THC intoxication has been shown to impair cognitive function on a number of levels—from basic motor coordination to more complex tasks, such as the ability to plan, organize, solve problems, make decisions, remember, and control emotions and behavior.

As children develop they are better able to recruit brain regions associated with WM encoding and maintenance (e.g. MFG, IPS) and their performance on WM tasks improves in parallel to the structural and functional development of these structures.

Those who use cannabis more often than weekly in adolescence are more likely to develop dependence, use other illicit drugs, and develop psychotic symptoms and psychosis [ 1].

Several studies have reported significant associations between frequent cannabis use and alterations in subcortical and cerebellar volumes, cortical thickness, and surface-based morphometry in adolescents and young adults [7].