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A comparative analysis of transcriptomics of newly diagnosed multiple myeloma: exploring drug repurposing
Frontiers
Multiple myeloma (MM) is an incurable malignant plasma cell disorder characterized by the infiltration of clonal plasma cells in the bone...
7 months ago
RefEx, a reference gene expression dataset as a web tool for the functional analysis of genes
Nature
Gene expression data are exponentially accumulating; thus, the functional annotation of such sequence data from metadata is urgently...
86 months ago
Human transcriptome array for high-throughput clinical studies
PNAS
A 6.9 million-feature oligonucleotide array of the human transcriptome [Glue Grant human transcriptome (GG-H array)] has been developed for high-throughput and...
32 months ago
Genomic signature of parity in the breast of premenopausal women
Breast Cancer Research
The main objective of this study was to assess the parity-associated gene expression differences in the breast of premenopausal women.
67 months ago
A cross comparison of technologies for the detection of microRNAs in clinical FFPE samples of hepatoblastoma patients
Nature
We have compared three independent platforms (next generation sequencing, microarray and NanoString) for profiling microRNAs (miRNAs) using clinical FFPE...
113 months ago
Systematic evaluation of RNA quality, microarray data reliability and pathway analysis in fresh, fresh frozen and formalin-fixed paraffin-embedded tissue samples
Nature
Formalin-fixed paraffin-embedded (FFPE) tissues are valuable resources commonly used in pathology. However, formalin fixation modifies...
78 months ago
Evaluation of frozen tissue-derived prognostic gene expression signatures in FFPE colorectal cancer samples
Nature
Defining molecular features that can predict the recurrence of colorectal cancer (CRC) for stage II-III patients remains challenging in...
98 months ago
Microarray profiling of miRNA and mRNA expression in Rag2 knockout and wild-type mouse spleens
Nature
We describe a comprehensive dataset containing alterations in the expression of both miRNAs and mRNAs in Rag2 KO mice compared to their wild type counterparts.
82 months ago
Inferring tumour purity and stromal and immune cell admixture from expression data
Nature
A method that uses gene expression signatures to infer the fraction of stromal and immune cells in tumour samples.
133 months ago
A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies
Nature
In this study, we describe a framework for comparisons across platforms and laboratories. We have attempted to include nearly all the available commercial and...
220 months ago