Cryo electron microscopy of SARS-CoV-2 spike in prefusion state
Melero R, Sorzano COS, Foster B, Vilas JL, Martínez M, Marabini R, Ramírez-Aportela E, Sanchez-Garcia R, Herreros D, Del Caño L, Losana P, Fonseca-Reyna YC, Conesa P, Wrapp D, Chacon P, McLellan JS, Tagare HD, Carazo JM
IUCrJ (2020) 7 [ Pubmed: 33063791 DOI: 10.1107/s2052252520012725 ]
Image sets:
Cryo electron microscopy of SARS-CoV-2 stabilized spike in prefusion state
Melero R, Sorzano COS, Foster B, Vilas JL, Martínez M, Marabini R, Ramírez-Aportela E, Sanchez-Garcia R, Herreros D, Del Caño L, Losana P, Fonseca-Reyna YC, Conesa P, Wrapp D, Chacon P, McLellan JS, Tagare HD, Carazo JM
IUCrJ (2020) 7 [ Pubmed: 33063791 DOI: 10.1107/s2052252520012725 ]
Image sets:
SARS-CoV-2 spike in prefusion state
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 6zow
Q-score: 0.451
Melero R, Sorzano COS, Foster B, Vilas JL, Martinez M, Marabini R, Ramirez-Aportela E, Sanchez-Garcia R, Herreros D, Del Cano L, Losana P, Fonseca-Reyna YC, Conesa P, Wrapp D, Chacon P, McLellan JS, Tagare HD, Carazo JM
IUCrJ (2020) 7 pp. 1059-1069 [ DOI: doi:10.1107/S2052252520012725 Pubmed: 33063791 ]
- Water (18 Da, Ligand)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Alpha-d-mannopyranose (180 Da, Ligand)
- Dimethyl sulfoxide (78 Da, Ligand)
- Spike homotrimer in prefusion state (Complex from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 spike in prefusion state (flexibility analysis, 1-up closed conformation)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6zp5
Q-score: 0.417
Melero R, Sorzano COS, Foster B, Vilas JL, Martinez M, Marabini R, Ramirez-Aportela E, Sanchez-Garcia R, Herreros D, Del Cano L, Losana P, Fonseca-Reyna YC, Conesa P, Wrapp D, Chacon P, McLellan JS, Tagare HD, Carazo JM
IUCrJ (2020) 7 pp. 1059-1069 [ DOI: doi:10.1107/S2052252520012725 Pubmed: 33063791 ]
- Sars-cov-2 spike in prefusion state (flexibility analysis, 1-up closed conformation) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Alpha-d-mannopyranose (180 Da, Ligand)
- Dimethyl sulfoxide (78 Da, Ligand)
SARS-CoV-2 spike in prefusion state (flexibility analysis, 1-up open conformation)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6zp7
Q-score: 0.368
Melero R, Sorzano COS, Foster B, Vilas JL, Martinez M, Marabini R, Ramirez-Aportela E, Sanchez-Garcia R, Herreros D, Del Cano L, Losana P, Fonseca-Reyna YC, Conesa P, Wrapp D, Chacon P, McLellan JS, Tagare HD, Carazo JM
IUCrJ (2020) 7 pp. 1059-1069 [ DOI: doi:10.1107/S2052252520012725 Pubmed: 33063791 ]
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 spike in prefusion state (flexibility analysis, 1-up open conformation) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Alpha-d-mannopyranose (180 Da, Ligand)
- Dimethyl sulfoxide (78 Da, Ligand)
SARS-CoV-2 stabilized spike in prefusion state (1-up conformation)
Melero R, Sorzano COS, Foster B, Vilas JL, Martinez M, Marabini R, Ramirez-Aportela E, Sanchez-Garcia R, Herreros D, Del Cano L, Losana P, Fonseca-Reyna YC, Conesa P, Wrapp D, Chacon P, McLellan JS, Tagare HD, Carazo JM
IUCrJ (2020) 7 pp. 1059-1069 [ DOI: doi:10.1107/S2052252520012725 Pubmed: 33063791 ]