Search Results (22)

Background: In the absence of Helicobacter pylori (HP) infection, a characteristic gastric mucus adhesion may appear during the use of vonoprazan. We named this novel characteristic mucus “web-like mucus” (WLM). This study aimed to determine the incidence and risk factors for WLM. Methods: Between January 2017 and January 2022, 5665 patients were enrolled in this study. The patients were divided into a proton-pump inhibitor (PPI)-prescribed group (n = 2000), a vonoprazan-prescribed group (n = 268), and a no-PPI/vonoprazan-prescribed (n = 3397) group, and the presence of WLM was examined. After excluding four patients with autoimmune gastritis, the remaining 264 patients in the vonoprazan group were divided into WLM and non-WLM groups, and their clinical features were analyzed. Results: A total of 55 (21%) patients had WLM, all in the vonoprazan-prescribed group. There were no significant differences in factors such as, sex, age, chronic kidney disease, diabetes mellitus, HP eradication history, smoking, or alcohol consumption between the WLM and non-WLM groups. The median duration from the start of vonoprazan administration to the endoscopic detection of WLM was 2 (1–24) months. Conclusions: WLM appears to be a characteristic feature in patients treated with vonoprazan. Full article

We report on the effect of a hydrocarbon (n-dodecane) on the rheological properties and shapes of the hybrid wormlike micelles (WLMs) of a surfactant potassium oleate with an embedded polymer poly(4-vinylpyridine). With and without hydrocarbon solutions, the hybrid micelles exhibit the same values of viscosity at shear rates typical for hydraulic fracturing (HF) tests, as solutions of polymer-free WLMs. Therefore, similar to WLMs of surfactants, they could be applied as thickeners in HF fluids without breakers. At the same time, in the presence of n-dodecane, the hybrid micelles have much higher drag-reducing efficiency compared to microemulsions formed in polymer-free systems since they form “beads-on-string” structures according to results obtained using cryo-transmission electron microscopy (cryo-TEM), dynamic-light scattering (DLS), and small-angle X-ray scattering (SAXS). Consequently, they could also act as drag-reducing agents in the pipeline transport of recovered oil. Such a unique multi-functional additive to a fracturing fluid, which permits its concurrent use in oil production and oil transportation, has not been proposed before. Full article

Mass loss is one of the key parameters that determine stellar evolution. Despite the progress we have achieved over the last decades we still cannot match the observational derived values with theoretical predictions. Even worse, there are certain phases, such as the B[e] supergiants (B[e]SGs) and the Luminous Blue Variables (LBVs), where significant mass is lost through episodic or outburst activity. This leads to various structures forming around them that permit dust formation, making these objects bright IR sources. The ASSESS project aims to determine the role of episodic mass in the evolution of massive stars, by examining large numbers of cool and hot objects (such as B[e]SGs/LBVs). For this purpose, we initiated a large observation campaign to obtain spectroscopic data for ∼1000 IR-selected sources in 27 nearby galaxies. Within this project we successfully identified seven B[e] supergiants (one candidate) and four Luminous Blue Variables of which six and two, respectively, are new discoveries. We used spectroscopic, photometric, and light curve information to better constrain the nature of the reported objects. We particularly noted the presence of B[e]SGs at metallicity environments as low as 0.14 Z${}_{\odot }$. Full article

pH-responsive viscoelastic fluids are often achieved by adding hydrotropes into surfactant solutions. However, the use of metal salts to prepare pH-responsive viscoelastic fluids has been less documented. Herein, a pH-responsive viscoelastic fluid was developed by blending an ultra-long-chain tertiary amine, N-erucamidopropyl-N, N-dimethylamine (UC₂₂AMPM), with metal salts (i.e., AlCl₃, CrCl₃, and FeCl₃). The effects of the surfactant/metal salt mixing ratio and the type of metal ions on the viscoelasticity and phase behavior of fluids were systematically examined by appearance observation and rheometry. To elucidate the role of metal ions, the rheological properties between AlCl₃− and HCl−UC₂₂AMPM systems were compared. Results showed the above metal salt evoked the low-viscosity UC₂₂AMPM dispersions to form viscoelastic solutions. Similar to HCl, AlCl₃ could also protonate the UC₂₂AMPM into a cationic surfactant, forming wormlike micelles (WLMs). Notably, much stronger viscoelastic behavior was evidenced in the UC₂₂AMPM−AlCl₃ systems because the Al³⁺ as metal chelators coordinated with WLMs, promoting the increment of viscosity. By tuning the pH, the macroscopic appearance of the UC₂₂AMPM−AlCl₃ system switched between transparent solutions and milky dispersion, concomitant with a viscosity variation of one order of magnitude. Importantly, the UC₂₂AMPM−AlCl₃ systems showed a constant viscosity of 40 mPa·s at 80 °C and 170 s⁻¹ for 120 min, indicative of good heat and shear resistances. The metal-containing viscoelastic fluids are expected to be good candidates for high-temperature reservoir hydraulic fracturing. Full article

Liquid marbles are droplets encapsulated by a layer of hydrophobic nanoparticles and have been extensively employed in digital microfluidics and lab-on-a-chip systems in recent years. In this study, magnetic liquid marbles were used to manipulate nonmagnetic liquid marbles. To achieve this purpose, a ferrofluid liquid marble (FLM) was employed and attracted toward an electromagnet, resulting in an impulse to a water liquid marble (WLM) on its way to the electromagnet. It was observed that the manipulation of the WLM by the FLM was similar to the collision of billiard balls except that the liquid marbles exhibited an inelastic collision. Taking the FLM as the projectile ball and the WLM as the other target balls, one can adjust the displacement and direction of the WLM precisely, similar to an expert billiard player. Firstly, the WLM displacement can be adjusted by altering the liquid marble volumes, the initial distances from the electromagnet, and the coil current. Secondly, the WLM direction can be adjusted by changing the position of the WLM relative to the connecting line between the FLM center and the electromagnet. Results show that when the FLM or WLM volume increases by five times, the WLM shooting distance approximately increases by 200% and decreases by 75%, respectively. Full article

Adaptive noise cancellation is a useful linear technique to attenuate unwanted background noise that cannot be removed using traditional frequency-selective filters. Usually, this is due to the signal and noise co-existing in the same frequency band. This paper tests a weighted least mean squares (WLMS) algorithm on a stethoscope system for use in detecting coronary artery disease in the presence of background noise. Each stethoscope is equipped with two microphones: one used to detect heart signals and one used to detect background noise. The WLMS method was used for four different sources of background noise whilst measuring a heartbeat, including a single tone, multiple tones, hospital/clinic noise, and breathing noise. The magnitude-squared coherence between both microphones was unity for the tone scenarios, resulting in complete attenuation. For the other background noise sources, a less-than-unity magnitude-squared coherence resulted in minor and no attenuation. Thus, the coherence function is a tool that can be used to predict the amount of attenuation achievable by linear adaptive noise-cancellation techniques, such as WLMS, as presented in this article. Full article

There are economic and technical challenges to overcome when increasing resource recovery from low permeability reservoirs. For such reservoirs, the hydraulic fracturing plan with the development of clean and less expensive fracturing fluid plays a vital aspect in meeting the energy supply chain. Numerous recent published studies have indicated that research on worm-like micelles (WLMs) based on viscoelastic surfactant (VES) fluid has progressed substantially. This study looks at the development of CO₂-sensitive viscoelastic fracturing fluid (CO₂-SVFF), its applications, benefits, limitations, and drawbacks of conventional fracturing fluids. The switchable viscoelasticity of CO₂-SVFF system signifies how reusing of this fluid is attained. Compared to conventional surfactants, the CO₂-SVFF system can be switched to high viscosity (to fracture formation and transporting proppants) and low viscosity (easy removal after causing fracture). The effect of pH, conductivity, temperature, and rheological behaviors of CO₂-SVFFs are also highlighted. Further, the aid of Gemini surfactants and nanoparticles (NPs) with low concentrations in CO₂-SVFF can improve viscoelasticity and extended stability to withstand high shear rates and temperatures during the fracturing process. These studies provide insight into future knowledge that might lead to a more environmentally friendly and successful CO₂-SVFFs in low-permeability reservoirs. Despite the increased application of CO₂-SVFFs, there are still several challenges (i.e., formation with high-temperature range, pressure, and salinity). Full article

Fe₃O₄@ZnO nanocomposites (NCs) were synthesized to improve the stability of the wormlike micelle (WLM) network structure of viscoelastic surfactant (VES) fracturing fluid and were characterized by Fourier transform infrared spectrometry (FT-IR), scanning electron microscopy (SEM), energy dispersive spectrometry (EDS), X-ray diffraction (XRD) and vibrating sample magnetometry (VSM). Then, an NC-enhanced viscoelastic surfactant solution as a fracturing fluid (NC-VES) was prepared, and its properties, including settlement stability, interactions between NCs and WLMs, proppant-transporting performance and gel-breaking properties, were systematically studied. More importantly, the influences of the NC concentration, shear rate, temperature and pH level on the stability of NC-VES were systematically investigated. The experimental results show that the NC-VES with a suitable content of NCs (0.1 wt.%) shows superior stability at 95 °C or at a high shear rate. Meanwhile, the NC-VES has an acceptable wide pH stability range of 6–9. In addition, the NC-VES possesses good sand-carrying performance and gel-breaking properties, while the NCs can be easily separated and recycled by applying a magnetic field. The temperature-resistant, stable and environmentally friendly fracturing fluid opens an opportunity for the future hydraulic fracturing of unconventional reservoirs. Full article

The rapid development of Internet of Things (IoT) technology, together with mobile network technology, has created a never-before-seen world of interconnection, evoking research on how to make it vaster, faster, and safer. To support the ongoing fight against the malicious misuse of networks, in this paper we propose a novel algorithm called AMDES (unmanned aerial system multifractal analysis intrusion detection system) for spoofing attack detection. This novel algorithm is based on both wavelet leader multifractal analysis (WLM) and machine learning (ML) principles. In earlier research on unmanned aerial systems (UAS), intrusion detection systems (IDS) based on multifractal (MF) spectral analysis have been used to provide accurate MF spectrum estimations of network traffic. Such an estimation is then used to detect and characterize flooding anomalies that can be observed in an unmanned aerial vehicle (UAV) network. However, the previous contributions have lacked the consideration of other types of network intrusions commonly observed in UAS networks, such as the man in the middle attack (MITM). In this work, this promising methodology has been accommodated to detect a spoofing attack within a UAS. This methodology highlights a robust approach in terms of false positive performance in detecting intrusions in a UAS location reporting system. Full article

We herein report a simultaneous frequency stabilization of two 780-nm external cavity diode lasers using a precision wavelength meter (WLM). The laser lock performance is characterized by the Allan deviation measurement in which we find ${\sigma }_y={10}^{-12}$ at an averaging time of 1000 s. We also obtain spectral profiles through a heterodyne spectroscopy, identifying the contribution of white and flicker noises to the laser linewidth. The frequency drift of the WLM is measured to be about 2.0(4) MHz over 36 h. Utilizing the two lasers as a cooling and repumping field, we demonstrate a magneto-optical trap of ${}^{87}$Rb atoms near a high-finesse optical cavity. Our laser stabilization technique operates at broad wavelength range without a radio frequency element. Full article

This paper examines a new study on the synergistic effect of magnetic nanoparticles and wormlike micelles (WLMs) on drag reduction. Fe₃O₄ magnetic nanoparticles (FE-NPs) are utilized to improve the performance of viscoelastic surfactant (VES) solutions used as fracturing fluids. The chemical composition and micromorphology of the FE-NPs were analyzed with FT-IR and an electron microscope. The stability and interaction of the WLM-particle system were studied by zeta potential and cryo-TEM measurements. More importantly, the influences of the temperature, FE-NP concentration, magnetic field intensity, and direction on the drag reduction rate of WLMs were systematically investigated in a circuit pipe flow system with an electromagnetic unit. The experimental results show that a suitable content of magnetic nanoparticles can enhance the settlement stability and temperature resistance of WLMs. A magnetic field along the flow direction of the fracturing fluid can improve the drag reduction performance of the magnetic WLM system. However, under a magnetic field perpendicular to the direction of fluid flow, an additional flow resistance is generated by the vertical chaining behavior of FE-NPs, which is unfavorable for the drag reduction performance of magnetic VES fracturing fluids. This study may shed light on the mechanism of the synergistic drag reduction effects of magnetic nanoparticles and wormlike micelles. Full article

The controlled design of robust, well reproducible, and functional nanomaterials made according to simple processes is of key importance to envision future applications. In the field of porous materials, tuning nanoparticle features such as specific area, pore size and morphology by adjusting simple parameters such as pH, temperature or solvent is highly needed. In this work, we address the tunable control of the pore morphology of mesoporous silica (MS) nanoparticles (NPs) with the sol-gel reaction temperature (T_sg). We show that the pore morphology of MS NPs alone or of MS shell covering iron oxide nanoparticles (IO NPs) can be easily tailored with T_sg orienting either towards stellar (ST) morphology (large radial pore of around 10 nm) below 80 °C or towards a worm-like (WL) morphology (small randomly oriented pores channel network, of 3–4 nm pore size) above 80 °C. The relaxometric and magnetothermal features of IO@STMS or IO@WLMS core shell NPs having respectively stellar or worm-like morphologies are compared and discussed to understand the role of the pore structure for MRI and magnetic hyperthermia applications. Full article

One-year dietary quality change according to the preceding maximum weight in a lifestyle intervention program (PREDIMED-Plus trial, 55–75-year-old overweight or obese adults; n = 5695) was assessed. A validated food frequency questionnaire was used to assess dietary intake. A total of 3 groups were made according to the difference between baseline measured weight and lifetime maximum reported weight: (a) participants entering the study at their maximum weight, (b) moderate weight loss maintainers (WLM), and (c) large WLM. Data were analyzed by General Linear Model. All participants improved average lifestyle. Participants entering the study at their maximum weight were the most susceptible to improve significantly their dietary quality, assessed by adherence to Mediterranean diet, DII and both healthful and unhealthful provegetarian patterns. People at maximum weight are the most benefitted in the short term by a weight management program. Long term weight loss efforts may also reduce the effect of a weight management program. Full article

This study investigated the effects of collagen hydrolysates (CH) on language cognitive function and brain structure. In this open-label study, 5 g CH was administered once a day for 4 weeks to 30 healthy participants aged 49–63 years. The primary outcome measures were the brain healthcare quotients based on gray matter volume (GM-BHQ) and fractional anisotropy (FA-BHQ). The secondary outcome measures were changes in scores between week 0 and week 4 for word list memory (WLM) and standard verbal paired associate learning (S-PA) tests as well as changes in the physical, mental, and role/social component summary scores of the Short Form-36(SF-36) quality of life instrument. CH ingestion resulted in significant improvements in FA-BHQ (p = 0.0095), a measure of brain structure, as well in scores for the WLM (p = 0.0046) and S-PA (p = 0.0007) tests, which measure cognitive function. There were moderate correlations between the change in WLM score and the change in GM-BHQ (r = 0.4448; Spearman’s rank correlation) and between the change in S-PA score and the change in FA-BHQ (r = 0.4645). Daily ingestion of CH changed brain structure and improved language cognitive function. Full article

Inadequate vitamin and mineral intake is documented among individuals with obesity, but is unknown among long-term weight loss maintainers (WLM). This study examined dietary quality and micronutrient adequacy among WLMs in a commercial weight management program. Participants were 1207 WLM in Weight Watchers (WW) who had maintained a 9.1 kg or greater weight loss (29.7 kg on average) for 3.4 years and had a body mass index (BMI) of 28.3 kg/m². A control group of weight stable adults with obesity (controls; N = 102) had a BMI of 41.1 kg/m². Measures included the Diet History Questionnaire-II, Healthy Eating Index-2015 (HEI), and Dietary References Intakes. WLM versus controls had a 10.1 point higher HEI score (70.2 (69.7–70.7) vs. 60.1 (58.4–61.8); p = 0.0001) and greater odds of meeting recommendations for copper (OR = 5.8 (2.6–13.1)), magnesium (OR = 2.9 (1.8–4.7)), potassium (OR = 4.7 (1.4–16.5)), vitamin A (OR = 2.8 (1.7–4.8)), vitamin B6 (OR = 2.9 (1.6–5.2)), and vitamin C (OR = 5.0 (2.8–8.8)). WLM, compared to controls, also reported higher percentages of calories from carbohydrates (50.3% (49.7–50.8) vs. 46.7% (44.8–48.7); p = 0.0001) and protein (18.2% (18.0–18.5) vs. 15.9% (15.1–16.6); p = 0.0001) and lower calories from fat (32.3% (31.9–32.8) vs. 37.4% (35.8–38.9); p = 0.0001). Long-term weight loss maintenance in a widely used commercial program was associated with a healthier diet pattern, including consuming foods with higher micronutrient density. Full article