</p>
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<p>A general representation of the pop-up representing the precipitation data registered in Piedicavallo pluviometer. (<b>a</b>) 2D view. (<b>b</b>) 3D view. Graphs in blue represent precipitation.</p>
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<p>This chart summarizes the computational effort to create 2D 25 m (in orange), 2D 5 m (in blue), 3D 25 m (in red), and 3D 5 m (in green). On the four axes, the chart contains, respectively, the number of faces (-), number of vertexes (-), rendering time (s), and file size (MB). All the measures have been normalized.</p>
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<p>2D/3D comparison of flood risk. (<b>a</b>,<b>c</b>) 2D and 3D views of flooded areas in the municipality of Biella, shown in blue. Green areas are represented in light green. (<b>b</b>,<b>d</b>) 2D and 3D views of buildings and streets at risk of flooding in the municipality of Biella, highlighted in yellow. White and grey areas represent streets and buildings in safe zones, while black areas indicate non-urbanized regions.</p>
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<p>2D/3D comparison of debris cone risk. (<b>a</b>,<b>c</b>) 2D and 3D view of the debris cone areas in Rosazza municipality, shown in pink. (<b>b</b>,<b>d</b>) 2D and 3D views of buildings and streets exposed to debris cone risk in the municipality of Rosazza, highlighted in light blue. The figures also show flood areas in blue and landslide areas in green and light green. The light blue sphere represents a queriable sensor point.</p>
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<p>2D/3D comparison of landslide risk. (<b>a</b>,<b>c</b>) 2D and 3D view of the landslide areas in Sagliano Micca municipality, in green. (<b>b</b>,<b>d</b>) 2D and 3D view of buildings and streets subjected to landslide risk in Sagliano Micca municipality, highlighted in red. The figures also show flood areas in blue. This risk refers to landslides identified by the PAI.</p>
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<p>(<b>a</b>) Slope terrain layer between 15 and 30%, shown in sea green. The river network in represented in blue. (<b>b</b>) 3D view of streets and buildings at risk of quick drips, highlighted in violet. The slope between 15 and 30% is represented in blue, streets in white and landslide in yellow.</p>
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<p>(<b>a</b>) Slope terrain layer between 35 and 70%, shown in yellow. The river network in represented in blue. (<b>b</b>) 3D view of streets and buildings at risk of complex terrain movements, highlightrd in red. Slope between 35 and 70% is represented in purple, streets in white and debris cones in pink.</p>
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22 pages, 1138 KiB  
Systematic Review
A Systematic Review of the Twelve Most Popular Bean Varieties, Highlighting Their Potential as Functional Foods Based on the Health Benefits Derived from Their Nutritional Profiles, Focused on Non-Communicable Diseases
by Maria Dimopoulou, Patroklos Vareltzis and Olga Gortzi
Appl. Sci. 2024, 14(22), 10215; https://doi.org/10.3390/app142210215 - 7 Nov 2024
Viewed by 546
Abstract
According to the US Department of Agriculture, more than 4000 types of beans are cultivated in the United States and worldwide; nevertheless, the demand for beans continues to rise. To some extent, diet can treat inflammation and consequently reduce the chances of developing [...] Read more.
According to the US Department of Agriculture, more than 4000 types of beans are cultivated in the United States and worldwide; nevertheless, the demand for beans continues to rise. To some extent, diet can treat inflammation and consequently reduce the chances of developing comorbidities, such as diabetes. A diet based on alternative plant protein sources, such as beans, is a sustainable solution for overall health due to the overconsumption of meat that characterizes Western societies and is even more important for regions that suffer from malnutrition, such as Africa. Reviewing the nutritional profile of the different varieties of beans produced in various locations would help enhance their quality, strengthen the role of producer groups, and protecting Geographical Indications (GI), thereby increasing simplification, sustainability, and transparency towards consumers. PubMed-Medline, Web of Science, Scopus, and Cochrane Library databases were searched for relevant articles published by 30 March 2024. The results have given the green light to the reform of EFSA rules, strengthening the health claims of beans, protecting the GI for each variety, and also highlighting the public demands for functional foods based on the nutritional aspects of this product and its impact on disease management or prevention. Full article
(This article belongs to the Special Issue Enrichment of Foods with Phytonutrients)
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<p>Prisma flow chart of the study (version 2020). * PubMed 147, Web of Science 180, Scopus 2, Cochrane Library 7. ** Excluded by the researchers due to sample parameters (small sample) or examined/analyzed varieties that were not included in this review (<a href="http://www.prisma-statement.org/" target="_blank">http://www.prisma-statement.org/</a>).</p>
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<p>Types of Beans (<a href="https://www.onlyfoods.net/different-types-of-beans.html" target="_blank">https://www.onlyfoods.net/different-types-of-beans.html</a>, accessed on 31 July 2020).</p>
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<p>The gut microbiota is modulated by dietary natural plants (Cao et al., 2019) [<a href="#B113-applsci-14-10215" class="html-bibr">113</a>].</p>
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21 pages, 15197 KiB  
Article
Correlation Analysis of Vertical Ground Movement and Climate Using Sentinel-1 InSAR
by Francesco Pirotti, Felix Enyimah Toffah and Alberto Guarnieri
Remote Sens. 2024, 16(22), 4123; https://doi.org/10.3390/rs16224123 - 5 Nov 2024
Viewed by 409
Abstract
Seasonal vertical ground movement (SVGM), which refers to the periodic vertical displacement of the Earth’s surface, has significant implications for infrastructure stability, agricultural productivity, and environmental sustainability. Understanding how SVGM correlates with climatic conditions—such as temperatures and drought—is essential in managing risks posed [...] Read more.
Seasonal vertical ground movement (SVGM), which refers to the periodic vertical displacement of the Earth’s surface, has significant implications for infrastructure stability, agricultural productivity, and environmental sustainability. Understanding how SVGM correlates with climatic conditions—such as temperatures and drought—is essential in managing risks posed by land subsidence or uplift, particularly in regions prone to extreme weather events and climate variability. The correlation of periodic SVGM with climatic data from Earth observation was investigated in this work. The European Ground Motion Service (EGMS) vertical ground movement measurements, provided from 2018 to 2022, were compared with temperature and precipitation data from MODIS and CHIRP datasets, respectively. Measurement points (MP) from the EGMS over Italy provided a value for ground vertical movement approximately every 6 days. The precipitation and temperature datasets were processed to provide drought code (DC) maps calculated ad hoc for this study at a 1 km spatial resolution and daily temporal resolution. Seasonal patterns were analyzed to assess correlations with Spearman’s rank correlation coefficient (ρ) between this measure and the DCs from the Copernicus Emergency Management Service (DCCEMS), from MODIS + CHIRP (DC1km) and from the temperature. The results over the considered area (Italy) showed that 0.46% of all MPs (32,826 MPs out of 7,193,676 MPs) had a ρ greater than 0.7; 12,142 of these had a positive correlation, and 20,684 had a negative correlation. DC1km was the climatic factor that provided the highest number of correlated MPs, roughly giving +59% more correlated MPs than DCCEMS and +300% than the temperature data. If a ρ greater than 0.8 was considered, the number of MPs dropped by a factor of 10: from 12,142 to 1275 for positive correlations and from 20,684 to 2594 for negative correlations between the DC1km values and SVGM measurements. Correlations that lagged in time resulted in most of the correlated MPs being within a window of ±6 days (a single satellite overpass time). Because the DC and temperature are strongly co-linear, further analysis to assess which was superior in explaining the seasonality of the MPs was carried out, resulting in DC1km significantly explaining more variance in the SVGM than the temperature for the inversely correlated points rather than the directly correlated points. The spatial distribution of the correlated MPs showed that they were unevenly distributed in clusters across the Italian territory. This work will lead to further investigation both at a local scale and at a pan-European scale. An interactive WebGIS application that is open to the public is available for data consultation. This article is a revised and expanded version of a paper entitled “Detection and correlation analysis of seasonal vertical ground movement measured from SAR and drought condition” which was accepted and presented at the ISPRS Mid-Term Symposium, Belem, Brasil, 8–12 November 2024. Data are shared in a public repository for the replication of the method. Full article
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<p>Combined drought indicators for the first 10-day period of July 2022 in Italy (JRC, 2024). This plot shows drought alert indicators over the northern regions, where a state of emergency was declared for this year. This event was an exceptional incident as, in general, the south of Italy is warmer than the north.</p>
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<p>Flowchart of the methodology.</p>
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<p>Histogram of frequency distribution of Spearman correlation values (<math display="inline"><semantics> <mi>ρ</mi> </semantics></math>) between <math display="inline"><semantics> <mrow> <mi>D</mi> <msub> <mi>C</mi> <mrow> <mn>1</mn> <mi>km</mi> </mrow> </msub> </mrow> </semantics></math> and SVGM at MPs [<a href="#B1-remotesensing-16-04123" class="html-bibr">1</a>].</p>
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<p>Lag time distribution of best correlations between <math display="inline"><semantics> <mrow> <mi>D</mi> <msub> <mi>C</mi> <mrow> <mn>1</mn> <mi>km</mi> </mrow> </msub> </mrow> </semantics></math> and SVGM [<a href="#B1-remotesensing-16-04123" class="html-bibr">1</a>].</p>
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<p>Lag time distribution of best correlations between temperature derived from calibrated MODIS and SVGM [<a href="#B1-remotesensing-16-04123" class="html-bibr">1</a>].</p>
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<p>(<b>a</b>) Pairwise <math display="inline"><semantics> <mrow> <mi>D</mi> <msub> <mi>C</mi> <mrow> <mi>C</mi> <mi>E</mi> <mi>M</mi> <mi>S</mi> </mrow> </msub> </mrow> </semantics></math>–<math display="inline"><semantics> <mrow> <mi>D</mi> <msub> <mi>C</mi> <mrow> <mn>1</mn> <mi>km</mi> </mrow> </msub> </mrow> </semantics></math> values of correlations with ground motion; (<b>b</b>) temperature vs. <math display="inline"><semantics> <mrow> <mi>D</mi> <msub> <mi>C</mi> <mrow> <mn>1</mn> <mi>km</mi> </mrow> </msub> </mrow> </semantics></math> correlation. Top and bottom rows are negative and positive (<math display="inline"><semantics> <mi>ρ</mi> </semantics></math>) values from correlation testing with SVGM [<a href="#B1-remotesensing-16-04123" class="html-bibr">1</a>].</p>
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<p>Top row shows the spatial distribution of negative and positive correlations (<b>left</b> and <b>right</b>) in terms of the percentage of correlated MPs with respect to the total number of MPs recorded by the European Ground Motion Service. The percentage was calculated over a regular hexagon grid overlaid onto the study area. Bottom row pinpoints areas (red dots) with the highest percentage of correlated MPs, negative (<b>bottom-left</b>) and positive (<b>bottom-right</b>).</p>
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<p>Measurement points with positive (<b>a</b>,<b>b</b>) and negative (<b>c</b>,<b>d</b>) Spearman correlation values.</p>
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<p>Time series plot showing the correlations at the respective measurement points in <a href="#remotesensing-16-04123-f008" class="html-fig">Figure 8</a>.</p>
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<p>“Viadotto Gorsexio” with a central pillar taller than 172 m.</p>
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<p>Display of information related to EGMS and climate correlation values of the area in the WebGIS viewer.</p>
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<p>Time series plot of the corresponding correlation (<b>a</b>) and the same time series with normalized values (<b>b</b>).</p>
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15 pages, 6995 KiB  
Review
The Influence of GLP1 on Body Weight and Glycemic Management in Patients with Diabetes—A Scientometric Investigation and Visualization Study
by Ileana Pantea, Angela Repanovici and Oana Andreescu
Medicina 2024, 60(11), 1761; https://doi.org/10.3390/medicina60111761 - 27 Oct 2024
Viewed by 548
Abstract
Diabetes medications can affect weight and cardiovascular health. Some medications can aid in weight management, while others may lead to weight gain. Patients must be monitored and receive appropriate care to manage weight and prevent cardiovascular complications. Despite advancements in diabetes treatments that [...] Read more.
Diabetes medications can affect weight and cardiovascular health. Some medications can aid in weight management, while others may lead to weight gain. Patients must be monitored and receive appropriate care to manage weight and prevent cardiovascular complications. Despite advancements in diabetes treatments that can influence weight and cardiovascular outcomes, ongoing research is necessary in this intricate field. Long-term effects, individual variations, and combination therapies are still subjects of uncertainty and ongoing investigation. The major objective of the research is to evaluate the impact of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) on body weight in diabetic patients through a scientometric assessment. Methodology: Research data were gathered from the Web of Science Core Collection (WoSCC) database by searching for the keywords “Body Weight”, dulaglutide, and semaglutide, identifying 60 relevant articles in the field. While there are advantages in managing diseases in which the cardiovascular system is implicated, there are also clinical considerations for personalized medicine and shared decision-making. The scientometric analysis of the articles revealed important insights into how dulaglutide and semaglutide impact weight management and their potential benefits for managing cardiovascular diseases in individuals with diabetes. Conclusions: Semaglutide shows superior outcomes compared to other commercially available GLP-1RAs, particularly in improving blood sugar control, lowering body weight, and addressing other cardio-metabolic risk factors in individuals with type 2 diabetes (T2DM). The findings suggest that GLP-1 RAs have the potential to provide cardiovascular protection by influencing various physiological factors such as blood pressure, pulse rate, glycated hemoglobin (HbA1c) levels, and the urinary albumin-to-creatinine ratio (RAC). The development and validation of the 4GI model provides a sophisticated tool for evaluating the complex interactions involved in diabetes treatments, offering insights into the mechanisms of action of various medications. Full article
(This article belongs to the Special Issue Public Health in the Post-pandemic Era)
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<p>Classification of GLP-1 RAs.</p>
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<p>The methodology’s key steps.</p>
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<p>Visualization of clusters.</p>
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<p>Research directions—results from the clusters analysis.</p>
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<p>Visualization of cluster one.</p>
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<p>Visualization of cluster two.</p>
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<p>Visualization of cluster three.</p>
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<p>Visualization of cluster four.</p>
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<p>Visualization of cluster five.</p>
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<p>Visualization of cluster six.</p>
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25 pages, 26385 KiB  
Article
An Innovative Tool for Monitoring Mangrove Forest Dynamics in Cuba Using Remote Sensing and WebGIS Technologies: SIGMEM
by Alexey Valero-Jorge, Raúl González-Lozano, Roberto González-De Zayas, Felipe Matos-Pupo, Rogert Sorí and Milica Stojanovic
Remote Sens. 2024, 16(20), 3802; https://doi.org/10.3390/rs16203802 - 12 Oct 2024
Viewed by 745
Abstract
The main objective of this work was to develop a viewer with web output, through which the changes experienced by the mangroves of the Gran Humedal del Norte de Ciego de Avila (GHNCA) can be evaluated from remote sensors, contributing to the understanding [...] Read more.
The main objective of this work was to develop a viewer with web output, through which the changes experienced by the mangroves of the Gran Humedal del Norte de Ciego de Avila (GHNCA) can be evaluated from remote sensors, contributing to the understanding of the spatiotemporal variability of their vegetative dynamics. The achievement of this objective is supported by the use of open-source technologies such as MapStore, GeoServer and Django, as well as Google Earth Engine, which combine to offer a robust and technologically independent solution to the problem. In this context, it was decided to adopt an action model aimed at automating the workflow steps related to data preprocessing, downloading, and publishing. A visualizer with web output (Geospatial System for Monitoring Mangrove Ecosystems or SIGMEM) is developed for the first time, evaluating changes in an area of central Cuba from different vegetation indices. The evaluation of the machine learning classifiers Random Forest and Naive Bayes for the automated mapping of mangroves highlighted the ability of Random Forest to discriminate between areas occupied by mangroves and other coverages with an Overall Accuracy (OA) of 94.11%, surpassing the 89.85% of Naive Bayes. The estimated net change based on the year 2020 of the areas determined during the classification process showed a decrease of 5138.17 ha in the year 2023 and 2831.76 ha in the year 2022. This tool will be fundamental for researchers, decision makers, and students, contributing to new research proposals and sustainable management of mangroves in Cuba and the Caribbean. Full article
(This article belongs to the Special Issue Remote Sensing: 15th Anniversary)
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<p>Location of the Gran Humedal del Norte de Ciego de Ávila (GHNCA), Cuba.</p>
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<p>General workflow for the development of the WebGis platform: SIGMEM.</p>
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<p>Spatial distribution of the reference points taken in the GHNCA. Green dots indicate mangrove class and red dots non-mangrove.</p>
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<p>Distribution of predictor variables used in the classification model grouped by classes (mangrove/non-mangrove). Selected Sentinel-2 spectral bands and spectral indices selected by the recursive variable elimination method.</p>
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<p>Diagram of the web architecture used for the development of the GeoServer.</p>
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<p>Estimated mangrove areas in the GHN in Ciego de Avila, Cuba emulating Sentinel-2 images. (<b>A</b>) 2020, (<b>B</b>) 2021, (<b>C</b>) 2022, and (<b>D</b>) 2023. Legend: the areas occupied by mangrove ecosystems in each of the years are shown in red; the limits of the GHN of Ciego de Avila are shown in blue dashed lines.</p>
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<p>Two-dimensional view of the workspace within the MapStore application. The red line represents the limit of the GHNCA.</p>
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<p>Three-dimensional view of the workspace within the MapStore application. The red line represents the limit of the GHNCA.</p>
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<p>Access to the metadata catalog of geospatial resources. The red line represents the limit of the GHNCA.</p>
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<p>Functionality for visual intercomparison of layers. The red line represents the limit of the GHNCA.</p>
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<p>Features for viewing and manipulating layer attributes. The red line represents the limit of the GHNCA.</p>
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<p>Vegetation Indices calculated in the GHN of Ciego de Avila, Cuba during the third quarter of the year 2023 emulating Sentinel-2 images. (<b>A</b>) NDVI, (<b>B</b>) EVI, (<b>C</b>) NDMI, and (<b>D</b>) CCCI.</p>
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13 pages, 453 KiB  
Review
Is Contrast-Enhanced Ultrasonography a New, Reliable Tool for Early-Graft-versus-Host Disease Diagnosis?
by Lavinia-Eugenia Lipan, Simona Ioanitescu, Alexandra-Oana Enache, Adrian Saftoiu and Alina Daniela Tanase
J. Clin. Med. 2024, 13(20), 6065; https://doi.org/10.3390/jcm13206065 - 11 Oct 2024
Viewed by 646
Abstract
Acute gastrointestinal graft-versus-host disease (GI aGVHD) is a significant and life-threatening complication in patients undergoing allogeneic stem cell transplantation (allo-SCT). Early diagnosis of GI aGVHD is crucial for improving patient outcomes, but it remains a challenge due to the condition’s nonspecific symptoms and [...] Read more.
Acute gastrointestinal graft-versus-host disease (GI aGVHD) is a significant and life-threatening complication in patients undergoing allogeneic stem cell transplantation (allo-SCT). Early diagnosis of GI aGVHD is crucial for improving patient outcomes, but it remains a challenge due to the condition’s nonspecific symptoms and the reliance on invasive diagnostic methods, such as biopsies and endoscopic procedures. In recent years, interest in non-invasive diagnostic techniques for graft-versus-host disease has increased, with contrast-enhanced ultrasound (CEUS) being one of them. For this reason, we aimed to examine the potential of ultrasound as a non-invasive, safe, and cost-effective alternative for the early detection and monitoring of GI aGVHD in this review. Our narrative review aims to describe the use of multimodal US that includes conventional US (B-mode and Doppler US) and advanced ultrasound techniques such as CEUS and CRTE for the non-invasive diagnosis of GI GVHD. We browsed several databases, including PubMed, Scopus, Web of Science, and Google Scholar. The search spanned 2000 to the present, focusing on articles written in English that reviewed the use of these imaging techniques in the context of GI GVHD. Following our research, we noticed that CEUS offers several advantages, including the real-time visualization of the gastrointestinal wall, assessment of blood flow, and detailed microvascular analysis—all achieved without the use of ionizing radiation. This feature makes CEUS an appealing option for repeated assessments, which are often necessary in monitoring the progression of GI aGVHD. When used in conjunction with conventional gastrointestinal ultrasound (GIUS), CEUS provides a more comprehensive view of the structural and functional changes occurring in the GI tract, potentially enhancing diagnostic accuracy and allowing for earlier intervention. In comparison to traditional diagnostic methods like tissue biopsy or CT scans, CEUS is less invasive, quicker to perform, and better tolerated by patients, especially those in fragile health following allo-SCT. Its non-invasive nature and ability to provide immediate imaging results make it a valuable tool for clinicians, particularly in settings where minimizing patient discomfort and risk is paramount. However, despite these advantages, there are still gaps in the literature regarding CEUS’s full diagnostic accuracy for GI aGVHD. Further research, including larger clinical trials and comparative studies, is needed to validate CEUS’s role in routine clinical practice and to establish standardized protocols for its use. Nonetheless, CEUS shows considerable potential to transform the diagnostic approach to GI aGVHD by improving early detection, reducing the need for invasive procedures, and ultimately enhancing treatment outcomes for affected patients. Full article
(This article belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
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<p>Review flowchart.</p>
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22 pages, 5226 KiB  
Article
Spatial Web-Interactive Impact Assessment Tool: Affordable Smart City Real Estate
by Sara Torabi Moghadam, Dana Al Mamlouk and Patrizia Lombardi
Sustainability 2024, 16(19), 8592; https://doi.org/10.3390/su16198592 - 3 Oct 2024
Viewed by 715
Abstract
The evaluation of smart affordable cities considering sustainable subsystems improves urban quality of life through efficient resource usage, reduced environmental impacts, and improved living conditions for residents. This study aims to develop an interactive and dynamic Web Geographic Information System (GIS) framework to [...] Read more.
The evaluation of smart affordable cities considering sustainable subsystems improves urban quality of life through efficient resource usage, reduced environmental impacts, and improved living conditions for residents. This study aims to develop an interactive and dynamic Web Geographic Information System (GIS) framework to facilitate decision-making processes during the design phase while including third parties and stakeholders using a spatial interactive impact assessment approach. The methodology follows a quantitative research method based on delivering a tool that could be replicated in other contexts. This tool assesses the impact of smart scenarios to support affordable city planning through selecting Key Performance Indicators (KPIs). This tool was applied to Brazilian large-scale affordable housing within a smart city project. Based on this study, the conclusion reports some research limitations and the possibility of creating a beta version of the tool for future development. The findings show that this Web-GIS framework enhances stakeholder engagement and the effectiveness of decision making in developing sustainable urban planning. Full article
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<p>Methodological flowchart.</p>
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<p>Data preparation diagram for Tableau (authors’ elaboration).</p>
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<p>Baseline map.</p>
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<p>Developed Web-GIS tool dashboard explanation.</p>
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<p>Scenarios for different indicators in developed Web-GIS tool.</p>
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21 pages, 3719 KiB  
Review
Evaluating Multi-Criteria Decision-Making Methods for Sustainable Management of Forest Ecosystems: A Systematic Review
by Cokou Patrice Kpadé, Lota D. Tamini, Steeve Pepin, Damase P. Khasa, Younes Abbas and Mohammed S. Lamhamedi
Forests 2024, 15(10), 1728; https://doi.org/10.3390/f15101728 - 29 Sep 2024
Viewed by 1029
Abstract
Multi-criteria decision-making (MCDM) methods provide a framework for addressing sustainable forest management challenges, especially under climate change. This study offers a systematic review of MCDM applications in forest management from January 2010 to March 2024. Descriptive statistics were employed to analyze trends in [...] Read more.
Multi-criteria decision-making (MCDM) methods provide a framework for addressing sustainable forest management challenges, especially under climate change. This study offers a systematic review of MCDM applications in forest management from January 2010 to March 2024. Descriptive statistics were employed to analyze trends in MCDM use and geographic distribution. Thematic content analysis investigated the appearance of MCDM indicators supplemented by Natural Language Processing (NLP). Factorial Correspondence Analysis (FCA) explored correlations between models and publication outlets. We systematically searched Web of Science (WoS), Scopus, Google Scholar, Semantic Scholar, CrossRef, and OpenAlex using terms such as ‘MCDM’, ‘forest management’, and ‘decision support’. We found that the Analytical Hierarchy Process (AHP) and the Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS) were the most commonly used methods, followed by the Preference Ranking Organization Method for Enrichment Evaluation (PROMETHEE), the Analytic Network Process (ANP), GIS, and Goal Programming (GP). Adoption varied across regions, with advanced models such as AHP and GIS less frequently used in developing countries due to technological constraints. These findings highlight emerging trends and gaps in MCDM application, particularly for argan forests, emphasizing the need for context-specific frameworks to support sustainable management in the face of climate change. Full article
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<p>Systematic literature review process based on ROSES protocol; adapted from Ishtiaque [<a href="#B49-forests-15-01728" class="html-bibr">49</a>].</p>
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<p>Single (one MCDM model only) versus multiple (&gt;1 MCDM model) approaches adopted in the reviewed studies (<span class="html-italic">n</span> = 46).</p>
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<p>Radar showing the frequency of MCDM models.</p>
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<p>Relative frequency comparison of MCDM models in forestry over time (<b>A</b>–<b>F</b>).</p>
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<p>Relative frequency comparison of most model combinations of reviews over time.</p>
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<p>Hierarchy chart showing the number of countries and models used in forestry.</p>
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<p>Factorial correspondence analysis between models used in forestry and publishing journals. Legend: Ejud: Expert_judgment; Spr: Scoring_process; PFr: Pareto_Frontier; PROM: PROMETHEE; GMCDM: GIS-MCDM; Dme: Delphi_method; DEM: DEMATEL; Flogn: Fuzzy_logic_norm; GISM: GIS_SMCD; CJFR: Canadian Journal of Forest Research; ECOL: Ecological Indicators; JFOR: Journal of Forest Planning; ISAH: ISAHP Proceedings; FORp: Forest Policy and Economics; ENVI: Environmental Monitoring and Assessment; LIFE: Life Science Journal; FORt: Forests; JENV: Journal of Environmental Planning and Management; ANFR: Annals of Forest Research; COMP: Computers and Electronics in Agriculture; IOPC: IOP Conference Series: Materials Science and Engineering; SUST: Sustainability; SUMA: Sumarski List; IJEG: International Journal of Environment and Geoinformatics; ICIE: International Conference on Industrial Engineering and Management; IJSA: International Journal of Sustainable Agricultural Management and Informatics; JINN: Journal of Innovation &amp; Knowledge; FIRE: Fire; JCLE: Journal of Cleaner Production; JPLA: Jurnal Ilmiah PLATAX; APPL: Applied Geography; FORm: Forest Ecology and Management; E3SW: E3S Web of Conferences; SCIR: Scientific Reports; SSRN: SSRN Electronic Journal; RESQ: Research Square; CEFJ: Central European Forestry Journal; ECOI: Ecology of Iranian Forests; GEOS: Geo-spatial Information Science; F1: First dimension of FCA, and F2: Second dimension of FCA.</p>
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<p>Radar chart depicting the average number of indicators used in empirical studies by models.</p>
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25 pages, 10814 KiB  
Article
Three-Dimensional Web-Based Client Presentation of Integrated BIM and GIS for Smart Cities
by Abdullah Varlık and İsmail Dursun
Buildings 2024, 14(9), 3021; https://doi.org/10.3390/buildings14093021 - 23 Sep 2024
Viewed by 1201
Abstract
Smart cities use technological solutions to reduce the drawbacks of urban living. The importance of BIM and GIS integration has increased with the popularity of smart city and 3D city concepts in recent years. In addition to 3D city models, Building Information Modeling [...] Read more.
Smart cities use technological solutions to reduce the drawbacks of urban living. The importance of BIM and GIS integration has increased with the popularity of smart city and 3D city concepts in recent years. In addition to 3D city models, Building Information Modeling (BIM) is an essential element of smart cities. The 3D city model web client in this study displays three-dimensional (3D) city models created using photogrammetric techniques, BIM, and campus infrastructure projects. The comparison and integration of the aforementioned systems were evaluated. A web-based 3D client framework and implementation for combined BIM and 3D city models are the goals of the submitted work. The Web is a very challenging platform for 3D data presentation. The Cesium engine based on HTML5 and WebGL is an open-source creation and the virtualcityMAP application using the Cesium infrastructure was used in this study. Full article
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<p>LoD representation is defined by CityGML 2.0 and CityGML 3.0 [<a href="#B16-buildings-14-03021" class="html-bibr">16</a>,<a href="#B17-buildings-14-03021" class="html-bibr">17</a>].</p>
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<p>Relationship between the LoD and the degree of representativeness [<a href="#B22-buildings-14-03021" class="html-bibr">22</a>].</p>
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<p>Snapshot of a building modeled in IFC (right side) and CityGML (left side) [<a href="#B26-buildings-14-03021" class="html-bibr">26</a>].</p>
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<p>Research route of the full level of detail (LoD) specification for 3D building models. IFC, industry foundation classes; ILoD, indoor LoD; OLoD, outdoor LoD [<a href="#B18-buildings-14-03021" class="html-bibr">18</a>].</p>
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<p>Semantic mapping of IFC and CityGML classes (yellow outline indicates IFC classes and green outline indicates CityGML classes. Classes in boxes without black outlines do not carry geometric information) [<a href="#B39-buildings-14-03021" class="html-bibr">39</a>].</p>
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<p>Working area.</p>
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<p>BIM model generated through CAD-to-BIM conversion.</p>
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<p>(<b>a</b>) SBIF UAV data; (<b>b</b>) campus orthophoto.</p>
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<p>SBIF LIDAR point cloud.</p>
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<p>Scan-to-BIM model.</p>
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<p>Integration of CityGML and IFC. Note: “*” UML notation used to representation the cardinal relationship among CityGML classes that shows the number of occurrence or possibilities and an intermediately model is shown inside the red box.</p>
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<p>3D city model/BIM integration model.</p>
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<p>Georeferencing.</p>
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<p>IFC to CityGML transformation FME workbench [<a href="#B70-buildings-14-03021" class="html-bibr">70</a>].</p>
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<p>Used CityGML structure encoded in GML.</p>
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<p>Main data.</p>
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<p>Supplementary data.</p>
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20 pages, 2989 KiB  
Article
A Review of Pakistan’s National Spatial Data Infrastructure Using Multiple Assessment Frameworks
by Munir Ahmad, Asmat Ali, Muhammad Nawaz, Farha Sattar and Hammad Hussain
ISPRS Int. J. Geo-Inf. 2024, 13(9), 328; https://doi.org/10.3390/ijgi13090328 - 14 Sep 2024
Viewed by 831
Abstract
Efforts to establish Pakistan’s National Spatial Data Infrastructure (NSDI) have been underway for the past 15 years, and therefore it is necessary to gauge the current progress to channelize efforts into areas that need improvement. This article assessed Pakistan’s NSDI implementation efforts through [...] Read more.
Efforts to establish Pakistan’s National Spatial Data Infrastructure (NSDI) have been underway for the past 15 years, and therefore it is necessary to gauge the current progress to channelize efforts into areas that need improvement. This article assessed Pakistan’s NSDI implementation efforts through well-established approaches, including the SDI readiness model, organizational aspects, and state of play. The data were collected from Spatial Data Infrastructure (SDI) and Geographic Information System (GIS) experts. The findings underscored challenges related to human resources, SDI education/culture, long-term vision, lack of awareness of geoinformation (GI), sustainable funding, metadata availability, online geospatial services, and geospatial standards hindering NSDI development in Pakistan. However, certain factors exhibit favorable standings, such as the legal framework for NSDI establishment, web connectivity, geospatial software availability, the unavailability of core spatial datasets, and institutional leadership. Thus, to enhance the development of NSDI in Pakistan, recommendations include bolstering financial and human resources, improving online geospatial presence, and fostering a long-term vision for NSDI. Full article
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<p>Scores of Pakistan’s NSDI readiness indices.</p>
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<p>Score of organizational index.</p>
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<p>Score of information index.</p>
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<p>Score of human resources index.</p>
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<p>Score of technology index.</p>
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<p>Score of financial resources index.</p>
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<p>Scores of Pakistan’s NSDI readiness indicators.</p>
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<p>Summarized results of 05 indicators of the state-of-play approach.</p>
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20 pages, 27362 KiB  
Article
SMARTerra, a High-Resolution Decision Support System for Monitoring Plant Pests and Diseases
by Michele Fiori, Giuliano Fois, Marco Secondo Gerardi, Fabio Maggio, Carlo Milesi and Andrea Pinna
Appl. Sci. 2024, 14(18), 8275; https://doi.org/10.3390/app14188275 - 13 Sep 2024
Viewed by 617
Abstract
The prediction and monitoring of plant diseases and pests are key activities in agriculture. These activities enable growers to take preventive measures to reduce the spread of diseases and harmful insects. Consequently, they reduce crop loss, make pesticide and resource use more efficient, [...] Read more.
The prediction and monitoring of plant diseases and pests are key activities in agriculture. These activities enable growers to take preventive measures to reduce the spread of diseases and harmful insects. Consequently, they reduce crop loss, make pesticide and resource use more efficient, and preserve plant health, contributing to environmental sustainability. We illustrate the SMARTerra decision support system, which processes daily measured and predicted weather data, spatially interpolating them at high resolution across the entire Sardinia region. From these data, SMARTerra generates risk predictions for plant pests and diseases. Currently, models for predicting the risk of rice blast disease and the hatching of locust eggs are implemented in the infrastructure. The web interface of the SMARTerra platform allows users to visualize detailed risk maps and promptly take preventive measures. A simple notification system is also implemented to directly alert emergency responders. Model outputs by the SMARTerra infrastructure are comparable with results from in-field observations produced by the LAORE Regional Agency. The infrastructure provides a database for storing the time series and risk maps generated, which can be used by agencies and researchers to conduct further analysis. Full article
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<p>A schematic description of the back-end and front-end of the SMARTerra decision support system.</p>
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<p>The digital elevation model (DEM) of Sardinia, with the island’s main rice-growing areas (<b>left</b>). The DEM was obtained by processing <math display="inline"><semantics> <mrow> <mn>10</mn> <mo> </mo> <mi mathvariant="normal">m</mi> </mrow> </semantics></math> resolution rasters downloaded from the geoportal of the region of Sardinia [<a href="#B14-applsci-14-08275" class="html-bibr">14</a>]. On the (<b>right</b>), the locations of the meteorological stations of the Regional Meteorological Network (RUR) are shown in yellow, and the nodes of the grid points for which the BOLAM model provides weather forecasts are shown in white.</p>
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<p>A schematic description of the InfluxDB time-series-oriented database storing the weather measurements from the RUR network and BOLAM forecasts. After preprocessing, the data are put into the database and organized into measurements and fields. Then, the data become available for the interpolation techniques by query via API.</p>
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<p>Temperature distribution for a selected geographic window at a specific day and time. Enabling the “Station” flag displays all stations (shown as blue dots) within the window. Detailed variations of the selected variable are shown for each station (dark popup), along with the relative trend of the value from the nearest BOLAM grid point (blue popup). The white dots represent the location of the 4 nodes of the BOLAM model closest to the selected station.</p>
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<p>Detail of the rice blast (“brusone”) risk map on a given day, highlighting the paddy field areas. The dark popup allows users to view specific information about the selected parcel, including the name of the farm, technical features like area, the rice cultivar, and other relevant details.</p>
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<p>Daily maximum temperature (<b>left</b>) and daily rainfall accumulation (<b>right</b>) spatially interpolated from measured data with the KED technique.</p>
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<p>Thumbnails from the PDF report. From (<b>top left</b>) to (<b>bottom right</b>), the hourly mean temperature, mean relative humidity and rainfall from the measured and forecast data, the daily maximum and mean temperature and rainfall from the measured data, the risk indices and alert levels for the rice blast disease, and the threshold dates and accumulation totals for the locust egg hatching prediction.</p>
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<p>Risk indices (<b>top</b>, <b>bottom left</b>) and alert levels (<b>bottom right</b>) maps for the rice blast disease obtained from interpolated measured and forecast weather data. See <a href="#sec2dot2dot5-applsci-14-08275" class="html-sec">Section 2.2.5</a> for details.</p>
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<p>The cumulative sum of degree days (<b>left</b>), starting for each pixel of the map once the rain accumulation threshold <math display="inline"><semantics> <mrow> <msub> <mi>R</mi> <mi>th</mi> </msub> <mo>=</mo> <mn>100</mn> <mo> </mo> <mrow> <mi mathvariant="normal">m</mi> <mi mathvariant="normal">m</mi> </mrow> </mrow> </semantics></math> has been reached, and the predicted dates for locust egg hatching (<b>right</b>). The white areas indicate regions where the summation of <math display="inline"><semantics> <mrow> <msub> <mi>D</mi> <mi>th</mi> </msub> <mo>=</mo> <mn>200</mn> <mo> </mo> <mrow> <mo>°</mo> <mi mathvariant="normal">C</mi> </mrow> </mrow> </semantics></math> degree days has not yet occurred. Compare with the former map, where the darkest red areas correspond to regions where the summation of degree days is below the threshold <math display="inline"><semantics> <msub> <mi>D</mi> <mi>th</mi> </msub> </semantics></math>. See <a href="#sec2dot2dot6-applsci-14-08275" class="html-sec">Section 2.2.6</a> for details.</p>
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<p>Comparison of observed and predicted alert levels for rice blast disease in the Oristano rice districts. Observed (<b>top left</b>) and predicted (<b>top right</b>) alert levels for 17 July 2023. Observed (<b>bottom left</b>) and predicted (<b>bottom right</b>) alert levels for 18 July 2023.</p>
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<p>Spatial distribution of <math display="inline"><semantics> <msub> <mo>Δ</mo> <mi>d</mi> </msub> </semantics></math> for egg hatching predicted by the default (literature) model (<b>left</b>) and a slightly modified model (<b>right</b>), both with a superimposed OpenStreetMap layer (<b>top</b>), a map of the dates for <math display="inline"><semantics> <msub> <mi>day</mi> <mn>2</mn> </msub> </semantics></math> when the rain threshold <math display="inline"><semantics> <msub> <mi>R</mi> <mi>th</mi> </msub> </semantics></math> is reached and the accumulation of degree days starts (<b>middle</b>), and a map representing <math display="inline"><semantics> <msub> <mi>day</mi> <mn>3</mn> </msub> </semantics></math>, the predicted dates of the hatching of locust eggs (<b>bottom</b>). The region of interest is partitioned into hexagons, each of which is assigned a color according to the average of the <math display="inline"><semantics> <msub> <mo>Δ</mo> <mi>d</mi> </msub> </semantics></math> values of the records within the area of the hexagon itself.</p>
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16 pages, 3693 KiB  
Article
Sustainable Waste Governance Framework via Web-GIS: Kadikoy Case
by Melda Karademir and Buket Ayşegül Özbakır Acımert
Sustainability 2024, 16(16), 7171; https://doi.org/10.3390/su16167171 - 21 Aug 2024
Viewed by 717
Abstract
Waste management, one of the fundamental problems of today, is at the center of sustainability discussions. The failure to adopt a holistic and participatory approach in traditional waste management highlights the need to develop new approaches. The main purpose of this research is [...] Read more.
Waste management, one of the fundamental problems of today, is at the center of sustainability discussions. The failure to adopt a holistic and participatory approach in traditional waste management highlights the need to develop new approaches. The main purpose of this research is to present the basic components of a Web-GIS-based platform design for sustainable waste governance. The presented framework emphasizes that waste management is not a problem of local or central government and that holistic sustainable waste governance can be achieved with the participation of all relevant stakeholders. The Kadikoy district of Istanbul, a metropolitan city, was selected as the study area. Information was collected from the study area with quantitative and qualitative analysis methods. The results obtained with fieldwork and survey data show that there is a need for a location-based platform that allows relevant stakeholders to see the current waste management workflow, enter data themselves, and provide feedback. The Web-GIS-based platform proposed in this article to meet this need is an important step in ensuring sustainable waste governance. In the article, a Web-GIS-based platform has been developed to ensure the sustainable waste governance of commercial enterprises for local governments. Full article
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<p>General structure of Web-GIS.</p>
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<p>Web-GIS platform on sustainable waste governance of commercial enterprises for local government.</p>
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<p>Kadikoy district and its neighborhoods.</p>
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<p>SDG scorecard of waste governance for Kadikoy Municipality.</p>
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<p>Types of waste-collecting vehicles in Kadikoy via Web-GIS.</p>
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<p>Results sample of questionnaire via Web-GIS.</p>
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<p>Distribution of recyclable bins and commercial enterprises in Kadikoy via Web-GIS.</p>
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21 pages, 6051 KiB  
Systematic Review
The Role of Akkermansia muciniphila on Improving Gut and Metabolic Health Modulation: A Meta-Analysis of Preclinical Mouse Model Studies
by Leila Khalili, Gwoncheol Park, Ravinder Nagpal and Gloria Salazar
Microorganisms 2024, 12(8), 1627; https://doi.org/10.3390/microorganisms12081627 - 9 Aug 2024
Cited by 1 | Viewed by 2234
Abstract
Akkermansia muciniphila (A. muciniphila) and its derivatives, including extracellular vesicles (EVs) and outer membrane proteins, are recognized for enhancing intestinal balance and metabolic health. However, the mechanisms of Akkermansia muciniphila’s action and its effects on the microbiome are not well [...] Read more.
Akkermansia muciniphila (A. muciniphila) and its derivatives, including extracellular vesicles (EVs) and outer membrane proteins, are recognized for enhancing intestinal balance and metabolic health. However, the mechanisms of Akkermansia muciniphila’s action and its effects on the microbiome are not well understood. In this study, we examined the influence of A. muciniphila and its derivatives on gastrointestinal (GI) and metabolic disorders through a meta-analysis of studies conducted on mouse models. A total of 39 eligible studies were identified through targeted searches on PubMed, Web of Science, Science Direct, and Embase until May 2024. A. muciniphila (alive or heat-killed) and its derivatives positively affected systemic and gut inflammation, liver enzyme level, glycemic response, and lipid profiles. The intervention increased the expression of tight-junction proteins in the gut, improving gut permeability in mouse models of GI and metabolic disorders. Regarding body weight, A. muciniphila and its derivatives prevented weight loss in animals with GI disorders while reducing body weight in mice with metabolic disorders. Sub-group analysis indicated that live bacteria had a more substantial effect on most analyzed biomarkers. Gut microbiome analysis using live A. muciniphila identified a co-occurrence cluster, including Desulfovibrio, Family XIII AD3011 group, and Candidatus Saccharimonas. Thus, enhancing the intestinal abundance of A. muciniphila and its gut microbial clusters may provide more robust health benefits for cardiometabolic, and age-related diseases compared with A. muciniphila alone. The mechanistic insight elucidated here will pave the way for further exploration and potential translational applications in human health. Full article
(This article belongs to the Special Issue Advances in Host-Gut Microbiota)
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<p>The PRISMA flowchart of the approach employed in this study. The relevant studies were identified through comprehensive database searches in PubMed, Embase, Web of Science, and Science Direct up to May 2024. The search criteria encompassed studies exploring the impact of <span class="html-italic">A. muciniphila</span> on gut microbiota and metabolic response, specifically in mice models, which are used to study metabolic and GI disorders.</p>
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<p>Effect of <span class="html-italic">A. muciniphila</span> on systemic and gut inflammation [<a href="#B15-microorganisms-12-01627" class="html-bibr">15</a>,<a href="#B17-microorganisms-12-01627" class="html-bibr">17</a>,<a href="#B25-microorganisms-12-01627" class="html-bibr">25</a>,<a href="#B26-microorganisms-12-01627" class="html-bibr">26</a>,<a href="#B29-microorganisms-12-01627" class="html-bibr">29</a>,<a href="#B30-microorganisms-12-01627" class="html-bibr">30</a>,<a href="#B31-microorganisms-12-01627" class="html-bibr">31</a>,<a href="#B32-microorganisms-12-01627" class="html-bibr">32</a>,<a href="#B33-microorganisms-12-01627" class="html-bibr">33</a>,<a href="#B35-microorganisms-12-01627" class="html-bibr">35</a>,<a href="#B37-microorganisms-12-01627" class="html-bibr">37</a>,<a href="#B38-microorganisms-12-01627" class="html-bibr">38</a>,<a href="#B39-microorganisms-12-01627" class="html-bibr">39</a>,<a href="#B41-microorganisms-12-01627" class="html-bibr">41</a>,<a href="#B42-microorganisms-12-01627" class="html-bibr">42</a>,<a href="#B43-microorganisms-12-01627" class="html-bibr">43</a>,<a href="#B46-microorganisms-12-01627" class="html-bibr">46</a>,<a href="#B47-microorganisms-12-01627" class="html-bibr">47</a>,<a href="#B50-microorganisms-12-01627" class="html-bibr">50</a>,<a href="#B52-microorganisms-12-01627" class="html-bibr">52</a>,<a href="#B56-microorganisms-12-01627" class="html-bibr">56</a>,<a href="#B57-microorganisms-12-01627" class="html-bibr">57</a>,<a href="#B58-microorganisms-12-01627" class="html-bibr">58</a>,<a href="#B59-microorganisms-12-01627" class="html-bibr">59</a>]. Forest plot of individual SMD of serum inflammatory markers (TNFα, IL6, IL10, and LPS) and expression of inflammatory factors (TNFα, IL6, and IL10) in the gut of aging mice and mice with GI and metabolic disorders. A green diamond indicates significance, while the white diamond indicates not statistical differences.</p>
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<p>Effect of <span class="html-italic">A. muciniphila</span> on gut epithelial health markers [<a href="#B15-microorganisms-12-01627" class="html-bibr">15</a>,<a href="#B17-microorganisms-12-01627" class="html-bibr">17</a>,<a href="#B23-microorganisms-12-01627" class="html-bibr">23</a>,<a href="#B26-microorganisms-12-01627" class="html-bibr">26</a>,<a href="#B27-microorganisms-12-01627" class="html-bibr">27</a>,<a href="#B28-microorganisms-12-01627" class="html-bibr">28</a>,<a href="#B29-microorganisms-12-01627" class="html-bibr">29</a>,<a href="#B30-microorganisms-12-01627" class="html-bibr">30</a>,<a href="#B31-microorganisms-12-01627" class="html-bibr">31</a>,<a href="#B32-microorganisms-12-01627" class="html-bibr">32</a>,<a href="#B34-microorganisms-12-01627" class="html-bibr">34</a>,<a href="#B35-microorganisms-12-01627" class="html-bibr">35</a>,<a href="#B36-microorganisms-12-01627" class="html-bibr">36</a>,<a href="#B37-microorganisms-12-01627" class="html-bibr">37</a>,<a href="#B38-microorganisms-12-01627" class="html-bibr">38</a>,<a href="#B41-microorganisms-12-01627" class="html-bibr">41</a>,<a href="#B43-microorganisms-12-01627" class="html-bibr">43</a>,<a href="#B44-microorganisms-12-01627" class="html-bibr">44</a>,<a href="#B50-microorganisms-12-01627" class="html-bibr">50</a>,<a href="#B52-microorganisms-12-01627" class="html-bibr">52</a>,<a href="#B54-microorganisms-12-01627" class="html-bibr">54</a>,<a href="#B56-microorganisms-12-01627" class="html-bibr">56</a>,<a href="#B57-microorganisms-12-01627" class="html-bibr">57</a>,<a href="#B58-microorganisms-12-01627" class="html-bibr">58</a>,<a href="#B59-microorganisms-12-01627" class="html-bibr">59</a>]. Forest plot of individual SMD of colon length, mucus thickness, and tight-junction expression (protein and mRNA) in the gut of aging mice and mice with GI and metabolic disorders. A green diamond indicates significance, while the white diamond indicates not statistical differences.</p>
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<p>Effect of <span class="html-italic">A. muciniphila</span> on metabolic profiles and liver health [<a href="#B15-microorganisms-12-01627" class="html-bibr">15</a>,<a href="#B17-microorganisms-12-01627" class="html-bibr">17</a>,<a href="#B40-microorganisms-12-01627" class="html-bibr">40</a>,<a href="#B41-microorganisms-12-01627" class="html-bibr">41</a>,<a href="#B42-microorganisms-12-01627" class="html-bibr">42</a>,<a href="#B43-microorganisms-12-01627" class="html-bibr">43</a>,<a href="#B44-microorganisms-12-01627" class="html-bibr">44</a>,<a href="#B45-microorganisms-12-01627" class="html-bibr">45</a>,<a href="#B46-microorganisms-12-01627" class="html-bibr">46</a>,<a href="#B48-microorganisms-12-01627" class="html-bibr">48</a>,<a href="#B49-microorganisms-12-01627" class="html-bibr">49</a>,<a href="#B50-microorganisms-12-01627" class="html-bibr">50</a>,<a href="#B51-microorganisms-12-01627" class="html-bibr">51</a>,<a href="#B53-microorganisms-12-01627" class="html-bibr">53</a>,<a href="#B55-microorganisms-12-01627" class="html-bibr">55</a>,<a href="#B57-microorganisms-12-01627" class="html-bibr">57</a>,<a href="#B58-microorganisms-12-01627" class="html-bibr">58</a>,<a href="#B59-microorganisms-12-01627" class="html-bibr">59</a>]. Forest plot of individual SMD of glycemic control (blood glucose, insulin level, and HOMA.IR), lipid profile (TG and cholesterol), and liver enzymes (ALT and AST) of mice with metabolic disorders. A green diamond indicates significance.</p>
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<p>Effect of <span class="html-italic">A. muciniphila</span> on body weight [<a href="#B17-microorganisms-12-01627" class="html-bibr">17</a>,<a href="#B26-microorganisms-12-01627" class="html-bibr">26</a>,<a href="#B31-microorganisms-12-01627" class="html-bibr">31</a>,<a href="#B36-microorganisms-12-01627" class="html-bibr">36</a>,<a href="#B38-microorganisms-12-01627" class="html-bibr">38</a>,<a href="#B40-microorganisms-12-01627" class="html-bibr">40</a>,<a href="#B44-microorganisms-12-01627" class="html-bibr">44</a>,<a href="#B48-microorganisms-12-01627" class="html-bibr">48</a>,<a href="#B50-microorganisms-12-01627" class="html-bibr">50</a>,<a href="#B55-microorganisms-12-01627" class="html-bibr">55</a>,<a href="#B56-microorganisms-12-01627" class="html-bibr">56</a>,<a href="#B57-microorganisms-12-01627" class="html-bibr">57</a>,<a href="#B58-microorganisms-12-01627" class="html-bibr">58</a>]. Forest plot of individual SMD of body weight of mice with GI and metabolic disorders. A green diamond indicates significance.</p>
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<p>The treatment with <span class="html-italic">A. muciniphila</span> induces alterations in microbial co-regulation ecological niches. (<b>A</b>) Microbial alpha-diversity. Microbial composition at (<b>B</b>) phylum, (<b>C</b>) family, and (<b>D</b>) genus level. (<b>E</b>) The top 15 genera are more abundant in each group (ALDEx2). (<b>F</b>) Significantly correlated genus with <span class="html-italic">A. muciniphila</span> (Spearman correlation coefficient (ρ) &gt; 0.3). Correlational network between genera in (<b>G</b>) CTL and (<b>H</b>) AKK group. Each node represents one genus, and only significant links are shown (Spearman coefficient (ρ) &gt; 0.7, Benjamini–Hochberg corrected <span class="html-italic">p</span>-value &lt; 0.05). CTL: control group; AKK: <span class="html-italic">A. muciniphila</span>-treated group.</p>
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<p>Relative abundance of taxa showing co-occurrence association with <span class="html-italic">Akkermansia</span> (Akk) in network analysis of the AKK group. Comparison of the relative abundance of (<b>A</b>) <span class="html-italic">Desulfovibrio</span>, (<b>B</b>) <span class="html-italic">Candidadus Saccharimonas</span>, and (<b>C</b>) <span class="html-italic">Family XIII AD3011</span> group (<span class="html-italic">Anaerovoracaceae</span> family) between treatment groups (CTL and AKK), Akk non-detected (Akk-; <span class="html-italic">n</span> = 43) and Akk detected (Akk+; <span class="html-italic">n</span> = 33) samples. (<b>D</b>–<b>F</b>) Akk detected and non-detected samples within treatment groups (CTL/Akk− <span class="html-italic">n</span> = 21, CTL/Akk+ <span class="html-italic">n</span> = 14, AKK/Akk− <span class="html-italic">n</span> = 22, AKK/Akk+ <span class="html-italic">n</span> = 19). <span class="html-italic">p</span>-values were calculated using the Mann–Whitney U test (Wilcoxon rank sum test). Bar plots are presented as mean ± SE. * <span class="html-italic">p</span> &lt; 0.05; *** <span class="html-italic">p</span> &lt; 0.001.</p>
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<p>Model of the proposed mechanism by which <span class="html-italic">A. muciniphila</span> improves host health. Oral administration of <span class="html-italic">A. muciniphila</span> remodels the gut microbiota, increasing the abundance of <span class="html-italic">Desulfovibrio</span>, <span class="html-italic">Candidatus Saccharimonas</span>, and <span class="html-italic">Family_XIII_AD3011</span>. <span class="html-italic">Desulfovibrio</span> produces H<sub>2</sub>S, which inhibits inflammation and protects the cardiovascular system. However, H<sub>2</sub>S overproduction has been reported in Parkinson’s disease (PD) patients. <span class="html-italic">Candidatus Saccharimonas</span> produces lactate and acetate and reduces inflammation in macrophages. Less is known of the function of <span class="html-italic">Family_XIII_AD3011</span>. These changes were associated with reduced intestinal inflammation and improved gut permeability, likely through the activation of TLR and the inhibition of NF-kB. Upregulation of intestinal IL10 likely reduces pro-inflammatory cytokines and upregulates tight junction proteins. In circulation, <span class="html-italic">A. muciniphila</span> reduced inflammation (TNFα, IL6), cholesterol, TG, and LPS while increasing HDL and improving glucose control. In the liver, <span class="html-italic">A. muciniphila</span>, reduced ALT, AST, and IL1β. The known activation of FXR (dotted line) by <span class="html-italic">A. muciniphila</span> may explain the reduction in TG and improved glucose sensitivity. FXR activation, along with the reduction in cholesterol, is also expected to reduce bile acid and fatty acid (FA) synthesis in the liver. Blue and red arrowheads indicate reduced and increased expression, respectively. The model was generated using BioRender.</p>
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