The X-Men are gone. The world has grown to fear and loath the mutants especially after an incident four years earlier. Reed Strucker (Stephen Moyer) has been prosecuting mutant terrorists and for the last 5 years, he's been a member of the Mutant Task Force. His son Andy gets bullied at school and his mutant powers are unleashed. He and sister Lauren are revealed. Reed is forced to go on the run with his family. Reed tracks down the Mutant Underground where he offers imprisoned Lorna Dane in return for transit to Mexico. Jace Turner is a Sentinel Services agent driven to catch fugitive mutants due to a personal loss.
This is as good as network live action X-Men TV show is probably going to get. It gets to the main theme of persecution of minorities. It's not prestige TV. It doesn't have the dark style or experimentation. It has action with some limits. There is a bit of network blandness that bleeds into the show. It has a lot of lead characters but is able to maintain focus on them. The brother can be annoying which happens with some rebellious youth. I would love more daring in the writing but this is fine for network TV. At least, it's not Inhumans.